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The map label for this gene is moaA [C]

Identifier: 15922501

GI number: 15922501

Start: 2174610

End: 2175581

Strand: Direct

Name: moaA [C]

Synonym: ST2174

Alternate gene names: 15922501

Gene position: 2174610-2175581 (Clockwise)

Preceding gene: 15922500

Following gene: 15922503

Centisome position: 80.7

GC content: 33.54

Gene sequence:

>972_bases
GTGAAATTAGAGAGAGTTAAAGAACCAATTCCTCTTATTGGGCATATAGCTTTTGGCATAATTGACCGTGGTACTAACGT
TCTTCAAGTTCGTCCATTTAGCAATTGCCCAATGTCTTGTATATTTTGTTCAGTAGATGCTGGTCCTAATTCTAGATCGA
GAGTGACTGAGTATATTGTAGATGCTGACCATTTAATTAATTGGGTTAATTATGTTGTTGATAGAAAAATTCATCAAGTA
TCAATTTTAATTGATGGTGTGGGTGAACCTATATTACATCCAGATATTGTGAAAATTGTAAAAGGAATAAAGGAAAATAG
GAAAGTATTTGAGGTAGCAATTGAAACTCACGGTTTACCATTAAATGAGAGACTAATAAAAGGACTAGCTAATGCTGGAC
TAGATAGGATTAATCTTTCGTTAGATTCCTTAGATGAGAATAAGGCTAAATATCTTAGTGGTCATAAAGGTTATAATGTT
TCTAAAATATTGAAAATGATAGATCTAGCATTAAATGAAGGGTTAAAGATTATGTTAACTCCAGTGTGGATTAAAGGAAT
GAATGATGAAGATATAATTAATCTTGTGAAGTTTGGAAAAGAGAAAGGACTATCTTTCGGAATTCAAAAATATGTTGCCC
ATCCTAGAGGAAGAAAGGTTGGTAAAGAGGTTGGTTGGAAAGAGTTCAAAGAATTTTTATCAAAAATTGGTGAAATGTTA
GATGTCAATCTCTTTCTCTCTCCTTCTCAGTTCAAGGTATTTCCAGATGTTAGGCTAGGCCCAGTAATGGATGTTGGTGA
GAAAGTAGTAGGAGAAGTTGTGCTGGATGGTTGGATGAAGAATGAGGTCATAATAACTGCTAGAGGAAGAGTTATTACAG
TAGTTGGTGTTAGTGATGTTCCTAAGGGTATCTCATTAAAAGTTAAAATAAGTAGAAATAAGGATGAAATTTACTTAGCT
AGGCTTAGCTAA

Upstream 100 bases:

>100_bases
AGAAGTAATATATAACAATGTAGATCCTAAGTATAAAGGAAAGCTAAAACTTATTGAACTAAACGAAAAATAAATTTTTT
CGAATCCGTATTTTTATTTT

Downstream 100 bases:

>100_bases
GAGTGTCATTTGCGGATCGTTTATTTCGAATTTTTCCCACGAATAACCGCTAAAAACATCGATTATTTTAAACCCTGCCT
TCTTCATTAAGCTTACTATT

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MKLERVKEPIPLIGHIAFGIIDRGTNVLQVRPFSNCPMSCIFCSVDAGPNSRSRVTEYIVDADHLINWVNYVVDRKIHQV
SILIDGVGEPILHPDIVKIVKGIKENRKVFEVAIETHGLPLNERLIKGLANAGLDRINLSLDSLDENKAKYLSGHKGYNV
SKILKMIDLALNEGLKIMLTPVWIKGMNDEDIINLVKFGKEKGLSFGIQKYVAHPRGRKVGKEVGWKEFKEFLSKIGEML
DVNLFLSPSQFKVFPDVRLGPVMDVGEKVVGEVVLDGWMKNEVIITARGRVITVVGVSDVPKGISLKVKISRNKDEIYLA
RLS

Sequences:

