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The map label for this gene is map [H]

Identifier: 159040752

GI number: 159040752

Start: 193319

End: 194233

Strand: Reverse

Name: map [H]

Synonym: Cmaq_0165

Alternate gene names: 159040752

Gene position: 194233-193319 (Counterclockwise)

Preceding gene: 159040753

Following gene: 159040749

Centisome position: 9.35

GC content: 42.3

Gene sequence:

>915_bases
ATGCTGAGTGAAGATGCCTTAAGAAAGTATAGGCAGGCTGGTGACATTATTCACAAGGTGCTTAAACACACCATTGATAA
GGTTCACCCAGGTATGAGTATACTGGAGTTATGTAATATGATTGAGGGTGAAATTAGGGATAGTGGTGCCTTACCAGCCT
TCCCAGCTAACATTGATGTTAATAATGTTGCAGCCCACTACACTGCTAAGATAGGTGATGAAGCGGTAATACCACCTAAC
TCAGTGGTTAAGATAGATGTGGGAGCCCACATTGATGGATACATCGTTGACTCAGCTGTCACAGTATACTTCAATAATGC
CTACTCAATGCTAACTAAGGCTGCCTGGACAGCCCTCAGGAATGCCCTTGATACAGCTAAGGCTGGTGTTGAGTTAAGTA
GGATTGGGGCTATTGTGGATAAGACCATTAGTAGCTTCGGCTTCAAGCCCATTAGAAACCTAACAGGCCACTTAATAAGT
AGGTACAGGTTGCATGCAGGTAAGTCAGTGCCTAATTACGATGATGGTAGTAGGGTTAAGATGCTTAATGGTGAAGTATA
CGCCATAGAACCCTTCGCAACCAATGGTAGAGGTATAGTTACTGATGCCCCTGAGGTAACAATATACATGCTGTTGAAGA
CTAATGTTAAGAAGCTTACCGAGGAGGCTAATTCAGCATTAAACTACATTTCAAGGAACTTTAACCAACTCCCCTTCACC
CCTAGGTGGTTGGTTGAGGAATTTAAGGATAAGACAATGAGCATTATTAATGAGCTTACTAGAAGGGGTGCCTTATATGG
GTACAATGTATTAATGGAGAGTGGTAATGGTTTTGTGGCTCAATTCGAGGACACGGTAATAGTGACCCAAGATGGTGTAG
AACCCTTAGCCAAAGTTCTTGAGTTAATTAACTAA

Upstream 100 bases:

>100_bases
GGTGAGGGTGTTTACATACTCATGGTTAAGAATCAAGCCTCAACATAATTAGAATAGTGAAGCGGGTTAAGTATATTAAA
TACGTGAACTTAAGCTCATT

Downstream 100 bases:

>100_bases
ACTACCTATTACCCACTGGCCTTCCAAGAACCTTAGCTAAACCACGCTTAATCCTCCTTGATCTACCGTAACCACAGGCA
GCGCAGTAGCCTTTAACAAT

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MLSEDALRKYRQAGDIIHKVLKHTIDKVHPGMSILELCNMIEGEIRDSGALPAFPANIDVNNVAAHYTAKIGDEAVIPPN
SVVKIDVGAHIDGYIVDSAVTVYFNNAYSMLTKAAWTALRNALDTAKAGVELSRIGAIVDKTISSFGFKPIRNLTGHLIS
RYRLHAGKSVPNYDDGSRVKMLNGEVYAIEPFATNGRGIVTDAPEVTIYMLLKTNVKKLTEEANSALNYISRNFNQLPFT
PRWLVEEFKDKTMSIINELTRRGALYGYNVLMESGNGFVAQFEDTVIVTQDGVEPLAKVLELIN

Sequences:

