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The map label for this gene is argF [H]

Identifier: 159040684

GI number: 159040684

Start: 109829

End: 110770

Strand: Reverse

Name: argF [H]

Synonym: Cmaq_0092

Alternate gene names: 159040684

Gene position: 110770-109829 (Counterclockwise)

Preceding gene: 159040685

Following gene: 159040682

Centisome position: 5.33

GC content: 44.69

Gene sequence:

>942_bases
ATGTTGAATCAATTAAGGGGTAGGAGCCTACTCAGTTGGCTTGACTACACTCCACAGGAGGTATTAATGCTGCTTAATCT
GTCTAAAAATATGAAGGAGAGGTATTACTTGGGTGAAAGGTACATTGGTGTCCACCAGGGTAAGACGCTACTCATGGTAT
TTGAGAAGCCTAGTACAAGGACAAGGATTAGTTTTGAAACTGCTGCTTGGCAACTCGGCATGAAGACTATTTACAGTAAT
CCCCAGGAGCTTCAGTTAGGTAGGGGGGAGACTGTTGAGGATACTGCTAGGGTTGTTTCAAGGATTGTTGACGGTATAGT
AGCCAGGGTCTTCAACCACTCAACATTAATCAAACTCACCCAGCACTCCCAAGTACCTGTTGTGAATGCCCTAAGTGATG
AATGCCACCCAACCCAGGTGCTTGCGGATGCGTTAACGTTATGGGAGGTTAAAGGTAAGGTTAATGGCATTAAATTAGCC
TTCGTAGGTGATGGGGATAATAACATGGCCCATAGCCTAATTGCAATAGGAGCCAGGTTAGGATGGGATATTAGGATAGT
ATCCCCTAAGAGGTACTGGCCAAGTAGAAGGTACATTGAGGATGCTGAGGATTTAGGTAAAAGAACAGGTGCAGTACTCA
CTGTTACGGAAACCATTGAGGAGGGGGTTAAGGGTGTTGATGCAGTGTACACTGATGTATGGGTATCAATGGGTATGGAG
AAGGAGGCTGAGGAGAGAATGAAGCTGCTTAAACCATATCAAGTAAACCAAGGTTTAATGAATATTGCAGGGGAGAACGC
AGTATTCATGCATTGTCTACCAGCCCATAGGGGTCTTGAGGTCACTGATGATGTAATTGACTCATCTAAAAGTGTTGTGT
GGCAGCAGGCTGAGAATAGGCTTCACACGGCTAAGGCCATATTAGCTGCATTGATTAGGTAA

Upstream 100 bases:

>100_bases
ATTAAGCGACCTATACTATGACCCAATCCTGGACTCCACTGAAGTCATACCGTAGGCGTTAAGGAATAATACTTAATAGT
GTGGGTGGATTTAATAAAGC

Downstream 100 bases:

>100_bases
GGTAAACTGATTTAAATAAGGGAATGCGATTAATTCTTAAGATTTAAAACACTATATTAACTTATATGCTTTAACCATGA
ACTGCCTAATCTTAGGCATG

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MLNQLRGRSLLSWLDYTPQEVLMLLNLSKNMKERYYLGERYIGVHQGKTLLMVFEKPSTRTRISFETAAWQLGMKTIYSN
PQELQLGRGETVEDTARVVSRIVDGIVARVFNHSTLIKLTQHSQVPVVNALSDECHPTQVLADALTLWEVKGKVNGIKLA
FVGDGDNNMAHSLIAIGARLGWDIRIVSPKRYWPSRRYIEDAEDLGKRTGAVLTVTETIEEGVKGVDAVYTDVWVSMGME
KEAEERMKLLKPYQVNQGLMNIAGENAVFMHCLPAHRGLEVTDDVIDSSKSVVWQQAENRLHTAKAILAALIR

Sequences:

