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The map label for this gene is aspB-4 [C]

Identifier: 15899942

GI number: 15899942

Start: 2986787

End: 2987929

Strand: Direct

Name: aspB-4 [C]

Synonym: SSO3245

Alternate gene names: 15899942

Gene position: 2986787-2987929 (Clockwise)

Preceding gene: 15899941

Following gene: 15899944

Centisome position: 99.82

GC content: 36.57

Gene sequence:

>1143_bases
TTGGTATCGAGAATCGGAAAAGAAATAGAGATTTCACCAGTCGAATTAGGATCACAAATAGCTAAAAGAGTTAAAATTAA
CATGGCCAGCGGGACGCCGGATCCTAGGAAAATGCCAATAAAGGAAATTAAAGATGCATATAGTGAAGTCTTGAACGAAC
TAGGTCCGAAGGTATTATTTTACCCCGGAGCTGGAGGACAAGAAGAGCTCATACGAGAGATAGAAGATAAATTCTTGAGT
GTTCTAAACTTAACTAAGAGGAAAGATGAGAAAATAGTTGTAACAAGTGGAGCACAACATGCCATGGAATTGCTAGGCAA
ATACTTCCTAGAGAACGATGTTATAGCTGTTGAGAATCCAACTTTCATAGAAACTTTTAACGCACTAAAATTGAGAAGTT
CCTCTGTAATTCCAATATCTTTGGATCCCTCAGGGATTGATGTAAATGAGCTCGAAACCTTACTGAAAGTTGTGAAGATT
AGATTATTATATGTTATTCCAAATTGTCATAACCCTGCCGGAGTTAACATGTCTGAATGTAGAAGAAAGAGACTAATTGA
ATTGGCCGAGAAATACGACTTCTATATTATAGAGGATGATCCATATAGACCAATAGCGGGGGAAACTCCACAACCGATAA
AGAACTACGACAATAACGGCAGAGTAATATACGTTAGTAGCTTCAGTAAAATAATAGCACCAGGATTAAGAGTGGGATTC
CTCATAGCAAAGGAAGATATAGCTGAAAAAATTAGCTTAATGGAACAATTAGACTTCTCTACATCGACCATAAACCAATA
TGTAGTGGCTAGATTATTAAGAAAGGGGGTTGTAACTGAAAGATCAAAAGAGCTTTATGAGCATTATAAAAGTAAGATGA
AGATATTAGTAGACTCTCTCGTAGATAAAGGATTAGACAAGTTTAATGAACCTAAGTGTGGTTTCTTTCTGCTCCTAGAT
GTTGGAAAAGATAGTTGGAACGTTTTTCATAAGGCTGTAGAAAAAGGCCTAAGTTTTGTTCCAGCAAAACCTTTCTTTTT
GAGAGGAGGAGATACCATGGCAAGACTGAGCGTGTCAGTTGCGACTAAAGAAGAAATAATTGAGGGAGTCAAAATCCTTA
ATGAAGTCATAAGAAATATTTAA

Upstream 100 bases:

>100_bases
AATCTGTAGGTATAGGTCTTGAAGATTTAGCGGTAGGGAAACTCATCTATGAAAAAGCTTTAAGCAAAGGTTTAGGTACT
GAAATAGAGGTAAAGGGAGT

Downstream 100 bases:

>100_bases
CCAAATACAACTTCTTCTACTCTAGAAATAAAATCCTTTACTTGATTCTCATAAAGTGGGATATCGTCTTCATCTACATT
CCCACTTAAATAACAATCGT

Product: aspartate aminotransferase (aspB-4)

Products: oxaloacetate; L-glutamate

Alternate protein names: AspB-1 [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MVSRIGKEIEISPVELGSQIAKRVKINMASGTPDPRKMPIKEIKDAYSEVLNELGPKVLFYPGAGGQEELIREIEDKFLS
VLNLTKRKDEKIVVTSGAQHAMELLGKYFLENDVIAVENPTFIETFNALKLRSSSVIPISLDPSGIDVNELETLLKVVKI
RLLYVIPNCHNPAGVNMSECRRKRLIELAEKYDFYIIEDDPYRPIAGETPQPIKNYDNNGRVIYVSSFSKIIAPGLRVGF
LIAKEDIAEKISLMEQLDFSTSTINQYVVARLLRKGVVTERSKELYEHYKSKMKILVDSLVDKGLDKFNEPKCGFFLLLD
VGKDSWNVFHKAVEKGLSFVPAKPFFLRGGDTMARLSVSVATKEEIIEGVKILNEVIRNI

Sequences:

