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The map label for this gene is dmsB [H]

Identifier: 15922102

GI number: 15922102

Start: 1807229

End: 1808404

Strand: Reverse

Name: dmsB [H]

Synonym: ST1789

Alternate gene names: 15922102

Gene position: 1808404-1807229 (Counterclockwise)

Preceding gene: 15922103

Following gene: 15922101

Centisome position: 67.11

GC content: 33.84

Gene sequence:

>1176_bases
ATGGAGAGAAGTCTAGGATTTATATTCGATCCTAACAAATGCATAGTCTGTAATGCTTGCGTTAATGCTTGTAATGAACA
TTATGGAAACCTGAACTGGAGATCCCTTTTAGTGTTTCAAAATGAGGTAAAAATTGGTATTTCTATTGCTTGTAATCATT
GTGAAAACCCCCTTTGTATGAAAGTTTGCCCAGCTAATGCTATACATAAAGATGATATGGGAATAGTTTACATAAATGGT
AATGAATGTATAGGTTGTGGTTATTGCCAATGGGCTTGTCCTTATGAAGAACCTAAGTTTAACCATGAAGGAATAATGAC
AAAGTGTGATTTATGTAGGCAAAGGATTTTGAAAAAAGAAGGATTGCCTTATTGTGTTGAATCATGTCCTACTGGTGCAC
TATCTTTCGGTTGGATAGATAAACCTAAATATGATGCACCTTACCTAGCACCTTATGATATTACAAAACCTAAGCTTGAA
ATAAAGAAGCCCAAAGAGGAAGAGATCAAGGCTTCACCGCTAAAGAGAAGAAGAGAGGAAAGATATATTGAACTTTTACT
CTTTACAATTCTTTCTGAACTCTCTCTAGGGATTCTTATAACTAGGATTCCGTTTTATTCCTTAATCTCTCTCATTCTTT
TAGCTATTGGTTTAGTTCCGTCGATTTTCCACGTTAATAGAAGAGAAAGGGCTTATAGGGTTATAATGAATTTAAAATCT
TCTTGGCTTAGTAGGGAAGTATTCTTTGGCGGTTTATCATTCCTTTCATTACTACTGGAACTCGTAACACCTAGTTTATA
CTACTTATCAGTTATACTAATTTCCTTATCTGTATTTTCGTCCATTATGATATATATGCTAAAGACCACACCCTCTTGGT
ATAATCCTAATACACCGTTATCCTTCATAGGTACTATATTTACCGTATTCCCATTAGGATTTTACTTCACTCACTCTCTG
CTATTCTTACTAATTCCTTTAGTTTTTGGAGTTATTGAAATAAGTCTTGCAAGGAAAGAGAAAATACTACATATACCGTA
TTTGATACTCTTGGTAATTTCTATCTTTATCCCGTTAATAAGTATTCTAGCCTCATTAGTTGGTATTTCATCAGAAATCA
TAGCAAGACGTAATTTCTTTGAAAAGATTACATACTACGGTCTACCAAGTCCATAA

Upstream 100 bases:

>100_bases
ACTATGAAGTTTATTCTAATCTATTCCTTTTTTAAAAATTTGGAGGACTTTTTAGAATTATAAATGGCAAGTTTATAAAG
TTACAATACAAAATTAAGTT

Downstream 100 bases:

>100_bases
ACTTTTTTAATACTCAACTTTTTAAAGTATGGAAAATAAATTACATTTTGAGAGTGGTTTTTATTGCTCGAAATAAGATT
TCACGGGAGAGGGGGACAAG

Product: anaerobic dimethyl sulfoxide reductase

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase iron-sulfur subunit [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MERSLGFIFDPNKCIVCNACVNACNEHYGNLNWRSLLVFQNEVKIGISIACNHCENPLCMKVCPANAIHKDDMGIVYING
NECIGCGYCQWACPYEEPKFNHEGIMTKCDLCRQRILKKEGLPYCVESCPTGALSFGWIDKPKYDAPYLAPYDITKPKLE
IKKPKEEEIKASPLKRRREERYIELLLFTILSELSLGILITRIPFYSLISLILLAIGLVPSIFHVNRRERAYRVIMNLKS
SWLSREVFFGGLSFLSLLLELVTPSLYYLSVILISLSVFSSIMIYMLKTTPSWYNPNTPLSFIGTIFTVFPLGFYFTHSL
LFLLIPLVFGVIEISLARKEKILHIPYLILLVISIFIPLISILASLVGISSEIIARRNFFEKITYYGLPSP

Sequences:

>Translated_391_residues
MERSLGFIFDPNKCIVCNACVNACNEHYGNLNWRSLLVFQNEVKIGISIACNHCENPLCMKVCPANAIHKDDMGIVYING
NECIGCGYCQWACPYEEPKFNHEGIMTKCDLCRQRILKKEGLPYCVESCPTGALSFGWIDKPKYDAPYLAPYDITKPKLE
IKKPKEEEIKASPLKRRREERYIELLLFTILSELSLGILITRIPFYSLISLILLAIGLVPSIFHVNRRERAYRVIMNLKS
SWLSREVFFGGLSFLSLLLELVTPSLYYLSVILISLSVFSSIMIYMLKTTPSWYNPNTPLSFIGTIFTVFPLGFYFTHSL
LFLLIPLVFGVIEISLARKEKILHIPYLILLVISIFIPLISILASLVGISSEIIARRNFFEKITYYGLPSP
>Mature_391_residues
MERSLGFIFDPNKCIVCNACVNACNEHYGNLNWRSLLVFQNEVKIGISIACNHCENPLCMKVCPANAIHKDDMGIVYING
NECIGCGYCQWACPYEEPKFNHEGIMTKCDLCRQRILKKEGLPYCVESCPTGALSFGWIDKPKYDAPYLAPYDITKPKLE
IKKPKEEEIKASPLKRRREERYIELLLFTILSELSLGILITRIPFYSLISLILLAIGLVPSIFHVNRRERAYRVIMNLKS
SWLSREVFFGGLSFLSLLLELVTPSLYYLSVILISLSVFSSIMIYMLKTTPSWYNPNTPLSFIGTIFTVFPLGFYFTHSL
LFLLIPLVFGVIEISLARKEKILHIPYLILLVISIFIPLISILASLVGISSEIIARRNFFEKITYYGLPSP

Specific function: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=185, Percent_Identity=39.4594594594595, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1787872, Length=185, Percent_Identity=37.8378378378378, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789370, Length=169, Percent_Identity=34.9112426035503, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI2367345, Length=149, Percent_Identity=38.9261744966443, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI226510944, Length=155, Percent_Identity=34.8387096774194, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1790326, Length=162, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787749, Length=156, Percent_Identity=35.2564102564103, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082180, Length=130, Percent_Identity=35.3846153846154, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI2367245, Length=147, Percent_Identity=34.0136054421769, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87082179, Length=142, Percent_Identity=36.6197183098592, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789067, Length=153, Percent_Identity=33.9869281045752, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788811, Length=146, Percent_Identity=29.4520547945205, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR014297 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 44586; Mature: 44586

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERSLGFIFDPNKCIVCNACVNACNEHYGNLNWRSLLVFQNEVKIGISIACNHCENPLCM
CCCCCCEEECCCCEEEEHHHHHHHHHHCCCCCCEEEEEEECCEEEEEEEEECCCCCCCEE
KVCPANAIHKDDMGIVYINGNECIGCGYCQWACPYEEPKFNHEGIMTKCDLCRQRILKKE
EECCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GLPYCVESCPTGALSFGWIDKPKYDAPYLAPYDITKPKLEIKKPKEEEIKASPLKRRREE
CCCHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHCCHHHHHHHH
RYIELLLFTILSELSLGILITRIPFYSLISLILLAIGLVPSIFHVNRRERAYRVIMNLKS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SWLSREVFFGGLSFLSLLLELVTPSLYYLSVILISLSVFSSIMIYMLKTTPSWYNPNTPL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
SFIGTIFTVFPLGFYFTHSLLFLLIPLVFGVIEISLARKEKILHIPYLILLVISIFIPLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILASLVGISSEIIARRNFFEKITYYGLPSP
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MERSLGFIFDPNKCIVCNACVNACNEHYGNLNWRSLLVFQNEVKIGISIACNHCENPLCM
CCCCCCEEECCCCEEEEHHHHHHHHHHCCCCCCEEEEEEECCEEEEEEEEECCCCCCCEE
KVCPANAIHKDDMGIVYINGNECIGCGYCQWACPYEEPKFNHEGIMTKCDLCRQRILKKE
EECCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GLPYCVESCPTGALSFGWIDKPKYDAPYLAPYDITKPKLEIKKPKEEEIKASPLKRRREE
CCCHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHCCHHHHHHHH
RYIELLLFTILSELSLGILITRIPFYSLISLILLAIGLVPSIFHVNRRERAYRVIMNLKS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SWLSREVFFGGLSFLSLLLELVTPSLYYLSVILISLSVFSSIMIYMLKTTPSWYNPNTPL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
SFIGTIFTVFPLGFYFTHSLLFLLIPLVFGVIEISLARKEKILHIPYLILLVISIFIPLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SILASLVGISSEIIARRNFFEKITYYGLPSP
HHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Iron-Sulfur Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 2174699; 1653010 [H]