>Translated_313_residues
MLNQLRGRSLLSWLDYTPQEVLMLLNLSKNMKERYYLGERYIGVHQGKTLLMVFEKPSTRTRISFETAAWQLGMKTIYSN
PQELQLGRGETVEDTARVVSRIVDGIVARVFNHSTLIKLTQHSQVPVVNALSDECHPTQVLADALTLWEVKGKVNGIKLA
FVGDGDNNMAHSLIAIGARLGWDIRIVSPKRYWPSRRYIEDAEDLGKRTGAVLTVTETIEEGVKGVDAVYTDVWVSMGME
KEAEERMKLLKPYQVNQGLMNIAGENAVFMHCLPAHRGLEVTDDVIDSSKSVVWQQAENRLHTAKAILAALIR
>Mature_313_residues
MLNQLRGRSLLSWLDYTPQEVLMLLNLSKNMKERYYLGERYIGVHQGKTLLMVFEKPSTRTRISFETAAWQLGMKTIYSN
PQELQLGRGETVEDTARVVSRIVDGIVARVFNHSTLIKLTQHSQVPVVNALSDECHPTQVLADALTLWEVKGKVNGIKLA
FVGDGDNNMAHSLIAIGARLGWDIRIVSPKRYWPSRRYIEDAEDLGKRTGAVLTVTETIEEGVKGVDAVYTDVWVSMGME
KEAEERMKLLKPYQVNQGLMNIAGENAVFMHCLPAHRGLEVTDDVIDSSKSVVWQQAENRLHTAKAILAALIR

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=309, Percent_Identity=38.5113268608414, Blast_Score=224, Evalue=9e-59,
Organism=Homo sapiens, GI18105007, Length=322, Percent_Identity=27.0186335403727, Blast_Score=99, Evalue=6e-21,
Organism=Escherichia coli, GI1790703, Length=327, Percent_Identity=40.9785932721713, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1786469, Length=333, Percent_Identity=40.2402402402402, Blast_Score=248, Evalue=4e-67,
Organism=Escherichia coli, GI2367364, Length=277, Percent_Identity=30.3249097472924, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193204318, Length=327, Percent_Identity=25.6880733944954, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322373, Length=319, Percent_Identity=31.974921630094, Blast_Score=180, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6322331, Length=316, Percent_Identity=28.4810126582279, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24642586, Length=320, Percent_Identity=24.375, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 35202; Mature: 35202

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNQLRGRSLLSWLDYTPQEVLMLLNLSKNMKERYYLGERYIGVHQGKTLLMVFEKPSTR
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCC
TRISFETAAWQLGMKTIYSNPQELQLGRGETVEDTARVVSRIVDGIVARVFNHSTLIKLT
EEEEEHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
QHSQVPVVNALSDECHPTQVLADALTLWEVKGKVNGIKLAFVGDGDNNMAHSLIAIGARL
CCCCCCEEHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHC
GWDIRIVSPKRYWPSRRYIEDAEDLGKRTGAVLTVTETIEEGVKGVDAVYTDVWVSMGME
CCEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCC
KEAEERMKLLKPYQVNQGLMNIAGENAVFMHCLPAHRGLEVTDDVIDSSKSVVWQQAENR
HHHHHHHHHHCCHHHCCHHHHHCCCCEEEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHH
LHTAKAILAALIR
HHHHHHHHHHHCC
>Mature Secondary Structure
MLNQLRGRSLLSWLDYTPQEVLMLLNLSKNMKERYYLGERYIGVHQGKTLLMVFEKPSTR
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCC
TRISFETAAWQLGMKTIYSNPQELQLGRGETVEDTARVVSRIVDGIVARVFNHSTLIKLT
EEEEEHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
QHSQVPVVNALSDECHPTQVLADALTLWEVKGKVNGIKLAFVGDGDNNMAHSLIAIGARL
CCCCCCEEHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHC
GWDIRIVSPKRYWPSRRYIEDAEDLGKRTGAVLTVTETIEEGVKGVDAVYTDVWVSMGME
CCEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCC
KEAEERMKLLKPYQVNQGLMNIAGENAVFMHCLPAHRGLEVTDDVIDSSKSVVWQQAENR
HHHHHHHHHHCCHHHCCHHHHHCCCCEEEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHH
LHTAKAILAALIR
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA