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The map label for this gene is coxL [H]

Identifier: 15921868

GI number: 15921868

Start: 1567612

End: 1569693

Strand: Direct

Name: coxL [H]

Synonym: ST1571

Alternate gene names: 15921868

Gene position: 1567612-1569693 (Clockwise)

Preceding gene: 15921867

Following gene: 15921869

Centisome position: 58.17

GC content: 37.13

Gene sequence:

>2082_bases
ATGAAAAGGTTAGATGTAATAGATTTAATTAAAGGAAAGGGAAATTACATAGATGACTATCCTTTTAAGGGTAAATATGC
TGTATTTGTGAGAAGTCCTTATCCTCATGCAAGAATAAAGAAGATAGATACGAGTGAAGCCGAGAAAAAGGGGGCTTTGG
TTTTAACTGGTAAAGATATTATTGCAAGAAGAGTAGAGGCAGGCGAAAGAGAAGGTGCAGGATTATCAACAATGTTAATG
GCTACAAATAAGGCTTTATATGTTGGTCAGCCAGTAGCTTTGGTAATTGCTAATGATCCATATGAAGCCACAGATTTAGC
AGAGTTAATACAGGTGGATTACGAGCCTCTAGAACCAATACCTAATATAGAGAAAGCGTTGAAGGGCGAAGTTTACGTAT
TTGATGAGTTAAGGAGTAACGTTGTAAGAGAGCAAAGTTTTGAGTTTGGTAAAATATCTAATCAAGGGAAAGAATTAGAG
CTAGATTTGTATTGGTCTAGGAGTAGTGGAAATCCAATTGAAACTTTTGGAGCAATAGTTATTCCTACTACTCAAGGTTT
AGAAATAATTTCAAATCAACAAGCTGGAAATTTTGTTATTTCCGAGTTAGAAAAAGCCTTAGGAGTTAAGGTGATACATA
AAAATGCTAGACAAGGTGGTAGTTTCGGTTCTAAATTTTCTTTAGTTAGATACTTATCAGTATTAGCTTTCGCGTCGTTG
AAATTTAAAGTACCAATAAAGTGGATAGAAACTAGAACTGAACATTTGTTAGCTTCAAATAGTAGTGGGCCAGAAAGAAA
ATTCAAAATTAAAGCCTATTATGATTCGCGCGGTAAAGTGAATTTCTTAGATATTCATATTTGGGAAGATGTAGGGGCAT
CATTAGAGGCTGGGCAACCATTTAAACCGTTAGGACATTTAACTGGCCCATATAAGATACCCGGGATTAGATACACTGCA
ACTTTAGTAGCCACGAATAAGAACCCACCTGGTGCATTTAGGGGTGCTGGTACACCTCCACATACATGGGCATTAGAAAG
AGTTATGGATGCAATAGCTGATGAATTAGGTTTAGATAGGGCTGAGGTTAGAAAAACTAACGTGATCGACTCTTTCCCAT
ATGATAGTGGATTTGCCTATTATGATTCTGGTAATCCTAGTGGGTTGCTTGAAATGGCATTATCAAGGAAGGATATATTC
TCGATGAGGGATGAAAAAACTGGTGTTGGTTTAGCATTATCTACTGATCCTAGTACACCTTCTGGGAGCGAGAGAGTTAA
GTTAAAAATAAAGAATGGTAAAGTCGTGGTAGGGTTAGGCTTTGGACCGGAAGGACAGGGAAATGAACATACAGCTGTTT
TGTTAGTCTCGAAACTTCTTGGAATCCCAACAGATCTAGTGACTTATGAAATTTTAGATAATAATGAACTGACTTCATCC
TTTGGTCCCGGTGGAAGTAGAATGGCTGCTTTCACTTATGGGGCTATAAGTGGTGCTGTAGAAGAGTTGAAGGCTAAGCT
AAAAAGAGAAGCTGAGAGTCTTATAGGAAATGCTGAGTATAAAGATGGATACTTCCTTGGTGAACATGGTAAAATAGGAA
TTACGCAATTTGAGGGAGAAGAAGTAACTTTTACTTTCTCCCTTCAAGGGAAATATAGATTTAATGCATACCCATTTGCT
TGTGATTTAGCTGTAGTTAGAATTGAAGATGGCAAAATTAAACCGATAAAGCATGTTGTTTATATAGATCCAGGTAATCC
AATAGACGAAGATCTTGTAAAAGAACAAGTTATTGGCGGTACAGCAATAGGAATTTCTATCGCACTTTATGAATCTTACG
TTTATGATGATCAGGGTAATTTATTAACTACCAGTTTAGCAGACTACGGTTTACCAACAGCATTAGATTTACCAGAAATC
GAGATTAATATTGTACCAACACCTTCTCCAGTTACGCCAGGAGGCGTAAAAGGAATTGGTGAGATACCAGTTGGTGTTGC
TGCTGCAGCTGTAACTAGTGCTGTAGAAGATGTTCTAAAGAGAAGGGTTAAAAAAGTGCCCATAAGGTTAGATGATTTTT
AA

Upstream 100 bases:

>100_bases
GTTAAATCGAAGGAGGAATTAAGGATAAGAGCTCAAGAGGAGAATGAACCCGAACTATTCGGAAATAAACTTTAATAATT
TTTAACGTTATCAACTTCTA

Downstream 100 bases:

>100_bases
ATTTGTTTAATTATTATTCAATATACTCCTCTATTTTAATAAGCCTTAATCTTCTGTTTATTAGGAATAATATTTATAAT
GATACATTTTGTTTATTTCT

Product: quinoline 2-oxidoreductase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 693; Mature: 693

Protein sequence:

>693_residues
MKRLDVIDLIKGKGNYIDDYPFKGKYAVFVRSPYPHARIKKIDTSEAEKKGALVLTGKDIIARRVEAGEREGAGLSTMLM
ATNKALYVGQPVALVIANDPYEATDLAELIQVDYEPLEPIPNIEKALKGEVYVFDELRSNVVREQSFEFGKISNQGKELE
LDLYWSRSSGNPIETFGAIVIPTTQGLEIISNQQAGNFVISELEKALGVKVIHKNARQGGSFGSKFSLVRYLSVLAFASL
KFKVPIKWIETRTEHLLASNSSGPERKFKIKAYYDSRGKVNFLDIHIWEDVGASLEAGQPFKPLGHLTGPYKIPGIRYTA
TLVATNKNPPGAFRGAGTPPHTWALERVMDAIADELGLDRAEVRKTNVIDSFPYDSGFAYYDSGNPSGLLEMALSRKDIF
SMRDEKTGVGLALSTDPSTPSGSERVKLKIKNGKVVVGLGFGPEGQGNEHTAVLLVSKLLGIPTDLVTYEILDNNELTSS
FGPGGSRMAAFTYGAISGAVEELKAKLKREAESLIGNAEYKDGYFLGEHGKIGITQFEGEEVTFTFSLQGKYRFNAYPFA
CDLAVVRIEDGKIKPIKHVVYIDPGNPIDEDLVKEQVIGGTAIGISIALYESYVYDDQGNLLTTSLADYGLPTALDLPEI
EINIVPTPSPVTPGGVKGIGEIPVGVAAAAVTSAVEDVLKRRVKKVPIRLDDF

Sequences:

>Translated_693_residues
MKRLDVIDLIKGKGNYIDDYPFKGKYAVFVRSPYPHARIKKIDTSEAEKKGALVLTGKDIIARRVEAGEREGAGLSTMLM
ATNKALYVGQPVALVIANDPYEATDLAELIQVDYEPLEPIPNIEKALKGEVYVFDELRSNVVREQSFEFGKISNQGKELE
LDLYWSRSSGNPIETFGAIVIPTTQGLEIISNQQAGNFVISELEKALGVKVIHKNARQGGSFGSKFSLVRYLSVLAFASL
KFKVPIKWIETRTEHLLASNSSGPERKFKIKAYYDSRGKVNFLDIHIWEDVGASLEAGQPFKPLGHLTGPYKIPGIRYTA
TLVATNKNPPGAFRGAGTPPHTWALERVMDAIADELGLDRAEVRKTNVIDSFPYDSGFAYYDSGNPSGLLEMALSRKDIF
SMRDEKTGVGLALSTDPSTPSGSERVKLKIKNGKVVVGLGFGPEGQGNEHTAVLLVSKLLGIPTDLVTYEILDNNELTSS
FGPGGSRMAAFTYGAISGAVEELKAKLKREAESLIGNAEYKDGYFLGEHGKIGITQFEGEEVTFTFSLQGKYRFNAYPFA
CDLAVVRIEDGKIKPIKHVVYIDPGNPIDEDLVKEQVIGGTAIGISIALYESYVYDDQGNLLTTSLADYGLPTALDLPEI
EINIVPTPSPVTPGGVKGIGEIPVGVAAAAVTSAVEDVLKRRVKKVPIRLDDF
>Mature_693_residues
MKRLDVIDLIKGKGNYIDDYPFKGKYAVFVRSPYPHARIKKIDTSEAEKKGALVLTGKDIIARRVEAGEREGAGLSTMLM
ATNKALYVGQPVALVIANDPYEATDLAELIQVDYEPLEPIPNIEKALKGEVYVFDELRSNVVREQSFEFGKISNQGKELE
LDLYWSRSSGNPIETFGAIVIPTTQGLEIISNQQAGNFVISELEKALGVKVIHKNARQGGSFGSKFSLVRYLSVLAFASL
KFKVPIKWIETRTEHLLASNSSGPERKFKIKAYYDSRGKVNFLDIHIWEDVGASLEAGQPFKPLGHLTGPYKIPGIRYTA
TLVATNKNPPGAFRGAGTPPHTWALERVMDAIADELGLDRAEVRKTNVIDSFPYDSGFAYYDSGNPSGLLEMALSRKDIF
SMRDEKTGVGLALSTDPSTPSGSERVKLKIKNGKVVVGLGFGPEGQGNEHTAVLLVSKLLGIPTDLVTYEILDNNELTSS
FGPGGSRMAAFTYGAISGAVEELKAKLKREAESLIGNAEYKDGYFLGEHGKIGITQFEGEEVTFTFSLQGKYRFNAYPFA
CDLAVVRIEDGKIKPIKHVVYIDPGNPIDEDLVKEQVIGGTAIGISIALYESYVYDDQGNLLTTSLADYGLPTALDLPEI
EINIVPTPSPVTPGGVKGIGEIPVGVAAAAVTSAVEDVLKRRVKKVPIRLDDF

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=744, Percent_Identity=24.7311827956989, Blast_Score=121, Evalue=3e-27,
Organism=Homo sapiens, GI91823271, Length=708, Percent_Identity=23.728813559322, Blast_Score=120, Evalue=3e-27,
Organism=Escherichia coli, GI1789230, Length=753, Percent_Identity=24.0371845949535, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789246, Length=772, Percent_Identity=22.6683937823834, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786478, Length=707, Percent_Identity=21.7821782178218, Blast_Score=83, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17540638, Length=712, Percent_Identity=24.1573033707865, Blast_Score=118, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32566215, Length=714, Percent_Identity=23.109243697479, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17737937, Length=729, Percent_Identity=24.2798353909465, Blast_Score=112, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 75523; Mature: 75523

