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The map label for this gene is hpaG [H]

Identifier: 15920957

GI number: 15920957

Start: 711226

End: 712107

Strand: Direct

Name: hpaG [H]

Synonym: ST0727

Alternate gene names: 15920957

Gene position: 711226-712107 (Clockwise)

Preceding gene: 15920956

Following gene: 15920960

Centisome position: 26.39

GC content: 33.45

Gene sequence:

>882_bases
GTGTTATTCCGTTTGACAAAGTTTTTATCTTTTTTAGTTAATAACACTAGAAAGTTAGGAATTCTAAATGGAAATTATAT
ATATGAAGTGAAGGATTTTTATTCTACTGAGCCTAAAGGCGAGGCTTATAAAATTGATGAAATAGAGTTTGACATACCAG
TTATGCCATCAGCGATCATTTGCACACTAGTAAATACTCCGGGAATGATAGGGGTTAAGGATAAAAGTGAAGCAAGAGAA
TTTATAAAATCTCCGAAGTTCTTTCTTAAATTACCCTCTGTAGCAATTCCTCATAAAAAACCAATTATAACTCCTAAAGA
TGCAATAAGACCAGAAGTAGAAATTGGCGTAATTACAAGAAAAATAAAGAGAGGTGCTACGCTTAACGAAATTAAGAAAA
ACATAATTGGTTATACAGTATTTAACGATATAACGTACCCGCCGGGAATAAAGGAAGATTCTTATTACGCATACAGAAGA
GATCCTTCAGACGGGAAAGTTAAAAAACTACTAATCAGAGGAACTCATTTCAGAAACAAGGTAAGGGACTCTTTTGCTCC
ATTCGGACCATGGATAGTTACACCAGAAGAGATCGATGATGTTAACTCACTAGAAATGAAGAGTTACTACGATGGAAAAT
TGGTACAAGAAGGCAATTCTGAGGATTTTGTCTTTTCCATAGAAGAGATTATATTGGAACTAACAAAGTATGTAACTTTA
CCAGAGTTCTCACTAATATCATCTGGAAGTGTAGGATATATAGGTGCTGAAGAAGTATCAGAGTTCTCACTAAAACCAAT
TAACAATGCAATTATGGTTGCTGAAGTTGAAAAGATAGGTAAACTTGAAAATCCTACTATAATTGATGAGAATAACGTTT
AA

Upstream 100 bases:

>100_bases
TGGGCACAGACATATACAGAGGTATTTAAAGATAGGAAAAATGAATTTGTAAAATTAGTTAAAGAAATAATGGATCAAAT
GCCAAATCCTAAAGCATAAG

Downstream 100 bases:

>100_bases
TAACTAGAGCACCTATTACTGTAGTCAGAATTGACATGAAAACTATACTCTCAAACTCATTTTGATCTAAAGCGTTTAGA
CTTAAACCTATTGATGCTAC

Product: hypothetical protein

Products: NA

Alternate protein names: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; HHDD isomerase; 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase; 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; OPET decarboxylase [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MLFRLTKFLSFLVNNTRKLGILNGNYIYEVKDFYSTEPKGEAYKIDEIEFDIPVMPSAIICTLVNTPGMIGVKDKSEARE
FIKSPKFFLKLPSVAIPHKKPIITPKDAIRPEVEIGVITRKIKRGATLNEIKKNIIGYTVFNDITYPPGIKEDSYYAYRR
DPSDGKVKKLLIRGTHFRNKVRDSFAPFGPWIVTPEEIDDVNSLEMKSYYDGKLVQEGNSEDFVFSIEEIILELTKYVTL
PEFSLISSGSVGYIGAEEVSEFSLKPINNAIMVAEVEKIGKLENPTIIDENNV

Sequences:

>Translated_293_residues
MLFRLTKFLSFLVNNTRKLGILNGNYIYEVKDFYSTEPKGEAYKIDEIEFDIPVMPSAIICTLVNTPGMIGVKDKSEARE
FIKSPKFFLKLPSVAIPHKKPIITPKDAIRPEVEIGVITRKIKRGATLNEIKKNIIGYTVFNDITYPPGIKEDSYYAYRR
DPSDGKVKKLLIRGTHFRNKVRDSFAPFGPWIVTPEEIDDVNSLEMKSYYDGKLVQEGNSEDFVFSIEEIILELTKYVTL
PEFSLISSGSVGYIGAEEVSEFSLKPINNAIMVAEVEKIGKLENPTIIDENNV
>Mature_293_residues
MLFRLTKFLSFLVNNTRKLGILNGNYIYEVKDFYSTEPKGEAYKIDEIEFDIPVMPSAIICTLVNTPGMIGVKDKSEARE
FIKSPKFFLKLPSVAIPHKKPIITPKDAIRPEVEIGVITRKIKRGATLNEIKKNIIGYTVFNDITYPPGIKEDSYYAYRR
DPSDGKVKKLLIRGTHFRNKVRDSFAPFGPWIVTPEEIDDVNSLEMKSYYDGKLVQEGNSEDFVFSIEEIILELTKYVTL
PEFSLISSGSVGYIGAEEVSEFSLKPINNAIMVAEVEKIGKLENPTIIDENNV

Specific function: Decarboxylates OPET (5-oxo-pent-3-ene-1,2,5- tricarboxylic acid) into HHDD (2-hydroxy-hept-2,4-diene-1,7- dioate) and isomerizes it to OHED (2-oxo-hept-3-ene-1,7-dioate) [H]

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Drosophila melanogaster, GI28572127, Length=231, Percent_Identity=24.2424242424242, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234
- InterPro:   IPR012684
- InterPro:   IPR012686 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =5.3.3.10; =4.1.1.68 [H]

Molecular weight: Translated: 33205; Mature: 33205

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFRLTKFLSFLVNNTRKLGILNGNYIYEVKDFYSTEPKGEAYKIDEIEFDIPVMPSAII
CHHHHHHHHHHHHCCCEEEEEECCCEEEEEHHHHCCCCCCCEEEECCEEECCCCCCHHHE
CTLVNTPGMIGVKDKSEAREFIKSPKFFLKLPSVAIPHKKPIITPKDAIRPEVEIGVITR
EEEECCCCEEEECCHHHHHHHHHCCCEEEECCCEECCCCCCCCCCHHHCCCCEEEHHHHH
KIKRGATLNEIKKNIIGYTVFNDITYPPGIKEDSYYAYRRDPSDGKVKKLLIRGTHFRNK
HHHCCCCHHHHHHHHCCEEEECCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCHHHHHH
VRDSFAPFGPWIVTPEEIDDVNSLEMKSYYDGKLVQEGNSEDFVFSIEEIILELTKYVTL
HHHCCCCCCCEEECHHHHCCCCCEEHHHHCCCEEEECCCCCCEEEEHHHHHHHHHHHCCC
PEFSLISSGSVGYIGAEEVSEFSLKPINNAIMVAEVEKIGKLENPTIIDENNV
CCHHEECCCCCCEEEHHHHHHCCCCCCCCEEEEEEHHHHCCCCCCEEECCCCC
>Mature Secondary Structure
MLFRLTKFLSFLVNNTRKLGILNGNYIYEVKDFYSTEPKGEAYKIDEIEFDIPVMPSAII
CHHHHHHHHHHHHCCCEEEEEECCCEEEEEHHHHCCCCCCCEEEECCEEECCCCCCHHHE
CTLVNTPGMIGVKDKSEAREFIKSPKFFLKLPSVAIPHKKPIITPKDAIRPEVEIGVITR
EEEECCCCEEEECCHHHHHHHHHCCCEEEECCCEECCCCCCCCCCHHHCCCCEEEHHHHH
KIKRGATLNEIKKNIIGYTVFNDITYPPGIKEDSYYAYRRDPSDGKVKKLLIRGTHFRNK
HHHCCCCHHHHHHHHCCEEEECCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCHHHHHH
VRDSFAPFGPWIVTPEEIDDVNSLEMKSYYDGKLVQEGNSEDFVFSIEEIILELTKYVTL
HHHCCCCCCCEEECHHHHCCCCCEEHHHHCCCEEEECCCCCCEEEEHHHHHHHHHHHCCC
PEFSLISSGSVGYIGAEEVSEFSLKPINNAIMVAEVEKIGKLENPTIIDENNV
CCHHEECCCCCCEEEHHHHHHCCCCCCCCEEEEEEHHHHCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA