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The map label for this gene is glnA [H]

Identifier: 15921675

GI number: 15921675

Start: 1390703

End: 1392124

Strand: Reverse

Name: glnA [H]

Synonym: ST1387

Alternate gene names: 15921675

Gene position: 1392124-1390703 (Counterclockwise)

Preceding gene: 15921676

Following gene: 15921666

Centisome position: 51.66

GC content: 36.01

Gene sequence:

>1422_bases
ATGCCAAGTTTACCTAAAACAGCCGAAGAGGCTCTGAAATTTCTAAAAGACAATAAAATAAAATGGGTGGATCTACAGTT
TACAGATCTACCTGGAAGATTGCATCATATTACAGTCCCAGCCTCAGAATTTACAGAAGATTCATTTAAAACAGGGTTTG
GAAAATTAGATGGAAGTAGTATAAAAGGATTTACTATGATTTATGAAAGCGATATGGTGCTAATGCCCATACCACAAACT
ATGGCAGTTATACCTTGGAATGAAGGAATTGCTAGAGTTATAACCCAGGTATTTTGGGGAGGAGGAAAGGGAAGATTCGA
GAGAGATCCAAGACATATTGCAGAAGAAGCAGAAAAGAAACAATCAGAAGAAGGTTATATTAGTTATTTTGGCCCAGAGC
TAGAATTCTTTATATTTGATAAAGTAGATTTGGATGTAGCCACACCTCAAAGCGGAACTGGATATAAAATACATGCTAGA
GAAGCCCCATGGGCTAGAAATGGAGGGTTCCTAATAAGATACAAAGAGGGTTATTATCCAGCACCACCTGTAGATCAGCT
AATGGATATAAGAGTCGAGGCTATTAATATATTAACTGATTACTTTGGATTCAATATAGAAGCTACTCACCATGAAGTTG
CTACAGCTGGACAAGGCGAAATTGATTTCAGATTCTCTACATTAGCTGATACAGCCGATAAAGTTCAAACACTAAAATAT
GTCGTAAAAAATGTAGCAGCAAAGCATGGAATGATAGCCACTTTTATGCCAAAACCAATGTTTGGAGATAATGGGACAGG
AATGCATACGCATTTTAGTCTATGGACAAAAGATGGAAAGAATCTAATGTACGATCCTAACGATGAATATGCTGAGTTAA
GTCAAATAGGTAGATATATAGTAGGAGGAATATTAGAACATGGTAGAGCATTATCAGCAATAGTATCGCCAACCACAAAT
AGTTATAGAAGATTAATTCCAGGTTATGAGGCACCCGTATATCTAGTGTGGAGTAAATCCAACAGAAGTGCTGCAATTAG
AATACCATCATATTATAGAGGAATGGAAAAAGCAAAGAGATTAGAATATAGACCACCAGATCCCTCGTGTAACCCATACT
TGGCATTCGCTGCAATACTAATGGCTGCTTTAGATGGAATAAAGAAAAAGATTGAGCCTGGTGATCCTGTTGATGAAAAT
GTATATCATATGAGCGAAGAGAGGAAAAAACAGTTAAAAATTAAGGAATTACCTAGATCATTAGATGAAGCATTAGATGA
GTTAGAAAGCGACAATGAGTTCCTAAAACCAGTATTTAATTCATCAATATTAAATACATACATTGACCTAAAGAGAGACG
AAGCAAAAACTATGCAACAGTATCCTCATCCTATGGAGTTATATTACTATTTAGATGCCTAA

Upstream 100 bases:

>100_bases
CATTTGCATAATCTGTAATTAAGAATTATATATAAACTTCTGAACAGTTTTTATATCTAACACTAATAATCTTTTTAAAC
AATTAAAGCTATTCGTAATC

Downstream 100 bases:

>100_bases
AATTCCAATTTTTCTCAAGTTTCTTCTTATTTCATTTAAATCTAAATAGTAATCGAAAACATAATTTTTTACTGAATCAG
AAAGGATAGAATAGTTAATA

Product: glutamine synthetase

Products: NA

Alternate protein names: GS; Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MPSLPKTAEEALKFLKDNKIKWVDLQFTDLPGRLHHITVPASEFTEDSFKTGFGKLDGSSIKGFTMIYESDMVLMPIPQT
MAVIPWNEGIARVITQVFWGGGKGRFERDPRHIAEEAEKKQSEEGYISYFGPELEFFIFDKVDLDVATPQSGTGYKIHAR
EAPWARNGGFLIRYKEGYYPAPPVDQLMDIRVEAINILTDYFGFNIEATHHEVATAGQGEIDFRFSTLADTADKVQTLKY
VVKNVAAKHGMIATFMPKPMFGDNGTGMHTHFSLWTKDGKNLMYDPNDEYAELSQIGRYIVGGILEHGRALSAIVSPTTN
SYRRLIPGYEAPVYLVWSKSNRSAAIRIPSYYRGMEKAKRLEYRPPDPSCNPYLAFAAILMAALDGIKKKIEPGDPVDEN
VYHMSEERKKQLKIKELPRSLDEALDELESDNEFLKPVFNSSILNTYIDLKRDEAKTMQQYPHPMELYYYLDA

Sequences:

>Translated_473_residues
MPSLPKTAEEALKFLKDNKIKWVDLQFTDLPGRLHHITVPASEFTEDSFKTGFGKLDGSSIKGFTMIYESDMVLMPIPQT
MAVIPWNEGIARVITQVFWGGGKGRFERDPRHIAEEAEKKQSEEGYISYFGPELEFFIFDKVDLDVATPQSGTGYKIHAR
EAPWARNGGFLIRYKEGYYPAPPVDQLMDIRVEAINILTDYFGFNIEATHHEVATAGQGEIDFRFSTLADTADKVQTLKY
VVKNVAAKHGMIATFMPKPMFGDNGTGMHTHFSLWTKDGKNLMYDPNDEYAELSQIGRYIVGGILEHGRALSAIVSPTTN
SYRRLIPGYEAPVYLVWSKSNRSAAIRIPSYYRGMEKAKRLEYRPPDPSCNPYLAFAAILMAALDGIKKKIEPGDPVDEN
VYHMSEERKKQLKIKELPRSLDEALDELESDNEFLKPVFNSSILNTYIDLKRDEAKTMQQYPHPMELYYYLDA
>Mature_472_residues
PSLPKTAEEALKFLKDNKIKWVDLQFTDLPGRLHHITVPASEFTEDSFKTGFGKLDGSSIKGFTMIYESDMVLMPIPQTM
AVIPWNEGIARVITQVFWGGGKGRFERDPRHIAEEAEKKQSEEGYISYFGPELEFFIFDKVDLDVATPQSGTGYKIHARE
APWARNGGFLIRYKEGYYPAPPVDQLMDIRVEAINILTDYFGFNIEATHHEVATAGQGEIDFRFSTLADTADKVQTLKYV
VKNVAAKHGMIATFMPKPMFGDNGTGMHTHFSLWTKDGKNLMYDPNDEYAELSQIGRYIVGGILEHGRALSAIVSPTTNS
YRRLIPGYEAPVYLVWSKSNRSAAIRIPSYYRGMEKAKRLEYRPPDPSCNPYLAFAAILMAALDGIKKKIEPGDPVDENV
YHMSEERKKQLKIKELPRSLDEALDELESDNEFLKPVFNSSILNTYIDLKRDEAKTMQQYPHPMELYYYLDA

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=466, Percent_Identity=25.9656652360515, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1790301, Length=477, Percent_Identity=46.1215932914046, Blast_Score=391, Evalue=1e-110,
Organism=Escherichia coli, GI87081870, Length=369, Percent_Identity=26.0162601626016, Blast_Score=113, Evalue=3e-26,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 53767; Mature: 53636

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS00180 GLNA_1 ; PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLPKTAEEALKFLKDNKIKWVDLQFTDLPGRLHHITVPASEFTEDSFKTGFGKLDGSS
CCCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEECCHHHHCCHHHHCCCCCCCCCC
IKGFTMIYESDMVLMPIPQTMAVIPWNEGIARVITQVFWGGGKGRFERDPRHIAEEAEKK
CCCEEEEEECCEEEEECCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
QSEEGYISYFGPELEFFIFDKVDLDVATPQSGTGYKIHAREAPWARNGGFLIRYKEGYYP
CCCCCCEEEECCCEEEEEEEEEEEEEECCCCCCCEEEEECCCCCCCCCCEEEEECCCCCC
APPVDQLMDIRVEAINILTDYFGFNIEATHHEVATAGQGEIDFRFSTLADTADKVQTLKY
CCCHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHCCCCCCEEEEEHHHHHHHHHHHHHHH
VVKNVAAKHGMIATFMPKPMFGDNGTGMHTHFSLWTKDGKNLMYDPNDEYAELSQIGRYI
HHHHHHHHCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
VGGILEHGRALSAIVSPTTNSYRRLIPGYEAPVYLVWSKSNRSAAIRIPSYYRGMEKAKR
HHHHHHCCCCEEEEECCCCHHHHHHCCCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHH
LEYRPPDPSCNPYLAFAAILMAALDGIKKKIEPGDPVDENVYHMSEERKKQLKIKELPRS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHH
LDEALDELESDNEFLKPVFNSSILNTYIDLKRDEAKTMQQYPHPMELYYYLDA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEECC
>Mature Secondary Structure 
PSLPKTAEEALKFLKDNKIKWVDLQFTDLPGRLHHITVPASEFTEDSFKTGFGKLDGSS
CCCCHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEECCHHHHCCHHHHCCCCCCCCCC
IKGFTMIYESDMVLMPIPQTMAVIPWNEGIARVITQVFWGGGKGRFERDPRHIAEEAEKK
CCCEEEEEECCEEEEECCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
QSEEGYISYFGPELEFFIFDKVDLDVATPQSGTGYKIHAREAPWARNGGFLIRYKEGYYP
CCCCCCEEEECCCEEEEEEEEEEEEEECCCCCCCEEEEECCCCCCCCCCEEEEECCCCCC
APPVDQLMDIRVEAINILTDYFGFNIEATHHEVATAGQGEIDFRFSTLADTADKVQTLKY
CCCHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHCCCCCCEEEEEHHHHHHHHHHHHHHH
VVKNVAAKHGMIATFMPKPMFGDNGTGMHTHFSLWTKDGKNLMYDPNDEYAELSQIGRYI
HHHHHHHHCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
VGGILEHGRALSAIVSPTTNSYRRLIPGYEAPVYLVWSKSNRSAAIRIPSYYRGMEKAKR
HHHHHHCCCCEEEEECCCCHHHHHHCCCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHH
LEYRPPDPSCNPYLAFAAILMAALDGIKKKIEPGDPVDENVYHMSEERKKQLKIKELPRS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHH
LDEALDELESDNEFLKPVFNSSILNTYIDLKRDEAKTMQQYPHPMELYYYLDA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9865608 [H]