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The map label for this gene is dgoD [H]

Identifier: 159040666

GI number: 159040666

Start: 87718

End: 88905

Strand: Reverse

Name: dgoD [H]

Synonym: Cmaq_0074

Alternate gene names: 159040666

Gene position: 88905-87718 (Counterclockwise)

Preceding gene: 159040668

Following gene: 159040665

Centisome position: 4.28

GC content: 46.13

Gene sequence:

>1188_bases
ATGCCGGAGATAAGTGAAGTGGAGCCTATAATACTATATAACCCTAGGCCTGATGACCCAGCGCCTTGGGCGTCATATAT
GGTTTTAGTTAGGGTTGTTACTAAGGATGGTGGAGTTGGTTGGGGGGAAACTCTTAGTTCGATTAGAGTTAATGCATTGG
TTCAATTAATTAAGGTATTATCCAGTGTCATGAGGGGTAGGGATGTGTTTAACCTTGAGGGTAATAGGCTTGAGTGGTAT
AGACAGGACTTCAATATGCCTGTTTCCCTAGAGTCCACAGCCGCCTATAGTGCTTTTGATATTGCTTCATGGGACATAAT
AGGTAGGGAGCTTGGTGCACCGGTGCATAGGTTGCTTGGGGGCTTAACTAGGGATAGGGTTAGGGTTTATGCTAATGGCT
GGTATTCAAATGCAGTTAAGCCTGAGGATTTCGCTGAGAAGGCTAAGGAGACTGTTAGGAGGGGTTATACGGCTCTTAAA
TTCGACCCCTTTGGCCCATACTTCGACATGATTGATTCGGCAGGCATTAAGGATGCCGCTGAGAGGGTTAAGGCTGTTAG
GGAGGCTGTTGGTGATGGAGTGGACATACTCATTGAAGCCCACGGTAGGTTTAACGCTGAGTCAGCAATTAGGGCAGCGT
GGGCTTTGGAGCCCTATAACCCATTATTCATGGAAGAGCCCGTTCACCCAGAGGATATTGAGGGCTTAATTAGGTTTAGG
AACAGTACTAGAATTAGGGTTGCCTTAGGTGAACGCATAATTAATAAGGGATACTTAATTCAATACCTTAAACTCAGCCT
TGTTGATTACCTACAGACTGATGTGGGCAGATTCGGTGGCCTAACTGAAGCTAGAAAGGCATCAATAATGGCTGAAGCCT
TCAGTGTACCCATGGCATTTCACAACGCTAACGGCCCAATACTCCACGCAGCCACAATACAGCTTGATGCATCAATACCC
AACTTCGCCGTTCAGGAATCATTCTACGATTACTGGCCCCAGTGGAAGAGGGATCTTGTGGGTGACTCAATGCCTGTGGA
GAATGGTTACGTTAAGGTTCCCACTAAGCCTGGTTTAGGGGTTGATGTTAATGAGAAGCTTATTGAGAGGCTTAGGATTA
ATGAGACTGAGATTACCATTAAGGGTGGTTTATCGTGGATTGTTAAGGGGACCACTGGTGGCTCCTAG

Upstream 100 bases:

>100_bases
TACTGCATCATTGATGCATGTTCTTCTTAACATTGGATTCCACGTTTTTATACTTAGTTGCATACGGAATGGTTTAAAAA
ACGCATTGTGAAGCATAGGC

Downstream 100 bases:

>100_bases
TGAGACTACGTGGGCTTAAAGGTATACGAATTGGAATTAAATGAAGATAATGTTATTAAACCAAGGCAGGTAACTAATGT
ATGCAGCGTCAAATCCCAGT

Product: mandelate racemase/muconate lactonizing protein

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MPEISEVEPIILYNPRPDDPAPWASYMVLVRVVTKDGGVGWGETLSSIRVNALVQLIKVLSSVMRGRDVFNLEGNRLEWY
RQDFNMPVSLESTAAYSAFDIASWDIIGRELGAPVHRLLGGLTRDRVRVYANGWYSNAVKPEDFAEKAKETVRRGYTALK
FDPFGPYFDMIDSAGIKDAAERVKAVREAVGDGVDILIEAHGRFNAESAIRAAWALEPYNPLFMEEPVHPEDIEGLIRFR
NSTRIRVALGERIINKGYLIQYLKLSLVDYLQTDVGRFGGLTEARKASIMAEAFSVPMAFHNANGPILHAATIQLDASIP
NFAVQESFYDYWPQWKRDLVGDSMPVENGYVKVPTKPGLGVDVNEKLIERLRINETEITIKGGLSWIVKGTTGGS

