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The map label for this gene is tktB [C]

Identifier: 15922599

GI number: 15922599

Start: 2277160

End: 2277981

Strand: Direct

Name: tktB [C]

Synonym: ST2268

Alternate gene names: 15922599

Gene position: 2277160-2277981 (Clockwise)

Preceding gene: 15922590

Following gene: 15922600

Centisome position: 84.5

GC content: 36.01

Gene sequence:

>822_bases
ATGGAAGGAGGGAGACGTGATGGAATTCCAATATCAATAGAGGAGCTAAATAAGTTAAAGAATATTGCTGAAAGAGCAAG
AAGAAATGTAGTAAAGATGCTATTTTATGATCAAACAATCCATGTTGGTTCATCGCTTAGTAGTATAGAGATATTAACTA
CATTATTGTTTAGATATATAAGGGAAGGAAAGGATCCTATAAATAGGGATTGGTTAATACTAAGTAAAGGGCATGCAGCA
CCCGCATTATATGCTATTTTGGTAGAAAAAGGGTATATTAATGAAGATGAATTATGGAAAATCCAGGATATCTCTGGCCT
ATTACAAGGACATCCAGAAATTCATATACCTGGTATTGATATGTCTACCGGAAGTTTAGGACAAGGTTTAAGTTTCGGTA
TAGGTGTTGCCCAAGGAATAAAAATGAGAGGAGGAAATGGAAGAGTATTTGTAATAATGGGAGACGGAGAGCAAGATGAG
GGTGAAGTTTGGGAAGCTATGACTCATGCAGTTACTAGAAAATTAGATAATATTATTGCATTCATAGAAATGAACGGTTT
TCAGTTAGATGCTGCAACATCTGAAGTAAAACCAAAAGATTTCTTACCAGATGTATGGAAGGCTGTTGGTTGGAAAACGT
TAAGTTGTGATGGTCATGATTTTATAAGTTTAATAAATACAATCGAGGAAGCATTAAAGGCAAAGGCTCCGGTAGTTATT
TTTGCTAAGACAAGAAGAGGTATGGGATTCAAGGCGATAGAAAATACTGAAAAACAGAGGGCGAGTCCAGATGATGCAAA
GAAGTACCTTACCAATGCGTGA

Upstream 100 bases:

>100_bases
AATACTAATAACTGCCTTGAATATCTTTCCATATACTATACTTCAAAAAAACTTATAATTAAGAATTGTTTATTATCCGC
GGGGGCTTGGTTTTGCACCA

Downstream 100 bases:

>100_bases
TACTTTCGGTAGATTATTAGCTGAATTGGGAGAGAAAAATAAAGATATAATAGTTATTACTGCAGATGTTGGAAACTCTA
CTAGAGCTATGTACTTTAGG

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MEGGRRDGIPISIEELNKLKNIAERARRNVVKMLFYDQTIHVGSSLSSIEILTTLLFRYIREGKDPINRDWLILSKGHAA
PALYAILVEKGYINEDELWKIQDISGLLQGHPEIHIPGIDMSTGSLGQGLSFGIGVAQGIKMRGGNGRVFVIMGDGEQDE
GEVWEAMTHAVTRKLDNIIAFIEMNGFQLDAATSEVKPKDFLPDVWKAVGWKTLSCDGHDFISLINTIEEALKAKAPVVI
FAKTRRGMGFKAIENTEKQRASPDDAKKYLTNA

Sequences:

>Translated_273_residues
MEGGRRDGIPISIEELNKLKNIAERARRNVVKMLFYDQTIHVGSSLSSIEILTTLLFRYIREGKDPINRDWLILSKGHAA
PALYAILVEKGYINEDELWKIQDISGLLQGHPEIHIPGIDMSTGSLGQGLSFGIGVAQGIKMRGGNGRVFVIMGDGEQDE
GEVWEAMTHAVTRKLDNIIAFIEMNGFQLDAATSEVKPKDFLPDVWKAVGWKTLSCDGHDFISLINTIEEALKAKAPVVI
FAKTRRGMGFKAIENTEKQRASPDDAKKYLTNA
>Mature_273_residues
MEGGRRDGIPISIEELNKLKNIAERARRNVVKMLFYDQTIHVGSSLSSIEILTTLLFRYIREGKDPINRDWLILSKGHAA
PALYAILVEKGYINEDELWKIQDISGLLQGHPEIHIPGIDMSTGSLGQGLSFGIGVAQGIKMRGGNGRVFVIMGDGEQDE
GEVWEAMTHAVTRKLDNIIAFIEMNGFQLDAATSEVKPKDFLPDVWKAVGWKTLSCDGHDFISLINTIEEALKAKAPVVI
FAKTRRGMGFKAIENTEKQRASPDDAKKYLTNA

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=255, Percent_Identity=36.8627450980392, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI4507521, Length=255, Percent_Identity=36.8627450980392, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI133778974, Length=256, Percent_Identity=33.984375, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI225637459, Length=253, Percent_Identity=28.8537549407115, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI225637463, Length=147, Percent_Identity=36.0544217687075, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI225637461, Length=147, Percent_Identity=36.0544217687075, Blast_Score=88, Evalue=7e-18,
Organism=Escherichia coli, GI1788808, Length=240, Percent_Identity=30.4166666666667, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI48994911, Length=266, Percent_Identity=29.3233082706767, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17539652, Length=258, Percent_Identity=34.4961240310078, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319593, Length=231, Percent_Identity=29.4372294372294, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6325331, Length=199, Percent_Identity=32.1608040201005, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24666278, Length=254, Percent_Identity=34.251968503937, Blast_Score=138, Evalue=3e-33,
Organism=Drosophila melanogaster, GI45551847, Length=254, Percent_Identity=34.251968503937, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI45550715, Length=254, Percent_Identity=34.251968503937, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24645119, Length=218, Percent_Identity=35.7798165137615, Blast_Score=124, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 30280; Mature: 30280

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGGRRDGIPISIEELNKLKNIAERARRNVVKMLFYDQTIHVGSSLSSIEILTTLLFRYI
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHH
REGKDPINRDWLILSKGHAAPALYAILVEKGYINEDELWKIQDISGLLQGHPEIHIPGID
HCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEEHHHHHHHHCCCCCEEECCCC
MSTGSLGQGLSFGIGVAQGIKMRGGNGRVFVIMGDGEQDEGEVWEAMTHAVTRKLDNIIA
CCCCCCCCCCHHHHHHHCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEE
FIEMNGFQLDAATSEVKPKDFLPDVWKAVGWKTLSCDGHDFISLINTIEEALKAKAPVVI
EEEECCEEEECCCCCCCCHHCCHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHCCCCEEE
FAKTRRGMGFKAIENTEKQRASPDDAKKYLTNA
EEECCCCCCCHHHHCCHHHCCCHHHHHHHHCCC
>Mature Secondary Structure
MEGGRRDGIPISIEELNKLKNIAERARRNVVKMLFYDQTIHVGSSLSSIEILTTLLFRYI
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHH
REGKDPINRDWLILSKGHAAPALYAILVEKGYINEDELWKIQDISGLLQGHPEIHIPGID
HCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEEHHHHHHHHCCCCCEEECCCC
MSTGSLGQGLSFGIGVAQGIKMRGGNGRVFVIMGDGEQDEGEVWEAMTHAVTRKLDNIIA
CCCCCCCCCCHHHHHHHCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEE
FIEMNGFQLDAATSEVKPKDFLPDVWKAVGWKTLSCDGHDFISLINTIEEALKAKAPVVI
EEEECCEEEECCCCCCCCHHCCHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHCCCCEEE
FAKTRRGMGFKAIENTEKQRASPDDAKKYLTNA
EEECCCCCCCHHHHCCHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]