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The map label for this gene is paaK [H]

Identifier: 15922420

GI number: 15922420

Start: 2103068

End: 2104492

Strand: Direct

Name: paaK [H]

Synonym: ST2095

Alternate gene names: 15922420

Gene position: 2103068-2104492 (Clockwise)

Preceding gene: 15922419

Following gene: 15922422

Centisome position: 78.04

GC content: 35.09

Gene sequence:

>1425_bases
ATGTCTAGTGTTTTAGCTGAATATGAGGCAATCCATAAAGAATTGAGAGAACAAGGTTTTATTAGACCAGATTATCCTCC
AAATCCCTCCGAAATTTTATGGAATAAGAAAATTATGACACTACCAAGAGATGAATTAGACAAAATTAAAACATTTAGGT
TAAAAAGGATAGTAAAATGGGCATGGGAGAATATACCATTCTATAGAAGATTTTGGAAGGAAAAAGGATTTGAACCGGAA
ATGATAAAGGACTGGAAAGATGTAGTAAAGATGCCTATATTAAGAAAAGATGAATTAAGGAAAGATTTACAACAGAACCC
TCCTTTTGGAACTATTTTCCATCCAGAATTAGCAAAAAGAATTAGGTTTGTTGGTGCTACTTCTGGTTCTACTGGACTAC
CTACTTTCCAAGGATGGGGAGCTCTAGAAATGGATTACTTCCAAGAAGGTCAAGCAAGATATTTATGGACTTTTGCTGGA
GTTAAACCAACTGTAGTTTATGCCAATTACTTAAACATGAGTGGTTTCTATAGTTGGGGACCACCAGTAGTTGAAACGGC
AATGTGGAGATGTGGTGCAACAGCAATTGCTGGTGGAGGAGAAACGTTCTTTAGCTGGAAAAATAGGCATATGCTAATCT
TTAAGCTATGGAAAGTTGATGTCTTTGCTACAACTCCGTGGCTACATAGACTTATTGGAGAAGAAGCTAAATTAGAGGGT
TGGGATACACCATTTAAAGTACTATTGCTTCATGGAGGAGCTGCTGCTGAAAATACTAAGAAAAAATTATTTAGTGTTCA
CCCAAATGCAGAATTAGCTATTAACGTATGGGGGACAACAGATGGGCATATGGCTATTGAAGTTCCTGGATCTGAAGGAC
AATTAGTAGTATGGGAGGATATGGAAATCTTTGATATAGTAGATCCAAAAACTGATGAACCAGTAAGTGAAGGTGAAAGA
GGTGAATTAATAGCAACATTATTAAATCATTTTACTATGCCGCTGATACGTTATAGTTTAGGTGATTATGTTAAAAACGA
ATTTATTACTGATCCAGACCCTAAATATGGAATCACACATATGAGATTTGCCGAACCAATACCTGGAAGAGTAGAATGGA
TGTTTAGAGTAAGAGGAAAATTGTTATTCCCGATTTATGTGGAAGATGCTGTAAATGAGATACCAGATACTACTGGAATG
TATAACATAATTGTATATGATAATGAAATGGATAAATTAAAGATTAGGATAGAGACTAGGAAAGAATTTGTAGATCCTCA
GTATGAAAAACAAGCTAAAGAGATTTTAGGAAGTAGATTAGGAATTAACCCAGATGATGTAGAAATAGACTGGGTAAAAC
CTGGACAAACTGTATGGACAGGGTATAAACTTCAAGTATTCTTAGATCAAAGAAAGAAAAAGTAA

Upstream 100 bases:

>100_bases
TTTTAGAAAAAATGATCAAAGAAGGTAAACTAGGAAAGAAGTCTGGAGAAGGGTTCTACAAGTATTAATATTTTTTAAAC
TGTTTATACAATTTAAGCAT

Downstream 100 bases:

>100_bases
CTTAAAAACAAAATTTTTAGCTTTTTAACTCTTTATTTCTTTCCAGATTTTTCTAACATTTGTAGTAATTCTTTTGGTGC
ATCTTTTTCGCTTACAGCGC

Product: phenylacetyl-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MSSVLAEYEAIHKELREQGFIRPDYPPNPSEILWNKKIMTLPRDELDKIKTFRLKRIVKWAWENIPFYRRFWKEKGFEPE
MIKDWKDVVKMPILRKDELRKDLQQNPPFGTIFHPELAKRIRFVGATSGSTGLPTFQGWGALEMDYFQEGQARYLWTFAG
VKPTVVYANYLNMSGFYSWGPPVVETAMWRCGATAIAGGGETFFSWKNRHMLIFKLWKVDVFATTPWLHRLIGEEAKLEG
WDTPFKVLLLHGGAAAENTKKKLFSVHPNAELAINVWGTTDGHMAIEVPGSEGQLVVWEDMEIFDIVDPKTDEPVSEGER
GELIATLLNHFTMPLIRYSLGDYVKNEFITDPDPKYGITHMRFAEPIPGRVEWMFRVRGKLLFPIYVEDAVNEIPDTTGM
YNIIVYDNEMDKLKIRIETRKEFVDPQYEKQAKEILGSRLGINPDDVEIDWVKPGQTVWTGYKLQVFLDQRKKK

Sequences:

