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The map label for this gene is cdd [H]

Identifier: 159041314

GI number: 159041314

Start: 772871

End: 773263

Strand: Reverse

Name: cdd [H]

Synonym: Cmaq_0740

Alternate gene names: 159041314

Gene position: 773263-772871 (Counterclockwise)

Preceding gene: 159041315

Following gene: 159041311

Centisome position: 37.22

GC content: 44.53

Gene sequence:

>393_bases
ATGGATGAGGAGGTTAATAGGGCTATTCAGTTGGCTGAATCATACTTAAGTAACTCATACTCACCCTACTCAGGTATTAA
GGTTGCTGCAGTTGCGATAACAAGTGATGGTAAAATGTTCCCAGGGGTTAATGTTGAGAACTCCTCATACGGCTTAACAA
TATGTGCTGAAAGGGTTGCAGTATTTAGGGCAGTCACAGAGGGTTATAGGAGGATTAAGGCTGTGGTTGTGGTTTCTAAC
CGTGATGAAATATACCCCTGTGGCGCCTGTCTACAGGTTATGGCTGAGTTTAATGTTGAGGAGGTTTATGTGGCTTCACG
AGGCGGCATTAAGAGGTTTAAGTTGAGTGAACTCTTACCAAGGCCCTTCAGTCTAGGAGCCCAGAGGACTTAA

Upstream 100 bases:

>100_bases
GAAGTCATGATACTTGCATCAGCATTACTATCAAGTGAAACCAAGGGTATTGAACTACAGTGATTACTACATTTAAAAAC
TCACTTGATTTAAAGTAAAC

Downstream 100 bases:

>100_bases
GAACCCTAAGGACGAGGCTTGGGAACCAGGGCTCTGAGGATAAGGGGCCGTTTAATTTAATTAAGGGGCATTTAACCTTA
ATAGTCTCTGCAGCCCTCTT

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MDEEVNRAIQLAESYLSNSYSPYSGIKVAAVAITSDGKMFPGVNVENSSYGLTICAERVAVFRAVTEGYRRIKAVVVVSN
RDEIYPCGACLQVMAEFNVEEVYVASRGGIKRFKLSELLPRPFSLGAQRT

Sequences:

>Translated_130_residues
MDEEVNRAIQLAESYLSNSYSPYSGIKVAAVAITSDGKMFPGVNVENSSYGLTICAERVAVFRAVTEGYRRIKAVVVVSN
RDEIYPCGACLQVMAEFNVEEVYVASRGGIKRFKLSELLPRPFSLGAQRT
>Mature_130_residues
MDEEVNRAIQLAESYLSNSYSPYSGIKVAAVAITSDGKMFPGVNVENSSYGLTICAERVAVFRAVTEGYRRIKAVVVVSN
RDEIYPCGACLQVMAEFNVEEVYVASRGGIKRFKLSELLPRPFSLGAQRT

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=125, Percent_Identity=40, Blast_Score=92, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17551074, Length=112, Percent_Identity=40.1785714285714, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17540514, Length=119, Percent_Identity=40.3361344537815, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323274, Length=112, Percent_Identity=38.3928571428571, Blast_Score=73, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582741, Length=134, Percent_Identity=35.8208955223881, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19920920, Length=124, Percent_Identity=37.0967741935484, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14293; Mature: 14293

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEEVNRAIQLAESYLSNSYSPYSGIKVAAVAITSDGKMFPGVNVENSSYGLTICAERVA
CCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
VFRAVTEGYRRIKAVVVVSNRDEIYPCGACLQVMAEFNVEEVYVASRGGIKRFKLSELLP
HHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHCCHHEEEEECCCCCCEEEHHHHCC
RPFSLGAQRT
CCCCCCCCCC
>Mature Secondary Structure
MDEEVNRAIQLAESYLSNSYSPYSGIKVAAVAITSDGKMFPGVNVENSSYGLTICAERVA
CCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
VFRAVTEGYRRIKAVVVVSNRDEIYPCGACLQVMAEFNVEEVYVASRGGIKRFKLSELLP
HHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHCCHHEEEEECCCCCCEEEHHHHCC
RPFSLGAQRT
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]