Click here to switch to the map view.

The map label for this gene is mpg1 [H]

Identifier: 15922616

GI number: 15922616

Start: 2292895

End: 2293968

Strand: Direct

Name: mpg1 [H]

Synonym: ST2284

Alternate gene names: 15922616

Gene position: 2292895-2293968 (Clockwise)

Preceding gene: 15922615

Following gene: 15922617

Centisome position: 85.09

GC content: 29.61

Gene sequence:

>1074_bases
ATGGTCTCAGCTATAGTATTAGCTGGAGGATATGCAACTAGATTAAGACCGTTAAGTCTCACAAAACCTAAAGCTCTTTT
ACCCATTTTGGATAAGCCTCTTTTGGATTATATTTTAGATTCATTAGAAATAGCTGGAATAAATGAGGTATATTTATCCC
TTCGTGTTATGGCAGACAAAATTTTGTCTCATATTGAAGGTGAAAATAGAAAAGTAATTCCAGTAATAGAGAAAGAGAGA
CTAGGAGATGCAGGACCATTGAAATTGATCTCACAAAGATATAATCTATCTGATGATGTTCTTGTAATATACGGAGATAT
TTATAATGAATTGGATATAAAATCATTACTTAAATTTCATGAAAAAGAAGGTTGTGATGCAACGATAGTAGGAAAACCTG
TAGAAGATCCTAGAAGATATGGTGTTTTAATAACGGAGGGAGAACGCTTAGTACAAATAATAGAAAAACCAAAGAATCCG
GTATCTAACCTTATAAATGCGGGTATATATGTATTTAAGAAAAAATTATTAGAAAAAATAGATGGGCAAAGCATAGCTAA
GAATTTTCTACCAAAACTTCTATCTGATAATACTTGTATAGCTGTTTATAAATATGATGGATTATGGATGGATATTGGAG
TACCATCAGATTACATAAGAATAAATTTACAACTTCTATCTTTAAAATATCCTAAGGGATATATTAATGAAGAAGCAAAA
GTGAGTGAAAAAGTTAACCTAATTCCACCTTATTATATAAGTAGTGGCGTAAATATAAGTGAGGACTCATTCATATTTAA
TAGTATTATTGGTAAGAATACGTCAATTGGTAATGGTGTTTATATAGACCAAAGTATATTAATGGAAGATGTTAAAGTCG
ATAGTTTTAGTTATATTAGAGATAGTATCTTAGGTGATAAAGATAATTTAGGAAAATGGGTTAGATTAGATTCAGTTATT
TTGGGTGATGAGGTAGTAATATATGATGGTGTATTTGTAAATAGAGATACAATAATTTTACCCTATAAAGAAGTTAATGA
GTCCGTATACGATAAGGGAAAAATAATATTGTGA

Upstream 100 bases:

>100_bases
TGAACGCATGGTGGAATTTAGTAAATTGGGACGAAGCAGATAAAAAATTGCAGAAATATCTTAATAAGTAATTTTTTTAT
CTTTGTATCCTATATTTCTT

Downstream 100 bases:

>100_bases
CTCTACTCTCTTCTTTTAATACTCTAGAGATATTATGTGAGAAAGCTTCTGCTATCACTATTAATTATTTTAATATTTGT
AGCATTATCTAGCACGGTAA

Product: mannose-1-phosphate guanylyltransferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MVSAIVLAGGYATRLRPLSLTKPKALLPILDKPLLDYILDSLEIAGINEVYLSLRVMADKILSHIEGENRKVIPVIEKER
LGDAGPLKLISQRYNLSDDVLVIYGDIYNELDIKSLLKFHEKEGCDATIVGKPVEDPRRYGVLITEGERLVQIIEKPKNP
VSNLINAGIYVFKKKLLEKIDGQSIAKNFLPKLLSDNTCIAVYKYDGLWMDIGVPSDYIRINLQLLSLKYPKGYINEEAK
VSEKVNLIPPYYISSGVNISEDSFIFNSIIGKNTSIGNGVYIDQSILMEDVKVDSFSYIRDSILGDKDNLGKWVRLDSVI
LGDEVVIYDGVFVNRDTIILPYKEVNESVYDKGKIIL

Sequences:

