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The map label for this gene is atpB [H]

Identifier: 159040926

GI number: 159040926

Start: 382191

End: 383624

Strand: Reverse

Name: atpB [H]

Synonym: Cmaq_0342

Alternate gene names: 159040926

Gene position: 383624-382191 (Counterclockwise)

Preceding gene: 159040928

Following gene: 159040924

Centisome position: 18.47

GC content: 48.81

Gene sequence:

>1434_bases
ATGTCCAAGCTTCTTGAGATTAGGGGGATACAGGAGTATAGGACTGTTAGGGAGGTTAAGGGGCCTTTAATAGTTATTGA
GAGGACTAAGGGGATATCCTACGGTGAAATGGGTGTTGTAACTGGGCCTGATGGTGAACCCAGGCTTATTCAAGTCATAG
AGGTTGGACCTGACTACGCCATAGCCCAAGTCCTAACGGGCACATTAGGCTTACCGGCAAGTGGCTCAACGGTTAGATTC
TATGGAACCACCCTAAGGCTTCCGGTATCAGAGGATTTACTGGGTAGGATAATTAGCGGTAGGGGTGTGCCTAGGGATTC
ATTATCAATGCCTCCCGCGGAGGATTTCCTTGATGTTAACGGTGAACCACTTAACCCATACGCCAGGGATTACCCGGAGG
AACCCATTGAGACCGGTGTTAGTGCAATAGATGGACTCTACACCATGGTTAGGGGGCAGAAGTTACCCATATTCTCAGGC
ACTGGACTGCCCCATAATATGCTTGCAGCCCAAGTTGCTAGACAAGCCACGGTTAGGGGTAGTGAGGAGGAGTTCGCAAT
AGTCTTCGCGGCCATTGGGCTTAGGACCGAGGAGGCTTTATTCTTCATTGATGAGTTCAGGAGGACTGGTGCCTTGAGGA
GGCTGGTACTGGTAATGAACCTGGCCAGTGACCCAATAGCTGAGAGGATACTCACGCCTAGGGTTGCCTTAACCATAGCC
GAGTACTTGGCTTGGCAAAGGGATTACCATGTGTTAGTTATTCTAAGTGACATGCTTAATTACGCTGAGGCACTTAGGGA
GCTTTCATCAGCCAAGGGTGAATTACCCGGTAGGAGGGGTTACCCAGGCTACATGTACACTGATTTAGCCTCAATATTCG
AGAGGGCTGGTAGGGCTAGGGGTAGGAAGGGTAGTGTTACTCAATTCCCAATATTAACAATGCCTCACGACGACATAACC
CACCCAGTACCAGACTTAACAGGCTACATTACAGAGGGTCAATTAGTCCTATCAAGGTCAATGTGGGGTAAGGGTATTTA
CCCACCGTTCGATGTTTTAATGAGCCTATCAAGGCTTATGAAGGACGCCGTGGGTGAGGGGAAGACTAGGGATGATCATA
AGTACGTGGCTAACCAATTAATATCAGCATACTCAAGGGCCCTTGACGTCAGGAACCTAGCAGTACTGGTTGGTGAGGGT
AATTTAAGTTGGCGTGAAAGGAGGTACCTCAGGTTCGCTGATGAGTTTGAGAGGAGGTTCATAGCCCAGGGCTTCTATGA
GAGGAGAACCTTCGAACAGACGCTGGATATAGCCTGGGATGCCTTAAGCATTCTCCCAGATGATGAATTCTCCAACATAC
CACCGGAGGTGTCTAAGAGGTATTATAGGGAGGGGGTGTTTAAGTCGATTAAGGATGAGGGGGTTAAGGCTTAA

Upstream 100 bases:

>100_bases
AGTAAATCCTGAGGTATAACGCTCTTTAACTCATCCTTAAGCTTCATTTAACCGGTATTTGTGTTAATAGTTAAAAACTA
ATCACTGTACGGTTTAATTA

Downstream 100 bases:

>100_bases
GCAAATTAACCAATAATACTTAAAACTTACTTGGAAACAATCCTGATTCAACCGAGGATTAACTTAAGGTGTTTTAATTA
ACCCATGCATCAACATTACA

Product: V-type ATP synthase subunit B

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit B [H]

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MSKLLEIRGIQEYRTVREVKGPLIVIERTKGISYGEMGVVTGPDGEPRLIQVIEVGPDYAIAQVLTGTLGLPASGSTVRF
YGTTLRLPVSEDLLGRIISGRGVPRDSLSMPPAEDFLDVNGEPLNPYARDYPEEPIETGVSAIDGLYTMVRGQKLPIFSG
TGLPHNMLAAQVARQATVRGSEEEFAIVFAAIGLRTEEALFFIDEFRRTGALRRLVLVMNLASDPIAERILTPRVALTIA
EYLAWQRDYHVLVILSDMLNYAEALRELSSAKGELPGRRGYPGYMYTDLASIFERAGRARGRKGSVTQFPILTMPHDDIT
HPVPDLTGYITEGQLVLSRSMWGKGIYPPFDVLMSLSRLMKDAVGEGKTRDDHKYVANQLISAYSRALDVRNLAVLVGEG
NLSWRERRYLRFADEFERRFIAQGFYERRTFEQTLDIAWDALSILPDDEFSNIPPEVSKRYYREGVFKSIKDEGVKA

Sequences:

>Translated_477_residues
MSKLLEIRGIQEYRTVREVKGPLIVIERTKGISYGEMGVVTGPDGEPRLIQVIEVGPDYAIAQVLTGTLGLPASGSTVRF
YGTTLRLPVSEDLLGRIISGRGVPRDSLSMPPAEDFLDVNGEPLNPYARDYPEEPIETGVSAIDGLYTMVRGQKLPIFSG
TGLPHNMLAAQVARQATVRGSEEEFAIVFAAIGLRTEEALFFIDEFRRTGALRRLVLVMNLASDPIAERILTPRVALTIA
EYLAWQRDYHVLVILSDMLNYAEALRELSSAKGELPGRRGYPGYMYTDLASIFERAGRARGRKGSVTQFPILTMPHDDIT
HPVPDLTGYITEGQLVLSRSMWGKGIYPPFDVLMSLSRLMKDAVGEGKTRDDHKYVANQLISAYSRALDVRNLAVLVGEG
NLSWRERRYLRFADEFERRFIAQGFYERRTFEQTLDIAWDALSILPDDEFSNIPPEVSKRYYREGVFKSIKDEGVKA
>Mature_476_residues
SKLLEIRGIQEYRTVREVKGPLIVIERTKGISYGEMGVVTGPDGEPRLIQVIEVGPDYAIAQVLTGTLGLPASGSTVRFY
GTTLRLPVSEDLLGRIISGRGVPRDSLSMPPAEDFLDVNGEPLNPYARDYPEEPIETGVSAIDGLYTMVRGQKLPIFSGT
GLPHNMLAAQVARQATVRGSEEEFAIVFAAIGLRTEEALFFIDEFRRTGALRRLVLVMNLASDPIAERILTPRVALTIAE
YLAWQRDYHVLVILSDMLNYAEALRELSSAKGELPGRRGYPGYMYTDLASIFERAGRARGRKGSVTQFPILTMPHDDITH
PVPDLTGYITEGQLVLSRSMWGKGIYPPFDVLMSLSRLMKDAVGEGKTRDDHKYVANQLISAYSRALDVRNLAVLVGEGN
LSWRERRYLRFADEFERRFIAQGFYERRTFEQTLDIAWDALSILPDDEFSNIPPEVSKRYYREGVFKSIKDEGVKA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit [H]

COG id: COG1156

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit B

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI19913428, Length=458, Percent_Identity=54.1484716157205, Blast_Score=501, Evalue=1e-142,
Organism=Homo sapiens, GI19913426, Length=467, Percent_Identity=53.1049250535332, Blast_Score=497, Evalue=1e-140,
Organism=Homo sapiens, GI32189394, Length=374, Percent_Identity=27.0053475935829, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI50345984, Length=309, Percent_Identity=26.8608414239482, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4757810, Length=309, Percent_Identity=26.8608414239482, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI19913424, Length=312, Percent_Identity=25.3205128205128, Blast_Score=93, Evalue=4e-19,
Organism=Escherichia coli, GI1788251, Length=360, Percent_Identity=30.8333333333333, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1790172, Length=313, Percent_Identity=26.1980830670927, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1790170, Length=348, Percent_Identity=26.1494252873563, Blast_Score=105, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17570191, Length=459, Percent_Identity=52.723311546841, Blast_Score=494, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17510931, Length=459, Percent_Identity=51.4161220043573, Blast_Score=480, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI25144756, Length=395, Percent_Identity=26.8354430379747, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17565854, Length=375, Percent_Identity=24.5333333333333, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71988080, Length=295, Percent_Identity=26.4406779661017, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71988063, Length=295, Percent_Identity=26.4406779661017, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71988074, Length=235, Percent_Identity=26.8085106382979, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6319603, Length=458, Percent_Identity=54.8034934497817, Blast_Score=506, Evalue=1e-144,
Organism=Saccharomyces cerevisiae, GI6322581, Length=394, Percent_Identity=27.1573604060914, Blast_Score=122, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6319370, Length=304, Percent_Identity=28.2894736842105, Blast_Score=104, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6320016, Length=224, Percent_Identity=28.125, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281361666, Length=461, Percent_Identity=51.8438177874187, Blast_Score=483, Evalue=1e-136,
Organism=Drosophila melanogaster, GI24646341, Length=461, Percent_Identity=51.8438177874187, Blast_Score=483, Evalue=1e-136,
Organism=Drosophila melanogaster, GI17136796, Length=461, Percent_Identity=51.8438177874187, Blast_Score=483, Evalue=1e-136,
Organism=Drosophila melanogaster, GI24638766, Length=395, Percent_Identity=27.0886075949367, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24658560, Length=321, Percent_Identity=27.4143302180685, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI28574560, Length=366, Percent_Identity=27.0491803278689, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24583992, Length=311, Percent_Identity=25.7234726688103, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24583988, Length=311, Percent_Identity=25.7234726688103, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24583986, Length=311, Percent_Identity=25.7234726688103, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24583984, Length=311, Percent_Identity=25.7234726688103, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20129479, Length=312, Percent_Identity=25.6410256410256, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022879 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: 3.6.3.14

Molecular weight: Translated: 53392; Mature: 53261

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLLEIRGIQEYRTVREVKGPLIVIERTKGISYGEMGVVTGPDGEPRLIQVIEVGPDYA
CCCCHHHCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEECCCCCCCEEEEEECCCCHH
IAQVLTGTLGLPASGSTVRFYGTTLRLPVSEDLLGRIISGRGVPRDSLSMPPAEDFLDVN
HHHHHHHHCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHCCC
GEPLNPYARDYPEEPIETGVSAIDGLYTMVRGQKLPIFSGTGLPHNMLAAQVARQATVRG
CCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHCCC
SEEEFAIVFAAIGLRTEEALFFIDEFRRTGALRRLVLVMNLASDPIAERILTPRVALTIA
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHH
EYLAWQRDYHVLVILSDMLNYAEALRELSSAKGELPGRRGYPGYMYTDLASIFERAGRAR
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
GRKGSVTQFPILTMPHDDITHPVPDLTGYITEGQLVLSRSMWGKGIYPPFDVLMSLSRLM
CCCCCCCCCEEEECCCCCCCCCCCCHHCEECCCEEEEEHHHCCCCCCCHHHHHHHHHHHH
KDAVGEGKTRDDHKYVANQLISAYSRALDVRNLAVLVGEGNLSWRERRYLRFADEFERRF
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
IAQGFYERRTFEQTLDIAWDALSILPDDEFSNIPPEVSKRYYREGVFKSIKDEGVKA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SKLLEIRGIQEYRTVREVKGPLIVIERTKGISYGEMGVVTGPDGEPRLIQVIEVGPDYA
CCCHHHCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEECCCCCCCEEEEEECCCCHH
IAQVLTGTLGLPASGSTVRFYGTTLRLPVSEDLLGRIISGRGVPRDSLSMPPAEDFLDVN
HHHHHHHHCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHCCC
GEPLNPYARDYPEEPIETGVSAIDGLYTMVRGQKLPIFSGTGLPHNMLAAQVARQATVRG
CCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHCCC
SEEEFAIVFAAIGLRTEEALFFIDEFRRTGALRRLVLVMNLASDPIAERILTPRVALTIA
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHH
EYLAWQRDYHVLVILSDMLNYAEALRELSSAKGELPGRRGYPGYMYTDLASIFERAGRAR
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
GRKGSVTQFPILTMPHDDITHPVPDLTGYITEGQLVLSRSMWGKGIYPPFDVLMSLSRLM
CCCCCCCCCEEEECCCCCCCCCCCCHHCEECCCEEEEEHHHCCCCCCCHHHHHHHHHHHH
KDAVGEGKTRDDHKYVANQLISAYSRALDVRNLAVLVGEGNLSWRERRYLRFADEFERRF
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
IAQGFYERRTFEQTLDIAWDALSILPDDEFSNIPPEVSKRYYREGVFKSIKDEGVKA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; Diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines various reactions catalyzed by ATPase, analogs; Oligomycin; Quercetin; Trialkyl tinderivatives; Venturicidin [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11792869 [H]