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The map label for this gene is 15920822

Identifier: 15920822

GI number: 15920822

Start: 589014

End: 590183

Strand: Reverse

Name: 15920822

Synonym: ST0602

Alternate gene names: NA

Gene position: 590183-589014 (Counterclockwise)

Preceding gene: 15920824

Following gene: 15920821

Centisome position: 21.9

GC content: 35.3

Gene sequence:

>1170_bases
ATGATTCAAAAAGAAAAAAAGCTCTTAATGCATGTAGGCCCAGTAAATATTTTAGACAGAGTACTATATGCAGGTTTAAA
AAATAATGTGGGGTTTACGTCTCAAGAATTTGTGGAAGCTTTCCAATTCTCGTTAAAGAAAACAAGAGAATTGTTCCAGG
CTGACAATACATACCAACCATTTTTAATACCAGGTGGCGGGACATCAGCAATGGAAAGTGTAACATCATTACTTAAAGAA
GGTGAAAAAGTATTAGTAGTTACTAACGGAGTCTTTGGAGATAGATGGATAAATATATTCAGAAAATATCCAGTGAAAGT
TAATGTATTAAGCGCAGAACCAGGTTATTATGTTGAACCAGAGACAGTTGAAAAAGAAGTAAAAAAGGACAAATATACAT
TAGTTACTTTTACACATGTGGAGACAAGTACCGGAGTAAGGCAACCAATCAAGGATAGTGTGAAAGCCGTAAGGGATTAT
GTTGATTTGGTAGTTGTTGATGGAGTTTCAAGTGTTGGTGCAGAAGAAGTAAAGGCAAAGGATTGGAGAGTTGATGTTTA
TTTAACAGCTAGTCAAAAAGCCCTAGGTGTTCCTCCAGGGTTAGGAATTTTAGTACTTTCCGAAAGGGCTATGGAAAGGT
TAAAAGATGAAAAAAGTATTGCTGGTTATTACTTAGACTTAAGGAATTGGTTACCAGTTATGAATAGTATGGAAAATGGA
AAAGCCTCATATTTCTCTACACCTCCAGTGCATACAATATTAATGCTGTCTGAGGCATTAAAAATAATTATAGATGAAGA
GGGATTAGAAAGTAGAATTAAAAGACATGAAAAAGTGGCTAGTGCAATAAGAGCTGGAATAGAGGGAATGGGATTAGAAA
TCGTTGCTAAAAAACCAGAAGCATATAGTAACACTGTAACAGGAGTAGTTGTTAAGAAAGTTAATGCTGGTAACGTACTT
TCTGAAATAGTTTCAGAGGGTGTTGAATTAGCTCCAGGGGTTCATCCAAAATTGCAAGGAAAGTACTTTAGGATTGGCCA
TATGGGATGGGTGACTGAAAATGATGCCATAGTAACAATAGCTTCAATAGAAAGAGTGCTGAATAAATTAGGAGAAGAGA
TAAGATTAGGAGAAGGCATAAAAGCAACTCAGTTATATTTAGCAAAATAA

Upstream 100 bases:

>100_bases
GTAAATAATGGTATTTCTATGTTAAATTCTAGAATATCGAAAAATTTTGCTAAACTTATGAATAGAAAGAATAAATAATT
ATATTTCACCTTAATATCTC

Downstream 100 bases:

>100_bases
TTTTTATTCCTCCTTATGGATAACCTATCCATGGACATATATGAAGTTATAAAAAGAAGAAGAGATATCAGAAGTTATTG
CAAAAGTGACCCGATACCAG

Product: serine--pyruvate aminotransferase

Products: 3-hydroxypyruvate; L-alanine

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MIQKEKKLLMHVGPVNILDRVLYAGLKNNVGFTSQEFVEAFQFSLKKTRELFQADNTYQPFLIPGGGTSAMESVTSLLKE
GEKVLVVTNGVFGDRWINIFRKYPVKVNVLSAEPGYYVEPETVEKEVKKDKYTLVTFTHVETSTGVRQPIKDSVKAVRDY
VDLVVVDGVSSVGAEEVKAKDWRVDVYLTASQKALGVPPGLGILVLSERAMERLKDEKSIAGYYLDLRNWLPVMNSMENG
KASYFSTPPVHTILMLSEALKIIIDEEGLESRIKRHEKVASAIRAGIEGMGLEIVAKKPEAYSNTVTGVVVKKVNAGNVL
SEIVSEGVELAPGVHPKLQGKYFRIGHMGWVTENDAIVTIASIERVLNKLGEEIRLGEGIKATQLYLAK

Sequences:

>Translated_389_residues
MIQKEKKLLMHVGPVNILDRVLYAGLKNNVGFTSQEFVEAFQFSLKKTRELFQADNTYQPFLIPGGGTSAMESVTSLLKE
GEKVLVVTNGVFGDRWINIFRKYPVKVNVLSAEPGYYVEPETVEKEVKKDKYTLVTFTHVETSTGVRQPIKDSVKAVRDY
VDLVVVDGVSSVGAEEVKAKDWRVDVYLTASQKALGVPPGLGILVLSERAMERLKDEKSIAGYYLDLRNWLPVMNSMENG
KASYFSTPPVHTILMLSEALKIIIDEEGLESRIKRHEKVASAIRAGIEGMGLEIVAKKPEAYSNTVTGVVVKKVNAGNVL
SEIVSEGVELAPGVHPKLQGKYFRIGHMGWVTENDAIVTIASIERVLNKLGEEIRLGEGIKATQLYLAK
>Mature_389_residues
MIQKEKKLLMHVGPVNILDRVLYAGLKNNVGFTSQEFVEAFQFSLKKTRELFQADNTYQPFLIPGGGTSAMESVTSLLKE
GEKVLVVTNGVFGDRWINIFRKYPVKVNVLSAEPGYYVEPETVEKEVKKDKYTLVTFTHVETSTGVRQPIKDSVKAVRDY
VDLVVVDGVSSVGAEEVKAKDWRVDVYLTASQKALGVPPGLGILVLSERAMERLKDEKSIAGYYLDLRNWLPVMNSMENG
KASYFSTPPVHTILMLSEALKIIIDEEGLESRIKRHEKVASAIRAGIEGMGLEIVAKKPEAYSNTVTGVVVKKVNAGNVL
SEIVSEGVELAPGVHPKLQGKYFRIGHMGWVTENDAIVTIASIERVLNKLGEEIRLGEGIKATQLYLAK

Specific function: Unknown

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=350, Percent_Identity=29.7142857142857, Blast_Score=152, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17536281, Length=373, Percent_Identity=30.2949061662198, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6321079, Length=367, Percent_Identity=37.6021798365123, Blast_Score=199, Evalue=5e-52,
Organism=Drosophila melanogaster, GI17530823, Length=391, Percent_Identity=28.9002557544757, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.51

Molecular weight: Translated: 43041; Mature: 43041

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQKEKKLLMHVGPVNILDRVLYAGLKNNVGFTSQEFVEAFQFSLKKTRELFQADNTYQP
CCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
FLIPGGGTSAMESVTSLLKEGEKVLVVTNGVFGDRWINIFRKYPVKVNVLSAEPGYYVEP
EEEECCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCEEEEEEECCCCCEECC
ETVEKEVKKDKYTLVTFTHVETSTGVRQPIKDSVKAVRDYVDLVVVDGVSSVGAEEVKAK
HHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCHHHHCCC
DWRVDVYLTASQKALGVPPGLGILVLSERAMERLKDEKSIAGYYLDLRNWLPVMNSMENG
CEEEEEEEEECCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KASYFSTPPVHTILMLSEALKIIIDEEGLESRIKRHEKVASAIRAGIEGMGLEIVAKKPE
CCCCCCCCCHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
AYSNTVTGVVVKKVNAGNVLSEIVSEGVELAPGVHPKLQGKYFRIGHMGWVTENDAIVTI
HHCCCEEEEEEEECCCCHHHHHHHHCCHHCCCCCCCCCCCCEEEEEEEEEEECCCCEEEH
ASIERVLNKLGEEIRLGEGIKATQLYLAK
HHHHHHHHHHHHHHCCCCCCCCCEEEECC
>Mature Secondary Structure
MIQKEKKLLMHVGPVNILDRVLYAGLKNNVGFTSQEFVEAFQFSLKKTRELFQADNTYQP
CCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
FLIPGGGTSAMESVTSLLKEGEKVLVVTNGVFGDRWINIFRKYPVKVNVLSAEPGYYVEP
EEEECCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCEEEEEEECCCCCEECC
ETVEKEVKKDKYTLVTFTHVETSTGVRQPIKDSVKAVRDYVDLVVVDGVSSVGAEEVKAK
HHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCHHHHCCC
DWRVDVYLTASQKALGVPPGLGILVLSERAMERLKDEKSIAGYYLDLRNWLPVMNSMENG
CEEEEEEEEECCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KASYFSTPPVHTILMLSEALKIIIDEEGLESRIKRHEKVASAIRAGIEGMGLEIVAKKPE
CCCCCCCCCHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
AYSNTVTGVVVKKVNAGNVLSEIVSEGVELAPGVHPKLQGKYFRIGHMGWVTENDAIVTI
HHCCCEEEEEEEECCCCHHHHHHHHCCHHCCCCCCCCCCCCEEEEEEEEEEECCCCEEEH
ASIERVLNKLGEEIRLGEGIKATQLYLAK
HHHHHHHHHHHHHHCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-serine; pyruvate

Specific reaction: L-serine + pyruvate = 3-hydroxypyruvate + L-alanine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]