Sequences:

>Translated_395_residues
MPEISEVEPIILYNPRPDDPAPWASYMVLVRVVTKDGGVGWGETLSSIRVNALVQLIKVLSSVMRGRDVFNLEGNRLEWY
RQDFNMPVSLESTAAYSAFDIASWDIIGRELGAPVHRLLGGLTRDRVRVYANGWYSNAVKPEDFAEKAKETVRRGYTALK
FDPFGPYFDMIDSAGIKDAAERVKAVREAVGDGVDILIEAHGRFNAESAIRAAWALEPYNPLFMEEPVHPEDIEGLIRFR
NSTRIRVALGERIINKGYLIQYLKLSLVDYLQTDVGRFGGLTEARKASIMAEAFSVPMAFHNANGPILHAATIQLDASIP
NFAVQESFYDYWPQWKRDLVGDSMPVENGYVKVPTKPGLGVDVNEKLIERLRINETEITIKGGLSWIVKGTTGGS
>Mature_394_residues
PEISEVEPIILYNPRPDDPAPWASYMVLVRVVTKDGGVGWGETLSSIRVNALVQLIKVLSSVMRGRDVFNLEGNRLEWYR
QDFNMPVSLESTAAYSAFDIASWDIIGRELGAPVHRLLGGLTRDRVRVYANGWYSNAVKPEDFAEKAKETVRRGYTALKF
DPFGPYFDMIDSAGIKDAAERVKAVREAVGDGVDILIEAHGRFNAESAIRAAWALEPYNPLFMEEPVHPEDIEGLIRFRN
STRIRVALGERIINKGYLIQYLKLSLVDYLQTDVGRFGGLTEARKASIMAEAFSVPMAFHNANGPILHAATIQLDASIPN
FAVQESFYDYWPQWKRDLVGDSMPVENGYVKVPTKPGLGVDVNEKLIERLRINETEITIKGGLSWIVKGTTGGS

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Homo sapiens, GI42544119, Length=326, Percent_Identity=23.0061349693252, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI48994953, Length=350, Percent_Identity=30.8571428571429, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787864, Length=372, Percent_Identity=26.0752688172043, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI226510960, Length=275, Percent_Identity=27.6363636363636, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 44096; Mature: 43965

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEISEVEPIILYNPRPDDPAPWASYMVLVRVVTKDGGVGWGETLSSIRVNALVQLIKVL
CCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHH
SSVMRGRDVFNLEGNRLEWYRQDFNMPVSLESTAAYSAFDIASWDIIGRELGAPVHRLLG
HHHHCCCEEEECCCCCHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHCHHHHHHHC
GLTRDRVRVYANGWYSNAVKPEDFAEKAKETVRRGYTALKFDPFGPYFDMIDSAGIKDAA
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCHHHH
ERVKAVREAVGDGVDILIEAHGRFNAESAIRAAWALEPYNPLFMEEPVHPEDIEGLIRFR
HHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHC
NSTRIRVALGERIINKGYLIQYLKLSLVDYLQTDVGRFGGLTEARKASIMAEAFSVPMAF
CCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEE
HNANGPILHAATIQLDASIPNFAVQESFYDYWPQWKRDLVGDSMPVENGYVKVPTKPGLG
ECCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCC
VDVNEKLIERLRINETEITIKGGLSWIVKGTTGGS
CCCCHHHHHHHCCCCEEEEEECCEEEEEECCCCCC
>Mature Secondary Structure 
PEISEVEPIILYNPRPDDPAPWASYMVLVRVVTKDGGVGWGETLSSIRVNALVQLIKVL
CCCCCCCCEEEECCCCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHH
SSVMRGRDVFNLEGNRLEWYRQDFNMPVSLESTAAYSAFDIASWDIIGRELGAPVHRLLG
HHHHCCCEEEECCCCCHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHCHHHHHHHC
GLTRDRVRVYANGWYSNAVKPEDFAEKAKETVRRGYTALKFDPFGPYFDMIDSAGIKDAA
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCHHHH
ERVKAVREAVGDGVDILIEAHGRFNAESAIRAAWALEPYNPLFMEEPVHPEDIEGLIRFR
HHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHC
NSTRIRVALGERIINKGYLIQYLKLSLVDYLQTDVGRFGGLTEARKASIMAEAFSVPMAF
CCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEE
HNANGPILHAATIQLDASIPNFAVQESFYDYWPQWKRDLVGDSMPVENGYVKVPTKPGLG
ECCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCC
VDVNEKLIERLRINETEITIKGGLSWIVKGTTGGS
CCCCHHHHHHHCCCCEEEEEECCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA