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The map label for this gene is hppA [H]

Identifier: 159041519

GI number: 159041519

Start: 995581

End: 997878

Strand: Reverse

Name: hppA [H]

Synonym: Cmaq_0949

Alternate gene names: 159041519

Gene position: 997878-995581 (Counterclockwise)

Preceding gene: 159041522

Following gene: 159041518

Centisome position: 48.03

GC content: 46.17

Gene sequence:

>2298_bases
ATGATTAACCCCCTGGTATTGGTTGGATTATTAACAGGCTTGGTGGGTATACTTATCTCCATCTTCATTTACCTATGGAT
CCAGAGACAGCCGCTTGGTGACGAGAACATGGTTAACGTGTGGAATGCAATAAGAGAGGGTGCTAAAGCATACATGAGGA
GACAAATAAGGACTATATTGCTCTTCTCAGCAGTGATATCAGTGGTAGTAGCCCTTAGTGTTTACGCTGGCTATAGTATT
AAGGTTCTACCCATGCACCCTGAGCTAAGGAGTGAGGTTACTCTTGAATCCACGTTAATTGGAGTATCCGTGCTACTAGG
TAGTGTAGCATCATTAACCACAGCGTTTCTAAGCATGGATGCCTCCACTAAGGCTAACGTGAGGACCACCGAAGCCGCCA
AGAGGGGTGTGAGACATGCCCTGAGGGTTGCTGTACTTGGTGGTAGTGTGCTTGGGTTCTCCGTACCATCGGTTAGCGTA
TTTGCATTGGCTCTACTCTTCATAGTTTACTCAATTATTGTAGAGGGAGCAACCACACCATTTAACCTAAGGGTTATCTT
AGATGGCCTAGCGGGCTTCGCGTTTGGGGCTAGTTTATCGGCATTATTCGCCCAAATAGGCGGTGGAATATACACTAAGG
CAGCGGATGTTGGTGCTGACCTCGTGGGTAAGGTTGAGGCTGGGATCCCTGAGGATGATCCAAGGAACCCAGCTGTAATA
GCTGATCAGGTTGGTGATAATGTCGGTGACTGCGCTGGGAGGGGTGCTGATATCTTTGAATCCGTTACAGCTGAGTTGCT
TGGAACAATGATAGTTGGTTGGACAGTATACTTCTTCCTAATTGAGGCAGGTTACCCCATTACTGAGGCCTTGAGCTTTG
TATTCCTACCATTCTTAACAGGGGCGGTTAGGGTTATTGCAACTGTCCCAGGGGTCTTGGTATCGGCTTATCAAGGTGAG
TTTAAGGATCCCATGGAGCCGTTGAGGAACGGCGTGATAGCATCAGCCGTAACCGCTATTGCTGGATTCTTCCTAATATA
CTACCTCCTAATGCCGAAGATTTGGGTTTACTTCTTCACAGCATCATTAACTGGAATAATAGCTGCAATAATAATAGTAC
TAGTGACTAACCACTACACGGGCAGGGAGGCTAAGCCCGTGATTGAGATTGCTGAGGTATCTAGGGTTAGCCCAGCGTTA
ACAATACTTCAAGGTTTAACAACAGGCATGAATGCAACCTTCATGCCAATAATAGTTATTGCAATAACCCTACTGGCATC
GTTTGCACTAGGCATGACCGCACCATTACCTGTGGTGATGAGTAACTACACCATAGGTAGTATTCCCATCGCTAAATTCA
TCTACGGCATATACGGTACAGCAGCAGCAACCCTAGGTATGTTATCCTTAGCTGGAATAATAATGACCCTTGATGGGGCA
GGTCCAATAACAGACAACGCCAGTGGCATAGCTGAGATGAGTGAATTAAGCCCAGAGGTTAGGGGTAGGCTTGATCCACT
GGATTCAATAGGTAATGTTACCAAGGCTCTCACTAAGGGTTACGCCATGGGTTCAGCGGCGTTAGCAGCGCTACTACTGT
TTCAAGCCTTCATACAGGATTATGTCGCTAGGAACCCAACCGTAATACAGGCCGCAGCCACTGATGTGTCACTCAACTTG
GGAAGCTTCATAAGTGTCATGGATTACCTCCTTAACCACCTAATGTTAATGAGGGCTGACATACTGGTAAGCGTCCTAAT
AGGCGCAATGTTACCCTTCCTTTTCAGTTCCTTAGCCTTAAGAGCCGTAACTAAGGCTGCATGGAGCATGGTTGAGGAGG
TTAGGAGGCAGTTCAGGGAAAAACCCGGGATACTGAGGGGTATTGAGAAACCTGATTATTATAGGGCAGTGGACATAAGT
ACGCAATTCGCGTTAAGAAACATGATAACGCCAACATTATCAGTAATACTAACACCCCTAATAATAGGATTACTGTTCGG
TGGACCGGCAGTGGGTGCTTTAGTAATAGGGGCAACCGCAAGCGGTATTGTATTAGCTATAACCATGATGTGGGGTGGTG
CGGCTTGGGATAACGCTAAGAAGTATATTGAGGCAGGGCATCTTGGGGGAAAGGGATCATCAACCCATGCTGCCGCAGTC
ATAGGTGACACTGTTGGTGACCCATTAAAAGATACTGCTGGACCATCACTACACATTGTTATTAAATTACTTAACACAAT
ATCATTAGTCTTCATACCGCTCTACATGATTTGGCTCCTTCAAGGCTTATTCCCATAA

Upstream 100 bases:

>100_bases
ATAATTATAGAATACAACTCACCCCTATCCATTATGTTTATTTCCACTAATTACACCATGCTGAGATAAAAAACACACCT
ACACTAATACCTGACCACAT

Downstream 100 bases:

>100_bases
AGCGCATTAATGATGTAAACCCTGTTAAAAATATTCATAATTCTTAACCAAGAACCAGTTAAATACAGTAGCATTAAGAA
TTAGGCAACAGTAAGGGATT

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound proton-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; H(+)-PPase [H]

Number of amino acids: Translated: 765; Mature: 765

Protein sequence:

>765_residues
MINPLVLVGLLTGLVGILISIFIYLWIQRQPLGDENMVNVWNAIREGAKAYMRRQIRTILLFSAVISVVVALSVYAGYSI
KVLPMHPELRSEVTLESTLIGVSVLLGSVASLTTAFLSMDASTKANVRTTEAAKRGVRHALRVAVLGGSVLGFSVPSVSV
FALALLFIVYSIIVEGATTPFNLRVILDGLAGFAFGASLSALFAQIGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVI
ADQVGDNVGDCAGRGADIFESVTAELLGTMIVGWTVYFFLIEAGYPITEALSFVFLPFLTGAVRVIATVPGVLVSAYQGE
FKDPMEPLRNGVIASAVTAIAGFFLIYYLLMPKIWVYFFTASLTGIIAAIIIVLVTNHYTGREAKPVIEIAEVSRVSPAL
TILQGLTTGMNATFMPIIVIAITLLASFALGMTAPLPVVMSNYTIGSIPIAKFIYGIYGTAAATLGMLSLAGIIMTLDGA
GPITDNASGIAEMSELSPEVRGRLDPLDSIGNVTKALTKGYAMGSAALAALLLFQAFIQDYVARNPTVIQAAATDVSLNL
GSFISVMDYLLNHLMLMRADILVSVLIGAMLPFLFSSLALRAVTKAAWSMVEEVRRQFREKPGILRGIEKPDYYRAVDIS
TQFALRNMITPTLSVILTPLIIGLLFGGPAVGALVIGATASGIVLAITMMWGGAAWDNAKKYIEAGHLGGKGSSTHAAAV
IGDTVGDPLKDTAGPSLHIVIKLLNTISLVFIPLYMIWLLQGLFP

Sequences:

>Translated_765_residues
MINPLVLVGLLTGLVGILISIFIYLWIQRQPLGDENMVNVWNAIREGAKAYMRRQIRTILLFSAVISVVVALSVYAGYSI
KVLPMHPELRSEVTLESTLIGVSVLLGSVASLTTAFLSMDASTKANVRTTEAAKRGVRHALRVAVLGGSVLGFSVPSVSV
FALALLFIVYSIIVEGATTPFNLRVILDGLAGFAFGASLSALFAQIGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVI
ADQVGDNVGDCAGRGADIFESVTAELLGTMIVGWTVYFFLIEAGYPITEALSFVFLPFLTGAVRVIATVPGVLVSAYQGE
FKDPMEPLRNGVIASAVTAIAGFFLIYYLLMPKIWVYFFTASLTGIIAAIIIVLVTNHYTGREAKPVIEIAEVSRVSPAL
TILQGLTTGMNATFMPIIVIAITLLASFALGMTAPLPVVMSNYTIGSIPIAKFIYGIYGTAAATLGMLSLAGIIMTLDGA
GPITDNASGIAEMSELSPEVRGRLDPLDSIGNVTKALTKGYAMGSAALAALLLFQAFIQDYVARNPTVIQAAATDVSLNL
GSFISVMDYLLNHLMLMRADILVSVLIGAMLPFLFSSLALRAVTKAAWSMVEEVRRQFREKPGILRGIEKPDYYRAVDIS
TQFALRNMITPTLSVILTPLIIGLLFGGPAVGALVIGATASGIVLAITMMWGGAAWDNAKKYIEAGHLGGKGSSTHAAAV
IGDTVGDPLKDTAGPSLHIVIKLLNTISLVFIPLYMIWLLQGLFP
>Mature_765_residues
MINPLVLVGLLTGLVGILISIFIYLWIQRQPLGDENMVNVWNAIREGAKAYMRRQIRTILLFSAVISVVVALSVYAGYSI
KVLPMHPELRSEVTLESTLIGVSVLLGSVASLTTAFLSMDASTKANVRTTEAAKRGVRHALRVAVLGGSVLGFSVPSVSV
FALALLFIVYSIIVEGATTPFNLRVILDGLAGFAFGASLSALFAQIGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVI
ADQVGDNVGDCAGRGADIFESVTAELLGTMIVGWTVYFFLIEAGYPITEALSFVFLPFLTGAVRVIATVPGVLVSAYQGE
FKDPMEPLRNGVIASAVTAIAGFFLIYYLLMPKIWVYFFTASLTGIIAAIIIVLVTNHYTGREAKPVIEIAEVSRVSPAL
TILQGLTTGMNATFMPIIVIAITLLASFALGMTAPLPVVMSNYTIGSIPIAKFIYGIYGTAAATLGMLSLAGIIMTLDGA
GPITDNASGIAEMSELSPEVRGRLDPLDSIGNVTKALTKGYAMGSAALAALLLFQAFIQDYVARNPTVIQAAATDVSLNL
GSFISVMDYLLNHLMLMRADILVSVLIGAMLPFLFSSLALRAVTKAAWSMVEEVRRQFREKPGILRGIEKPDYYRAVDIS
TQFALRNMITPTLSVILTPLIIGLLFGGPAVGALVIGATASGIVLAITMMWGGAAWDNAKKYIEAGHLGGKGSSTHAAAV
IGDTVGDPLKDTAGPSLHIVIKLLNTISLVFIPLYMIWLLQGLFP

Specific function: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 81017; Mature: 81017

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINPLVLVGLLTGLVGILISIFIYLWIQRQPLGDENMVNVWNAIREGAKAYMRRQIRTIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LFSAVISVVVALSVYAGYSIKVLPMHPELRSEVTLESTLIGVSVLLGSVASLTTAFLSMD
HHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ASTKANVRTTEAAKRGVRHALRVAVLGGSVLGFSVPSVSVFALALLFIVYSIIVEGATTP
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
FNLRVILDGLAGFAFGASLSALFAQIGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVI
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHCHHHHHHHHCCCCCCCCCCCCEE
ADQVGDNVGDCAGRGADIFESVTAELLGTMIVGWTVYFFLIEAGYPITEALSFVFLPFLT
HHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
GAVRVIATVPGVLVSAYQGEFKDPMEPLRNGVIASAVTAIAGFFLIYYLLMPKIWVYFFT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASLTGIIAAIIIVLVTNHYTGREAKPVIEIAEVSRVSPALTILQGLTTGMNATFMPIIVI
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AITLLASFALGMTAPLPVVMSNYTIGSIPIAKFIYGIYGTAAATLGMLSLAGIIMTLDGA
HHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
GPITDNASGIAEMSELSPEVRGRLDPLDSIGNVTKALTKGYAMGSAALAALLLFQAFIQD
CCCCCCCHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
YVARNPTVIQAAATDVSLNLGSFISVMDYLLNHLMLMRADILVSVLIGAMLPFLFSSLAL
HHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAVTKAAWSMVEEVRRQFREKPGILRGIEKPDYYRAVDISTQFALRNMITPTLSVILTPL
HHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHH
IIGLLFGGPAVGALVIGATASGIVLAITMMWGGAAWDNAKKYIEAGHLGGKGSSTHAAAV
HHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHE
IGDTVGDPLKDTAGPSLHIVIKLLNTISLVFIPLYMIWLLQGLFP
ECCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MINPLVLVGLLTGLVGILISIFIYLWIQRQPLGDENMVNVWNAIREGAKAYMRRQIRTIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LFSAVISVVVALSVYAGYSIKVLPMHPELRSEVTLESTLIGVSVLLGSVASLTTAFLSMD
HHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ASTKANVRTTEAAKRGVRHALRVAVLGGSVLGFSVPSVSVFALALLFIVYSIIVEGATTP
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
FNLRVILDGLAGFAFGASLSALFAQIGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVI
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHCHHHHHHHHCCCCCCCCCCCCEE
ADQVGDNVGDCAGRGADIFESVTAELLGTMIVGWTVYFFLIEAGYPITEALSFVFLPFLT
HHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
GAVRVIATVPGVLVSAYQGEFKDPMEPLRNGVIASAVTAIAGFFLIYYLLMPKIWVYFFT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASLTGIIAAIIIVLVTNHYTGREAKPVIEIAEVSRVSPALTILQGLTTGMNATFMPIIVI
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AITLLASFALGMTAPLPVVMSNYTIGSIPIAKFIYGIYGTAAATLGMLSLAGIIMTLDGA
HHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
GPITDNASGIAEMSELSPEVRGRLDPLDSIGNVTKALTKGYAMGSAALAALLLFQAFIQD
CCCCCCCHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
YVARNPTVIQAAATDVSLNLGSFISVMDYLLNHLMLMRADILVSVLIGAMLPFLFSSLAL
HHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAVTKAAWSMVEEVRRQFREKPGILRGIEKPDYYRAVDISTQFALRNMITPTLSVILTPL
HHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHH
IIGLLFGGPAVGALVIGATASGIVLAITMMWGGAAWDNAKKYIEAGHLGGKGSSTHAAAV
HHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHHE
IGDTVGDPLKDTAGPSLHIVIKLLNTISLVFIPLYMIWLLQGLFP
ECCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]