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The map label for this gene is ksgA [H]

Identifier: 15920668

GI number: 15920668

Start: 459617

End: 460279

Strand: Reverse

Name: ksgA [H]

Synonym: ST0456

Alternate gene names: 15920668

Gene position: 460279-459617 (Counterclockwise)

Preceding gene: 15920669

Following gene: 15920667

Centisome position: 17.08

GC content: 25.04

Gene sequence:

>663_bases
ATGAATCTGGGTCAACATTTTCTAGTTAATGAGGAAACTATAAAAAGATTTGTTTCTTATGTTGATCTCTCTTTTAGGCC
AATAATAGAAATTGGTGGTGGAAAAGGTAATATTACTAAATATATCAAACCAGATGTAGTAATTGAAATTGATAAGAGAT
TTTCTTCTTATCTTCGTAATCTTGTTATAGCTGACGCTAGATTCCTACCCGTAATAAGAGGCCAAATAGTTTCATCGTTG
CCATATTACATTACTTATGAATTCTTTGAAGAAATAATTAGAATAGATCAAATTAAGAAACTAATTCTTATTTTACAATA
TGATTTTGTTAAAAAAATATTAAATGAGCCTACTTATATCTCTTTCATACTAAATTATTATTATAAAATAGATGTGAAAG
AAAATATTCCGCCATGGTTTTTTAAACCAAAACCAAGGGTTTATTCTACTATTGTTCTTTTTACAAGAATTAGAAGTTAT
GATGAGAAAATAAATTTGATTTTGAAATGCATAAGTAAATATAGAAATAAAAAAATTACAAATGCTGTAAAACTATGTAA
TTTATCTTCTTCTTTAAGTACGGATATAAATAAAAGAGTAAGGGATTTTAAACCATGTCAAGTTTTAGAGTTATTGAATA
TAATAAGTACAAAATATGTCTAA

Upstream 100 bases:

>100_bases
AAATATTATCTATTTGTATATCCGTTATTTGATGAAAAGAGTAAAAAACTTGGTGAACATTCTATCTATATAGGGTACCT
AGAGAAATTGGGAAAATATA

Downstream 100 bases:

>100_bases
ATGATGAAACTTATGAACCATCAGATGACACTGGATTATTATTAGATATAATAAAGATAAATAAAGGAGAGAAAGTAATT
GATATTGGGACTGGAACTGG

Product: dimethyladenosine transferase

Products: NA

Alternate protein names: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase; 16S rRNA dimethyladenosine transferase; 16S rRNA dimethylase; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MNLGQHFLVNEETIKRFVSYVDLSFRPIIEIGGGKGNITKYIKPDVVIEIDKRFSSYLRNLVIADARFLPVIRGQIVSSL
PYYITYEFFEEIIRIDQIKKLILILQYDFVKKILNEPTYISFILNYYYKIDVKENIPPWFFKPKPRVYSTIVLFTRIRSY
DEKINLILKCISKYRNKKITNAVKLCNLSSSLSTDINKRVRDFKPCQVLELLNIISTKYV

Sequences:

>Translated_220_residues
MNLGQHFLVNEETIKRFVSYVDLSFRPIIEIGGGKGNITKYIKPDVVIEIDKRFSSYLRNLVIADARFLPVIRGQIVSSL
PYYITYEFFEEIIRIDQIKKLILILQYDFVKKILNEPTYISFILNYYYKIDVKENIPPWFFKPKPRVYSTIVLFTRIRSY
DEKINLILKCISKYRNKKITNAVKLCNLSSSLSTDINKRVRDFKPCQVLELLNIISTKYV
>Mature_220_residues
MNLGQHFLVNEETIKRFVSYVDLSFRPIIEIGGGKGNITKYIKPDVVIEIDKRFSSYLRNLVIADARFLPVIRGQIVSSL
PYYITYEFFEEIIRIDQIKKLILILQYDFVKKILNEPTYISFILNYYYKIDVKENIPPWFFKPKPRVYSTIVLFTRIRSY
DEKINLILKCISKYRNKKITNAVKLCNLSSSLSTDINKRVRDFKPCQVLELLNIISTKYV

Specific function: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits [H]

COG id: COG0030

COG function: function code J; Dimethyladenosine transferase (rRNA methylation)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023165
- InterPro:   IPR020596
- InterPro:   IPR001737
- InterPro:   IPR020598
- InterPro:   IPR011530 [H]

Pfam domain/function: PF00398 RrnaAD [H]

EC number: =2.1.1.182 [H]

Molecular weight: Translated: 26015; Mature: 26015

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLGQHFLVNEETIKRFVSYVDLSFRPIIEIGGGKGNITKYIKPDVVIEIDKRFSSYLRN
CCCCCHHEECHHHHHHHHHHHCCCCCEEEEECCCCCCCCEECCCCEEEEEHHHHHHHHHH
LVIADARFLPVIRGQIVSSLPYYITYEFFEEIIRIDQIKKLILILQYDFVKKILNEPTYI
HHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SFILNYYYKIDVKENIPPWFFKPKPRVYSTIVLFTRIRSYDEKINLILKCISKYRNKKIT
HHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
NAVKLCNLSSSLSTDINKRVRDFKPCQVLELLNIISTKYV
HHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLGQHFLVNEETIKRFVSYVDLSFRPIIEIGGGKGNITKYIKPDVVIEIDKRFSSYLRN
CCCCCHHEECHHHHHHHHHHHCCCCCEEEEECCCCCCCCEECCCCEEEEEHHHHHHHHHH
LVIADARFLPVIRGQIVSSLPYYITYEFFEEIIRIDQIKKLILILQYDFVKKILNEPTYI
HHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SFILNYYYKIDVKENIPPWFFKPKPRVYSTIVLFTRIRSYDEKINLILKCISKYRNKKIT
HHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
NAVKLCNLSSSLSTDINKRVRDFKPCQVLELLNIISTKYV
HHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7569993; 8253680 [H]