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The map label for this gene is lhr [C]

Identifier: 15921693

GI number: 15921693

Start: 1409061

End: 1411682

Strand: Direct

Name: lhr [C]

Synonym: ST1404

Alternate gene names: 15921693

Gene position: 1409061-1411682 (Clockwise)

Preceding gene: 15921692

Following gene: 15921697

Centisome position: 52.29

GC content: 31.54

Gene sequence:

>2622_bases
ATGGAAATTAATTATACAAATTACTTAACCGATGATGAAATACTAAGTATGTTAACGTTTCAAGTAGCACGTTGGTTTAA
AGAGAAATATAAGACCTTTACTCCTCCTCAGCGTGGTGCTATACCCTTAATAAAGATGAATAAAAATGTCTTGGTATCTA
GCCCTACTGGTAGTGGTAAGACGCTTGCAGCATTTCTTGGGATACTAGATACATTAATAGATTTGGGATATAAGAATCAA
TTAGAAGACAAAATTTATGCTATTTACATATCCCCTTTAAGGGCTCTTAATAATGATATGAAAAGAAATCTATTTGAACC
TTTACAAGAACTAAAAGAGAAAAACCCAGATTTACCCGAAATAAGAATTGCTGTAAGGACTAGTGATACTTCTTCCTATG
AAAAGCAAAAAATGTTACGAAATCCTCCTCACATTCTGATTACAACTCCAGAATCGTTTGGGATTTCCCTTGTTTCCCCA
AAATTTAGAGAGAAACTTAGTGATGCAAAATGGATTATAGTTGATGAGATTCATGAATTGGCTAATAGTAAACGAGGAGC
TTATTTGATGGGTATGTTAGAATTATATCAAGCCCTAGTTGCAAAAAATGAGTTAGTAAGAATAGGCTTAAGTGCTACAG
TATCTCCTTTAGATGAGGTAGCAAAATTCTTAGTTGGTAAAGACAGAGAATATAATATAGTAGACGCACGATTTGTAAAA
CCTATAGATATTAGAGTAATTTCGCCAGTGAAAGATTTAGTTCATGCAACAGAAGAAGAAGTAAGTCAAGGAATATATTC
ATACTTAGTAGAAGAAATAAAAAAACATAAAACAACTTTGATTTTCACTAATACAAGAAGTGCGGCTGAAAGAGTATCGT
ATAAATTAAGGAAAATTTTTGAGACACAGAAGATTTTCGACAGTGATTTAGTAGCAGCTCATCACAGTAGTCTTAGTAGG
GATGTAAGATTAGAAGTAGAGGAAAAGTTAAAAAGGGGAGAATTAAAGGTAGTCGTATCATCTACTAGCCTAGAGTTAGG
AATCGATATAGGATATATTGATCTAGTCATTCTTCTTAGTAGCCCAAAAAGTGTAAGTAGATTGTTACAAAGAATTGGAA
GAGCTGGACATAATATAAGGAATATAAGTAAAGGTAGAATTGTCGTTGTAGATAGAGATGATTTAGTAGAATGTACTGTT
TTAGCTAAGTTAGCTAGGGACAGAAAGATAGATAACATTCACATCCCAATGAAGCCTTTAGATGTTTTGTCTCAACTTAT
AGTAGCTGCTTCTTTAATTACTCCAGTTAATAAAGAAGAATTATTTAAAATTATAACTAGAGCTTATAATTATCATAACT
TAGATTATAAAGAATTTGATTCTGTTTTGTCATATTTACAAGGTAGTTATGAGCTAGAAGCTAAAAATGTGTACTCTAAG
ATTAGAGTTGAAAATAGCATAATTAAGCCTAAAAGAGGATCTAGAATGATATTCTTTTTAAATAGTGGTACTATTCCTGA
CGAAGCTAATATAGCAGTAAAGACAGAAGATGGAAAATATGTAGGCAATTTGGAAGAGGACTTTGCTGAAATTCTAATTC
CAGGTGACATATTTGTATTATCGGGGAAAACTTATGAGTTTATTAGAAGTGAAGGTAATCTAGCAATTGTTAGAAGTGCT
GAAGGTCAAAGGCCAACAGTTCCAAGTTGGTTTTCAGAAATGCTTCCTTTAGCTTACGATTCTGCATTAGAGGTTGGAAA
GTTTAGGGGCTTTGTGGCTAATTTAATTGAAAAAGGTATTGATGAGAAAAAAGCTATTGAGATTATATCAAAGGAATACG
AAATTAGCAAACATGCAGCTTGGTCTATATATGAATATGTATTAGAAGAGTACTTATTTACAAATGGTATTGTTCCTACT
GATAAATTAATTTTAATAGAAATTTATGATGATGAAGAGAATAGGAGAAATTTTATATTTCATGCTCTGTATGGTAGAAG
AGCTCTTGATGCATTATCTAGGGCAGTAGCTTTCGTAGTTAGTGAAGAATTAAATTTGGATGTGAGAGTATCTATTACTG
ATAATGGTTTTATTATAACTATACCTAAAATTATAGATTATGATATTAAGGATGTATTATATAAGTTAGACCCTAATGAA
CTGTATGAGATACTATCTAAGGTTATATTAAGAACAGAAATGATAAAGAAAAGATTCAGGCATTGTGCCGAAAGATCCTT
TATGCTCCTAAGACGTTATAAGGGAAAGGAAACTAGTATTGATAGAAGACAACTTAATTCAGAGATTCTATTAAATGTAG
TCAAAGAATATGAAGGATTTCCAGTATTGAAAGAAACAATAAGAGAAATATTGGAAGACTATATGGATATAGAAAAAGCC
ATAGAGATAGTTAAAAAAGTGAGAGAAAGAGAGATAGATGTAAAGGTCATAGGTCCTAACAGAATTCCTAGTCCATTTGC
TCATAATATTATCTTGAAAGAGCACTCTGATGTTGTGTTAGCTGAAGAAAAGAGAGATTTACTGAGAAAGTTGCATGATA
AGGTTATTGAATTCTTGAGGAATAAGGGAATTAATATCGATCTCAAATATACTGAAATCTAA

Upstream 100 bases:

>100_bases
TTAGCCTACTATTCTTCCGGTTTCTTGTATACTTTATTAACTTTTAACAAGGAATTATGAACAAATCTTTTTAATAGCCT
AACTAGTTATCTACATCTGG

Downstream 100 bases:

>100_bases
AATTCTATAGGATTTTACACAATTGTTACTAGCTATAATCCATGGAAAATTCCAGTAAATCATGCCTATTATATCAATGA
TGCTAGGCTCGCAAGACTCT

Product: ATP-dependent helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 873; Mature: 873

Protein sequence:

>873_residues
MEINYTNYLTDDEILSMLTFQVARWFKEKYKTFTPPQRGAIPLIKMNKNVLVSSPTGSGKTLAAFLGILDTLIDLGYKNQ
LEDKIYAIYISPLRALNNDMKRNLFEPLQELKEKNPDLPEIRIAVRTSDTSSYEKQKMLRNPPHILITTPESFGISLVSP
KFREKLSDAKWIIVDEIHELANSKRGAYLMGMLELYQALVAKNELVRIGLSATVSPLDEVAKFLVGKDREYNIVDARFVK
PIDIRVISPVKDLVHATEEEVSQGIYSYLVEEIKKHKTTLIFTNTRSAAERVSYKLRKIFETQKIFDSDLVAAHHSSLSR
DVRLEVEEKLKRGELKVVVSSTSLELGIDIGYIDLVILLSSPKSVSRLLQRIGRAGHNIRNISKGRIVVVDRDDLVECTV
LAKLARDRKIDNIHIPMKPLDVLSQLIVAASLITPVNKEELFKIITRAYNYHNLDYKEFDSVLSYLQGSYELEAKNVYSK
IRVENSIIKPKRGSRMIFFLNSGTIPDEANIAVKTEDGKYVGNLEEDFAEILIPGDIFVLSGKTYEFIRSEGNLAIVRSA
EGQRPTVPSWFSEMLPLAYDSALEVGKFRGFVANLIEKGIDEKKAIEIISKEYEISKHAAWSIYEYVLEEYLFTNGIVPT
DKLILIEIYDDEENRRNFIFHALYGRRALDALSRAVAFVVSEELNLDVRVSITDNGFIITIPKIIDYDIKDVLYKLDPNE
LYEILSKVILRTEMIKKRFRHCAERSFMLLRRYKGKETSIDRRQLNSEILLNVVKEYEGFPVLKETIREILEDYMDIEKA
IEIVKKVREREIDVKVIGPNRIPSPFAHNIILKEHSDVVLAEEKRDLLRKLHDKVIEFLRNKGINIDLKYTEI

Sequences:

>Translated_873_residues
MEINYTNYLTDDEILSMLTFQVARWFKEKYKTFTPPQRGAIPLIKMNKNVLVSSPTGSGKTLAAFLGILDTLIDLGYKNQ
LEDKIYAIYISPLRALNNDMKRNLFEPLQELKEKNPDLPEIRIAVRTSDTSSYEKQKMLRNPPHILITTPESFGISLVSP
KFREKLSDAKWIIVDEIHELANSKRGAYLMGMLELYQALVAKNELVRIGLSATVSPLDEVAKFLVGKDREYNIVDARFVK