>Translated_304_residues
MLSEDALRKYRQAGDIIHKVLKHTIDKVHPGMSILELCNMIEGEIRDSGALPAFPANIDVNNVAAHYTAKIGDEAVIPPN
SVVKIDVGAHIDGYIVDSAVTVYFNNAYSMLTKAAWTALRNALDTAKAGVELSRIGAIVDKTISSFGFKPIRNLTGHLIS
RYRLHAGKSVPNYDDGSRVKMLNGEVYAIEPFATNGRGIVTDAPEVTIYMLLKTNVKKLTEEANSALNYISRNFNQLPFT
PRWLVEEFKDKTMSIINELTRRGALYGYNVLMESGNGFVAQFEDTVIVTQDGVEPLAKVLELIN
>Mature_304_residues
MLSEDALRKYRQAGDIIHKVLKHTIDKVHPGMSILELCNMIEGEIRDSGALPAFPANIDVNNVAAHYTAKIGDEAVIPPN
SVVKIDVGAHIDGYIVDSAVTVYFNNAYSMLTKAAWTALRNALDTAKAGVELSRIGAIVDKTISSFGFKPIRNLTGHLIS
RYRLHAGKSVPNYDDGSRVKMLNGEVYAIEPFATNGRGIVTDAPEVTIYMLLKTNVKKLTEEANSALNYISRNFNQLPFT
PRWLVEEFKDKTMSIINELTRRGALYGYNVLMESGNGFVAQFEDTVIVTQDGVEPLAKVLELIN

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI5803092, Length=303, Percent_Identity=35.3135313531353, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI124494254, Length=320, Percent_Identity=27.5, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17544396, Length=304, Percent_Identity=32.8947368421053, Blast_Score=174, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17542840, Length=332, Percent_Identity=28.6144578313253, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319380, Length=312, Percent_Identity=33.3333333333333, Blast_Score=166, Evalue=3e-42,
Organism=Drosophila melanogaster, GI17137568, Length=304, Percent_Identity=33.2236842105263, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24658585, Length=328, Percent_Identity=26.5243902439024, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002468
- InterPro:   IPR018349
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 33532; Mature: 33532

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSEDALRKYRQAGDIIHKVLKHTIDKVHPGMSILELCNMIEGEIRDSGALPAFPANIDV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NNVAAHYTAKIGDEAVIPPNSVVKIDVGAHIDGYIVDSAVTVYFNNAYSMLTKAAWTALR
CHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEECCEEEEEECCHHHHHHHHHHHHHH
NALDTAKAGVELSRIGAIVDKTISSFGFKPIRNLTGHLISRYRLHAGKSVPNYDDGSRVK
HHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
MLNGEVYAIEPFATNGRGIVTDAPEVTIYMLLKTNVKKLTEEANSALNYISRNFNQLPFT
EECCEEEEEECCCCCCCEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PRWLVEEFKDKTMSIINELTRRGALYGYNVLMESGNGFVAQFEDTVIVTQDGVEPLAKVL
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCEEEEECCCHHHHHHHH
ELIN
HHHC
>Mature Secondary Structure
MLSEDALRKYRQAGDIIHKVLKHTIDKVHPGMSILELCNMIEGEIRDSGALPAFPANIDV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NNVAAHYTAKIGDEAVIPPNSVVKIDVGAHIDGYIVDSAVTVYFNNAYSMLTKAAWTALR
CHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEECCEEEEEECCHHHHHHHHHHHHHH
NALDTAKAGVELSRIGAIVDKTISSFGFKPIRNLTGHLISRYRLHAGKSVPNYDDGSRVK
HHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
MLNGEVYAIEPFATNGRGIVTDAPEVTIYMLLKTNVKKLTEEANSALNYISRNFNQLPFT
EECCEEEEEECCCCCCCEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PRWLVEEFKDKTMSIINELTRRGALYGYNVLMESGNGFVAQFEDTVIVTQDGVEPLAKVL
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCEEEEECCCHHHHHHHH
ELIN
HHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8899719; 11427726 [H]