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The map label for this gene is atoB [C]

Identifier: 15920258

GI number: 15920258

Start: 101475

End: 102668

Strand: Direct

Name: atoB [C]

Synonym: ST0079

Alternate gene names: 15920258

Gene position: 101475-102668 (Clockwise)

Preceding gene: 15920256

Following gene: 15920259

Centisome position: 3.77

GC content: 40.03

Gene sequence:

>1194_bases
GTGAAAATGAGAAATGTAGCAATCATAGGTACTGGGCATACTAAGTTTGGCGTTAGGACTGACGTAAATCTTCAAGAATT
AGCATGGGAGGCTATAAAACAAGCGTTAGAAGAAGCTAATTTGGATCAAAAGGATATTCAGTATTTTGTTGTAGGAAATG
TTGGAAGTTGGAGTGCTGAAGAATTACCAGCAGTTGTTGTCGGAGAATATTCAGATTTAACTCCTAAAGGGACTATGAGA
GTGGAAGCCGCATGTGCTACGGGCAGTGCAGCATTAAGAGATGCCTATCTAGCAATTAAATCTGGTGAGGCTGATATAGC
TTTAGCTGTTGGTGTTGAACAAATGCATCAGTCTCCTAATCCTCAAGTTGTTGAATTAATAGGAAGGGCTGGTGATTATT
TCTGGGAATTTGAGAATTTCGGATTAACATTTCCGGGCTATTATGCTCTCCATGCTTCAGCTTATATGGCTAAATATGGA
GCAAAAGAAGAAGACTTAGGTAAAATTGCTATAAAAAGCCACCACTACGGAGCAAGGAATCCATATGCGCAATTCCAAAA
AGAAATTACAATGGATGAATATCTTAAATCTAAACCAGTAGCATATCCGTTGAAATTATTAGACTCTTCCCCAATCACTG
ATGGTGCCGCCGCTGTAGTTTTAGCATCTGAAGAAGTTGCCAAGAAAATTACTGATTCCCCAGTTTGGATTGTGTCACAA
GGTGTTGCTAGCGGTACAGCAAACTTAAGTAAGAGAACAGATTTTACACGTATAGAAGCTGCTTATTTAGCAGCTCAACA
AGCATATTCTAGGGCTGGTATTAATTTTGATGAGGCTTGGAGGTTTTTTGATGTAGCTGAAGTTCATGATTGTTTCACTA
TTGCTGAAATAATGGCTTATGAGGATTTGGGTTTTGCTAAGAGGGGTGAGGGATATCTATTAGCTAGAGAAGAACAGACG
TATATCGGTGGAAAGATACCAGTAAATGTTGATGGTGGGTTAAAAGCTAAAGGACACCCTATTGGCGCTACCGGTATTAG
TATGGCTGTATCTATAACAAGGCAATTGCTTTATAGGGCTCCTAAGGGTACACAGGTTGATGTAAAGCATGGCATGGGTA
TTTCACACAATGTGGGAGGAACAGGACACTACGCATACGTGACAATATTCTCGACAAGGAGGCCATCATCATGA

Upstream 100 bases:

>100_bases
TTCCAGATAAGTTCATCTTCATACAATCAATGCCTCTTACCTCAACAAATAAGATAGACAAAAAAATATTAAGAGATTTG
GCTAATAAGAGTATGTAGGT

Downstream 100 bases:

>100_bases
CTATAAATGATGTAAGAGAAAAATTACAACAACAAATTTCTCAATTAATTTCATCTTTAGATCAAGTTGTTCAAATGTAT
GGAATGCCAATTATTCAAGA

Product: acetyl-CoA acetyltransferase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MKMRNVAIIGTGHTKFGVRTDVNLQELAWEAIKQALEEANLDQKDIQYFVVGNVGSWSAEELPAVVVGEYSDLTPKGTMR
VEAACATGSAALRDAYLAIKSGEADIALAVGVEQMHQSPNPQVVELIGRAGDYFWEFENFGLTFPGYYALHASAYMAKYG
AKEEDLGKIAIKSHHYGARNPYAQFQKEITMDEYLKSKPVAYPLKLLDSSPITDGAAAVVLASEEVAKKITDSPVWIVSQ
GVASGTANLSKRTDFTRIEAAYLAAQQAYSRAGINFDEAWRFFDVAEVHDCFTIAEIMAYEDLGFAKRGEGYLLAREEQT
YIGGKIPVNVDGGLKAKGHPIGATGISMAVSITRQLLYRAPKGTQVDVKHGMGISHNVGGTGHYAYVTIFSTRRPSS

Sequences:

>Translated_397_residues
MKMRNVAIIGTGHTKFGVRTDVNLQELAWEAIKQALEEANLDQKDIQYFVVGNVGSWSAEELPAVVVGEYSDLTPKGTMR
VEAACATGSAALRDAYLAIKSGEADIALAVGVEQMHQSPNPQVVELIGRAGDYFWEFENFGLTFPGYYALHASAYMAKYG
AKEEDLGKIAIKSHHYGARNPYAQFQKEITMDEYLKSKPVAYPLKLLDSSPITDGAAAVVLASEEVAKKITDSPVWIVSQ
GVASGTANLSKRTDFTRIEAAYLAAQQAYSRAGINFDEAWRFFDVAEVHDCFTIAEIMAYEDLGFAKRGEGYLLAREEQT
YIGGKIPVNVDGGLKAKGHPIGATGISMAVSITRQLLYRAPKGTQVDVKHGMGISHNVGGTGHYAYVTIFSTRRPSS
>Mature_397_residues
MKMRNVAIIGTGHTKFGVRTDVNLQELAWEAIKQALEEANLDQKDIQYFVVGNVGSWSAEELPAVVVGEYSDLTPKGTMR
VEAACATGSAALRDAYLAIKSGEADIALAVGVEQMHQSPNPQVVELIGRAGDYFWEFENFGLTFPGYYALHASAYMAKYG
AKEEDLGKIAIKSHHYGARNPYAQFQKEITMDEYLKSKPVAYPLKLLDSSPITDGAAAVVLASEEVAKKITDSPVWIVSQ
GVASGTANLSKRTDFTRIEAAYLAAQQAYSRAGINFDEAWRFFDVAEVHDCFTIAEIMAYEDLGFAKRGEGYLLAREEQT
YIGGKIPVNVDGGLKAKGHPIGATGISMAVSITRQLLYRAPKGTQVDVKHGMGISHNVGGTGHYAYVTIFSTRRPSS

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=402, Percent_Identity=32.5870646766169, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI302344760, Length=400, Percent_Identity=31.25, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI302344767, Length=321, Percent_Identity=33.3333333333333, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI302344762, Length=389, Percent_Identity=29.8200514138817, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI55956775, Length=356, Percent_Identity=30.0561797752809, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17537653, Length=397, Percent_Identity=31.4861460957179, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24585051, Length=395, Percent_Identity=32.1518987341772, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI19921506, Length=395, Percent_Identity=31.6455696202532, Blast_Score=159, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 43182; Mature: 43182

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMRNVAIIGTGHTKFGVRTDVNLQELAWEAIKQALEEANLDQKDIQYFVVGNVGSWSAE
CCCCEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCHHHCEEEEEECCCCCCHH
ELPAVVVGEYSDLTPKGTMRVEAACATGSAALRDAYLAIKSGEADIALAVGVEQMHQSPN
HCCEEEEECCCCCCCCCCEEEEEECCCCCHHHHEEEEEEECCCCCEEEEECHHHHHCCCC
PQVVELIGRAGDYFWEFENFGLTFPGYYALHASAYMAKYGAKEEDLGKIAIKSHHYGARN
CHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCC
PYAQFQKEITMDEYLKSKPVAYPLKLLDSSPITDGAAAVVLASEEVAKKITDSPVWIVSQ
CHHHHHHHCCHHHHHHCCCCEEEHHHHCCCCCCCCCEEEEEECHHHHHHHCCCCEEEEEC
GVASGTANLSKRTDFTRIEAAYLAAQQAYSRAGINFDEAWRFFDVAEVHDCFTIAEIMAY
CCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EDLGFAKRGEGYLLAREEQTYIGGKIPVNVDGGLKAKGHPIGATGISMAVSITRQLLYRA
HCCCCCCCCCCEEEEECCCCEECCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
PKGTQVDVKHGMGISHNVGGTGHYAYVTIFSTRRPSS
CCCCEEEHHCCCCCCCCCCCCCCEEEEEEEECCCCCC
>Mature Secondary Structure
MKMRNVAIIGTGHTKFGVRTDVNLQELAWEAIKQALEEANLDQKDIQYFVVGNVGSWSAE
CCCCEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCHHHCEEEEEECCCCCCHH
ELPAVVVGEYSDLTPKGTMRVEAACATGSAALRDAYLAIKSGEADIALAVGVEQMHQSPN
HCCEEEEECCCCCCCCCCEEEEEECCCCCHHHHEEEEEEECCCCCEEEEECHHHHHCCCC
PQVVELIGRAGDYFWEFENFGLTFPGYYALHASAYMAKYGAKEEDLGKIAIKSHHYGARN
CHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCC
PYAQFQKEITMDEYLKSKPVAYPLKLLDSSPITDGAAAVVLASEEVAKKITDSPVWIVSQ
CHHHHHHHCCHHHHHHCCCCEEEHHHHCCCCCCCCCEEEEEECHHHHHHHCCCCEEEEEC
GVASGTANLSKRTDFTRIEAAYLAAQQAYSRAGINFDEAWRFFDVAEVHDCFTIAEIMAY
CCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EDLGFAKRGEGYLLAREEQTYIGGKIPVNVDGGLKAKGHPIGATGISMAVSITRQLLYRA
HCCCCCCCCCCEEEEECCCCEECCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
PKGTQVDVKHGMGISHNVGGTGHYAYVTIFSTRRPSS
CCCCEEEHHCCCCCCCCCCCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]