Click here to switch to the map view.

The map label for this gene is dapE [H]

Identifier: 159041134

GI number: 159041134

Start: 586568

End: 587809

Strand: Reverse

Name: dapE [H]

Synonym: Cmaq_0553

Alternate gene names: 159041134

Gene position: 587809-586568 (Counterclockwise)

Preceding gene: 159041141

Following gene: 159041132

Centisome position: 28.29

GC content: 44.93

Gene sequence:

>1242_bases
ATGGTTAGTGAACTGGGGGATCAGTTGGCTGAATTAACCTCACGTCTAGTTCAAATAAATAGCGTTAATCCACCTGGTGA
TGTAACCGGGGTTGTTGAATTCATTAGGAATTGGCTCAGTGAAAGGGGATTCTCAAGCAGTATTTACGAGTACGTTAAGG
GTAAGCCCAATTTAATAGCCAGGGTAGGTAAGGGTAAGCCTATAATCATACTGAATGGGCACACTGACGTCGTACCACCA
GGTGACCCAGATAAATGGACCCACCCACCCTTCTCAGGTAGGGTTATTGAAGGAAGGGTTTACGGGAGGGGTTCAACAGA
CATGAAGGGTGGGGTAGCCGTCATAATGATGGTTTTCGCTAAGTTAGGGCCATTAATTGAGAAGGAGGGTGCTGGTTCAT
TAGTCTTCTCCGCCACAGCTGATGAGGAAGTTGGTGGTCATGCCGGTGTTGAGGCCTTAGTTAAGGATAATTTACTAGTG
GGTGATGCAGCCATAGTTGCTGAACCAACAGGCTTCGATAAGTACTGCATAGCTGAGAAGGGGTTAAGCCAAGTGAAGTT
AATCACCAGGGGTAGGCCAGCCCACGGTAGCCTGCCTCTACTTGGTGATAATGCAATAATGAAGCTGTTCAAGGCTATTG
ATAAGGCCCAGGGCATTATTAATGAAGTGAACAGGGATATTAAGCTACCCCAGGATTTAATCGAAGCCGTTAATAATTCA
GCAAAGGTCTACCTGGAGGGGGCTTTAAGGAGCGGCCTAAGGTTAAGTGAGGATGATTTTAAACGCGTAATAGGCTCAGT
ATCCTTCAATCCAGGCGTAATTAAGGGTGGATCCAAGGTTAACATGGTTCCAGACTACGCGGAACTGGAATTAGACATGA
GGGTACCACCCGGTGTCTCACCAAGTGCCGTTATTGATAGGTTAAGGAACGGCTTAAGTGAATTAGCTGAAGTGGAGGTA
TTAGACACCAGTGAACCAAACTACACACCCTCCAATGAGAGGATAATTCAATTAATACGTGAAGGCATTAGTAGACAAGG
AGCTGAGGCTAAGCCAATAATAATGACTGGGGCAACCGACGGAAGGTACTTGAGACTAAGAGGCATACCAACGGTGATTT
ACGGACCAGGTGAATTAACATTAGCACACACTTATGATGAATACGTAACCATAAAGGACCTAGTGAACACTCATAACACC
ATAAAATACACTGTGGAGAAATACTTAAGTTTAAAGCAATAA

Upstream 100 bases:

>100_bases
TATTAGATTCTTTGAATTCATAGCCATATTATGTCATACTCCTCCACACTTTAAAGCATTACCTAGCAATACTTAAATTT
CCCCTATTTAATAGTTAATA

Downstream 100 bases:

>100_bases
AACATCAAAAATACCTAATAATTTGATTTAATATTTTTATTTGCTTATCTTCTTATCTTCTTCTTAATGCTATTATTGCT
GCTACTGCTGCTATGACTAT

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MVSELGDQLAELTSRLVQINSVNPPGDVTGVVEFIRNWLSERGFSSSIYEYVKGKPNLIARVGKGKPIIILNGHTDVVPP
GDPDKWTHPPFSGRVIEGRVYGRGSTDMKGGVAVIMMVFAKLGPLIEKEGAGSLVFSATADEEVGGHAGVEALVKDNLLV
GDAAIVAEPTGFDKYCIAEKGLSQVKLITRGRPAHGSLPLLGDNAIMKLFKAIDKAQGIINEVNRDIKLPQDLIEAVNNS
AKVYLEGALRSGLRLSEDDFKRVIGSVSFNPGVIKGGSKVNMVPDYAELELDMRVPPGVSPSAVIDRLRNGLSELAEVEV
LDTSEPNYTPSNERIIQLIREGISRQGAEAKPIIMTGATDGRYLRLRGIPTVIYGPGELTLAHTYDEYVTIKDLVNTHNT
IKYTVEKYLSLKQ

Sequences:

>Translated_413_residues
MVSELGDQLAELTSRLVQINSVNPPGDVTGVVEFIRNWLSERGFSSSIYEYVKGKPNLIARVGKGKPIIILNGHTDVVPP
GDPDKWTHPPFSGRVIEGRVYGRGSTDMKGGVAVIMMVFAKLGPLIEKEGAGSLVFSATADEEVGGHAGVEALVKDNLLV
GDAAIVAEPTGFDKYCIAEKGLSQVKLITRGRPAHGSLPLLGDNAIMKLFKAIDKAQGIINEVNRDIKLPQDLIEAVNNS
AKVYLEGALRSGLRLSEDDFKRVIGSVSFNPGVIKGGSKVNMVPDYAELELDMRVPPGVSPSAVIDRLRNGLSELAEVEV
LDTSEPNYTPSNERIIQLIREGISRQGAEAKPIIMTGATDGRYLRLRGIPTVIYGPGELTLAHTYDEYVTIKDLVNTHNT
IKYTVEKYLSLKQ
>Mature_413_residues
MVSELGDQLAELTSRLVQINSVNPPGDVTGVVEFIRNWLSERGFSSSIYEYVKGKPNLIARVGKGKPIIILNGHTDVVPP
GDPDKWTHPPFSGRVIEGRVYGRGSTDMKGGVAVIMMVFAKLGPLIEKEGAGSLVFSATADEEVGGHAGVEALVKDNLLV
GDAAIVAEPTGFDKYCIAEKGLSQVKLITRGRPAHGSLPLLGDNAIMKLFKAIDKAQGIINEVNRDIKLPQDLIEAVNNS
AKVYLEGALRSGLRLSEDDFKRVIGSVSFNPGVIKGGSKVNMVPDYAELELDMRVPPGVSPSAVIDRLRNGLSELAEVEV
LDTSEPNYTPSNERIIQLIREGISRQGAEAKPIIMTGATDGRYLRLRGIPTVIYGPGELTLAHTYDEYVTIKDLVNTHNT
IKYTVEKYLSLKQ

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Homo sapiens, GI4501901, Length=399, Percent_Identity=25.8145363408521, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1790395, Length=389, Percent_Identity=25.9640102827763, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1788816, Length=398, Percent_Identity=25.1256281407035, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789236, Length=173, Percent_Identity=26.0115606936416, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538640, Length=395, Percent_Identity=22.7848101265823, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24649206, Length=402, Percent_Identity=28.1094527363184, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24649202, Length=399, Percent_Identity=27.5689223057644, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24649204, Length=399, Percent_Identity=27.5689223057644, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24649210, Length=394, Percent_Identity=28.1725888324873, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24649212, Length=408, Percent_Identity=27.4509803921569, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21356353, Length=406, Percent_Identity=27.0935960591133, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24649208, Length=396, Percent_Identity=26.5151515151515, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 44712; Mature: 44712

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSELGDQLAELTSRLVQINSVNPPGDVTGVVEFIRNWLSERGFSSSIYEYVKGKPNLIA
CCHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEE
RVGKGKPIIILNGHTDVVPPGDPDKWTHPPFSGRVIEGRVYGRGSTDMKGGVAVIMMVFA
EECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHH
KLGPLIEKEGAGSLVFSATADEEVGGHAGVEALVKDNLLVGDAAIVAEPTGFDKYCIAEK
HHCCHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCEEECCEEEEECCCCCCCHHHHHC
GLSQVKLITRGRPAHGSLPLLGDNAIMKLFKAIDKAQGIINEVNRDIKLPQDLIEAVNNS
CHHHEEHEECCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCC
AKVYLEGALRSGLRLSEDDFKRVIGSVSFNPGVIKGGSKVNMVPDYAELELDMRVPPGVS
CEEEEEEHHHCCCCCCHHHHHHHHHCCCCCCCEEECCCEEEECCCHHHEEEEECCCCCCC
PSAVIDRLRNGLSELAEVEVLDTSEPNYTPSNERIIQLIREGISRQGAEAKPIIMTGATD
HHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCC
GRYLRLRGIPTVIYGPGELTLAHTYDEYVTIKDLVNTHNTIKYTVEKYLSLKQ
CCEEEEECCCEEEECCCCEEEEECCCHHEEHHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MVSELGDQLAELTSRLVQINSVNPPGDVTGVVEFIRNWLSERGFSSSIYEYVKGKPNLIA
CCHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEE
RVGKGKPIIILNGHTDVVPPGDPDKWTHPPFSGRVIEGRVYGRGSTDMKGGVAVIMMVFA
EECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHH
KLGPLIEKEGAGSLVFSATADEEVGGHAGVEALVKDNLLVGDAAIVAEPTGFDKYCIAEK
HHCCHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCEEECCEEEEECCCCCCCHHHHHC
GLSQVKLITRGRPAHGSLPLLGDNAIMKLFKAIDKAQGIINEVNRDIKLPQDLIEAVNNS
CHHHEEHEECCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCC
AKVYLEGALRSGLRLSEDDFKRVIGSVSFNPGVIKGGSKVNMVPDYAELELDMRVPPGVS
CEEEEEEHHHCCCCCCHHHHHHHHHCCCCCCCEEECCCEEEECCCHHHEEEEECCCCCCC
PSAVIDRLRNGLSELAEVEVLDTSEPNYTPSNERIIQLIREGISRQGAEAKPIIMTGATD
HHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCC
GRYLRLRGIPTVIYGPGELTLAHTYDEYVTIKDLVNTHNTIKYTVEKYLSLKQ
CCEEEEECCCEEEECCCCEEEEECCCHHEEHHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]