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The map label for this gene is hdrA [H]

Identifier: 15922186

GI number: 15922186

Start: 1884403

End: 1885500

Strand: Reverse

Name: hdrA [H]

Synonym: ST1873

Alternate gene names: 15922186

Gene position: 1885500-1884403 (Counterclockwise)

Preceding gene: 15922187

Following gene: 15922185

Centisome position: 69.97

GC content: 35.79

Gene sequence:

>1098_bases
ATGGCTGGTGAAAAAGTTCTCGTAATTGGAGCTGGGCCCGCTGGATTATCTGCTACAAAGGAATTGGCTAATTTAGGTGT
TAACGTAGTTTTAGTAGAGAGAGAAGCTTTTCTTGGTGGTACTCCAAAAAGATTGAAATATAGCCTATTATTCCCAGAAT
TAAGGCCTGCCTCAGAAGTAATTGATCCTCTAATTAAATCAGTCCAGGAAAATAAAAATGTTAAAATTTACCTAGAAAGT
ATAGTTGATAGTGTAAAACAAGAGGGTAATGGATTTACTGTGAATATTAAGGATAAGAGCGGAAAAATTACTACAGAAAA
AGTAAATGCAATTATAGCTGCTTCAGGTTTTGAACATTTTGATTCTAGGAGAAAATATGAGTATGGTTATGGGATAATAC
CAAACATTTATCAAATCTCTGATATTGAAGGTATGCTTTCAGAAAATAGATTAGTAACTACAAAGGGTACACCACCAAAA
AGAGTTGCAATCTTATTATGTGTTGGTTCAAGAGACGCCACTGTAGGAAATACTTATTGTTCAAGAGTCTGTTGTGCCGT
ATCAATTAAGCAAGCAATGGAAATTAAGCAAAGGATTCCAGATGCGGTTGTTCATATTTACTATATGGATATAAGAACTT
ATGGATTAATGGAGGATAAACTATACTGGAAAGCACAATTAGACTACAGAGTGGGATTCATAAGAGGAAGAATTTCAGAA
TTCATGAGAGGCCCCAATGACACGGTGATAATTAAAGGAGAAGATACAATGAACTTGAATAGAGCATTAGTAGTTCCATA
TGATATGGTAATATTAGCTAACGGTATGGAACTAGGTTTAGGTTCAAAACAAGTAGCTAAAGTTTTAGGACTAGAGTTTG
AAAGCCACGGATTTGTCAAACCATTAGATCCAGATAGGTTACCAGTTCAATCAACTAAGAAAGGAATATTCCTAGCTGGT
GCAATAACTGGTCCTAAGACAATATCAGACTCAATAACAGAAGGATATGCTGCTGCAATGAAGGCTTATGAGTATATTAT
GAAGGGCACATGGGAGGAACCAGTAAAGGTAGCTACTGCTGAGGTGGCTCATCATTAA

Upstream 100 bases:

>100_bases
AGACAGAGTAAAATGGTATAAAGGTGAGCAAGCTGTTCAAAAGTGAAAAGCAAAGTTTTTTAAATTATTTTTATTTAATT
AATATGTAGTTGGTGAAAAA

Downstream 100 bases:

>100_bases
CATGATTTTTTTAAATGTTGATTATGTAAAAGATATTTTTAATGCTATGTTAGATAAGGATATAAATAATACTGTATCTG
ATCCGAAAAAATCCTTATCT

Product: heterodisulfide reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MAGEKVLVIGAGPAGLSATKELANLGVNVVLVEREAFLGGTPKRLKYSLLFPELRPASEVIDPLIKSVQENKNVKIYLES
IVDSVKQEGNGFTVNIKDKSGKITTEKVNAIIAASGFEHFDSRRKYEYGYGIIPNIYQISDIEGMLSENRLVTTKGTPPK
RVAILLCVGSRDATVGNTYCSRVCCAVSIKQAMEIKQRIPDAVVHIYYMDIRTYGLMEDKLYWKAQLDYRVGFIRGRISE
FMRGPNDTVIIKGEDTMNLNRALVVPYDMVILANGMELGLGSKQVAKVLGLEFESHGFVKPLDPDRLPVQSTKKGIFLAG
AITGPKTISDSITEGYAAAMKAYEYIMKGTWEEPVKVATAEVAHH

Sequences:

>Translated_365_residues
MAGEKVLVIGAGPAGLSATKELANLGVNVVLVEREAFLGGTPKRLKYSLLFPELRPASEVIDPLIKSVQENKNVKIYLES
IVDSVKQEGNGFTVNIKDKSGKITTEKVNAIIAASGFEHFDSRRKYEYGYGIIPNIYQISDIEGMLSENRLVTTKGTPPK
RVAILLCVGSRDATVGNTYCSRVCCAVSIKQAMEIKQRIPDAVVHIYYMDIRTYGLMEDKLYWKAQLDYRVGFIRGRISE
FMRGPNDTVIIKGEDTMNLNRALVVPYDMVILANGMELGLGSKQVAKVLGLEFESHGFVKPLDPDRLPVQSTKKGIFLAG
AITGPKTISDSITEGYAAAMKAYEYIMKGTWEEPVKVATAEVAHH
>Mature_364_residues
AGEKVLVIGAGPAGLSATKELANLGVNVVLVEREAFLGGTPKRLKYSLLFPELRPASEVIDPLIKSVQENKNVKIYLESI
VDSVKQEGNGFTVNIKDKSGKITTEKVNAIIAASGFEHFDSRRKYEYGYGIIPNIYQISDIEGMLSENRLVTTKGTPPKR
VAILLCVGSRDATVGNTYCSRVCCAVSIKQAMEIKQRIPDAVVHIYYMDIRTYGLMEDKLYWKAQLDYRVGFIRGRISEF
MRGPNDTVIIKGEDTMNLNRALVVPYDMVILANGMELGLGSKQVAKVLGLEFESHGFVKPLDPDRLPVQSTKKGIFLAGA
ITGPKTISDSITEGYAAAMKAYEYIMKGTWEEPVKVATAEVAHH

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). May act as the catalytic subunit [H]

COG id: COG1148

COG function: function code C; Heterodisulfide reductase, subunit A and related polyferredoxins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003953 [H]

Pfam domain/function: PF00890 FAD_binding_2 [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 40188; Mature: 40057

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGEKVLVIGAGPAGLSATKELANLGVNVVLVEREAFLGGTPKRLKYSLLFPELRPASEV
CCCCEEEEEECCCCCCHHHHHHHHCCCEEEEEEEHHHCCCCHHHEEEEEECCCCCCHHHH
IDPLIKSVQENKNVKIYLESIVDSVKQEGNGFTVNIKDKSGKITTEKVNAIIAASGFEHF
HHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCEEEEEECCCCCEEHHHHEEEEEECCCHHH
DSRRKYEYGYGIIPNIYQISDIEGMLSENRLVTTKGTPPKRVAILLCVGSRDATVGNTYC
HCCCCEECCCCCCCCCEEECCHHHHHCCCEEEEECCCCCCEEEEEEEECCCCCCCCHHHH
SRVCCAVSIKQAMEIKQRIPDAVVHIYYMDIRTYGLMEDKLYWKAQLDYRVGFIRGRISE
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCEEEEEEECEEEEHHHHHHHH
FMRGPNDTVIIKGEDTMNLNRALVVPYDMVILANGMELGLGSKQVAKVLGLEFESHGFVK
HHCCCCCEEEEECCCCCCCCEEEECCEEEEEEECCCEECCCHHHHHHHHCCEECCCCCCC
PLDPDRLPVQSTKKGIFLAGAITGPKTISDSITEGYAAAMKAYEYIMKGTWEEPVKVATA
CCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
EVAHH
HHCCC
>Mature Secondary Structure 
AGEKVLVIGAGPAGLSATKELANLGVNVVLVEREAFLGGTPKRLKYSLLFPELRPASEV
CCCEEEEEECCCCCCHHHHHHHHCCCEEEEEEEHHHCCCCHHHEEEEEECCCCCCHHHH
IDPLIKSVQENKNVKIYLESIVDSVKQEGNGFTVNIKDKSGKITTEKVNAIIAASGFEHF
HHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCEEEEEECCCCCEEHHHHEEEEEECCCHHH
DSRRKYEYGYGIIPNIYQISDIEGMLSENRLVTTKGTPPKRVAILLCVGSRDATVGNTYC
HCCCCEECCCCCCCCCEEECCHHHHHCCCEEEEECCCCCCEEEEEEEECCCCCCCCHHHH
SRVCCAVSIKQAMEIKQRIPDAVVHIYYMDIRTYGLMEDKLYWKAQLDYRVGFIRGRISE
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCEEEEEEECEEEEHHHHHHHH
FMRGPNDTVIIKGEDTMNLNRALVVPYDMVILANGMELGLGSKQVAKVLGLEFESHGFVK
HHCCCCCEEEEECCCCCCCCEEEECCEEEEEEECCCEECCCHHHHHHHHCCEECCCCCCC
PLDPDRLPVQSTKKGIFLAGAITGPKTISDSITEGYAAAMKAYEYIMKGTWEEPVKVATA
CCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
EVAHH
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]