>Translated_357_residues
MVSAIVLAGGYATRLRPLSLTKPKALLPILDKPLLDYILDSLEIAGINEVYLSLRVMADKILSHIEGENRKVIPVIEKER
LGDAGPLKLISQRYNLSDDVLVIYGDIYNELDIKSLLKFHEKEGCDATIVGKPVEDPRRYGVLITEGERLVQIIEKPKNP
VSNLINAGIYVFKKKLLEKIDGQSIAKNFLPKLLSDNTCIAVYKYDGLWMDIGVPSDYIRINLQLLSLKYPKGYINEEAK
VSEKVNLIPPYYISSGVNISEDSFIFNSIIGKNTSIGNGVYIDQSILMEDVKVDSFSYIRDSILGDKDNLGKWVRLDSVI
LGDEVVIYDGVFVNRDTIILPYKEVNESVYDKGKIIL
>Mature_357_residues
MVSAIVLAGGYATRLRPLSLTKPKALLPILDKPLLDYILDSLEIAGINEVYLSLRVMADKILSHIEGENRKVIPVIEKER
LGDAGPLKLISQRYNLSDDVLVIYGDIYNELDIKSLLKFHEKEGCDATIVGKPVEDPRRYGVLITEGERLVQIIEKPKNP
VSNLINAGIYVFKKKLLEKIDGQSIAKNFLPKLLSDNTCIAVYKYDGLWMDIGVPSDYIRINLQLLSLKYPKGYINEEAK
VSEKVNLIPPYYISSGVNISEDSFIFNSIIGKNTSIGNGVYIDQSILMEDVKVDSFSYIRDSILGDKDNLGKWVRLDSVI
LGDEVVIYDGVFVNRDTIILPYKEVNESVYDKGKIIL

Specific function: Glycogen biosynthesis; first step. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=367, Percent_Identity=30.5177111716621, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI11761619, Length=394, Percent_Identity=28.4263959390863, Blast_Score=168, Evalue=8e-42,
Organism=Homo sapiens, GI31881779, Length=438, Percent_Identity=22.6027397260274, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI45447090, Length=438, Percent_Identity=22.6027397260274, Blast_Score=92, Evalue=6e-19,
Organism=Escherichia coli, GI1789837, Length=382, Percent_Identity=23.2984293193717, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788351, Length=201, Percent_Identity=29.3532338308458, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790224, Length=249, Percent_Identity=24.8995983935743, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI133931050, Length=367, Percent_Identity=30.7901907356948, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI17509979, Length=410, Percent_Identity=25.1219512195122, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17509981, Length=400, Percent_Identity=24.5, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320148, Length=364, Percent_Identity=31.043956043956, Blast_Score=170, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6320417, Length=128, Percent_Identity=29.6875, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355443, Length=359, Percent_Identity=34.2618384401114, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24644084, Length=359, Percent_Identity=34.2618384401114, Blast_Score=179, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 40076; Mature: 40076

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSAIVLAGGYATRLRPLSLTKPKALLPILDKPLLDYILDSLEIAGINEVYLSLRVMADK
CCEEEEEECCCHHHEEECCCCCCCHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ILSHIEGENRKVIPVIEKERLGDAGPLKLISQRYNLSDDVLVIYGDIYNELDIKSLLKFH
HHHHHCCCCCEEEEEECHHHCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHH
EKEGCDATIVGKPVEDPRRYGVLITEGERLVQIIEKPKNPVSNLINAGIYVFKKKLLEKI
HHCCCCEEEECCCCCCHHHEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DGQSIAKNFLPKLLSDNTCIAVYKYDGLWMDIGVPSDYIRINLQLLSLKYPKGYINEEAK
CCHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCCCEEEEEEEEEEEECCCCCCCCCHH
VSEKVNLIPPYYISSGVNISEDSFIFNSIIGKNTSIGNGVYIDQSILMEDVKVDSFSYIR
HHCCCCCCCCHHHCCCCCCCCCCHHHHHHHCCCCCCCCCEEECHHHHHHHHCCCHHHHHH
DSILGDKDNLGKWVRLDSVILGDEVVIYDGVFVNRDTIILPYKEVNESVYDKGKIIL
HHHCCCCCCCCCEEEECEEEECCEEEEECCEEECCCEEEECHHHHCHHHHCCCCEEC
>Mature Secondary Structure
MVSAIVLAGGYATRLRPLSLTKPKALLPILDKPLLDYILDSLEIAGINEVYLSLRVMADK
CCEEEEEECCCHHHEEECCCCCCCHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ILSHIEGENRKVIPVIEKERLGDAGPLKLISQRYNLSDDVLVIYGDIYNELDIKSLLKFH
HHHHHCCCCCEEEEEECHHHCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHH
EKEGCDATIVGKPVEDPRRYGVLITEGERLVQIIEKPKNPVSNLINAGIYVFKKKLLEKI
HHCCCCEEEECCCCCCHHHEEEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
DGQSIAKNFLPKLLSDNTCIAVYKYDGLWMDIGVPSDYIRINLQLLSLKYPKGYINEEAK
CCHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCCCEEEEEEEEEEEECCCCCCCCCHH
VSEKVNLIPPYYISSGVNISEDSFIFNSIIGKNTSIGNGVYIDQSILMEDVKVDSFSYIR
HHCCCCCCCCHHHCCCCCCCCCCHHHHHHHCCCCCCCCCEEECHHHHHHHHCCCHHHHHH
DSILGDKDNLGKWVRLDSVILGDEVVIYDGVFVNRDTIILPYKEVNESVYDKGKIIL
HHHCCCCCCCCCEEEECEEEECCEEEEECCEEECCCEEEECHHHHCHHHHCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]