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The map label for this gene is guaAA [H]

Identifier: 159041768

GI number: 159041768

Start: 1268093

End: 1268659

Strand: Reverse

Name: guaAA [H]

Synonym: Cmaq_1203

Alternate gene names: 159041768

Gene position: 1268659-1268093 (Counterclockwise)

Preceding gene: 159041769

Following gene: 159041767

Centisome position: 61.06

GC content: 42.5

Gene sequence:

>567_bases
ATGGGTGTAATAGGTGTTGTTAATTTCGGCGGCCAATATAATCATTTGATTAAACGTAGGTTAGAGGACTTAGGCTTTCA
AGCCAAGTTCATTAACCCCAATGAACCAGTACAAGTACTTTCAAGGGAACTCAACTGCCTAATAATCAGTGGTGGGTCAT
GGAACATTCCAGCGGACATACCTAAGTTAGGTAATGCGCCTCAATACGCCTTAGAATTCCCAGGGCCGATTTTAGGCATA
TGTCTAGGTCATCAATTAATTGCATATGAGTTCGGCGGCATCCTAGGTAATAAAACACCTGAATTCGGGGGTGTTAGGAT
ACGTATCGATAATGAAGACACAATACTAAGAGGAATAGGGGCAGAGTTCACTGCCTGGGAAAGCCATAATATAAGTGTTG
ATAAGGAGCCAAATGGCTTCACAGTGCTTGCCCACAGTGATTTAGTTAGGGTTCAAGCCATGGCTAATCCAAGGATAGGT
AGATACAGTGTTCAATTCCACCCGGAGGTTAAACACACTGAGTTCGGTGACATTATTCTAAGGAACTTCGCTGAATTATG
TTCTTAG

Upstream 100 bases:

>100_bases
CTGAGCAAGTGTTATCAATGGTTAGGGAGAAGGCAACTGCACAGCCCATTGCCCCAGCTCAGCGTTAAGTTTAAATCCTA
ATTTATTGCGTTAACATTAA

Downstream 100 bases:

>100_bases
GTGTTGCTCCTTAATTATTATTGTGTTTATTTAAATAAATTAAGAAAATACCGGGTACTTTAACGCAATGTTTAAATCAC
GGTAAGCAAAGTAGGCTTAT

Product: glutamine amidotransferase class-I

Products: NA

Alternate protein names: Glutamine amidotransferase [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MGVIGVVNFGGQYNHLIKRRLEDLGFQAKFINPNEPVQVLSRELNCLIISGGSWNIPADIPKLGNAPQYALEFPGPILGI
CLGHQLIAYEFGGILGNKTPEFGGVRIRIDNEDTILRGIGAEFTAWESHNISVDKEPNGFTVLAHSDLVRVQAMANPRIG
RYSVQFHPEVKHTEFGDIILRNFAELCS

Sequences:

>Translated_188_residues
MGVIGVVNFGGQYNHLIKRRLEDLGFQAKFINPNEPVQVLSRELNCLIISGGSWNIPADIPKLGNAPQYALEFPGPILGI
CLGHQLIAYEFGGILGNKTPEFGGVRIRIDNEDTILRGIGAEFTAWESHNISVDKEPNGFTVLAHSDLVRVQAMANPRIG
RYSVQFHPEVKHTEFGDIILRNFAELCS
>Mature_187_residues
GVIGVVNFGGQYNHLIKRRLEDLGFQAKFINPNEPVQVLSRELNCLIISGGSWNIPADIPKLGNAPQYALEFPGPILGIC
LGHQLIAYEFGGILGNKTPEFGGVRIRIDNEDTILRGIGAEFTAWESHNISVDKEPNGFTVLAHSDLVRVQAMANPRIGR
YSVQFHPEVKHTEFGDIILRNFAELCS

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG0518

COG function: function code F; GMP synthase - Glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=187, Percent_Identity=34.2245989304813, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1788854, Length=196, Percent_Identity=31.1224489795918, Blast_Score=94, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6323873, Length=189, Percent_Identity=32.8042328042328, Blast_Score=96, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281365319, Length=190, Percent_Identity=30, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR004739 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 20766; Mature: 20635

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVIGVVNFGGQYNHLIKRRLEDLGFQAKFINPNEPVQVLSRELNCLIISGGSWNIPADI
CCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCEEEECCCCCCCCCCC
PKLGNAPQYALEFPGPILGICLGHQLIAYEFGGILGNKTPEFGGVRIRIDNEDTILRGIG
CCCCCCCCEEEECCCHHHHHHHCCCCEEHHHCCCCCCCCCCCCCEEEEECCCCEEEEECC
AEFTAWESHNISVDKEPNGFTVLAHSDLVRVQAMANPRIGRYSVQFHPEVKHTEFGDIIL
CCEEEECCCCEEECCCCCCEEEEEECCEEEEEEECCCCCCEEEEEECCCCCCCCHHHHHH
RNFAELCS
HHHHHHCC
>Mature Secondary Structure 
GVIGVVNFGGQYNHLIKRRLEDLGFQAKFINPNEPVQVLSRELNCLIISGGSWNIPADI
CEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCEEEECCCCCCCCCCC
PKLGNAPQYALEFPGPILGICLGHQLIAYEFGGILGNKTPEFGGVRIRIDNEDTILRGIG
CCCCCCCCEEEECCCHHHHHHHCCCCEEHHHCCCCCCCCCCCCCEEEEECCCCEEEEECC
AEFTAWESHNISVDKEPNGFTVLAHSDLVRVQAMANPRIGRYSVQFHPEVKHTEFGDIIL
CCEEEECCCCEEECCCCCCEEEEEECCEEEEEEECCCCCCEEEEEECCCCCCCCHHHHHH
RNFAELCS
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11427726 [H]