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The map label for this gene is malP [C]

Identifier: 15921129

GI number: 15921129

Start: 870212

End: 871654

Strand: Direct

Name: malP [C]

Synonym: ST0893

Alternate gene names: 15921129

Gene position: 870212-871654 (Clockwise)

Preceding gene: 15921121

Following gene: 15921131

Centisome position: 32.29

GC content: 33.96

Gene sequence:

>1443_bases
ATGCGGAAACACTTAAAAGGTAAAGCTCATAAGAAATTACACATGATAATCAGTATCACTGCGGAGTTAGGAATTGACTT
TGGTGAGAACTTTGCAGGTGGTTTAGGCGTTCTCGAAGGAGATAAGTTTTATGCCTCAGCAAGATTAGGAATTGATTACA
CTGTCTTTACATTATTTTATAGAAAAGGATATACTGGAAATGAGGAGAAACAGAAAGAATTGCTTAAAAATCTTGTTAAA
GAATGGGAGACTGAAATAGAACTTAAAAAGGGTAAAATAAAGATCGAATACTTAACGTATAAACTTAATACTGCAAAAGC
TATATTTATTAACATTTTATCACCAGATTGGGCTAAAAGACTTAACGAGAAACTTTACATTGAGAATTCTGAAGAAGATA
GATTTTACAAATATTTAGTCCTTGCTAAAGCAACTGAGAAATACATTAGTGAGAAGATAGGTTGGGATAAGATAAAATAT
GTTGACTTGCAAGAAGCCTATCCGTCTTTCTTACCATTATTAAAATATTTTCCTAGATACAGAATAATAATACACACACC
AGCACCGTGGGGTCATCCCACATTTCCTGCAAGATATTTCAAAGAAGAATTTGGCTTTGAATTTCCCTTTGATCCAGTTG
TTATGACTGAAATAGGATTATCTTCAGCCGTGCAAGGAATAGTAGTCTCAAAAAAGATGCTTCATCACGTAAGCAAAACA
TTTCCACATCATATGCATAAAATAAAGGCTATAACGAATGCTGTTGAAATACCCAGATGGAGACATCCATTATTAAATAA
CGTCAAAGATCTTGATGATTTTATCAAGAAGAAAAAAGAAGTGAAAAAAGAGAGTTTAAAGAAACTAGGAAAGGAGAGTG
ATAAACCCACAATAGGCTGGGTAAGGAGAATAACTCAATATAAAAGACCAGAATTCATATTAAGATTAATTGACGAATTA
AGGGATGATGTCGTTTTTATAATTGGTGGAAAGGCTCATCCATATGAGTATTATGGTGTAGAATTAGAGAAAAAGTTTAA
GGAATATGCTCAAAAAAGAAATAATGTAATTTACGTTCAGGGGGTGGATATACAGCAAATGAAATTAGCAATATGGTCTA
GTGACATATGGACCTTTACACCTTATTCTGGATGGGAGGCTAGTGGAACAAGTTTTATGAAGGCTGGAGTGAATGGAGTT
CCTTCTGTAGCATCAAGAGACGGTGCCGTACCAGAGATTATTAAGGATGGATATAATGGTTGGCTTTATGGAGAAGATAG
ATACGAGCTTCTACCAGTAGACACATATGATAGGGAATATGAGGAATTCGCAAGAAAGGTGAAGGAGGCTTTAAACAAGT
ATTATGAAGTTGGCTATAATGCTTATCATACTTTTTCCGATTTTTGTTCTATGGATAGACTTATGAAAGAATACGCTTTA
TAA

Upstream 100 bases:

>100_bases
TGTCTATTTTGTTCCTATCCACAATTTAACCTTAGATCTTGGGATAAAAAATTTTTCAGTACCAAACTGTAATAAAAATT
ATTTTGCAAAAATTATTTGT

Downstream 100 bases:

>100_bases
GCCATACTAAAGCTATGACTAAAACTAATATAATGCAAAGATTTACATAATTTATACCTATTATTTCTTTCTCCACTATA
GGAGAAGTAACTTCAACTGT

Product: hypothetical protein

Products: (1,4-alpha-D-glucosyl)n-1; alpha-D-glucose 1-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MRKHLKGKAHKKLHMIISITAELGIDFGENFAGGLGVLEGDKFYASARLGIDYTVFTLFYRKGYTGNEEKQKELLKNLVK
EWETEIELKKGKIKIEYLTYKLNTAKAIFINILSPDWAKRLNEKLYIENSEEDRFYKYLVLAKATEKYISEKIGWDKIKY
VDLQEAYPSFLPLLKYFPRYRIIIHTPAPWGHPTFPARYFKEEFGFEFPFDPVVMTEIGLSSAVQGIVVSKKMLHHVSKT
FPHHMHKIKAITNAVEIPRWRHPLLNNVKDLDDFIKKKKEVKKESLKKLGKESDKPTIGWVRRITQYKRPEFILRLIDEL
RDDVVFIIGGKAHPYEYYGVELEKKFKEYAQKRNNVIYVQGVDIQQMKLAIWSSDIWTFTPYSGWEASGTSFMKAGVNGV
PSVASRDGAVPEIIKDGYNGWLYGEDRYELLPVDTYDREYEEFARKVKEALNKYYEVGYNAYHTFSDFCSMDRLMKEYAL

Sequences:

>Translated_480_residues
MRKHLKGKAHKKLHMIISITAELGIDFGENFAGGLGVLEGDKFYASARLGIDYTVFTLFYRKGYTGNEEKQKELLKNLVK
EWETEIELKKGKIKIEYLTYKLNTAKAIFINILSPDWAKRLNEKLYIENSEEDRFYKYLVLAKATEKYISEKIGWDKIKY
VDLQEAYPSFLPLLKYFPRYRIIIHTPAPWGHPTFPARYFKEEFGFEFPFDPVVMTEIGLSSAVQGIVVSKKMLHHVSKT
FPHHMHKIKAITNAVEIPRWRHPLLNNVKDLDDFIKKKKEVKKESLKKLGKESDKPTIGWVRRITQYKRPEFILRLIDEL
RDDVVFIIGGKAHPYEYYGVELEKKFKEYAQKRNNVIYVQGVDIQQMKLAIWSSDIWTFTPYSGWEASGTSFMKAGVNGV
PSVASRDGAVPEIIKDGYNGWLYGEDRYELLPVDTYDREYEEFARKVKEALNKYYEVGYNAYHTFSDFCSMDRLMKEYAL
>Mature_480_residues
MRKHLKGKAHKKLHMIISITAELGIDFGENFAGGLGVLEGDKFYASARLGIDYTVFTLFYRKGYTGNEEKQKELLKNLVK
EWETEIELKKGKIKIEYLTYKLNTAKAIFINILSPDWAKRLNEKLYIENSEEDRFYKYLVLAKATEKYISEKIGWDKIKY
VDLQEAYPSFLPLLKYFPRYRIIIHTPAPWGHPTFPARYFKEEFGFEFPFDPVVMTEIGLSSAVQGIVVSKKMLHHVSKT
FPHHMHKIKAITNAVEIPRWRHPLLNNVKDLDDFIKKKKEVKKESLKKLGKESDKPTIGWVRRITQYKRPEFILRLIDEL
RDDVVFIIGGKAHPYEYYGVELEKKFKEYAQKRNNVIYVQGVDIQQMKLAIWSSDIWTFTPYSGWEASGTSFMKAGVNGV
PSVASRDGAVPEIIKDGYNGWLYGEDRYELLPVDTYDREYEEFARKVKEALNKYYEVGYNAYHTFSDFCSMDRLMKEYAL

Specific function: Phosphorylase Is An Important Allosteric Enzyme In Carbohydrate Metabolism. Enzymes From Different Sources Differ In Their Regulatory Mechanisms And In Their Natural Substrates. However, All Known Phosphorylases Share Catalytic And Structural Properties.

COG id: COG0058

COG function: function code G; Glucan phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycogen phosphorylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011834
- InterPro:   IPR000811 [H]

Pfam domain/function: PF00343 Phosphorylase [H]

EC number: 2.4.1.1

Molecular weight: Translated: 56198; Mature: 56198

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKHLKGKAHKKLHMIISITAELGIDFGENFAGGLGVLEGDKFYASARLGIDYTVFTLFY
CCCCCCCCHHHHEEEEEEEEHHHCCCCCCCCCCCCCEECCCCEEEEEECCCHHHHHHHHH
RKGYTGNEEKQKELLKNLVKEWETEIELKKGKIKIEYLTYKLNTAKAIFINILSPDWAKR
HCCCCCCHHHHHHHHHHHHHHHHHHEEEECCEEEEEEEEEEECCCEEEEEEECCCHHHHH
LNEKLYIENSEEDRFYKYLVLAKATEKYISEKIGWDKIKYVDLQEAYPSFLPLLKYFPRY
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCCE
RIIIHTPAPWGHPTFPARYFKEEFGFEFPFDPVVMTEIGLSSAVQGIVVSKKMLHHVSKT
EEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHH
FPHHMHKIKAITNAVEIPRWRHPLLNNVKDLDDFIKKKKEVKKESLKKLGKESDKPTIGW
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
VRRITQYKRPEFILRLIDELRDDVVFIIGGKAHPYEYYGVELEKKFKEYAQKRNNVIYVQ
HHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCCCCCEECCHHHHHHHHHHHHCCCEEEEE
GVDIQQMKLAIWSSDIWTFTPYSGWEASGTSFMKAGVNGVPSVASRDGAVPEIIKDGYNG
CCCHHHHHHEEECCCCEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHCCCCC
WLYGEDRYELLPVDTYDREYEEFARKVKEALNKYYEVGYNAYHTFSDFCSMDRLMKEYAL
EEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKHLKGKAHKKLHMIISITAELGIDFGENFAGGLGVLEGDKFYASARLGIDYTVFTLFY
CCCCCCCCHHHHEEEEEEEEHHHCCCCCCCCCCCCCEECCCCEEEEEECCCHHHHHHHHH
RKGYTGNEEKQKELLKNLVKEWETEIELKKGKIKIEYLTYKLNTAKAIFINILSPDWAKR
HCCCCCCHHHHHHHHHHHHHHHHHHEEEECCEEEEEEEEEEECCCEEEEEEECCCHHHHH
LNEKLYIENSEEDRFYKYLVLAKATEKYISEKIGWDKIKYVDLQEAYPSFLPLLKYFPRY
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCCE
RIIIHTPAPWGHPTFPARYFKEEFGFEFPFDPVVMTEIGLSSAVQGIVVSKKMLHHVSKT
EEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHH
FPHHMHKIKAITNAVEIPRWRHPLLNNVKDLDDFIKKKKEVKKESLKKLGKESDKPTIGW
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
VRRITQYKRPEFILRLIDELRDDVVFIIGGKAHPYEYYGVELEKKFKEYAQKRNNVIYVQ
HHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCCCCCEECCHHHHHHHHHHHHCCCEEEEE
GVDIQQMKLAIWSSDIWTFTPYSGWEASGTSFMKAGVNGVPSVASRDGAVPEIIKDGYNG
CCCHHHHHHEEECCCCEEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHCCCCC
WLYGEDRYELLPVDTYDREYEEFARKVKEALNKYYEVGYNAYHTFSDFCSMDRLMKEYAL
EEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: 5'-AMP [C]

Metal ions: CNO- [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 2.7 {glucose} 1 {glucose} [C]

Substrates: (1,4-alpha-D-glucosyl)n; phosphate

Specific reaction: (1,4-alpha-D-glucosyl)n + phosphate = (1,4-alpha-D-glucosyl)n-1 + alpha-D-glucose 1-phosphate

General reaction: Hexosyl group transfer [C]

Inhibitor: ADP glucose; Ag2+; alpha-Amylose; beta-Amylose; Ca2+; CN-; Cu2+; Fe2+; Glucose; Glucose1-phosphate substrate inhibition; Hg2+; IAA; Iodoacetate; K2S2O8; KNO3; NEM; PCMB; TDP glucose; Zn2+ [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]