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLDVIDLIKGKGNYIDDYPFKGKYAVFVRSPYPHARIKKIDTSEAEKKGALVLTGKDI
CCCCCEEHEECCCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCCHHHCCCEEEECHHH
IARRVEAGEREGAGLSTMLMATNKALYVGQPVALVIANDPYEATDLAELIQVDYEPLEPI
HHHHHHCCCCCCCCEEEEEEECCCEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCC
PNIEKALKGEVYVFDELRSNVVREQSFEFGKISNQGKELELDLYWSRSSGNPIETFGAIV
CCHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHCCEEE
IPTTQGLEIISNQQAGNFVISELEKALGVKVIHKNARQGGSFGSKFSLVRYLSVLAFASL
EECCCCCCEECCCCCCCHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHE
KFKVPIKWIETRTEHLLASNSSGPERKFKIKAYYDSRGKVNFLDIHIWEDVGASLEAGQP
EEEECHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCC
FKPLGHLTGPYKIPGIRYTATLVATNKNPPGAFRGAGTPPHTWALERVMDAIADELGLDR
CCCHHCCCCCEECCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCH
AEVRKTNVIDSFPYDSGFAYYDSGNPSGLLEMALSRKDIFSMRDEKTGVGLALSTDPSTP
HHHHHCCCEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
SGSERVKLKIKNGKVVVGLGFGPEGQGNEHTAVLLVSKLLGIPTDLVTYEILDNNELTSS
CCCCEEEEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHEEEEEECCCCCCCC
FGPGGSRMAAFTYGAISGAVEELKAKLKREAESLIGNAEYKDGYFLGEHGKIGITQFEGE
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEEEECCC
EVTFTFSLQGKYRFNAYPFACDLAVVRIEDGKIKPIKHVVYIDPGNPIDEDLVKEQVIGG
EEEEEEEECCEEEECCCCEEEEEEEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHCCC
TAIGISIALYESYVYDDQGNLLTTSLADYGLPTALDLPEIEINIVPTPSPVTPGGVKGIG
EEHEEEEEEEEEEEECCCCCEEEEEHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCC
EIPVGVAAAAVTSAVEDVLKRRVKKVPIRLDDF
CCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCC
>Mature Secondary Structure
MKRLDVIDLIKGKGNYIDDYPFKGKYAVFVRSPYPHARIKKIDTSEAEKKGALVLTGKDI
CCCCCEEHEECCCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCCHHHCCCEEEECHHH
IARRVEAGEREGAGLSTMLMATNKALYVGQPVALVIANDPYEATDLAELIQVDYEPLEPI
HHHHHHCCCCCCCCEEEEEEECCCEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCC
PNIEKALKGEVYVFDELRSNVVREQSFEFGKISNQGKELELDLYWSRSSGNPIETFGAIV
CCHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHCCEEE
IPTTQGLEIISNQQAGNFVISELEKALGVKVIHKNARQGGSFGSKFSLVRYLSVLAFASL
EECCCCCCEECCCCCCCHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHE
KFKVPIKWIETRTEHLLASNSSGPERKFKIKAYYDSRGKVNFLDIHIWEDVGASLEAGQP
EEEECHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCEEEEEEEEECCCCCCCCCCCC
FKPLGHLTGPYKIPGIRYTATLVATNKNPPGAFRGAGTPPHTWALERVMDAIADELGLDR
CCCHHCCCCCEECCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCH
AEVRKTNVIDSFPYDSGFAYYDSGNPSGLLEMALSRKDIFSMRDEKTGVGLALSTDPSTP
HHHHHCCCEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
SGSERVKLKIKNGKVVVGLGFGPEGQGNEHTAVLLVSKLLGIPTDLVTYEILDNNELTSS
CCCCEEEEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHEEEEEECCCCCCCC
FGPGGSRMAAFTYGAISGAVEELKAKLKREAESLIGNAEYKDGYFLGEHGKIGITQFEGE
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEEEECCC
EVTFTFSLQGKYRFNAYPFACDLAVVRIEDGKIKPIKHVVYIDPGNPIDEDLVKEQVIGG
EEEEEEEECCEEEECCCCEEEEEEEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHCCC
TAIGISIALYESYVYDDQGNLLTTSLADYGLPTALDLPEIEINIVPTPSPVTPGGVKGIG
EEHEEEEEEEEEEEECCCCCEEEEEHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCC
EIPVGVAAAAVTSAVEDVLKRRVKKVPIRLDDF
CCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 12515558; 10430865; 12475995 [H]