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The map label for this gene is ygeZ [C]

Identifier: 15921257

GI number: 15921257

Start: 993505

End: 994806

Strand: Reverse

Name: ygeZ [C]

Synonym: ST1011

Alternate gene names: 15921257

Gene position: 994806-993505 (Counterclockwise)

Preceding gene: 15921265

Following gene: 15921256

Centisome position: 36.92

GC content: 30.95

Gene sequence:

>1302_bases
ATGATATTTAAAAATGCTAGGGTAATAACACCTAAAGGAATTATTGAAACAGATTTTGAGGTTGAAGAAGGAAAAATTAA
GAAAATTAAGAAGGATATAGTAGGTGAAGGAAAAGACTTATCTGGTTATTATGTACTGCCTAGTGTAATTGATGGACATA
CGCATTTTAACTCAAGATATTTAGGGGCTAAAGAAATAATTCCCACGGCAGATGATTATAAAAGTGGTAGTGAAATAACA
TTAGCAGGCGGAATAACTTCTATAATAAACTTTATTGATCCTTTAAATAGAGAAGTAACAGAGGCAGTTAAAGATGAGAT
AGAAAAAGCTAAAAGTACTGCTGGTATTGATTATTCCTTTCATTTAATTATTAAAAGAAAAGATCAGATTAATTATTTAC
CAGAAATTATTAAAATGGGTATAAAAAGCATAAAAATGTTCATGGCATATAAGGGAAGTATGCAAGTTGATGATGAAACA
ATATATCTTGTCATGAAGAAAGCTAAAGAGTTAGGCGTAACTGTTGCAATCCATGCTGAGAACGGCGATGTTATAGAGGT
CTTACACAATGAGTACAAAGATAAGAAAGATGCAATATATCATGCACTTACAAGACCAGTAGAAGTTGAGGAAGAAGCCG
TTAATAGGGCTTCTATGTTAGCTTATTTAACTGGCGCTAAAACTTATATTGTTCATATTTCTTCTCCTACATCTCTAGAT
ATAATATCTTATTGGAGAAAGAAGGGAGCTAAAATTTTCAGCGAGACTTGTCCACATTACCTTTTATTTGACGATAGTTA
TTATCTAAGATCAGATGGAAATAGATTTATAATGTCACCTCCATTGAGAAGAAAAGAATTAAGAGAAGAACTTGTAAGAA
AACTTCACATGGTAAATACTTTAGGAAGTGATTACTCTGGTTTTATGTCTGTTTATAAGGATAAGGCATTAAGCTACATT
GAAGTTCCAAATGGTGTATCTTCAACAGAATTTTTAGTCCCTACAATTATGTCTTTTCTTTTTGACAATTTAATAACACC
AGAAAAAGTTGCTGAAATAACTTCTTATAACCAGATAAAACTTTATAACTTAAAAGAAAAAGGATTCGATGAAGGAAAAG
ATGCCGATTTTACAGTTATAAAGAGAGAAGAATGGATTGTAAAAGATTGGCACGGTAAGATGGATTACTCAATTTACGAG
GGAGTAAAATTCAAAGCAAAAGTTATTCAAACTTACTTGAGAGGTGAATTAACCTTTGATGAGGATTATAAAGGTAGTAG
AGGAAAATTATTGAAAAGATAA

Upstream 100 bases:

>100_bases
AAATATTTTAGGGTGATTTAAATAGATTTATGCCCATTATATAAATTCTATAATTAGATAAAAAATAATGTTTATATTAC
TCCATTAAGATACACCTTAT

Downstream 100 bases:

>100_bases
ACAGTGTAGTTTTTTATAATGATAGTTTTTGATGTTAAAATAAAATCTATTCAGTAGGTTATGGCTATCTATGAATACTT
TTTAATTTAATTGTTTAATT

Product: D-hydantoinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MIFKNARVITPKGIIETDFEVEEGKIKKIKKDIVGEGKDLSGYYVLPSVIDGHTHFNSRYLGAKEIIPTADDYKSGSEIT
LAGGITSIINFIDPLNREVTEAVKDEIEKAKSTAGIDYSFHLIIKRKDQINYLPEIIKMGIKSIKMFMAYKGSMQVDDET
IYLVMKKAKELGVTVAIHAENGDVIEVLHNEYKDKKDAIYHALTRPVEVEEEAVNRASMLAYLTGAKTYIVHISSPTSLD
IISYWRKKGAKIFSETCPHYLLFDDSYYLRSDGNRFIMSPPLRRKELREELVRKLHMVNTLGSDYSGFMSVYKDKALSYI
EVPNGVSSTEFLVPTIMSFLFDNLITPEKVAEITSYNQIKLYNLKEKGFDEGKDADFTVIKREEWIVKDWHGKMDYSIYE
GVKFKAKVIQTYLRGELTFDEDYKGSRGKLLKR

Sequences:

>Translated_433_residues
MIFKNARVITPKGIIETDFEVEEGKIKKIKKDIVGEGKDLSGYYVLPSVIDGHTHFNSRYLGAKEIIPTADDYKSGSEIT
LAGGITSIINFIDPLNREVTEAVKDEIEKAKSTAGIDYSFHLIIKRKDQINYLPEIIKMGIKSIKMFMAYKGSMQVDDET
IYLVMKKAKELGVTVAIHAENGDVIEVLHNEYKDKKDAIYHALTRPVEVEEEAVNRASMLAYLTGAKTYIVHISSPTSLD
IISYWRKKGAKIFSETCPHYLLFDDSYYLRSDGNRFIMSPPLRRKELREELVRKLHMVNTLGSDYSGFMSVYKDKALSYI
EVPNGVSSTEFLVPTIMSFLFDNLITPEKVAEITSYNQIKLYNLKEKGFDEGKDADFTVIKREEWIVKDWHGKMDYSIYE
GVKFKAKVIQTYLRGELTFDEDYKGSRGKLLKR
>Mature_433_residues
MIFKNARVITPKGIIETDFEVEEGKIKKIKKDIVGEGKDLSGYYVLPSVIDGHTHFNSRYLGAKEIIPTADDYKSGSEIT
LAGGITSIINFIDPLNREVTEAVKDEIEKAKSTAGIDYSFHLIIKRKDQINYLPEIIKMGIKSIKMFMAYKGSMQVDDET
IYLVMKKAKELGVTVAIHAENGDVIEVLHNEYKDKKDAIYHALTRPVEVEEEAVNRASMLAYLTGAKTYIVHISSPTSLD
IISYWRKKGAKIFSETCPHYLLFDDSYYLRSDGNRFIMSPPLRRKELREELVRKLHMVNTLGSDYSGFMSVYKDKALSYI
EVPNGVSSTEFLVPTIMSFLFDNLITPEKVAEITSYNQIKLYNLKEKGFDEGKDADFTVIKREEWIVKDWHGKMDYSIYE
GVKFKAKVIQTYLRGELTFDEDYKGSRGKLLKR

Specific function: Catalyzes the stereospecific hydrolysis of the cyclic amide bond of D-hydantoin. Has no activity on dihydropyrimidines [H]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503379, Length=450, Percent_Identity=28, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI4503375, Length=457, Percent_Identity=29.1028446389497, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI4503377, Length=450, Percent_Identity=27.7777777777778, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI190194363, Length=456, Percent_Identity=26.9736842105263, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI4503051, Length=451, Percent_Identity=27.2727272727273, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI62422571, Length=450, Percent_Identity=26.8888888888889, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI19923821, Length=456, Percent_Identity=26.7543859649123, Blast_Score=135, Evalue=8e-32,
Organism=Escherichia coli, GI87082175, Length=462, Percent_Identity=29.6536796536797, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1786722, Length=447, Percent_Identity=27.9642058165548, Blast_Score=143, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71989490, Length=451, Percent_Identity=29.0465631929047, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI17539558, Length=454, Percent_Identity=30.1762114537445, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI86575075, Length=457, Percent_Identity=22.9759299781182, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322218, Length=423, Percent_Identity=21.9858156028369, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17137462, Length=447, Percent_Identity=29.5302013422819, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI221377917, Length=459, Percent_Identity=29.6296296296296, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24644287, Length=321, Percent_Identity=30.5295950155763, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24644289, Length=236, Percent_Identity=32.6271186440678, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24642586, Length=383, Percent_Identity=22.1932114882507, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011778
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: 3.-.-.- [C]

Molecular weight: Translated: 49520; Mature: 49520

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFKNARVITPKGIIETDFEVEEGKIKKIKKDIVGEGKDLSGYYVLPSVIDGHTHFNSRY
CCCCCCEEECCCCCEECCCCCCCCHHHHHHHHHCCCCCCCCCEEEECHHHCCCCCCCCCC
LGAKEIIPTADDYKSGSEITLAGGITSIINFIDPLNREVTEAVKDEIEKAKSTAGIDYSF
CCHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEE
HLIIKRKDQINYLPEIIKMGIKSIKMFMAYKGSMQVDDETIYLVMKKAKELGVTVAIHAE
EEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCEEEEEEHHHHHCCEEEEEECC
NGDVIEVLHNEYKDKKDAIYHALTRPVEVEEEAVNRASMLAYLTGAKTYIVHISSPTSLD
CCCCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCEEEEEEECCCCCHH
IISYWRKKGAKIFSETCPHYLLFDDSYYLRSDGNRFIMSPPLRRKELREELVRKLHMVNT
HHHHHHHHCCHHHHHCCCCEEEECCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHH
LGSDYSGFMSVYKDKALSYIEVPNGVSSTEFLVPTIMSFLFDNLITPEKVAEITSYNQIK
CCCCHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEE
LYNLKEKGFDEGKDADFTVIKREEWIVKDWHGKMDYSIYEGVKFKAKVIQTYLRGELTFD
EEECHHCCCCCCCCCCEEEEECCCCEEECCCCCCCCHHHCCCHHHHHHHHHHHCCCCEEC
EDYKGSRGKLLKR
CCCCCCCCCCCCC
>Mature Secondary Structure
MIFKNARVITPKGIIETDFEVEEGKIKKIKKDIVGEGKDLSGYYVLPSVIDGHTHFNSRY
CCCCCCEEECCCCCEECCCCCCCCHHHHHHHHHCCCCCCCCCEEEECHHHCCCCCCCCCC
LGAKEIIPTADDYKSGSEITLAGGITSIINFIDPLNREVTEAVKDEIEKAKSTAGIDYSF
CCHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEE
HLIIKRKDQINYLPEIIKMGIKSIKMFMAYKGSMQVDDETIYLVMKKAKELGVTVAIHAE
EEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCEEEEEEHHHHHCCEEEEEECC
NGDVIEVLHNEYKDKKDAIYHALTRPVEVEEEAVNRASMLAYLTGAKTYIVHISSPTSLD
CCCCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCEEEEEEECCCCCHH
IISYWRKKGAKIFSETCPHYLLFDDSYYLRSDGNRFIMSPPLRRKELREELVRKLHMVNT
HHHHHHHHCCHHHHHCCCCEEEECCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHH
LGSDYSGFMSVYKDKALSYIEVPNGVSSTEFLVPTIMSFLFDNLITPEKVAEITSYNQIK
CCCCHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEE
LYNLKEKGFDEGKDADFTVIKREEWIVKDWHGKMDYSIYEGVKFKAKVIQTYLRGELTFD
EEECHHCCCCCCCCCCEEEEECCCCEEECCCCCCCCHHHCCCHHHHHHHHHHHCCCCEEC
EDYKGSRGKLLKR
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7765480 [H]