Click here to switch to the map view.

The map label for this gene is tdcB [H]

Identifier: 159040717

GI number: 159040717

Start: 152638

End: 153669

Strand: Reverse

Name: tdcB [H]

Synonym: Cmaq_0128

Alternate gene names: 159040717

Gene position: 153669-152638 (Counterclockwise)

Preceding gene: 159040718

Following gene: 159040712

Centisome position: 7.4

GC content: 42.73

Gene sequence:

>1032_bases
ATGAGTATTAATGTAGGTGTTAATAAATCCATTGATTTAATGCCCCTCATTCAGGAGGCTTGGGAATTCACCAGAAGGAT
GGAATCAATGGGTTACGTGATTAGAACCCCCCTGTATAGGTCAGAGCGACTATCAAGTAATGGCTTAAATGTCTACTTAA
AACTGGAGAATCTACAGAGGAGCGGTAGTTTCAAGGTTAGGGGTGTATTCTTTGCCGTCCATAAGTATATGCGTGACGGT
TATGAGCACTTCCTAACGGTATCTACTGGCAATCACGCTGTTGCTCTGGCATACGTAGCCAGCATATTGAGAGTCAGGGC
TACCGTGGTTGTTCCTGAGACCACGCAGAGGTCTAAGGTCGAGGATATGGAGAGATATGGTGCTGAGGTTATTAAGTATG
GTAGGTCGTACGTTGAAGCTGAGAAGAAGGCTCTCGAGATTTCCTCAAGTGATCAGAGGATTAAACTTATACATACATTT
AATGATTACTATGTAATTGCTGGACATACAACCATTGGACTTGAGATACTTGAGGATTTACCCAACGTTGACGCCATACT
TATACCGCTTGGTGGTGGTGCTTTACCGGCTGGTGTCTCCTACTTAGTAAGGCATGTTAAGCCAAGTACTAAGGTTTATG
GAGTACAACCTGAAAATGCACCATTTTATGTACTATCACTTAAGGAGGGTAAACCTGTGGTGCTTAGTAGCATTGAAACT
ATCGCTGACGGACTTGCCTCTAGACCTGGCGAGATACCCTTTGAATACATAAGGCGTTACCTAGATGGCGTGCTCTTAGT
TAATGAGCGTGACATTGAGAGAGCTGTATACGTATTGCTTAAGTATGAACATGTAATTGCCGAGGGGGCTGGCGCTATAG
CAATAGGGCCTATAATAAATGGTGACTTAGTTAAGAAGCTTGGTCAAGGCGGTGTTTATAATGTAGTTGCTGTAATAACA
GGCAGCCACATTGATGTAGAGAGGTTAAGGAAAATACTTGAAAATGAGAAAGCTTATGAAGGCAGAACTTAA

Upstream 100 bases:

>100_bases
TAGGACGAAGGCAATAGACCAGATAATGGAGGAAATAAAGAGATAACGGCATGGTGAGGTTAATTTAAAGCTTAAAAATA
TACTTTATTCATGATTTACA

Downstream 100 bases:

>100_bases
TACAGCGTATATTATCCAGCGCCAACACTTTATGCTGACTTTTAACGTGAGTCCCTGCTCATAATTGCATTAATCGTCAT
TAGTAGCACATCTTAATTAA

Product: pyridoxal-5'-phosphate-dependent protein subunit beta

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSINVGVNKSIDLMPLIQEAWEFTRRMESMGYVIRTPLYRSERLSSNGLNVYLKLENLQRSGSFKVRGVFFAVHKYMRDG
YEHFLTVSTGNHAVALAYVASILRVRATVVVPETTQRSKVEDMERYGAEVIKYGRSYVEAEKKALEISSSDQRIKLIHTF
NDYYVIAGHTTIGLEILEDLPNVDAILIPLGGGALPAGVSYLVRHVKPSTKVYGVQPENAPFYVLSLKEGKPVVLSSIET
IADGLASRPGEIPFEYIRRYLDGVLLVNERDIERAVYVLLKYEHVIAEGAGAIAIGPIINGDLVKKLGQGGVYNVVAVIT
GSHIDVERLRKILENEKAYEGRT

Sequences:

>Translated_343_residues
MSINVGVNKSIDLMPLIQEAWEFTRRMESMGYVIRTPLYRSERLSSNGLNVYLKLENLQRSGSFKVRGVFFAVHKYMRDG
YEHFLTVSTGNHAVALAYVASILRVRATVVVPETTQRSKVEDMERYGAEVIKYGRSYVEAEKKALEISSSDQRIKLIHTF
NDYYVIAGHTTIGLEILEDLPNVDAILIPLGGGALPAGVSYLVRHVKPSTKVYGVQPENAPFYVLSLKEGKPVVLSSIET
IADGLASRPGEIPFEYIRRYLDGVLLVNERDIERAVYVLLKYEHVIAEGAGAIAIGPIINGDLVKKLGQGGVYNVVAVIT
GSHIDVERLRKILENEKAYEGRT
>Mature_342_residues
SINVGVNKSIDLMPLIQEAWEFTRRMESMGYVIRTPLYRSERLSSNGLNVYLKLENLQRSGSFKVRGVFFAVHKYMRDGY
EHFLTVSTGNHAVALAYVASILRVRATVVVPETTQRSKVEDMERYGAEVIKYGRSYVEAEKKALEISSSDQRIKLIHTFN
DYYVIAGHTTIGLEILEDLPNVDAILIPLGGGALPAGVSYLVRHVKPSTKVYGVQPENAPFYVLSLKEGKPVVLSSIETI
ADGLASRPGEIPFEYIRRYLDGVLLVNERDIERAVYVLLKYEHVIAEGAGAIAIGPIINGDLVKKLGQGGVYNVVAVITG
SHIDVERLRKILENEKAYEGRT

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=297, Percent_Identity=32.3232323232323, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI33469958, Length=148, Percent_Identity=36.4864864864865, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI19923959, Length=146, Percent_Identity=34.9315068493151, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1789505, Length=324, Percent_Identity=33.9506172839506, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1790207, Length=264, Percent_Identity=34.8484848484849, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI2367138, Length=271, Percent_Identity=26.1992619926199, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71991565, Length=314, Percent_Identity=34.0764331210191, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17537387, Length=313, Percent_Identity=36.1022364217252, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17508781, Length=240, Percent_Identity=30.4166666666667, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6322631, Length=328, Percent_Identity=31.0975609756098, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6320930, Length=315, Percent_Identity=30.1587301587302, Blast_Score=109, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6319788, Length=318, Percent_Identity=28.6163522012579, Blast_Score=93, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21355833, Length=317, Percent_Identity=32.807570977918, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24645328, Length=233, Percent_Identity=30.4721030042918, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 38189; Mature: 38057

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINVGVNKSIDLMPLIQEAWEFTRRMESMGYVIRTPLYRSERLSSNGLNVYLKLENLQR
CEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCHHHHCCCCCCCEEEEEEECCCC
SGSFKVRGVFFAVHKYMRDGYEHFLTVSTGNHAVALAYVASILRVRATVVVPETTQRSKV
CCCEEEEHHHHHHHHHHHCCHHEEEEEECCCCCHHHHHHHHHHHHHEEEEECCCCCHHHH
EDMERYGAEVIKYGRSYVEAEKKALEISSSDQRIKLIHTFNDYYVIAGHTTIGLEILEDL
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEECCEEEEECCCCHHHHHHHCC
PNVDAILIPLGGGALPAGVSYLVRHVKPSTKVYGVQPENAPFYVLSLKEGKPVVLSSIET
CCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHH
IADGLASRPGEIPFEYIRRYLDGVLLVNERDIERAVYVLLKYEHVIAEGAGAIAIGPIIN
HHHHHHCCCCCCCHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
GDLVKKLGQGGVYNVVAVITGSHIDVERLRKILENEKAYEGRT
CHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SINVGVNKSIDLMPLIQEAWEFTRRMESMGYVIRTPLYRSERLSSNGLNVYLKLENLQR
EEECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCHHHHCCCCCCCEEEEEEECCCC
SGSFKVRGVFFAVHKYMRDGYEHFLTVSTGNHAVALAYVASILRVRATVVVPETTQRSKV
CCCEEEEHHHHHHHHHHHCCHHEEEEEECCCCCHHHHHHHHHHHHHEEEEECCCCCHHHH
EDMERYGAEVIKYGRSYVEAEKKALEISSSDQRIKLIHTFNDYYVIAGHTTIGLEILEDL
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEECCEEEEECCCCHHHHHHHCC
PNVDAILIPLGGGALPAGVSYLVRHVKPSTKVYGVQPENAPFYVLSLKEGKPVVLSSIET
CCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHH
IADGLASRPGEIPFEYIRRYLDGVLLVNERDIERAVYVLLKYEHVIAEGAGAIAIGPIIN
HHHHHHCCCCCCCHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
GDLVKKLGQGGVYNVVAVITGSHIDVERLRKILENEKAYEGRT
CHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA