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The map label for this gene is pcnC

Identifier: 15921180

GI number: 15921180

Start: 919403

End: 920143

Strand: Reverse

Name: pcnC

Synonym: ST0944

Alternate gene names: 15921180

Gene position: 920143-919403 (Counterclockwise)

Preceding gene: 15921181

Following gene: 15921179

Centisome position: 34.15

GC content: 33.06

Gene sequence:

>741_bases
ATGAGAGTTAAAGTTATTGACGCAGATGCTTTTTCATATATTTTTAGAACATTAGAGGAATTTATTGATGAAATAACACT
TGATTTTACCTCAGATGGACTAAAAATTAGGGGTATTGATCCTTCTAGGGTTACTTTTATTGATATTTTAATTCCTGCCG
GTTATTTTGAGGAATATAATGTAGAGAAGGAAGAAAAAGTAGGAGTAAAATTAGAGGATTTTACTGATGTATTAAAGACT
GTTACAAAGAACGATAGCTTGTACTTAGAAACAGATGAAAATCAAAACATAAAAGTTACTCTTGATGGTGTATATGAAAG
AACATTTACTTTTCCATCAATAGTTGCTTCTGAGATAGAAACTCCAAATTTAAACCTAGAATTTCCATTTAAGGCAAAGG
CTCTTACAGTCACATTTACGGATATAATAGATGAAATAGAAGATATAGGCGGAGACTCAATTACATTTAAAGCTGAAGGA
GGAAAACTATACCTTTCTGCAAATTCAGACATGGGATCTTCTACTATAGAATTGTCAACAGAGAATGGAGGCCTTTTAGA
AAGCGAAGGAGGAGATGCAGAGAGTGTATATGGACTTGAGTATGTAGTAAATACGTCAAAAATGAGAAAACCTTCAGATA
CTGTTGAGATAGCCTTTGGATCGCAAATACCATTGAAACTAAGATATAATTTACCTCAAGGGGGGTATGCAGATTTCTAC
ATTGCACCAAGAGCAGAATAA

Upstream 100 bases:

>100_bases
TTTATGCTGAACTCCAAAGAATATTTGCTGGAGGGGAGGATTACCTAACAGAAGAACCAAGTCCTAAGCTTTAAAACTCT
ATTTCGATAATGACTTATAT

Downstream 100 bases:

>100_bases
GATAATTAAGATTCTTTTTTCAGAATATTATGAGAAAGCTGAGTTAGATTTACCAAATGATATGGAACTAAGAGAATTTG
CATATCAGCCCTTTGATTCT

Product: proliferating cell nuclear antigen

Products: NA

Alternate protein names: Proliferating cell nuclear antigen homolog C; PCNA C

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MRVKVIDADAFSYIFRTLEEFIDEITLDFTSDGLKIRGIDPSRVTFIDILIPAGYFEEYNVEKEEKVGVKLEDFTDVLKT
VTKNDSLYLETDENQNIKVTLDGVYERTFTFPSIVASEIETPNLNLEFPFKAKALTVTFTDIIDEIEDIGGDSITFKAEG
GKLYLSANSDMGSSTIELSTENGGLLESEGGDAESVYGLEYVVNTSKMRKPSDTVEIAFGSQIPLKLRYNLPQGGYADFY
IAPRAE

Sequences:

>Translated_246_residues
MRVKVIDADAFSYIFRTLEEFIDEITLDFTSDGLKIRGIDPSRVTFIDILIPAGYFEEYNVEKEEKVGVKLEDFTDVLKT
VTKNDSLYLETDENQNIKVTLDGVYERTFTFPSIVASEIETPNLNLEFPFKAKALTVTFTDIIDEIEDIGGDSITFKAEG
GKLYLSANSDMGSSTIELSTENGGLLESEGGDAESVYGLEYVVNTSKMRKPSDTVEIAFGSQIPLKLRYNLPQGGYADFY
IAPRAE
>Mature_246_residues
MRVKVIDADAFSYIFRTLEEFIDEITLDFTSDGLKIRGIDPSRVTFIDILIPAGYFEEYNVEKEEKVGVKLEDFTDVLKT
VTKNDSLYLETDENQNIKVTLDGVYERTFTFPSIVASEIETPNLNLEFPFKAKALTVTFTDIIDEIEDIGGDSITFKAEG
GKLYLSANSDMGSSTIELSTENGGLLESEGGDAESVYGLEYVVNTSKMRKPSDTVEIAFGSQIPLKLRYNLPQGGYADFY
IAPRAE

Specific function: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication

COG id: COG0592

COG function: function code L; DNA polymerase sliding clamp subunit (PCNA homolog)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PCNA family

Homologues:

Organism=Homo sapiens, GI33239451, Length=253, Percent_Identity=19.7628458498024, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI4505641, Length=253, Percent_Identity=19.7628458498024, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PCNA3_SULTO (Q973F5)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376849.1
- ProteinModelPortal:   Q973F5
- GeneID:   1458909
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST0944
- NMPDR:   fig|273063.1.peg.1017
- HOGENOM:   HBG553564
- OMA:   DSAREFE
- ProtClustDB:   PRK01115
- BioCyc:   STOK273063:ST0944-MONOMER
- HAMAP:   MF_00317
- InterPro:   IPR000730
- InterPro:   IPR022649
- InterPro:   IPR022659
- InterPro:   IPR022648
- PANTHER:   PTHR11352
- PRINTS:   PR00339

Pfam domain/function: PF02747 PCNA_C; PF00705 PCNA_N

EC number: NA

Molecular weight: Translated: 27437; Mature: 27437

Theoretical pI: Translated: 4.02; Mature: 4.02

Prosite motif: PS01251 PCNA_1; PS00293 PCNA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVKVIDADAFSYIFRTLEEFIDEITLDFTSDGLKIRGIDPSRVTFIDILIPAGYFEEYN
CEEEEEECHHHHHHHHHHHHHHHHEEEEEECCCEEEEECCCCCEEEEEEEECCCCCHHCC
VEKEEKVGVKLEDFTDVLKTVTKNDSLYLETDENQNIKVTLDGVYERTFTFPSIVASEIE
CCHHHHCCCEEHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECEEEEEECCHHHHHHHCC
TPNLNLEFPFKAKALTVTFTDIIDEIEDIGGDSITFKAEGGKLYLSANSDMGSSTIELST
CCCCEEECCCCCEEEEEEHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCCCEEEEEC
ENGGLLESEGGDAESVYGLEYVVNTSKMRKPSDTVEIAFGSQIPLKLRYNLPQGGYADFY
CCCCEEECCCCCCCCEEEEEEEEEHHHCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEE
IAPRAE
EECCCC
>Mature Secondary Structure
MRVKVIDADAFSYIFRTLEEFIDEITLDFTSDGLKIRGIDPSRVTFIDILIPAGYFEEYN
CEEEEEECHHHHHHHHHHHHHHHHEEEEEECCCEEEEECCCCCEEEEEEEECCCCCHHCC
VEKEEKVGVKLEDFTDVLKTVTKNDSLYLETDENQNIKVTLDGVYERTFTFPSIVASEIE
CCHHHHCCCEEHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECEEEEEECCHHHHHHHCC
TPNLNLEFPFKAKALTVTFTDIIDEIEDIGGDSITFKAEGGKLYLSANSDMGSSTIELST
CCCCEEECCCCCEEEEEEHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCCCEEEEEC
ENGGLLESEGGDAESVYGLEYVVNTSKMRKPSDTVEIAFGSQIPLKLRYNLPQGGYADFY
CCCCEEECCCCCCCCEEEEEEEEEHHHCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEE
IAPRAE
EECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479