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The map label for this gene is adh [H]

Identifier: 15920787

GI number: 15920787

Start: 559971

End: 560972

Strand: Direct

Name: adh [H]

Synonym: ST0569

Alternate gene names: 15920787

Gene position: 559971-560972 (Clockwise)

Preceding gene: 15920786

Following gene: 15920789

Centisome position: 20.78

GC content: 35.13

Gene sequence:

>1002_bases
ATGAAAGCTGCTGTCTTCAGAGAAATAGGTAAACCATTAAGCATAGAAGATGTTCAGTTGCCCCGTTTAGAGTCTGATAA
GGAAGTATTATTAAAGGTTAAAGCTACTGGTGTTTGTCATGGGGACTTACATGTAATAATGGGAGACTGGCAATACGAAG
TACCCGTTAATACCCCAATTATTTTAGGTCATGAAATAATAGGTGAAGTAGTTGAAGGAGGAACAAAATTCCAAAAAGGA
GATTTAGTTATGGTATACAATGCTTTTGGTTGTAAAGAATGTAAACATTGCAAGGCGGGGTATTATCAATTCTGTGAAAG
AGTAAAAGTGTTGGGAGTTCATTTAAATGGGGGATTCGCAGAATATGTGAAAGTACCCGATGAAGATTTCCTTATGAGAG
TTGAAGGTAACCCAATTCAATTAGCCCCTTTGGCAGATGCTGGAGTAACAGCATATAGTGCAACTAGAGGTATAAAAGAA
GGTGATAAGGTTTTAGTTGTTGGGACTGGAGCTGTTGCACTTTTGGCAATACAAATTTTAAAAAGTCTTAAAGCCGAAGT
AAGTGTAGTTAGTCGTAATCCAACAAGGTTGGCTAAAGCTGAAGAACTTGGGGCTGATCATGTATATTATAGGAAAAAAA
CTTTTCCATCATTATATACTTCTATAGTAGGAAAAAAATTTGATTATATTATAGATTTTGTAGGATCTGACGAAACTCTT
GATGAAGTAGCATGGCTTTTAGATAGAAGAGGTGAACTTAGAATAGTAGGCGAATTTGGAGGACAATTATCCATTCCAGA
ACAATTATTAGTGTTAAGAGGACTTAAAGTACAAGGAATTCTTTATGGTACTATGGACGATATGAAAGGGGTAATTAATC
TTTATAATTCTGGTAAGTTAAAAACTCTTGCCGTACCTTATTATCTAGATGAAATAAATGATGCCTTAAATGATTTAATG
CAAGAGAGAATTTTGGGAAGGGCTGTCATAATTCCTTCTTAG

Upstream 100 bases:

>100_bases
GTAGATACCTTCATTGAATTGAAGAAGAAAGAAATTGAAGATTACGAAAAAGAAATAACAGAGTGGGAAATTAATTCTTA
TCTCAAGTCTGGATGGTAAC

Downstream 100 bases:

>100_bases
CTCTAAAAATGAATGGTTTTTCGCCAGAAATTTGAATATTCACATTAAGAAACTTTTTGATAATCTCTGAATTAGTTCTT
GCATGAGATGTGAGTTCAGA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKAAVFREIGKPLSIEDVQLPRLESDKEVLLKVKATGVCHGDLHVIMGDWQYEVPVNTPIILGHEIIGEVVEGGTKFQKG
DLVMVYNAFGCKECKHCKAGYYQFCERVKVLGVHLNGGFAEYVKVPDEDFLMRVEGNPIQLAPLADAGVTAYSATRGIKE
GDKVLVVGTGAVALLAIQILKSLKAEVSVVSRNPTRLAKAEELGADHVYYRKKTFPSLYTSIVGKKFDYIIDFVGSDETL
DEVAWLLDRRGELRIVGEFGGQLSIPEQLLVLRGLKVQGILYGTMDDMKGVINLYNSGKLKTLAVPYYLDEINDALNDLM
QERILGRAVIIPS

Sequences:

>Translated_333_residues
MKAAVFREIGKPLSIEDVQLPRLESDKEVLLKVKATGVCHGDLHVIMGDWQYEVPVNTPIILGHEIIGEVVEGGTKFQKG
DLVMVYNAFGCKECKHCKAGYYQFCERVKVLGVHLNGGFAEYVKVPDEDFLMRVEGNPIQLAPLADAGVTAYSATRGIKE
GDKVLVVGTGAVALLAIQILKSLKAEVSVVSRNPTRLAKAEELGADHVYYRKKTFPSLYTSIVGKKFDYIIDFVGSDETL
DEVAWLLDRRGELRIVGEFGGQLSIPEQLLVLRGLKVQGILYGTMDDMKGVINLYNSGKLKTLAVPYYLDEINDALNDLM
QERILGRAVIIPS
>Mature_333_residues
MKAAVFREIGKPLSIEDVQLPRLESDKEVLLKVKATGVCHGDLHVIMGDWQYEVPVNTPIILGHEIIGEVVEGGTKFQKG
DLVMVYNAFGCKECKHCKAGYYQFCERVKVLGVHLNGGFAEYVKVPDEDFLMRVEGNPIQLAPLADAGVTAYSATRGIKE
GDKVLVVGTGAVALLAIQILKSLKAEVSVVSRNPTRLAKAEELGADHVYYRKKTFPSLYTSIVGKKFDYIIDFVGSDETL
DEVAWLLDRRGELRIVGEFGGQLSIPEQLLVLRGLKVQGILYGTMDDMKGVINLYNSGKLKTLAVPYYLDEINDALNDLM
QERILGRAVIIPS

Specific function: Unknown

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI34577061, Length=329, Percent_Identity=28.2674772036474, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI71743840, Length=345, Percent_Identity=27.8260869565217, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI262073058, Length=345, Percent_Identity=26.9565217391304, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4501933, Length=331, Percent_Identity=27.7945619335347, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI71565154, Length=233, Percent_Identity=31.7596566523605, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI156627571, Length=291, Percent_Identity=26.4604810996564, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4501929, Length=275, Percent_Identity=28.3636363636364, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI156523966, Length=371, Percent_Identity=25.6064690026954, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI4501939, Length=361, Percent_Identity=26.0387811634349, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI226510992, Length=310, Percent_Identity=29.6774193548387, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786518, Length=337, Percent_Identity=26.7062314540059, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788073, Length=281, Percent_Identity=29.8932384341637, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790045, Length=290, Percent_Identity=25.8620689655172, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082401, Length=339, Percent_Identity=26.2536873156342, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787863, Length=258, Percent_Identity=31.7829457364341, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1786825, Length=265, Percent_Identity=30.9433962264151, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081918, Length=341, Percent_Identity=30.2052785923754, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082125, Length=226, Percent_Identity=30.9734513274336, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788407, Length=248, Percent_Identity=26.6129032258064, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790718, Length=305, Percent_Identity=23.6065573770492, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786552, Length=376, Percent_Identity=29.7872340425532, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71988145, Length=338, Percent_Identity=25.4437869822485, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17562584, Length=342, Percent_Identity=24.5614035087719, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17562876, Length=332, Percent_Identity=25.9036144578313, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17562582, Length=342, Percent_Identity=24.8538011695906, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562878, Length=191, Percent_Identity=32.4607329842932, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25146526, Length=375, Percent_Identity=27.2, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71997431, Length=376, Percent_Identity=26.8617021276596, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319949, Length=204, Percent_Identity=35.7843137254902, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323980, Length=293, Percent_Identity=31.3993174061433, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6323729, Length=341, Percent_Identity=24.3401759530792, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323961, Length=340, Percent_Identity=24.4117647058824, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319621, Length=340, Percent_Identity=24.1176470588235, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=343, Percent_Identity=23.3236151603499, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319258, Length=296, Percent_Identity=26.6891891891892, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319955, Length=319, Percent_Identity=24.7648902821317, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322619, Length=319, Percent_Identity=24.7648902821317, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320033, Length=371, Percent_Identity=26.6846361185984, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323099, Length=313, Percent_Identity=23.961661341853, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17737895, Length=373, Percent_Identity=28.9544235924933, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17137530, Length=304, Percent_Identity=25, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI17737897, Length=315, Percent_Identity=26.3492063492064, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36732; Mature: 36732

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAVFREIGKPLSIEDVQLPRLESDKEVLLKVKATGVCHGDLHVIMGDWQYEVPVNTPI
CCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECEEEECCEEEEEECEEEECCCCCCE
ILGHEIIGEVVEGGTKFQKGDLVMVYNAFGCKECKHCKAGYYQFCERVKVLGVHLNGGFA
EECHHHHHHHHCCCCCEECCCEEEEEECCCCCHHHHHCCHHHHHHHHEEEEEEEECCCCE
EYVKVPDEDFLMRVEGNPIQLAPLADAGVTAYSATRGIKEGDKVLVVGTGAVALLAIQIL
EEEECCCHHEEEEECCCEEEEEECCCCCCCHHHHHCCCCCCCEEEEEECCHHHHHHHHHH
KSLKAEVSVVSRNPTRLAKAEELGADHVYYRKKTFPSLYTSIVGKKFDYIIDFVGSDETL
HHHHHHEEEECCCCHHHHHHHHCCCCCEEEEHHCCHHHHHHHHCCCCEEEEEECCCCCHH
DEVAWLLDRRGELRIVGEFGGQLSIPEQLLVLRGLKVQGILYGTMDDMKGVINLYNSGKL
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCCEEEEEEEECHHHHHHHHHHHCCCCE
KTLAVPYYLDEINDALNDLMQERILGRAVIIPS
EEEECHHHHHHHHHHHHHHHHHHHHCCEEEECC
>Mature Secondary Structure
MKAAVFREIGKPLSIEDVQLPRLESDKEVLLKVKATGVCHGDLHVIMGDWQYEVPVNTPI
CCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECEEEECCEEEEEECEEEECCCCCCE
ILGHEIIGEVVEGGTKFQKGDLVMVYNAFGCKECKHCKAGYYQFCERVKVLGVHLNGGFA
EECHHHHHHHHCCCCCEECCCEEEEEECCCCCHHHHHCCHHHHHHHHEEEEEEEECCCCE
EYVKVPDEDFLMRVEGNPIQLAPLADAGVTAYSATRGIKEGDKVLVVGTGAVALLAIQIL
EEEECCCHHEEEEECCCEEEEEECCCCCCCHHHHHCCCCCCCEEEEEECCHHHHHHHHHH
KSLKAEVSVVSRNPTRLAKAEELGADHVYYRKKTFPSLYTSIVGKKFDYIIDFVGSDETL
HHHHHHEEEECCCCHHHHHHHHCCCCCEEEEHHCCHHHHHHHHCCCCEEEEEECCCCCHH
DEVAWLLDRRGELRIVGEFGGQLSIPEQLLVLRGLKVQGILYGTMDDMKGVINLYNSGKL
HHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCCEEEEEEEECHHHHHHHHHHHCCCCE
KTLAVPYYLDEINDALNDLMQERILGRAVIIPS
EEEECHHHHHHHHHHHHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]