PIDIRVISPVKDLVHATEEEVSQGIYSYLVEEIKKHKTTLIFTNTRSAAERVSYKLRKIFETQKIFDSDLVAAHHSSLSR
DVRLEVEEKLKRGELKVVVSSTSLELGIDIGYIDLVILLSSPKSVSRLLQRIGRAGHNIRNISKGRIVVVDRDDLVECTV
LAKLARDRKIDNIHIPMKPLDVLSQLIVAASLITPVNKEELFKIITRAYNYHNLDYKEFDSVLSYLQGSYELEAKNVYSK
IRVENSIIKPKRGSRMIFFLNSGTIPDEANIAVKTEDGKYVGNLEEDFAEILIPGDIFVLSGKTYEFIRSEGNLAIVRSA
EGQRPTVPSWFSEMLPLAYDSALEVGKFRGFVANLIEKGIDEKKAIEIISKEYEISKHAAWSIYEYVLEEYLFTNGIVPT
DKLILIEIYDDEENRRNFIFHALYGRRALDALSRAVAFVVSEELNLDVRVSITDNGFIITIPKIIDYDIKDVLYKLDPNE
LYEILSKVILRTEMIKKRFRHCAERSFMLLRRYKGKETSIDRRQLNSEILLNVVKEYEGFPVLKETIREILEDYMDIEKA
IEIVKKVREREIDVKVIGPNRIPSPFAHNIILKEHSDVVLAEEKRDLLRKLHDKVIEFLRNKGINIDLKYTEI
>Mature_873_residues
MEINYTNYLTDDEILSMLTFQVARWFKEKYKTFTPPQRGAIPLIKMNKNVLVSSPTGSGKTLAAFLGILDTLIDLGYKNQ
LEDKIYAIYISPLRALNNDMKRNLFEPLQELKEKNPDLPEIRIAVRTSDTSSYEKQKMLRNPPHILITTPESFGISLVSP
KFREKLSDAKWIIVDEIHELANSKRGAYLMGMLELYQALVAKNELVRIGLSATVSPLDEVAKFLVGKDREYNIVDARFVK
PIDIRVISPVKDLVHATEEEVSQGIYSYLVEEIKKHKTTLIFTNTRSAAERVSYKLRKIFETQKIFDSDLVAAHHSSLSR
DVRLEVEEKLKRGELKVVVSSTSLELGIDIGYIDLVILLSSPKSVSRLLQRIGRAGHNIRNISKGRIVVVDRDDLVECTV
LAKLARDRKIDNIHIPMKPLDVLSQLIVAASLITPVNKEELFKIITRAYNYHNLDYKEFDSVLSYLQGSYELEAKNVYSK
IRVENSIIKPKRGSRMIFFLNSGTIPDEANIAVKTEDGKYVGNLEEDFAEILIPGDIFVLSGKTYEFIRSEGNLAIVRSA
EGQRPTVPSWFSEMLPLAYDSALEVGKFRGFVANLIEKGIDEKKAIEIISKEYEISKHAAWSIYEYVLEEYLFTNGIVPT
DKLILIEIYDDEENRRNFIFHALYGRRALDALSRAVAFVVSEELNLDVRVSITDNGFIITIPKIIDYDIKDVLYKLDPNE
LYEILSKVILRTEMIKKRFRHCAERSFMLLRRYKGKETSIDRRQLNSEILLNVVKEYEGFPVLKETIREILEDYMDIEKA
IEIVKKVREREIDVKVIGPNRIPSPFAHNIILKEHSDVVLAEEKRDLLRKLHDKVIEFLRNKGINIDLKYTEI

