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The map label for this gene is acuC [H]

Identifier: 15922198

GI number: 15922198

Start: 1893111

End: 1894109

Strand: Reverse

Name: acuC [H]

Synonym: ST1884

Alternate gene names: 15922198

Gene position: 1894109-1893111 (Counterclockwise)

Preceding gene: 15922199

Following gene: 15922196

Centisome position: 70.29

GC content: 34.33

Gene sequence:

>999_bases
ATGCTGGGTATTGTATGGGATGATAAATTTAAAGAAATAGCATTTTCCCATCCAATGATTAAGGATATAGCAAAAGAAAG
GATTAGAAGATTCATAGAAATAGCAAGGCAAAAGCTTAATTTTATTGAAATAAAGCCAGAAAAAGCTACAATAGACGATC
TTTTAAAGATACATGACGAGAGCTACGTTAAGAAAATTGAAGAAGTAAGCAAGTTACCCTATATTGGTTTTCTTGACGGT
GGGGATACAATTCATTATCCGGGAATGATAGATGATGTATTGTTAGTCTTAGGAGCATCAATTACTGCAATAAAATACTC
TAGATTTATTGAAAAAATTTATATACCATTAGGTGGATTTCATCACGCGTTACGGCAAAGGGCTATGGGATTTTGTCCAA
TCAATGATGTCGCATTTACCGCATTAGCTTTGCTCGAAAAAGGTGAAAGAGTTGCTATAATTGATGTTGATGCTCATCAT
GGTAATGGTTTACAAGAGTATCTTTACGACAAGTCAATTCTTAAAATAAATATTTTTGCGTATGACGGTAAATTTTTCCC
TGGAACGGGGAAAATAGAAGAAAGAGGTATTGGTGATGGTAAGGGGTTAAACTATAACGTTCAGCTTCCTTTATATTCTG
GCGATGATGTTTTTGAGGAGGCTTTGCGAATTTTAGAGATTGTACCAGATTTTAATCCGACTTATATACTCATAGTTGGT
GGAGTGGACGGACATAAGGATGATGGTTTAAAATCCCTTAATTTATCTTGTAACTCTTATAATCTTCTCGGTTTAAAGGT
TAGAAGGATTTCCTTAAACTCTAAGGTAATTGGATATGGAGGTGGGGGGTATGGGAAAATGTCGTCTGAATGTATGGTTT
CCTTCTTACTTGGTCTTGAAGGGAAAAGAGAAGAGATAGAGGCAAAAACTTTTTCAGAAAAAGAAAAAATTGAAAAAGTT
AAAAACGAGATTAACTTATTGCTTCAAGGCTTTTCCTAA

Upstream 100 bases:

>100_bases
TTAGGTTATAATACTCCTCCAATGATAAGAGTATTTAGGAAACCAATTTTCAAAGAGGGGGAAGAGATTAAACTTGAAGA
CTTAAAGAAGATGATCTGAA

Downstream 100 bases:

>100_bases
ATCCTCAGCAAACTTTACTAATGCACCTATTGCATAGCTTGTATCCTTATTTCCTAAAGCTCCTACTAATCCAAATGTGC
TTACTGGTTTAACACTAGGC

Product: acetoin utilization protein AcuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MLGIVWDDKFKEIAFSHPMIKDIAKERIRRFIEIARQKLNFIEIKPEKATIDDLLKIHDESYVKKIEEVSKLPYIGFLDG
GDTIHYPGMIDDVLLVLGASITAIKYSRFIEKIYIPLGGFHHALRQRAMGFCPINDVAFTALALLEKGERVAIIDVDAHH
GNGLQEYLYDKSILKINIFAYDGKFFPGTGKIEERGIGDGKGLNYNVQLPLYSGDDVFEEALRILEIVPDFNPTYILIVG
GVDGHKDDGLKSLNLSCNSYNLLGLKVRRISLNSKVIGYGGGGYGKMSSECMVSFLLGLEGKREEIEAKTFSEKEKIEKV
KNEINLLLQGFS

Sequences:

>Translated_332_residues
MLGIVWDDKFKEIAFSHPMIKDIAKERIRRFIEIARQKLNFIEIKPEKATIDDLLKIHDESYVKKIEEVSKLPYIGFLDG
GDTIHYPGMIDDVLLVLGASITAIKYSRFIEKIYIPLGGFHHALRQRAMGFCPINDVAFTALALLEKGERVAIIDVDAHH
GNGLQEYLYDKSILKINIFAYDGKFFPGTGKIEERGIGDGKGLNYNVQLPLYSGDDVFEEALRILEIVPDFNPTYILIVG
GVDGHKDDGLKSLNLSCNSYNLLGLKVRRISLNSKVIGYGGGGYGKMSSECMVSFLLGLEGKREEIEAKTFSEKEKIEKV
KNEINLLLQGFS
>Mature_332_residues
MLGIVWDDKFKEIAFSHPMIKDIAKERIRRFIEIARQKLNFIEIKPEKATIDDLLKIHDESYVKKIEEVSKLPYIGFLDG
GDTIHYPGMIDDVLLVLGASITAIKYSRFIEKIYIPLGGFHHALRQRAMGFCPINDVAFTALALLEKGERVAIIDVDAHH
GNGLQEYLYDKSILKINIFAYDGKFFPGTGKIEERGIGDGKGLNYNVQLPLYSGDDVFEEALRILEIVPDFNPTYILIVG
GVDGHKDDGLKSLNLSCNSYNLLGLKVRRISLNSKVIGYGGGGYGKMSSECMVSFLLGLEGKREEIEAKTFSEKEKIEKV
KNEINLLLQGFS

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128862, Length=290, Percent_Identity=32.0689655172414, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI13128860, Length=254, Percent_Identity=31.8897637795276, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI293336691, Length=226, Percent_Identity=31.858407079646, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI8923769, Length=272, Percent_Identity=27.5735294117647, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI169234807, Length=218, Percent_Identity=31.1926605504587, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI148539870, Length=218, Percent_Identity=31.1926605504587, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI262073092, Length=185, Percent_Identity=31.3513513513514, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI17158039, Length=138, Percent_Identity=41.304347826087, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI30795202, Length=138, Percent_Identity=41.304347826087, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI30795204, Length=138, Percent_Identity=41.304347826087, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI153085395, Length=201, Percent_Identity=36.318407960199, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI262073088, Length=186, Percent_Identity=27.4193548387097, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI62750349, Length=140, Percent_Identity=42.8571428571429, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI62750347, Length=140, Percent_Identity=42.8571428571429, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI20070354, Length=319, Percent_Identity=26.0188087774295, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI13128864, Length=276, Percent_Identity=28.2608695652174, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI226529806, Length=222, Percent_Identity=27.4774774774775, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17508561, Length=272, Percent_Identity=31.6176470588235, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17561978, Length=254, Percent_Identity=29.5275590551181, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17534739, Length=258, Percent_Identity=31.7829457364341, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193209491, Length=243, Percent_Identity=30.8641975308642, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193206283, Length=237, Percent_Identity=28.6919831223629, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17540334, Length=177, Percent_Identity=31.638418079096, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17540332, Length=237, Percent_Identity=28.6919831223629, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321244, Length=267, Percent_Identity=32.2097378277154, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6323999, Length=278, Percent_Identity=29.4964028776978, Blast_Score=102, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6324307, Length=260, Percent_Identity=26.1538461538462, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6325325, Length=192, Percent_Identity=30.2083333333333, Blast_Score=79, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24657891, Length=264, Percent_Identity=32.5757575757576, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24644244, Length=259, Percent_Identity=33.2046332046332, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24642146, Length=249, Percent_Identity=28.9156626506024, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24642144, Length=249, Percent_Identity=28.9156626506024, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24642142, Length=249, Percent_Identity=28.9156626506024, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI281360899, Length=251, Percent_Identity=28.6852589641434, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24641720, Length=180, Percent_Identity=35.5555555555556, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281360801, Length=180, Percent_Identity=35.5555555555556, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281360799, Length=180, Percent_Identity=35.5555555555556, Blast_Score=85, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 37256; Mature: 37256

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGIVWDDKFKEIAFSHPMIKDIAKERIRRFIEIARQKLNFIEIKPEKATIDDLLKIHDE
CCEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCH
SYVKKIEEVSKLPYIGFLDGGDTIHYPGMIDDVLLVLGASITAIKYSRFIEKIYIPLGGF
HHHHHHHHHHHCCEEEEECCCCEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHH
HHALRQRAMGFCPINDVAFTALALLEKGERVAIIDVDAHHGNGLQEYLYDKSILKINIFA
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHCCCCEEEEEEEE
YDGKFFPGTGKIEERGIGDGKGLNYNVQLPLYSGDDVFEEALRILEIVPDFNPTYILIVG
ECCEECCCCCCHHHCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEE
GVDGHKDDGLKSLNLSCNSYNLLGLKVRRISLNSKVIGYGGGGYGKMSSECMVSFLLGLE
CCCCCCCCCCEEEECCCCCEEEEEEEEEEEEECCEEEEECCCCCCCCHHHHHHHHHHCCC
GKREEIEAKTFSEKEKIEKVKNEINLLLQGFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MLGIVWDDKFKEIAFSHPMIKDIAKERIRRFIEIARQKLNFIEIKPEKATIDDLLKIHDE
CCEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHCCH
SYVKKIEEVSKLPYIGFLDGGDTIHYPGMIDDVLLVLGASITAIKYSRFIEKIYIPLGGF
HHHHHHHHHHHCCEEEEECCCCEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHH
HHALRQRAMGFCPINDVAFTALALLEKGERVAIIDVDAHHGNGLQEYLYDKSILKINIFA
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHCCCCEEEEEEEE
YDGKFFPGTGKIEERGIGDGKGLNYNVQLPLYSGDDVFEEALRILEIVPDFNPTYILIVG
ECCEECCCCCCHHHCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEE
GVDGHKDDGLKSLNLSCNSYNLLGLKVRRISLNSKVIGYGGGGYGKMSSECMVSFLLGLE
CCCCCCCCCCEEEECCCCCEEEEEEEEEEEEECCEEEEECCCCCCCCHHHHHHHHHHCCC
GKREEIEAKTFSEKEKIEKVKNEINLLLQGFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]