Click here to switch to the map view.

The map label for this gene is dpo2 [H]

Identifier: 15921983

GI number: 15921983

Start: 1678455

End: 1680077

Strand: Reverse

Name: dpo2 [H]

Synonym: ST1680

Alternate gene names: 15921983

Gene position: 1680077-1678455 (Counterclockwise)

Preceding gene: 15921984

Following gene: 15921982

Centisome position: 62.35

GC content: 33.89

Gene sequence:

>1623_bases
ATGGAAGAAATTGTACTCGACGCTTATCCGACAAAAGGAGGAATAAAACTTCTGTTAAATGATTTTAGGACTGAATTCAT
AAAGACAACTTTCCCAGTTTACGTAATAACTGATAACCCAGACATTGTTCTTCAACATCCCGAAGTTAAATACTACGAAA
AAGAAAAATGGAGAAGCCTAGACGGTAAAGAAGTTGAACTTTACAGATTCGAGGTTGAAAGCTTTAACGCTTATTATTAC
ATAAGGAAAAGGTTAAAGGTAGTCAACGAAATACCAACAGTTCTGGCACAAACACTGTATAGGTTGAAAATTCCCTTAGT
AGATAAGATAGAGAAAGTTAATTATGCTACGGTAAAATTCCTTAGATGGTATGATGGTTGTTCAGACTGTTATGAAATAA
ATGGTGAAAGAGTTTATAATTTAGAGGACTTTGAGGCTGATGTTGTAGAATGTTACGGTTTTCCTTGCAAGAGAATTAGA
GCCCACGTTAAGATTCAAGGAGAGAAGAAAAGATCACCAGTATCTATAAAGGGACTTCTTGAGTGGTCTTATATATCCAA
AACGCCATTACATGAGATTGCTTACTCAACTATTGGAAAAGCGTTAACCACAAACGAAGCATGGGTTGCCTTAAAGAAAA
GGATCATAATACAAAATATTGTTACTAGATTAGAGAAATTAAGAAAATTAGAGGACATAATGAGAGCAGATAAGGGAGGT
TTATTTATATTCCCTAAACCTGGTTGTTATGAGGACGTTTATCAAATAGATTTTAAATCAATGTATCCTTCTCTTATTAT
AAAATATAATATATCCGCTGAAACTGTTGACGCTTGTGATGATATAAAGACTGAATTACATTCAATTTGTCTTAAAGAAA
AGGGTATTGTACCAGAAGCGTTAGAGTGGCTTGTAAAGAGAAAAGAAGAACTAAAGAAAATTGATGAAGAGAGAGCGGAA
GCAATAAAATGGATTTTAGTAGCATCTTTTGGTTATTTGGGGTATAGGAACTCTAGATTTGGAAAAATAGAAGCATATGA
GATGGTTACTTATTTTGCTAGAAAAACGCTGAGGAAAACGGTTGAAATAGCTGAAAGTTTAGGGATTAAAGTACTTCACG
GTATAATTGATTCTTTAATAGTAAAGGGGGACGTTTTAAAACTGATTGAAGCTGTAGAAAAAGAAACTGGCTTAAAGCTG
GATTACAAGAAGTTTAAGTGGGTCATTTTTACAGCTAGCAGAAACGATACGCCTTATCCAACAAGGTATATAGGAAATAA
AGATGATGGAGAAATTATAGCTAAAGGACTGGTAAGGAGCAATATGCCTAACATTGTGAAGTCCTACCTAAACGATTCTC
TCGAAATTCTTTCAAAGACTAAAGACTGTAATGAAGTCAAAGCAAGTGTAAAGAAAATTAAGGAACTTTTAGACTATTAT
AAAAGAAGAGTAATTAACGGTGAGCCAGACGATTATGTTATTTGGATCAAGGACGTTCCATATGTTAGGGGAATAAAAGG
TTTTTATGATGCTAGGGAAGGATTTAAGGGTAAAGATGTTGGCTACTATAAGGCATACCTAGAAAGGATATTTGAGGATT
TAACTAAGGTGATTAAATGCTGA

Upstream 100 bases:

>100_bases
AAGTTAGATACGTCCAAAGCGCTTCTTACGACGAATTTGTTGACCCCTATAATTTAGTGTATTTTACATTTATTTGGACT
TTAGCGGAGGAGTGTGAAAA

Downstream 100 bases:

>100_bases
GAACTGGTTTTGCATTTTTAGACGAAATAATAGAAAAGGATCAAATTGTAGAGTTCTTTTCTCCAGATGAAGAGTTACTG
AGGATATTTTATCATAGGGT

Product: DNA-directed DNA polymerase II

Products: NA

Alternate protein names: DNA polymerase B2; DNA polymerase II [H]

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MEEIVLDAYPTKGGIKLLLNDFRTEFIKTTFPVYVITDNPDIVLQHPEVKYYEKEKWRSLDGKEVELYRFEVESFNAYYY
IRKRLKVVNEIPTVLAQTLYRLKIPLVDKIEKVNYATVKFLRWYDGCSDCYEINGERVYNLEDFEADVVECYGFPCKRIR
AHVKIQGEKKRSPVSIKGLLEWSYISKTPLHEIAYSTIGKALTTNEAWVALKKRIIIQNIVTRLEKLRKLEDIMRADKGG
LFIFPKPGCYEDVYQIDFKSMYPSLIIKYNISAETVDACDDIKTELHSICLKEKGIVPEALEWLVKRKEELKKIDEERAE
AIKWILVASFGYLGYRNSRFGKIEAYEMVTYFARKTLRKTVEIAESLGIKVLHGIIDSLIVKGDVLKLIEAVEKETGLKL
DYKKFKWVIFTASRNDTPYPTRYIGNKDDGEIIAKGLVRSNMPNIVKSYLNDSLEILSKTKDCNEVKASVKKIKELLDYY
KRRVINGEPDDYVIWIKDVPYVRGIKGFYDAREGFKGKDVGYYKAYLERIFEDLTKVIKC

Sequences:

>Translated_540_residues
MEEIVLDAYPTKGGIKLLLNDFRTEFIKTTFPVYVITDNPDIVLQHPEVKYYEKEKWRSLDGKEVELYRFEVESFNAYYY
IRKRLKVVNEIPTVLAQTLYRLKIPLVDKIEKVNYATVKFLRWYDGCSDCYEINGERVYNLEDFEADVVECYGFPCKRIR
AHVKIQGEKKRSPVSIKGLLEWSYISKTPLHEIAYSTIGKALTTNEAWVALKKRIIIQNIVTRLEKLRKLEDIMRADKGG
LFIFPKPGCYEDVYQIDFKSMYPSLIIKYNISAETVDACDDIKTELHSICLKEKGIVPEALEWLVKRKEELKKIDEERAE
AIKWILVASFGYLGYRNSRFGKIEAYEMVTYFARKTLRKTVEIAESLGIKVLHGIIDSLIVKGDVLKLIEAVEKETGLKL
DYKKFKWVIFTASRNDTPYPTRYIGNKDDGEIIAKGLVRSNMPNIVKSYLNDSLEILSKTKDCNEVKASVKKIKELLDYY
KRRVINGEPDDYVIWIKDVPYVRGIKGFYDAREGFKGKDVGYYKAYLERIFEDLTKVIKC
>Mature_540_residues
MEEIVLDAYPTKGGIKLLLNDFRTEFIKTTFPVYVITDNPDIVLQHPEVKYYEKEKWRSLDGKEVELYRFEVESFNAYYY
IRKRLKVVNEIPTVLAQTLYRLKIPLVDKIEKVNYATVKFLRWYDGCSDCYEINGERVYNLEDFEADVVECYGFPCKRIR
AHVKIQGEKKRSPVSIKGLLEWSYISKTPLHEIAYSTIGKALTTNEAWVALKKRIIIQNIVTRLEKLRKLEDIMRADKGG
LFIFPKPGCYEDVYQIDFKSMYPSLIIKYNISAETVDACDDIKTELHSICLKEKGIVPEALEWLVKRKEELKKIDEERAE
AIKWILVASFGYLGYRNSRFGKIEAYEMVTYFARKTLRKTVEIAESLGIKVLHGIIDSLIVKGDVLKLIEAVEKETGLKL
DYKKFKWVIFTASRNDTPYPTRYIGNKDDGEIIAKGLVRSNMPNIVKSYLNDSLEILSKTKDCNEVKASVKKIKELLDYY
KRRVINGEPDDYVIWIKDVPYVRGIKGFYDAREGFKGKDVGYYKAYLERIFEDLTKVIKC

Specific function: This polymerase is devoid of exonuclease activity [H]

COG id: COG0417

COG function: function code L; DNA polymerase elongation subunit (family B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA polymerase type-B family [H]

Homologues:

Organism=Homo sapiens, GI106507301, Length=178, Percent_Identity=29.2134831460674, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32565317, Length=167, Percent_Identity=29.940119760479, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324227, Length=177, Percent_Identity=32.2033898305085, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24648780, Length=164, Percent_Identity=31.7073170731707, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006172
- InterPro:   IPR006134
- InterPro:   IPR023211 [H]

Pfam domain/function: PF00136 DNA_pol_B [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 62960; Mature: 62960

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEIVLDAYPTKGGIKLLLNDFRTEFIKTTFPVYVITDNPDIVLQHPEVKYYEKEKWRSL
CCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCHHHHHHHCCC
DGKEVELYRFEVESFNAYYYIRKRLKVVNEIPTVLAQTLYRLKIPLVDKIEKVNYATVKF
CCCEEEEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHH
LRWYDGCSDCYEINGERVYNLEDFEADVVECYGFPCKRIRAHVKIQGEKKRSPVSIKGLL
HHHHCCCCHHHHCCCCEEECCCHHHHHHHHHCCCCHHHCEEEEEEECCCCCCCEEEEEEE
EWSYISKTPLHEIAYSTIGKALTTNEAWVALKKRIIIQNIVTRLEKLRKLEDIMRADKGG
EEHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LFIFPKPGCYEDVYQIDFKSMYPSLIIKYNISAETVDACDDIKTELHSICLKEKGIVPEA
EEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
LEWLVKRKEELKKIDEERAEAIKWILVASFGYLGYRNSRFGKIEAYEMVTYFARKTLRKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VEIAESLGIKVLHGIIDSLIVKGDVLKLIEAVEKETGLKLDYKKFKWVIFTASRNDTPYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCCCCCC
TRYIGNKDDGEIIAKGLVRSNMPNIVKSYLNDSLEILSKTKDCNEVKASVKKIKELLDYY
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
KRRVINGEPDDYVIWIKDVPYVRGIKGFYDAREGFKGKDVGYYKAYLERIFEDLTKVIKC
HHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEEIVLDAYPTKGGIKLLLNDFRTEFIKTTFPVYVITDNPDIVLQHPEVKYYEKEKWRSL
CCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCHHHHHHHCCC
DGKEVELYRFEVESFNAYYYIRKRLKVVNEIPTVLAQTLYRLKIPLVDKIEKVNYATVKF
CCCEEEEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHH
LRWYDGCSDCYEINGERVYNLEDFEADVVECYGFPCKRIRAHVKIQGEKKRSPVSIKGLL
HHHHCCCCHHHHCCCCEEECCCHHHHHHHHHCCCCHHHCEEEEEEECCCCCCCEEEEEEE
EWSYISKTPLHEIAYSTIGKALTTNEAWVALKKRIIIQNIVTRLEKLRKLEDIMRADKGG
EEHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LFIFPKPGCYEDVYQIDFKSMYPSLIIKYNISAETVDACDDIKTELHSICLKEKGIVPEA
EEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
LEWLVKRKEELKKIDEERAEAIKWILVASFGYLGYRNSRFGKIEAYEMVTYFARKTLRKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VEIAESLGIKVLHGIIDSLIVKGDVLKLIEAVEKETGLKLDYKKFKWVIFTASRNDTPYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCCCCCC
TRYIGNKDDGEIIAKGLVRSNMPNIVKSYLNDSLEILSKTKDCNEVKASVKKIKELLDYY
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
KRRVINGEPDDYVIWIKDVPYVRGIKGFYDAREGFKGKDVGYYKAYLERIFEDLTKVIKC
HHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8332474; 11427726 [H]