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The map label for this gene is fixC [H]

Identifier: 15922108

GI number: 15922108

Start: 1811978

End: 1813198

Strand: Direct

Name: fixC [H]

Synonym: ST1795

Alternate gene names: 15922108

Gene position: 1811978-1813198 (Clockwise)

Preceding gene: 15922107

Following gene: 15922109

Centisome position: 67.24

GC content: 35.05

Gene sequence:

>1221_bases
GTGAGTTTTGATGCTGACGTGATAATTGTAGGGGGAGGATTATCTGGGTTATCTGCCGGAATAACTGCAGTAAAAGAGGG
TTTGAACGTTATACTTTTAGAGAGAGGGGAATATAGCGGTGCTAAAAATGTATCTGGAGGAAGAATGTATATCCATGCTC
TTCAAAAATTGATACCAGATGCTTTAGAAAGAGCTCCTCTTGAAAGACCTATCACAAAGGAGACTTATGAATTTTATTGT
AAAAATAAAAAGCTAATATTCTCCTTCGAGGAAAAAGGTAAGAAAAATAGTTATAGTGTGTTAAGAGCTAAATTTGATAG
ATGGCTAGCTAGTGAAGCAGAAAGTTTAGGTTTACTAATATCTTATTCAACATTGGTTACAAATGCATATAGAGAGAATG
GTGGAATTACGTTGGAAACTAATAGGGGTACCTTAAGAGCACCATTAGTAATTGACGCTTCTGGAGTAACATCGGTAGTA
TTTAGATATTTAGGTTTAAGAAACTTTACTCCAGATAAATGGATGCTAGGAGTGAAAGAGATAGTTAAAGCCAACGTAAG
CCTATCAGAAGATGAGGGAGAAGCTAGGACAATTGTAGGTTTAATTAACGGAGTAAAAGGAGGGGGATTCGTTTACACAA
ACAAGGATACTTTATCTGTTGGTATGGCTGTAACTTTTGATTCCTTACCAAAATCAGAAGTGCCAGCAAAAGATCTGGTA
GAGAATTTCAGGGAAAAACTTGGTATTGAGGGGGAGATTCTCGAATATTCTGCCCATGCAATACCCTACTACGGTTTTAA
GAATTTACAACAGCTTTATGCTGATAATTTAATTGCGGTTGGTGATTCTGCTGGATTTTTAATAAATGATGGGTTTACAA
TAAGAGGAATGGACTTAGCAATAGCATCTGGAATGATAGCTGGGTTAGTAGCTAAAAAAATCGTGGAAATGAAAGACTTC
ACAAAGACGAATATATATTACGATATGTTAAAAGAAAGTTTTGTACTTAAACATCTAGAGTTGGCTTATAGTAGATTCGA
GTTGATAAATAGGGGAACAACTCTTAACAATTACACCGAGATACTTTGCGATTTACTATCAGATATGTTTACAGTTACTG
AAGATAGAAAGACCTTAATAGAGTATGCTTTGCTAAAATTAAAAGAGAAAGGAATAAGTTTAACCCAAGCAATAAGAGAT
ATGGTAAGTGCTGTAAAATGA

Upstream 100 bases:

>100_bases
ATAAAGATAAATCAGCGCCTATTGTTGAAAATGCTGATTATATCATCATAGGTGATGCTATAGAGTTTTGCCAGGTCATG
ACTGAAAAGGTGAAGAAAAA

Downstream 100 bases:

>100_bases
TACCCCTACTTAAAAGATTAGGATTAAATAAATACTCAGTAGATCCAAAACCACACATAGAAGTTAATACTGACATATGT
ATTACTTGCAAAGATAAACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSFDADVIIVGGGLSGLSAGITAVKEGLNVILLERGEYSGAKNVSGGRMYIHALQKLIPDALERAPLERPITKETYEFYC
KNKKLIFSFEEKGKKNSYSVLRAKFDRWLASEAESLGLLISYSTLVTNAYRENGGITLETNRGTLRAPLVIDASGVTSVV
FRYLGLRNFTPDKWMLGVKEIVKANVSLSEDEGEARTIVGLINGVKGGGFVYTNKDTLSVGMAVTFDSLPKSEVPAKDLV
ENFREKLGIEGEILEYSAHAIPYYGFKNLQQLYADNLIAVGDSAGFLINDGFTIRGMDLAIASGMIAGLVAKKIVEMKDF
TKTNIYYDMLKESFVLKHLELAYSRFELINRGTTLNNYTEILCDLLSDMFTVTEDRKTLIEYALLKLKEKGISLTQAIRD
MVSAVK

Sequences:

>Translated_406_residues
MSFDADVIIVGGGLSGLSAGITAVKEGLNVILLERGEYSGAKNVSGGRMYIHALQKLIPDALERAPLERPITKETYEFYC
KNKKLIFSFEEKGKKNSYSVLRAKFDRWLASEAESLGLLISYSTLVTNAYRENGGITLETNRGTLRAPLVIDASGVTSVV
FRYLGLRNFTPDKWMLGVKEIVKANVSLSEDEGEARTIVGLINGVKGGGFVYTNKDTLSVGMAVTFDSLPKSEVPAKDLV
ENFREKLGIEGEILEYSAHAIPYYGFKNLQQLYADNLIAVGDSAGFLINDGFTIRGMDLAIASGMIAGLVAKKIVEMKDF
TKTNIYYDMLKESFVLKHLELAYSRFELINRGTTLNNYTEILCDLLSDMFTVTEDRKTLIEYALLKLKEKGISLTQAIRD
MVSAVK
>Mature_405_residues
SFDADVIIVGGGLSGLSAGITAVKEGLNVILLERGEYSGAKNVSGGRMYIHALQKLIPDALERAPLERPITKETYEFYCK
NKKLIFSFEEKGKKNSYSVLRAKFDRWLASEAESLGLLISYSTLVTNAYRENGGITLETNRGTLRAPLVIDASGVTSVVF
RYLGLRNFTPDKWMLGVKEIVKANVSLSEDEGEARTIVGLINGVKGGGFVYTNKDTLSVGMAVTFDSLPKSEVPAKDLVE
NFREKLGIEGEILEYSAHAIPYYGFKNLQQLYADNLIAVGDSAGFLINDGFTIRGMDLAIASGMIAGLVAKKIVEMKDFT
KTNIYYDMLKESFVLKHLELAYSRFELINRGTTLNNYTEILCDLLSDMFTVTEDRKTLIEYALLKLKEKGISLTQAIRDM
VSAVK

Specific function: Could be part of an electron transfer system required for anaerobic carnitine reduction [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF-QO/fixC family [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=385, Percent_Identity=24.4155844155844, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1786227, Length=420, Percent_Identity=32.8571428571429, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI1787991, Length=388, Percent_Identity=32.4742268041237, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI87082155, Length=387, Percent_Identity=33.0749354005168, Blast_Score=178, Evalue=5e-46,
Organism=Drosophila melanogaster, GI24652256, Length=384, Percent_Identity=27.0833333333333, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: 1.5.5.-

Molecular weight: Translated: 44872; Mature: 44741

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFDADVIIVGGGLSGLSAGITAVKEGLNVILLERGEYSGAKNVSGGRMYIHALQKLIPD
CCCCCCEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
ALERAPLERPITKETYEFYCKNKKLIFSFEEKGKKNSYSVLRAKFDRWLASEAESLGLLI
HHHHCCCCCCCCHHHHHHHCCCCEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHCEEEE
SYSTLVTNAYRENGGITLETNRGTLRAPLVIDASGVTSVVFRYLGLRNFTPDKWMLGVKE
EHHHHHHHHHHCCCCEEEEECCCEEEECEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHH
IVKANVSLSEDEGEARTIVGLINGVKGGGFVYTNKDTLSVGMAVTFDSLPKSEVPAKDLV
HHHCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCEEEEEEEEECCCCCCCCCHHHHH
ENFREKLGIEGEILEYSAHAIPYYGFKNLQQLYADNLIAVGDSAGFLINDGFTIRGMDLA
HHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCEEEECCCCCEEEECCEEEECHHHH
IASGMIAGLVAKKIVEMKDFTKTNIYYDMLKESFVLKHLELAYSRFELINRGTTLNNYTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ILCDLLSDMFTVTEDRKTLIEYALLKLKEKGISLTQAIRDMVSAVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SFDADVIIVGGGLSGLSAGITAVKEGLNVILLERGEYSGAKNVSGGRMYIHALQKLIPD
CCCCCEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
ALERAPLERPITKETYEFYCKNKKLIFSFEEKGKKNSYSVLRAKFDRWLASEAESLGLLI
HHHHCCCCCCCCHHHHHHHCCCCEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHCEEEE
SYSTLVTNAYRENGGITLETNRGTLRAPLVIDASGVTSVVFRYLGLRNFTPDKWMLGVKE
EHHHHHHHHHHCCCCEEEEECCCEEEECEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHH
IVKANVSLSEDEGEARTIVGLINGVKGGGFVYTNKDTLSVGMAVTFDSLPKSEVPAKDLV
HHHCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCEEEEEEEEECCCCCCCCCHHHHH
ENFREKLGIEGEILEYSAHAIPYYGFKNLQQLYADNLIAVGDSAGFLINDGFTIRGMDLA
HHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCEEEECCCCCEEEECCEEEECHHHH
IASGMIAGLVAKKIVEMKDFTKTNIYYDMLKESFVLKHLELAYSRFELINRGTTLNNYTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ILCDLLSDMFTVTEDRKTLIEYALLKLKEKGISLTQAIRDMVSAVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]