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI40217847, Length=405, Percent_Identity=24.1975308641975, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI169218225, Length=407, Percent_Identity=24.3243243243243, Blast_Score=74, Evalue=5e-13,
Organism=Escherichia coli, GI1787942, Length=891, Percent_Identity=31.2008978675645, Blast_Score=409, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17508543, Length=363, Percent_Identity=24.7933884297521, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537519, Length=412, Percent_Identity=24.5145631067961, Blast_Score=73, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320497, Length=549, Percent_Identity=24.408014571949, Blast_Score=95, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI9755332, Length=394, Percent_Identity=27.4111675126904, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6321020, Length=395, Percent_Identity=23.7974683544304, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321710, Length=376, Percent_Identity=24.7340425531915, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647182, Length=389, Percent_Identity=27.5064267352185, Blast_Score=90, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24584399, Length=364, Percent_Identity=24.4505494505494, Blast_Score=76, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR017170 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 100292; Mature: 100292

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEINYTNYLTDDEILSMLTFQVARWFKEKYKTFTPPQRGAIPLIKMNKNVLVSSPTGSGK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEECCCCCCH
TLAAFLGILDTLIDLGYKNQLEDKIYAIYISPLRALNNDMKRNLFEPLQELKEKNPDLPE
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IRIAVRTSDTSSYEKQKMLRNPPHILITTPESFGISLVSPKFREKLSDAKWIIVDEIHEL
EEEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCEEECCHHHHHHCCCCCEEEHHHHHHH
ANSKRGAYLMGMLELYQALVAKNELVRIGLSATVSPLDEVAKFLVGKDREYNIVDARFVK
HCCCCCHHHHHHHHHHHHHHCCCHHEEEECCCCCCCHHHHHHHHHCCCCCCEEEHHEEEC
PIDIRVISPVKDLVHATEEEVSQGIYSYLVEEIKKHKTTLIFTNTRSAAERVSYKLRKIF
CEEEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHH
ETQKIFDSDLVAAHHSSLSRDVRLEVEEKLKRGELKVVVSSTSLELGIDIGYIDLVILLS
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCEEEEEEECCEEEEEEEHHHHEEEEEC
SPKSVSRLLQRIGRAGHNIRNISKGRIVVVDRDDLVECTVLAKLARDRKIDNIHIPMKPL
CCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEECCCCHH
DVLSQLIVAASLITPVNKEELFKIITRAYNYHNLDYKEFDSVLSYLQGSYELEAKNVYSK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHH
IRVENSIIKPKRGSRMIFFLNSGTIPDEANIAVKTEDGKYVGNLEEDFAEILIPGDIFVL
HHHHCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCCEECCHHHHHHHEEECCCEEEE
SGKTYEFIRSEGNLAIVRSAEGQRPTVPSWFSEMLPLAYDSALEVGKFRGFVANLIEKGI
CCCCEEHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DEKKAIEIISKEYEISKHAAWSIYEYVLEEYLFTNGIVPTDKLILIEIYDDEENRRNFIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCEEE
HALYGRRALDALSRAVAFVVSEELNLDVRVSITDNGFIITIPKIIDYDIKDVLYKLDPNE
EHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEHHHHCCCHHHHHHHCCHHH
LYEILSKVILRTEMIKKRFRHCAERSFMLLRRYKGKETSIDRRQLNSEILLNVVKEYEGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCC
PVLKETIREILEDYMDIEKAIEIVKKVREREIDVKVIGPNRIPSPFAHNIILKEHSDVVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHCCEEEECCCCEEE
AEEKRDLLRKLHDKVIEFLRNKGINIDLKYTEI
EHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
>Mature Secondary Structure
MEINYTNYLTDDEILSMLTFQVARWFKEKYKTFTPPQRGAIPLIKMNKNVLVSSPTGSGK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEECCCCCCH
TLAAFLGILDTLIDLGYKNQLEDKIYAIYISPLRALNNDMKRNLFEPLQELKEKNPDLPE
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IRIAVRTSDTSSYEKQKMLRNPPHILITTPESFGISLVSPKFREKLSDAKWIIVDEIHEL
EEEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCEEECCHHHHHHCCCCCEEEHHHHHHH
ANSKRGAYLMGMLELYQALVAKNELVRIGLSATVSPLDEVAKFLVGKDREYNIVDARFVK
HCCCCCHHHHHHHHHHHHHHCCCHHEEEECCCCCCCHHHHHHHHHCCCCCCEEEHHEEEC
PIDIRVISPVKDLVHATEEEVSQGIYSYLVEEIKKHKTTLIFTNTRSAAERVSYKLRKIF
CEEEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHH
ETQKIFDSDLVAAHHSSLSRDVRLEVEEKLKRGELKVVVSSTSLELGIDIGYIDLVILLS
HHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCEEEEEEECCEEEEEEEHHHHEEEEEC
SPKSVSRLLQRIGRAGHNIRNISKGRIVVVDRDDLVECTVLAKLARDRKIDNIHIPMKPL
CCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEECCCCHH
DVLSQLIVAASLITPVNKEELFKIITRAYNYHNLDYKEFDSVLSYLQGSYELEAKNVYSK
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHH
IRVENSIIKPKRGSRMIFFLNSGTIPDEANIAVKTEDGKYVGNLEEDFAEILIPGDIFVL
HHHHCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCCEECCHHHHHHHEEECCCEEEE
SGKTYEFIRSEGNLAIVRSAEGQRPTVPSWFSEMLPLAYDSALEVGKFRGFVANLIEKGI
CCCCEEHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DEKKAIEIISKEYEISKHAAWSIYEYVLEEYLFTNGIVPTDKLILIEIYDDEENRRNFIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCEEE
HALYGRRALDALSRAVAFVVSEELNLDVRVSITDNGFIITIPKIIDYDIKDVLYKLDPNE
EHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEHHHHCCCHHHHHHHCCHHH
LYEILSKVILRTEMIKKRFRHCAERSFMLLRRYKGKETSIDRRQLNSEILLNVVKEYEGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCC
PVLKETIREILEDYMDIEKAIEIVKKVREREIDVKVIGPNRIPSPFAHNIILKEHSDVVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHCCEEEECCCCEEE
AEEKRDLLRKLHDKVIEFLRNKGINIDLKYTEI
EHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8899719; 11427726 [H]