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The map label for this gene is trxA [H]

Identifier: 159040636

GI number: 159040636

Start: 59379

End: 59798

Strand: Reverse

Name: trxA [H]

Synonym: Cmaq_0044

Alternate gene names: 159040636

Gene position: 59798-59379 (Counterclockwise)

Preceding gene: 159040637

Following gene: 159040635

Centisome position: 2.88

GC content: 42.14

Gene sequence:

>420_bases
ATGGGGGAATTCATGGCTAATGATGTTGACAAAGACCCTGAATTAGATAAGCTACTTGAAAGGAAGGCTAGGGAAATGAT
TAAGAACGTTAACAATACTGGTGGTGTAGTGGAGTTGAATCGCAGTAACTTTGATGAATTCATTAAGACTCATGAAGTTG
CTGTAGTTGACTTCTGGGCCACCTGGTGCGCCCCCTGCTTCATGCTTGAGCCAATAATAAAGAGACTGGCTGCTGAGATG
CCTAATGTGGGTTTCGGTAGACTTAATACTGAAGAGGAACCTGAAATTGCGGCTAAATACTACGTTATGAGTCTACCAAC
AGTCATAATTTTCAAGAACGGTGAACCAATCGACCAGGTAATAGGTGTGGTGCCTAAGAAGATTCTTCAAGATAGGATTA
AGGCTTACCTCAATGACTAG

Upstream 100 bases:

>100_bases
TCCATTAAGTGGAGTTGATAATGCTCTGAATAACAGTGTTGCCGCGTATAGATTACTGAAGGGTAGTGGTTGACGGAAAA
AGGCTTATTAAATACTAGGC

Downstream 100 bases:

>100_bases
GTGAGTTAAATGTATCCCATACTTCTTGGAATAAACGGTATTGGTTACGGTAGTTTCACGGAATGTGAACTTAATGCATT
ACCGAGACTCATGAATATTG

Product: thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MGEFMANDVDKDPELDKLLERKAREMIKNVNNTGGVVELNRSNFDEFIKTHEVAVVDFWATWCAPCFMLEPIIKRLAAEM
PNVGFGRLNTEEEPEIAAKYYVMSLPTVIIFKNGEPIDQVIGVVPKKILQDRIKAYLND

Sequences:

>Translated_139_residues
MGEFMANDVDKDPELDKLLERKAREMIKNVNNTGGVVELNRSNFDEFIKTHEVAVVDFWATWCAPCFMLEPIIKRLAAEM
PNVGFGRLNTEEEPEIAAKYYVMSLPTVIIFKNGEPIDQVIGVVPKKILQDRIKAYLND
>Mature_138_residues
GEFMANDVDKDPELDKLLERKAREMIKNVNNTGGVVELNRSNFDEFIKTHEVAVVDFWATWCAPCFMLEPIIKRLAAEMP
NVGFGRLNTEEEPEIAAKYYVMSLPTVIIFKNGEPIDQVIGVVPKKILQDRIKAYLND

Specific function: Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI95113651, Length=83, Percent_Identity=37.3493975903614, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788936, Length=94, Percent_Identity=39.3617021276596, Blast_Score=79, Evalue=8e-17,
Organism=Escherichia coli, GI87082331, Length=104, Percent_Identity=34.6153846153846, Blast_Score=75, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71980562, Length=107, Percent_Identity=32.7102803738318, Blast_Score=73, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71980565, Length=98, Percent_Identity=33.6734693877551, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17507705, Length=107, Percent_Identity=31.7757009345794, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17507915, Length=93, Percent_Identity=35.4838709677419, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323072, Length=89, Percent_Identity=39.3258426966292, Blast_Score=82, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319925, Length=86, Percent_Identity=37.2093023255814, Blast_Score=76, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321648, Length=92, Percent_Identity=35.8695652173913, Blast_Score=76, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17648013, Length=87, Percent_Identity=35.632183908046, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24583090, Length=87, Percent_Identity=35.632183908046, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 15861; Mature: 15729

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEFMANDVDKDPELDKLLERKAREMIKNVNNTGGVVELNRSNFDEFIKTHEVAVVDFWA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
TWCAPCFMLEPIIKRLAAEMPNVGFGRLNTEEEPEIAAKYYVMSLPTVIIFKNGEPIDQV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCHHHH
IGVVPKKILQDRIKAYLND
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GEFMANDVDKDPELDKLLERKAREMIKNVNNTGGVVELNRSNFDEFIKTHEVAVVDFWA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
TWCAPCFMLEPIIKRLAAEMPNVGFGRLNTEEEPEIAAKYYVMSLPTVIIFKNGEPIDQV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCHHHH
IGVVPKKILQDRIKAYLND
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA