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The map label for this gene is yciA [C]

Identifier: 15920495

GI number: 15920495

Start: 320809

End: 321732

Strand: Direct

Name: yciA [C]

Synonym: ST0303

Alternate gene names: 15920495

Gene position: 320809-321732 (Clockwise)

Preceding gene: 15920494

Following gene: 15920499

Centisome position: 11.9

GC content: 32.9

Gene sequence:

>924_bases
ATGATGAAATTAGAAACATATTATAATGTATATCCTTGGCATGCTAATCATTTTGGTAGTTTACATGGCGGAATTTATAT
GAACTGGTTAATAGATACAGCGGGCATGTTAATGTCTGGTATAAGTAGAGGCAACTATTTGCTTGCATCAGTAGATTATA
TTTATCTTTTTAAACCTGGTAAAGTCGGTGACGTAATTAGAATTATAGCAGAACCTTTAGCTAGTTGGGAAAGCTCTGTA
GAAATAAAAGTAAAGGCTTGTATAAAGAGGGATAATAAAGAAGAATTAGGAGCTTTAGGCTTAACTACATATGTAGCTGT
AGATGAGAATAATAGACCTAGACCACTACCCATAAAAATTGGAACTAACGAAGAAGCAAATAAAAGGAAAGAAAAAAGAT
TAGAAAGAAAGAAAAAAGATGCTGAAGATAATGAAGACCTTTTACCCGGAATGAGCTTTGGAAGAAGTTATATAAGAACT
ATATATCCAGAACATGGTTTTATGAATGGAATATTGTACGCTGGAAAGATGTATACAATGTTAGATGAGGCATTAGCTAT
AGTAGCTAAATTATACTCTAAAGGTAATGTGTTTACTGCAAGTGCAGGCTATGCTAATTTTCTCACTCCGGTTAGAATTG
GAGACATATTAGAAATTCAGGGGGCAATAGAATATACGGGTAATACTTCTTTGGATGTTGGAGCAAAAGTATTTGCTATT
AATCATTACACTGGTGAAAAAAGACTAGTCACCAGAACAGTATTCTCTTTTGTCGCAATAGATGAAAATGGCAAACCAAA
GCCAATAAACAAGATAACGCCAGCTACAGAAAAAGAAAAGAGAATATTTGATGAAAGATTAAAGGAAAGAGAAGAAAGAA
TAAAACTATCTAAAAACATTCAAGAAAGTGAGAGTTGTAGCTAA

Upstream 100 bases:

>100_bases
ATAAGGGGAGATGAAAGACTTAAAGCAATAGCTGGAATTTATTAAGCCACCAAATGGAAAATATTATATTTTTTAAACTA
TTATATATAACTGATAACTA

Downstream 100 bases:

>100_bases
ATGATTTTTTTAGATAAAAGAAATGTAGACAAACTACTTGAAATTTCATGAGCTATTTTTAGTGGTAAAGGTATTCTATC
AAATACTTGATATTCCTCAA

Product: cytosolic acyl-CoA thioester hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MMKLETYYNVYPWHANHFGSLHGGIYMNWLIDTAGMLMSGISRGNYLLASVDYIYLFKPGKVGDVIRIIAEPLASWESSV
EIKVKACIKRDNKEELGALGLTTYVAVDENNRPRPLPIKIGTNEEANKRKEKRLERKKKDAEDNEDLLPGMSFGRSYIRT
IYPEHGFMNGILYAGKMYTMLDEALAIVAKLYSKGNVFTASAGYANFLTPVRIGDILEIQGAIEYTGNTSLDVGAKVFAI
NHYTGEKRLVTRTVFSFVAIDENGKPKPINKITPATEKEKRIFDERLKEREERIKLSKNIQESESCS

Sequences:

>Translated_307_residues
MMKLETYYNVYPWHANHFGSLHGGIYMNWLIDTAGMLMSGISRGNYLLASVDYIYLFKPGKVGDVIRIIAEPLASWESSV
EIKVKACIKRDNKEELGALGLTTYVAVDENNRPRPLPIKIGTNEEANKRKEKRLERKKKDAEDNEDLLPGMSFGRSYIRT
IYPEHGFMNGILYAGKMYTMLDEALAIVAKLYSKGNVFTASAGYANFLTPVRIGDILEIQGAIEYTGNTSLDVGAKVFAI
NHYTGEKRLVTRTVFSFVAIDENGKPKPINKITPATEKEKRIFDERLKEREERIKLSKNIQESESCS
>Mature_307_residues
MMKLETYYNVYPWHANHFGSLHGGIYMNWLIDTAGMLMSGISRGNYLLASVDYIYLFKPGKVGDVIRIIAEPLASWESSV
EIKVKACIKRDNKEELGALGLTTYVAVDENNRPRPLPIKIGTNEEANKRKEKRLERKKKDAEDNEDLLPGMSFGRSYIRT
IYPEHGFMNGILYAGKMYTMLDEALAIVAKLYSKGNVFTASAGYANFLTPVRIGDILEIQGAIEYTGNTSLDVGAKVFAI
NHYTGEKRLVTRTVFSFVAIDENGKPKPINKITPATEKEKRIFDERLKEREERIKLSKNIQESESCS

Specific function: Unknown

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI32528284, Length=303, Percent_Identity=26.4026402640264, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI32528286, Length=303, Percent_Identity=26.4026402640264, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI32528282, Length=303, Percent_Identity=26.4026402640264, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI75709208, Length=303, Percent_Identity=26.4026402640264, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI18640736, Length=315, Percent_Identity=22.2222222222222, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 34694; Mature: 34694

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKLETYYNVYPWHANHFGSLHGGIYMNWLIDTAGMLMSGISRGNYLLASVDYIYLFKPG
CCEEECCCEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCC
KVGDVIRIIAEPLASWESSVEIKVKACIKRDNKEELGALGLTTYVAVDENNRPRPLPIKI
CHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHCCEEEEEEECCCCCCCCEEEEE
GTNEEANKRKEKRLERKKKDAEDNEDLLPGMSFGRSYIRTIYPEHGFMNGILYAGKMYTM
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LDEALAIVAKLYSKGNVFTASAGYANFLTPVRIGDILEIQGAIEYTGNTSLDVGAKVFAI
HHHHHHHHHHHHHCCCEEEECCCCHHCCCHHCCCCEEEECEEEEECCCCCCCCCEEEEEE
NHYTGEKRLVTRTVFSFVAIDENGKPKPINKITPATEKEKRIFDERLKEREERIKLSKNI
EECCCCHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
QESESCS
CCCCCCC
>Mature Secondary Structure
MMKLETYYNVYPWHANHFGSLHGGIYMNWLIDTAGMLMSGISRGNYLLASVDYIYLFKPG
CCEEECCCEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCC
KVGDVIRIIAEPLASWESSVEIKVKACIKRDNKEELGALGLTTYVAVDENNRPRPLPIKI
CHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHCCEEEEEEECCCCCCCCEEEEE
GTNEEANKRKEKRLERKKKDAEDNEDLLPGMSFGRSYIRTIYPEHGFMNGILYAGKMYTM
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LDEALAIVAKLYSKGNVFTASAGYANFLTPVRIGDILEIQGAIEYTGNTSLDVGAKVFAI
HHHHHHHHHHHHHCCCEEEECCCCHHCCCHHCCCCEEEECEEEEECCCCCCCCCEEEEEE
NHYTGEKRLVTRTVFSFVAIDENGKPKPINKITPATEKEKRIFDERLKEREERIKLSKNI
EECCCCHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
QESESCS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]