>Translated_474_residues
MSSVLAEYEAIHKELREQGFIRPDYPPNPSEILWNKKIMTLPRDELDKIKTFRLKRIVKWAWENIPFYRRFWKEKGFEPE
MIKDWKDVVKMPILRKDELRKDLQQNPPFGTIFHPELAKRIRFVGATSGSTGLPTFQGWGALEMDYFQEGQARYLWTFAG
VKPTVVYANYLNMSGFYSWGPPVVETAMWRCGATAIAGGGETFFSWKNRHMLIFKLWKVDVFATTPWLHRLIGEEAKLEG
WDTPFKVLLLHGGAAAENTKKKLFSVHPNAELAINVWGTTDGHMAIEVPGSEGQLVVWEDMEIFDIVDPKTDEPVSEGER
GELIATLLNHFTMPLIRYSLGDYVKNEFITDPDPKYGITHMRFAEPIPGRVEWMFRVRGKLLFPIYVEDAVNEIPDTTGM
YNIIVYDNEMDKLKIRIETRKEFVDPQYEKQAKEILGSRLGINPDDVEIDWVKPGQTVWTGYKLQVFLDQRKKK
>Mature_473_residues
SSVLAEYEAIHKELREQGFIRPDYPPNPSEILWNKKIMTLPRDELDKIKTFRLKRIVKWAWENIPFYRRFWKEKGFEPEM
IKDWKDVVKMPILRKDELRKDLQQNPPFGTIFHPELAKRIRFVGATSGSTGLPTFQGWGALEMDYFQEGQARYLWTFAGV
KPTVVYANYLNMSGFYSWGPPVVETAMWRCGATAIAGGGETFFSWKNRHMLIFKLWKVDVFATTPWLHRLIGEEAKLEGW
DTPFKVLLLHGGAAAENTKKKLFSVHPNAELAINVWGTTDGHMAIEVPGSEGQLVVWEDMEIFDIVDPKTDEPVSEGERG
ELIATLLNHFTMPLIRYSLGDYVKNEFITDPDPKYGITHMRFAEPIPGRVEWMFRVRGKLLFPIYVEDAVNEIPDTTGMY
NIIVYDNEMDKLKIRIETRKEFVDPQYEKQAKEILGSRLGINPDDVEIDWVKPGQTVWTGYKLQVFLDQRKKK

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=421, Percent_Identity=26.8408551068884, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 55051; Mature: 54920

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVLAEYEAIHKELREQGFIRPDYPPNPSEILWNKKIMTLPRDELDKIKTFRLKRIVKW
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEECCEEEECCHHHHHHHHHHHHHHHHHH
AWENIPFYRRFWKEKGFEPEMIKDWKDVVKMPILRKDELRKDLQQNPPFGTIFHPELAKR
HHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEECHHHHHH
IRFVGATSGSTGLPTFQGWGALEMDYFQEGQARYLWTFAGVKPTVVYANYLNMSGFYSWG
EEEEECCCCCCCCCCCCCCCCEEHHHHHCCCCEEEEEECCCCEEEEEEEECCCCCCCCCC
PPVVETAMWRCGATAIAGGGETFFSWKNRHMLIFKLWKVDVFATTPWLHRLIGEEAKLEG
CHHHHHHHHHCCCEEECCCCCEEEEECCCEEEEEEEEEEEEEECCHHHHHHHCCCCCCCC
WDTPFKVLLLHGGAAAENTKKKLFSVHPNAELAINVWGTTDGHMAIEVPGSEGQLVVWED
CCCCEEEEEEECCCCCCCHHHHEEEECCCCEEEEEEECCCCCEEEEEECCCCCCEEEEEC
MEIFDIVDPKTDEPVSEGERGELIATLLNHFTMPLIRYSLGDYVKNEFITDPDPKYGITH
CEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
MRFAEPIPGRVEWMFRVRGKLLFPIYVEDAVNEIPDTTGMYNIIVYDNEMDKLKIRIETR
EEECCCCCCHHHHHEEECCCEEEEEEEHHHHHHCCCCCCEEEEEEEECCCCEEEEEEEEH
KEFVDPQYEKQAKEILGSRLGINPDDVEIDWVKPGQTVWTGYKLQVFLDQRKKK
HHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEECCEEEEEEEECCCCC
>Mature Secondary Structure 
SSVLAEYEAIHKELREQGFIRPDYPPNPSEILWNKKIMTLPRDELDKIKTFRLKRIVKW
CHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEECCEEEECCHHHHHHHHHHHHHHHHHH
AWENIPFYRRFWKEKGFEPEMIKDWKDVVKMPILRKDELRKDLQQNPPFGTIFHPELAKR
HHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEECHHHHHH
IRFVGATSGSTGLPTFQGWGALEMDYFQEGQARYLWTFAGVKPTVVYANYLNMSGFYSWG
EEEEECCCCCCCCCCCCCCCCEEHHHHHCCCCEEEEEECCCCEEEEEEEECCCCCCCCCC
PPVVETAMWRCGATAIAGGGETFFSWKNRHMLIFKLWKVDVFATTPWLHRLIGEEAKLEG
CHHHHHHHHHCCCEEECCCCCEEEEECCCEEEEEEEEEEEEEECCHHHHHHHCCCCCCCC
WDTPFKVLLLHGGAAAENTKKKLFSVHPNAELAINVWGTTDGHMAIEVPGSEGQLVVWED
CCCCEEEEEEECCCCCCCHHHHEEEECCCCEEEEEEECCCCCEEEEEECCCCCCEEEEEC
MEIFDIVDPKTDEPVSEGERGELIATLLNHFTMPLIRYSLGDYVKNEFITDPDPKYGITH
CEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
MRFAEPIPGRVEWMFRVRGKLLFPIYVEDAVNEIPDTTGMYNIIVYDNEMDKLKIRIETR
EEECCCCCCHHHHHEEECCCEEEEEEEHHHHHHCCCCCCEEEEEEEECCCCEEEEEEEEH
KEFVDPQYEKQAKEILGSRLGINPDDVEIDWVKPGQTVWTGYKLQVFLDQRKKK
HHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEECCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]