>Translated_380_residues
MVSRIGKEIEISPVELGSQIAKRVKINMASGTPDPRKMPIKEIKDAYSEVLNELGPKVLFYPGAGGQEELIREIEDKFLS
VLNLTKRKDEKIVVTSGAQHAMELLGKYFLENDVIAVENPTFIETFNALKLRSSSVIPISLDPSGIDVNELETLLKVVKI
RLLYVIPNCHNPAGVNMSECRRKRLIELAEKYDFYIIEDDPYRPIAGETPQPIKNYDNNGRVIYVSSFSKIIAPGLRVGF
LIAKEDIAEKISLMEQLDFSTSTINQYVVARLLRKGVVTERSKELYEHYKSKMKILVDSLVDKGLDKFNEPKCGFFLLLD
VGKDSWNVFHKAVEKGLSFVPAKPFFLRGGDTMARLSVSVATKEEIIEGVKILNEVIRNI
>Mature_380_residues
MVSRIGKEIEISPVELGSQIAKRVKINMASGTPDPRKMPIKEIKDAYSEVLNELGPKVLFYPGAGGQEELIREIEDKFLS
VLNLTKRKDEKIVVTSGAQHAMELLGKYFLENDVIAVENPTFIETFNALKLRSSSVIPISLDPSGIDVNELETLLKVVKI
RLLYVIPNCHNPAGVNMSECRRKRLIELAEKYDFYIIEDDPYRPIAGETPQPIKNYDNNGRVIYVSSFSKIIAPGLRVGF
LIAKEDIAEKISLMEQLDFSTSTINQYVVARLLRKGVVTERSKELYEHYKSKMKILVDSLVDKGLDKFNEPKCGFFLLLD
VGKDSWNVFHKAVEKGLSFVPAKPFFLRGGDTMARLSVSVATKEEIIEGVKILNEVIRNI

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=408, Percent_Identity=26.9607843137255, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI33469970, Length=408, Percent_Identity=26.9607843137255, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1790797, Length=306, Percent_Identity=30.0653594771242, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1787710, Length=367, Percent_Identity=26.7029972752044, Blast_Score=111, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6321236, Length=395, Percent_Identity=25.8227848101266, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6321929, Length=304, Percent_Identity=25.6578947368421, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321000, Length=172, Percent_Identity=30.8139534883721, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356535, Length=396, Percent_Identity=26.010101010101, Blast_Score=105, Evalue=5e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 42795; Mature: 42795

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSRIGKEIEISPVELGSQIAKRVKINMASGTPDPRKMPIKEIKDAYSEVLNELGPKVLF
CCCCCCCCEEECHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEE
YPGAGGQEELIREIEDKFLSVLNLTKRKDEKIVVTSGAQHAMELLGKYFLENDVIAVENP
ECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCEEEECCC
TFIETFNALKLRSSSVIPISLDPSGIDVNELETLLKVVKIRLLYVIPNCHNPAGVNMSEC
CHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHH
RRKRLIELAEKYDFYIIEDDPYRPIAGETPQPIKNYDNNGRVIYVSSFSKIIAPGLRVGF
HHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHCCCCCCCEEEEECCHHHHCCCHHHEE
LIAKEDIAEKISLMEQLDFSTSTINQYVVARLLRKGVVTERSKELYEHYKSKMKILVDSL
EEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
VDKGLDKFNEPKCGFFLLLDVGKDSWNVFHKAVEKGLSFVPAKPFFLRGGDTMARLSVSV
HHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCEEHEEEHH
ATKEEIIEGVKILNEVIRNI
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSRIGKEIEISPVELGSQIAKRVKINMASGTPDPRKMPIKEIKDAYSEVLNELGPKVLF
CCCCCCCCEEECHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEE
YPGAGGQEELIREIEDKFLSVLNLTKRKDEKIVVTSGAQHAMELLGKYFLENDVIAVENP
ECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCEEEECCC
TFIETFNALKLRSSSVIPISLDPSGIDVNELETLLKVVKIRLLYVIPNCHNPAGVNMSEC
CHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHH
RRKRLIELAEKYDFYIIEDDPYRPIAGETPQPIKNYDNNGRVIYVSSFSKIIAPGLRVGF
HHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHCCCCCCCEEEEECCHHHHCCCHHHEE
LIAKEDIAEKISLMEQLDFSTSTINQYVVARLLRKGVVTERSKELYEHYKSKMKILVDSL
EEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
VDKGLDKFNEPKCGFFLLLDVGKDSWNVFHKAVEKGLSFVPAKPFFLRGGDTMARLSVSV
HHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCEEHEEEHH
ATKEEIIEGVKILNEVIRNI
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8899719; 11427726 [H]