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The map label for this gene is gcp

Identifier: 15920565

GI number: 15920565

Start: 380325

End: 381335

Strand: Direct

Name: gcp

Synonym: ST0363

Alternate gene names: 15920565

Gene position: 380325-381335 (Clockwise)

Preceding gene: 15920564

Following gene: 15920566

Centisome position: 14.11

GC content: 34.32

Gene sequence:

>1011_bases
ATGAATGTTTTAGGGATCGAATCTACTGCTCATACTTTTGGAGTAGGTATAGTTTCTGATGATGATAGTGAAATAAGAAT
ATTATCAAATGAAAGGGATACTTTTGTCCCTAAACAAGGTGGAATGAAACCTAGTGATTTGGGTAGACATCATTCTGAAG
TTGCACCAGAAGTATTACAAAAGGCCTTAATAAAGGCTAATTTGAGCATAAGAGATATTAATTATATAGCAGTTTCTTTA
GGCCCTGGTATAGGGCCAGCATTAAGAGTAGGAGCTACAATAGCTAGAGCATTATCTTTAAAATATGACATTAAACTTGT
ACCCGTAAATCATGGAATTGCCCATATTGAAATAGGAAGATTTACAACTAGATCTAAAGATCCTTTAATCTTGTATCTTT
CTGGAGGGAATACTATAATAACAACTTATTTAGATGGCAAGTATAGAATTTTTGGTGAAACGTTAGATATAGCATTAGGA
AATATGTTAGACACATTTGTTAGAGAAGTAGGGCTAGCTCCTCCTTATATTGTAAACGGTGTTCATCAAATAGATTTATG
TGCAAATAAAGGTGGGAATTTTATTGAGCTACCATATATAGTAAAGGGTCAGGATATGTCTTATAGTGGTTTGCTAACTG
CTGCTTTAAGAGCGACAAAAAATAATAGACTTGAAGACGTATGTTATAGTGTTAGGGAAGTGGCTTTTGATATGTTATTA
GAGGCTACTGAAAGAGCATTAGCATTGACTGGAAAGAAAGAAATTCTTGTTGTTGGGGGTGTTGCAGCTAGTGTAAGTTT
AAAGACTAAGTTATATAATCTTGCGAAAGATTGGAATGTTGAAGTAAAAATAGTTCCACCAGAATATTCTGGAGATAACG
GGGCAATGATAGCTTTTACTGGTTTACTTGAGGCAAGGCACGGAGTTACAATTCCAGTAGAAAAAAGTATTATTAGACCT
AGATGGAGAGTAGATCAAGTAGATGTGACATGGAGATTATCAGAGAATTAA

Upstream 100 bases:

>100_bases
AATGTCCTAGATGCGGTAGTATTATGGCTCATCATATGAAACCTGTTGAGCGTTGGGCTTGTGGGAAGTGTGGTTACACT
GAGTTTATAGGTAAAGGGAA

Downstream 100 bases:

>100_bases
AGAGAGGAGCAGAGTCCATAATTTATGAAGGATATTTTGCGGGTATTCACGCTGTATTTAAGAAAAGAATATCTAAATCT
TATAGAGATCAAAAACTTGA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MNVLGIESTAHTFGVGIVSDDDSEIRILSNERDTFVPKQGGMKPSDLGRHHSEVAPEVLQKALIKANLSIRDINYIAVSL
GPGIGPALRVGATIARALSLKYDIKLVPVNHGIAHIEIGRFTTRSKDPLILYLSGGNTIITTYLDGKYRIFGETLDIALG
NMLDTFVREVGLAPPYIVNGVHQIDLCANKGGNFIELPYIVKGQDMSYSGLLTAALRATKNNRLEDVCYSVREVAFDMLL
EATERALALTGKKEILVVGGVAASVSLKTKLYNLAKDWNVEVKIVPPEYSGDNGAMIAFTGLLEARHGVTIPVEKSIIRP
RWRVDQVDVTWRLSEN

Sequences:

>Translated_336_residues
MNVLGIESTAHTFGVGIVSDDDSEIRILSNERDTFVPKQGGMKPSDLGRHHSEVAPEVLQKALIKANLSIRDINYIAVSL
GPGIGPALRVGATIARALSLKYDIKLVPVNHGIAHIEIGRFTTRSKDPLILYLSGGNTIITTYLDGKYRIFGETLDIALG
NMLDTFVREVGLAPPYIVNGVHQIDLCANKGGNFIELPYIVKGQDMSYSGLLTAALRATKNNRLEDVCYSVREVAFDMLL
EATERALALTGKKEILVVGGVAASVSLKTKLYNLAKDWNVEVKIVPPEYSGDNGAMIAFTGLLEARHGVTIPVEKSIIRP
RWRVDQVDVTWRLSEN
>Mature_336_residues
MNVLGIESTAHTFGVGIVSDDDSEIRILSNERDTFVPKQGGMKPSDLGRHHSEVAPEVLQKALIKANLSIRDINYIAVSL
GPGIGPALRVGATIARALSLKYDIKLVPVNHGIAHIEIGRFTTRSKDPLILYLSGGNTIITTYLDGKYRIFGETLDIALG
NMLDTFVREVGLAPPYIVNGVHQIDLCANKGGNFIELPYIVKGQDMSYSGLLTAALRATKNNRLEDVCYSVREVAFDMLL
EATERALALTGKKEILVVGGVAASVSLKTKLYNLAKDWNVEVKIVPPEYSGDNGAMIAFTGLLEARHGVTIPVEKSIIRP
RWRVDQVDVTWRLSEN

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI8923380, Length=341, Percent_Identity=40.7624633431085, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI116812636, Length=339, Percent_Identity=25.0737463126844, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1789445, Length=338, Percent_Identity=32.5443786982249, Blast_Score=148, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI71995670, Length=339, Percent_Identity=39.8230088495575, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17557464, Length=333, Percent_Identity=27.9279279279279, Blast_Score=95, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6322891, Length=370, Percent_Identity=38.1081081081081, Blast_Score=236, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6320099, Length=339, Percent_Identity=25.0737463126844, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21357207, Length=351, Percent_Identity=38.4615384615385, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI20129063, Length=369, Percent_Identity=25.4742547425474, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_SULTO (Q975Q7)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376234.1
- ProteinModelPortal:   Q975Q7
- SMR:   Q975Q7
- MEROPS:   M22.003
- GeneID:   1458287
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST0363
- NMPDR:   fig|273063.1.peg.402
- HOGENOM:   HBG304663
- OMA:   TQRFRTD
- ProtClustDB:   PRK14878
- BioCyc:   STOK273063:ST0363-MONOMER
- BRENDA:   3.4.24.57
- GO:   GO:0006508
- HAMAP:   MF_01446
- InterPro:   IPR022449
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03722
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36708; Mature: 36708

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLGIESTAHTFGVGIVSDDDSEIRILSNERDTFVPKQGGMKPSDLGRHHSEVAPEVLQ
CCEEECCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHH
KALIKANLSIRDINYIAVSLGPGIGPALRVGATIARALSLKYDIKLVPVNHGIAHIEIGR
HHHHHCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHEEEEEEEEEEECCCEEEEEECC
FTTRSKDPLILYLSGGNTIITTYLDGKYRIFGETLDIALGNMLDTFVREVGLAPPYIVNG
EECCCCCCEEEEEECCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHCC
VHQIDLCANKGGNFIELPYIVKGQDMSYSGLLTAALRATKNNRLEDVCYSVREVAFDMLL
CEEEEEEECCCCCEEECCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EATERALALTGKKEILVVGGVAASVSLKTKLYNLAKDWNVEVKIVPPEYSGDNGAMIAFT
HHHHHHEEECCCCEEEEEECEEEEEEHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEE
GLLEARHGVTIPVEKSIIRPRWRVDQVDVTWRLSEN
EEHHHCCCEEEECHHHHCCCCCEEEEEEEEEEECCC
>Mature Secondary Structure
MNVLGIESTAHTFGVGIVSDDDSEIRILSNERDTFVPKQGGMKPSDLGRHHSEVAPEVLQ
CCEEECCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHH
KALIKANLSIRDINYIAVSLGPGIGPALRVGATIARALSLKYDIKLVPVNHGIAHIEIGR
HHHHHCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHEEEEEEEEEEECCCEEEEEECC
FTTRSKDPLILYLSGGNTIITTYLDGKYRIFGETLDIALGNMLDTFVREVGLAPPYIVNG
EECCCCCCEEEEEECCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHCC
VHQIDLCANKGGNFIELPYIVKGQDMSYSGLLTAALRATKNNRLEDVCYSVREVAFDMLL
CEEEEEEECCCCCEEECCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EATERALALTGKKEILVVGGVAASVSLKTKLYNLAKDWNVEVKIVPPEYSGDNGAMIAFT
HHHHHHEEECCCCEEEEEECEEEEEEHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEE
GLLEARHGVTIPVEKSIIRPRWRVDQVDVTWRLSEN
EEHHHCCCEEEECHHHHCCCCCEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479