>Translated_323_residues
MKLERVKEPIPLIGHIAFGIIDRGTNVLQVRPFSNCPMSCIFCSVDAGPNSRSRVTEYIVDADHLINWVNYVVDRKIHQV
SILIDGVGEPILHPDIVKIVKGIKENRKVFEVAIETHGLPLNERLIKGLANAGLDRINLSLDSLDENKAKYLSGHKGYNV
SKILKMIDLALNEGLKIMLTPVWIKGMNDEDIINLVKFGKEKGLSFGIQKYVAHPRGRKVGKEVGWKEFKEFLSKIGEML
DVNLFLSPSQFKVFPDVRLGPVMDVGEKVVGEVVLDGWMKNEVIITARGRVITVVGVSDVPKGISLKVKISRNKDEIYLA
RLS
>Mature_323_residues
MKLERVKEPIPLIGHIAFGIIDRGTNVLQVRPFSNCPMSCIFCSVDAGPNSRSRVTEYIVDADHLINWVNYVVDRKIHQV
SILIDGVGEPILHPDIVKIVKGIKENRKVFEVAIETHGLPLNERLIKGLANAGLDRINLSLDSLDENKAKYLSGHKGYNV
SKILKMIDLALNEGLKIMLTPVWIKGMNDEDIINLVKFGKEKGLSFGIQKYVAHPRGRKVGKEVGWKEFKEFLSKIGEML
DVNLFLSPSQFKVFPDVRLGPVMDVGEKVVGEVVLDGWMKNEVIITARGRVITVVGVSDVPKGISLKVKISRNKDEIYLA
RLS

Specific function: Together With Moac, Is Involved In The Conversion Of A Guanosine Derivative (Gxp) Into Molybdopterin Precursor Z. [C]

COG id: COG2100

COG function: function code R; Predicted Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI17561210, Length=235, Percent_Identity=26.8085106382979, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI32566329, Length=209, Percent_Identity=28.2296650717703, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32566331, Length=241, Percent_Identity=26.9709543568465, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 36084; Mature: 36084

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLERVKEPIPLIGHIAFGIIDRGTNVLQVRPFSNCPMSCIFCSVDAGPNSRSRVTEYIV
CCCHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHH
DADHLINWVNYVVDRKIHQVSILIDGVGEPILHPDIVKIVKGIKENRKVFEVAIETHGLP
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCEEEEEEEECCCCC
LNERLIKGLANAGLDRINLSLDSLDENKAKYLSGHKGYNVSKILKMIDLALNEGLKIMLT
HHHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEE
PVWIKGMNDEDIINLVKFGKEKGLSFGIQKYVAHPRGRKVGKEVGWKEFKEFLSKIGEML
EEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHE
DVNLFLSPSQFKVFPDVRLGPVMDVGEKVVGEVVLDGWMKNEVIITARGRVITVVGVSDV
EEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCC
PKGISLKVKISRNKDEIYLARLS
CCCCEEEEEEECCCCEEEEEEEC
>Mature Secondary Structure
MKLERVKEPIPLIGHIAFGIIDRGTNVLQVRPFSNCPMSCIFCSVDAGPNSRSRVTEYIV
CCCHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHH
DADHLINWVNYVVDRKIHQVSILIDGVGEPILHPDIVKIVKGIKENRKVFEVAIETHGLP
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCEEEEEEEECCCCC
LNERLIKGLANAGLDRINLSLDSLDENKAKYLSGHKGYNVSKILKMIDLALNEGLKIMLT
HHHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEE
PVWIKGMNDEDIINLVKFGKEKGLSFGIQKYVAHPRGRKVGKEVGWKEFKEFLSKIGEML
EEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHE
DVNLFLSPSQFKVFPDVRLGPVMDVGEKVVGEVVLDGWMKNEVIITARGRVITVVGVSDV
EEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCC
PKGISLKVKISRNKDEIYLARLS
CCCCEEEEEEECCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]