Click here to switch to the map view.

The map label for this gene is bphC [H]

Identifier: 15920954

GI number: 15920954

Start: 708802

End: 709752

Strand: Direct

Name: bphC [H]

Synonym: ST0724

Alternate gene names: 15920954

Gene position: 708802-709752 (Clockwise)

Preceding gene: 15920953

Following gene: 15920956

Centisome position: 26.3

GC content: 37.33

Gene sequence:

>951_bases
ATGATTGATATCCTACGTTTATCTCATGTGGGAATAAGAGTTACTGATCTAGAGAAAGCAAGATATTTTTACGTAGATTT
ACTAGGATTTGTGGAAACAGAAAAGGATGGTGACTACATATATTTAAGGGGTATCGATGAGGGACAGCACCACAGCTTAG
TTCTTAAAAAGGCTGACTCTCCCGGTTTGTCATATATTGGATTTAGAGTAAGAAGAGCTGAGGAGCTCGATAAGGCTAAA
GAAGAGCTACAAAAGCTTAACCTAAAATTTACCAGGTTTAAGGAGAAAGGTGTTGAGGAAGCCATACTCTTTGAGACTCC
TCAAGGTATGCCGTTTCTAATCTATTACGATATGGAGTATGTTGGAGATATGAGAATGAAGTTTTATGCACATAGAGGTG
TTTCACCAGTAAGGTTAGCTCATGTAAATTATGTGGTAAAGGATATTGAGGAAGAAGTTCAATTCCTTAAAAACTTTATG
GGCTATTATGAAACTGAATGGTTCTTAGGAAAAGATAATCAAACCAGAGAAGTAATTTGGCTTACAAGAAGGGGAGATTC
ACACGAGATTGCAATTGCTAAAAGTCAAAAAAATGTTCCAGGATTTCATCACGAGACTTACTACGTTCATGAGCTAAAAG
ATGTAATCAGAGCAGCTGATATTGTAGCTTCAGCAGAATTATGGGATAGTATTGAGAGGGGTCCGGGTAGACATGGAGTT
ACGGAGGGTTATTATGTTTATCTTAGAGATTTTGATAAAAATAGGATTGAGTTCTTTACAGAGGATTACGTAGTTTTAGA
CCCAGATAAATGGAAACCAGTAGTATGGAGAAATGAACAGTTTAGATATAGAAGTGATTTTTGGGGAAGACCAATTCCCC
AATCTTGGTTAAGTGAATGGGTTCCCGTGGAGGATATTTCCACGGGTAAATTAAAGGGGTGGTCTATTTGA

Upstream 100 bases:

>100_bases
TATATGAATAGAAAATACTATAAACTCTCTAGCTTGTAGGCTTATTCCTTTAATAAGTTTAATATACCATTTATTTAACC
TTTTTCGATAGACTTATTTG

Downstream 100 bases:

>100_bases
TTAGGAAAGGAGAAGACTATATAAAAAGTATAAAGGCCCATCATCCAGTAGTCTATTATGAAGGAGAAGTAGTAGAAGAT
ATAACTGAACATCAGGCGTT

Product: metapyrocatechase

Products: NA

Alternate protein names: Mn(II)-dependent 2,3-dihydroxybiphenyl 1,2-dioxygenase; Mn(II)-dependent 23OHBP oxygenase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MIDILRLSHVGIRVTDLEKARYFYVDLLGFVETEKDGDYIYLRGIDEGQHHSLVLKKADSPGLSYIGFRVRRAEELDKAK
EELQKLNLKFTRFKEKGVEEAILFETPQGMPFLIYYDMEYVGDMRMKFYAHRGVSPVRLAHVNYVVKDIEEEVQFLKNFM
GYYETEWFLGKDNQTREVIWLTRRGDSHEIAIAKSQKNVPGFHHETYYVHELKDVIRAADIVASAELWDSIERGPGRHGV
TEGYYVYLRDFDKNRIEFFTEDYVVLDPDKWKPVVWRNEQFRYRSDFWGRPIPQSWLSEWVPVEDISTGKLKGWSI

Sequences:

>Translated_316_residues
MIDILRLSHVGIRVTDLEKARYFYVDLLGFVETEKDGDYIYLRGIDEGQHHSLVLKKADSPGLSYIGFRVRRAEELDKAK
EELQKLNLKFTRFKEKGVEEAILFETPQGMPFLIYYDMEYVGDMRMKFYAHRGVSPVRLAHVNYVVKDIEEEVQFLKNFM
GYYETEWFLGKDNQTREVIWLTRRGDSHEIAIAKSQKNVPGFHHETYYVHELKDVIRAADIVASAELWDSIERGPGRHGV
TEGYYVYLRDFDKNRIEFFTEDYVVLDPDKWKPVVWRNEQFRYRSDFWGRPIPQSWLSEWVPVEDISTGKLKGWSI
>Mature_316_residues
MIDILRLSHVGIRVTDLEKARYFYVDLLGFVETEKDGDYIYLRGIDEGQHHSLVLKKADSPGLSYIGFRVRRAEELDKAK
EELQKLNLKFTRFKEKGVEEAILFETPQGMPFLIYYDMEYVGDMRMKFYAHRGVSPVRLAHVNYVVKDIEEEVQFLKNFM
GYYETEWFLGKDNQTREVIWLTRRGDSHEIAIAKSQKNVPGFHHETYYVHELKDVIRAADIVASAELWDSIERGPGRHGV
TEGYYVYLRDFDKNRIEFFTEDYVVLDPDKWKPVVWRNEQFRYRSDFWGRPIPQSWLSEWVPVEDISTGKLKGWSI

Specific function: Catalyzes the meta-cleavage of the hydroxylated biphenyl ring. The enzyme can oxidize a wide range of substrates, and the substrate preference order is 2,3-dihydroxybiphenyl > 3- methylcatechol > catechol > 4-methylcatechol > 4-chlorocatechol [H]

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the extradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: =1.13.11.39 [H]

Molecular weight: Translated: 37446; Mature: 37446

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00934 GLYOXALASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDILRLSHVGIRVTDLEKARYFYVDLLGFVETEKDGDYIYLRGIDEGQHHSLVLKKADS
CEEEEEECCCCEEEEECCCHHEEEEEEEHHEEECCCCCEEEEEECCCCCCCEEEEEECCC
PGLSYIGFRVRRAEELDKAKEELQKLNLKFTRFKEKGVEEAILFETPQGMPFLIYYDMEY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCEEEEEECCCCCEEEEEECHHH
VGDMRMKFYAHRGVSPVRLAHVNYVVKDIEEEVQFLKNFMGYYETEWFLGKDNQTREVIW
HCCHHEEEHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEE
LTRRGDSHEIAIAKSQKNVPGFHHETYYVHELKDVIRAADIVASAELWDSIERGPGRHGV
EEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TEGYYVYLRDFDKNRIEFFTEDYVVLDPDKWKPVVWRNEQFRYRSDFWGRPIPQSWLSEW
CCCEEEEEEECCCCCEEEEECCEEEECCCCCCCEEEECCCCEECCCCCCCCCCHHHHHCC
VPVEDISTGKLKGWSI
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIDILRLSHVGIRVTDLEKARYFYVDLLGFVETEKDGDYIYLRGIDEGQHHSLVLKKADS
CEEEEEECCCCEEEEECCCHHEEEEEEEHHEEECCCCCEEEEEECCCCCCCEEEEEECCC
PGLSYIGFRVRRAEELDKAKEELQKLNLKFTRFKEKGVEEAILFETPQGMPFLIYYDMEY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCEEEEEECCCCCEEEEEECHHH
VGDMRMKFYAHRGVSPVRLAHVNYVVKDIEEEVQFLKNFMGYYETEWFLGKDNQTREVIW
HCCHHEEEHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEE
LTRRGDSHEIAIAKSQKNVPGFHHETYYVHELKDVIRAADIVASAELWDSIERGPGRHGV
EEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TEGYYVYLRDFDKNRIEFFTEDYVVLDPDKWKPVVWRNEQFRYRSDFWGRPIPQSWLSEW
CCCEEEEEEECCCCCEEEEECCEEEECCCCCCCEEEECCCCEECCCCCCCCCCHHHHHCC
VPVEDISTGKLKGWSI
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12672826 [H]