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The map label for this gene is mtaD [H]

Identifier: 15922367

GI number: 15922367

Start: 2057654

End: 2058889

Strand: Direct

Name: mtaD [H]

Synonym: ST2049

Alternate gene names: 15922367

Gene position: 2057654-2058889 (Clockwise)

Preceding gene: 15922366

Following gene: 15922369

Centisome position: 76.36

GC content: 30.18

Gene sequence:

>1236_bases
GTGGAGATTTATCATCACACATATACATTAAAAAATTGTAGTTTTATTGTAAATTATGATTCTATCATAGAAAACAGCAA
TATTGTAATTGAAGACGGAATTATTAAAAATTTAGGAAAAGAAGTTGAAGGAGATGAAATCGATTGTAGTAACTTTATAG
TTATTCCCGGATTGGTAAATGCACACACTCATACGCCAATGATTATATTAAGGGGGTATTATGATGATGCAGAATTAAGT
GAATGGTTAAATAAAATGTGGGAGTTTGAGAAAAATTTTGACAAAAAACTAATGAGATTAGGTTCTGAAATTTCCATACT
CGAGATGCTAATTAATGGAACTACAGCGTTTGTAGACATGTATTTTAATCCTTTAGATGTTAAAGAATTAGCAGAAATAT
ACAAAATAAGAGCTTTTGCTGGATTCACATTTCTTGACTCATTAAATGATCCCTATTTTATTGATAAACTCCAAAGAACT
TTAACTCCTACAACATATTTTAAACCTATAATAAATGTACATAGTGTATATACCGTAAGTGAAAGTACATTAAAGTTAGC
AAAACAATTACAAGAAGAATTAAATGAATGGGTTCATATTCATGTATCTGAAACTAGAAAAGAAATATATGAAATAAAAA
AGAAATATGGCGTATTCCCAATAGAGTATTTAAACAACCTAGGACTGTTAAACAGAAAAATTCAATTAGTTCATGTAGGC
TGGATAGCCAGTTGGGAAATTGACCTACTTAAAAACACCACAGTGACATATTGCCCTACATCTAACATGAAATTAGCAAC
AGGCGGTGCATTCCCATTGTATGATATGTTTAATAAAGGGGTAAATATAACACTAGGAACTGACGGACCTGCAAGTAATA
ATTCTTTAGATTTATTCATAGAAATGAAATACGGAGTTCTGCTTCAAAGACAAATGTATTGGAATACTGACGTTAAAGCA
TGGCATTTATTTAAAATAGCTACCTTAAATGGCTACAAACTCTTAGATCTACCAGGCGGATACATAAAAGAAGGAAATAT
AGCTGATCTTGTCTTATTGGATAAAAACAAAATATATCCACTTTTTAGAGATAGACTATTATCACACTTAGTATATTACG
CCACTGGGAGTCTTGCTAAAGGCATAATAATAAACGGAGTATTAAGATGGAGAAAAGAACTAGAAAATCTTCTATTAGAA
AAAACTAAACAGATTTATGAACTACTAAACTCTTGA

Upstream 100 bases:

>100_bases
CATTTGAAGGAGGAGAAGCTGAAACTTTTGTGGTTTACGCACCATTGTTCAAAAGAGAATTAAAGATTGAAGGTTATAAA
AAGAAAATAAGTGAATATGA

Downstream 100 bases:

>100_bases
TCTACTAGCTGAGCCATCTTTTCAGCACAATCTTTAATATCACTTAGAATTTTCTGTTTCAATTCATTATAATCTTTTGT
TTTATAAAGATATCTTGGCC

Product: hypothetical protein

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MEIYHHTYTLKNCSFIVNYDSIIENSNIVIEDGIIKNLGKEVEGDEIDCSNFIVIPGLVNAHTHTPMIILRGYYDDAELS
EWLNKMWEFEKNFDKKLMRLGSEISILEMLINGTTAFVDMYFNPLDVKELAEIYKIRAFAGFTFLDSLNDPYFIDKLQRT
LTPTTYFKPIINVHSVYTVSESTLKLAKQLQEELNEWVHIHVSETRKEIYEIKKKYGVFPIEYLNNLGLLNRKIQLVHVG
WIASWEIDLLKNTTVTYCPTSNMKLATGGAFPLYDMFNKGVNITLGTDGPASNNSLDLFIEMKYGVLLQRQMYWNTDVKA
WHLFKIATLNGYKLLDLPGGYIKEGNIADLVLLDKNKIYPLFRDRLLSHLVYYATGSLAKGIIINGVLRWRKELENLLLE
KTKQIYELLNS

Sequences:

>Translated_411_residues
MEIYHHTYTLKNCSFIVNYDSIIENSNIVIEDGIIKNLGKEVEGDEIDCSNFIVIPGLVNAHTHTPMIILRGYYDDAELS
EWLNKMWEFEKNFDKKLMRLGSEISILEMLINGTTAFVDMYFNPLDVKELAEIYKIRAFAGFTFLDSLNDPYFIDKLQRT
LTPTTYFKPIINVHSVYTVSESTLKLAKQLQEELNEWVHIHVSETRKEIYEIKKKYGVFPIEYLNNLGLLNRKIQLVHVG
WIASWEIDLLKNTTVTYCPTSNMKLATGGAFPLYDMFNKGVNITLGTDGPASNNSLDLFIEMKYGVLLQRQMYWNTDVKA
WHLFKIATLNGYKLLDLPGGYIKEGNIADLVLLDKNKIYPLFRDRLLSHLVYYATGSLAKGIIINGVLRWRKELENLLLE
KTKQIYELLNS
>Mature_411_residues
MEIYHHTYTLKNCSFIVNYDSIIENSNIVIEDGIIKNLGKEVEGDEIDCSNFIVIPGLVNAHTHTPMIILRGYYDDAELS
EWLNKMWEFEKNFDKKLMRLGSEISILEMLINGTTAFVDMYFNPLDVKELAEIYKIRAFAGFTFLDSLNDPYFIDKLQRT
LTPTTYFKPIINVHSVYTVSESTLKLAKQLQEELNEWVHIHVSETRKEIYEIKKKYGVFPIEYLNNLGLLNRKIQLVHVG
WIASWEIDLLKNTTVTYCPTSNMKLATGGAFPLYDMFNKGVNITLGTDGPASNNSLDLFIEMKYGVLLQRQMYWNTDVKA
WHLFKIATLNGYKLLDLPGGYIKEGNIADLVLLDKNKIYPLFRDRLLSHLVYYATGSLAKGIIINGVLRWRKELENLLLE
KTKQIYELLNS

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Escherichia coli, GI1789249, Length=381, Percent_Identity=28.0839895013123, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87082177, Length=418, Percent_Identity=22.7272727272727, Blast_Score=90, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319963, Length=381, Percent_Identity=22.0472440944882, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24643849, Length=384, Percent_Identity=25, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 47503; Mature: 47503

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIYHHTYTLKNCSFIVNYDSIIENSNIVIEDGIIKNLGKEVEGDEIDCSNFIVIPGLVN
CEEEEEEEEECCCEEEEEHHHHHCCCCEEEECCHHHHCCCCCCCCCCCCCCEEEECCEEC
AHTHTPMIILRGYYDDAELSEWLNKMWEFEKNFDKKLMRLGSEISILEMLINGTTAFVDM
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEE
YFNPLDVKELAEIYKIRAFAGFTFLDSLNDPYFIDKLQRTLTPTTYFKPIINVHSVYTVS
ECCCCCHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHEEEEEC
ESTLKLAKQLQEELNEWVHIHVSETRKEIYEIKKKYGVFPIEYLNNLGLLNRKIQLVHVG
HHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEEEEE
WIASWEIDLLKNTTVTYCPTSNMKLATGGAFPLYDMFNKGVNITLGTDGPASNNSLDLFI
EEEEEEEEEEECCEEEEECCCCEEEECCCCCHHHHHHHCCEEEEECCCCCCCCCCEEEEE
EMKYGVLLQRQMYWNTDVKAWHLFKIATLNGYKLLDLPGGYIKEGNIADLVLLDKNKIYP
EEECCEEEEHHHHCCCCCCEEEEEEEEEECCEEEEECCCCCCCCCCEEEEEEECCCCCCH
LFRDRLLSHLVYYATGSLAKGIIINGVLRWRKELENLLLEKTKQIYELLNS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIYHHTYTLKNCSFIVNYDSIIENSNIVIEDGIIKNLGKEVEGDEIDCSNFIVIPGLVN
CEEEEEEEEECCCEEEEEHHHHHCCCCEEEECCHHHHCCCCCCCCCCCCCCEEEECCEEC
AHTHTPMIILRGYYDDAELSEWLNKMWEFEKNFDKKLMRLGSEISILEMLINGTTAFVDM
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEE
YFNPLDVKELAEIYKIRAFAGFTFLDSLNDPYFIDKLQRTLTPTTYFKPIINVHSVYTVS
ECCCCCHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHEEEEEC
ESTLKLAKQLQEELNEWVHIHVSETRKEIYEIKKKYGVFPIEYLNNLGLLNRKIQLVHVG
HHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEEEEE
WIASWEIDLLKNTTVTYCPTSNMKLATGGAFPLYDMFNKGVNITLGTDGPASNNSLDLFI
EEEEEEEEEEECCEEEEECCCCEEEECCCCCHHHHHHHCCEEEEECCCCCCCCCCEEEEE
EMKYGVLLQRQMYWNTDVKAWHLFKIATLNGYKLLDLPGGYIKEGNIADLVLLDKNKIYP
EEECCEEEEHHHHCCCCCCEEEEEEEEEECCEEEEECCCCCCCCCCEEEEEEECCCCCCH
LFRDRLLSHLVYYATGSLAKGIIINGVLRWRKELENLLLEKTKQIYELLNS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA