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The map label for this gene is htpX-2 [H]

Identifier: 15899930

GI number: 15899930

Start: 2975459

End: 2976436

Strand: Direct

Name: htpX-2 [H]

Synonym: SSO3231

Alternate gene names: 15899930

Gene position: 2975459-2976436 (Clockwise)

Preceding gene: 15899923

Following gene: 15899933

Centisome position: 99.44

GC content: 35.69

Gene sequence:

>978_bases
ATGAATTGGGAAGTAGTAAAATTAAGATTAAATATGGCGTTAGCAACTCTAGGAATTACCTTACTAGGATTTGCATTGGC
GTTAGCAGTTGCGGATTATGCGTTCGGGGCGCAATTTGGAGTAGGATTAATATTATCTATCTTAATATTTATATTCTTCC
TTAACATTATTCAATGGTTGTTCGGACCATATATGATAAACTGGGCATATAGGACAGTAGAAGTAACTCCTACTGATCCA
GTTTATGGATGGTTATACAGTACTGTAGCCGAAGTTGCAAAATATAATGGATTTAGAGAAGTACCAAAAGTTTACATTGC
TGATGTGCCATTCCCTAATGCTTTTGCATATGGAAGTCCGATAGCTGGTAAAAGAATAGCCTTTACATTACCAATATTAA
AATTACTAAATAGGGATGAAATAATGGCAGTAGCGGGACATGAGCTAGGACATCTAAAGCATAGAGATGTAGAATTGCTA
ATGGCTGTAGGTCTGATTCCAGCTTTAATTTATTACTTAGGTTGGTGGTTATTCTGGGGAGGATTGTTTAGTGGAGGAGG
AAATGGTAGAGGGAATAATGGAGGATTAGTTTTCCTTTTAGGAATTATAATGATGGCAGTAAGTTTTGTTTTTCAACTAC
TAGTACTATCCTTAAATAGAATGAGAGAAGCCTACGCAGATGTTAACTCGGCCTTAACAGTACCTGGTGGAAAAGAAAAC
TTGCAACTAGCCTTAGCTAAATTAACACTATCAATGGATCCAGAAGCATTAGAAAGATTTAAGAAAAAGAGTACTACAAA
CCAAATGGCAAGTATGTTATTCTTTACCAACGCCATTGAAGAAGTTCCAACATGGAATGCCAAAGAGTTAGTGGAAATTT
GGAAAACTACAAAGGTTCCATGGTATGCTGATATATTTATGGATCATCCACATCCTGCCAAAAGGATACAGTTACTAGAT
AAAGTTTCAAAATATTAA

Upstream 100 bases:

>100_bases
TTTATATTTGTGATGCACCTTAACCCTTTATGCGAATTCAACAAATCCACGAAGCAGATGTGATGAAAAATAATATAAAC
TCCCTGCACGAGATTAGCAT

Downstream 100 bases:

>100_bases
TTATTCGAACTCTATAGTTGCAGGTGGTTTAGAAGTAACATCATAAAGTACTTCTTTAACATTAGGTATTTTTTGTAATA
TTTCAGAACTAATTTTACTT

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MNWEVVKLRLNMALATLGITLLGFALALAVADYAFGAQFGVGLILSILIFIFFLNIIQWLFGPYMINWAYRTVEVTPTDP
VYGWLYSTVAEVAKYNGFREVPKVYIADVPFPNAFAYGSPIAGKRIAFTLPILKLLNRDEIMAVAGHELGHLKHRDVELL
MAVGLIPALIYYLGWWLFWGGLFSGGGNGRGNNGGLVFLLGIIMMAVSFVFQLLVLSLNRMREAYADVNSALTVPGGKEN
LQLALAKLTLSMDPEALERFKKKSTTNQMASMLFFTNAIEEVPTWNAKELVEIWKTTKVPWYADIFMDHPHPAKRIQLLD
KVSKY

Sequences:

>Translated_325_residues
MNWEVVKLRLNMALATLGITLLGFALALAVADYAFGAQFGVGLILSILIFIFFLNIIQWLFGPYMINWAYRTVEVTPTDP
VYGWLYSTVAEVAKYNGFREVPKVYIADVPFPNAFAYGSPIAGKRIAFTLPILKLLNRDEIMAVAGHELGHLKHRDVELL
MAVGLIPALIYYLGWWLFWGGLFSGGGNGRGNNGGLVFLLGIIMMAVSFVFQLLVLSLNRMREAYADVNSALTVPGGKEN
LQLALAKLTLSMDPEALERFKKKSTTNQMASMLFFTNAIEEVPTWNAKELVEIWKTTKVPWYADIFMDHPHPAKRIQLLD
KVSKY
>Mature_325_residues
MNWEVVKLRLNMALATLGITLLGFALALAVADYAFGAQFGVGLILSILIFIFFLNIIQWLFGPYMINWAYRTVEVTPTDP
VYGWLYSTVAEVAKYNGFREVPKVYIADVPFPNAFAYGSPIAGKRIAFTLPILKLLNRDEIMAVAGHELGHLKHRDVELL
MAVGLIPALIYYLGWWLFWGGLFSGGGNGRGNNGGLVFLLGIIMMAVSFVFQLLVLSLNRMREAYADVNSALTVPGGKEN
LQLALAKLTLSMDPEALERFKKKSTTNQMASMLFFTNAIEEVPTWNAKELVEIWKTTKVPWYADIFMDHPHPAKRIQLLD
KVSKY

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=289, Percent_Identity=25.2595155709343, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 36420; Mature: 36420

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWEVVKLRLNMALATLGITLLGFALALAVADYAFGAQFGVGLILSILIFIFFLNIIQWL
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGPYMINWAYRTVEVTPTDPVYGWLYSTVAEVAKYNGFREVPKVYIADVPFPNAFAYGSP
HHHHHEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHCCHHEEECCCCCCCCCCCCC
IAGKRIAFTLPILKLLNRDEIMAVAGHELGHLKHRDVELLMAVGLIPALIYYLGWWLFWG
CCCCHHHHHHHHHHHHCCCCEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLFSGGGNGRGNNGGLVFLLGIIMMAVSFVFQLLVLSLNRMREAYADVNSALTVPGGKEN
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHH
LQLALAKLTLSMDPEALERFKKKSTTNQMASMLFFTNAIEEVPTWNAKELVEIWKTTKVP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
WYADIFMDHPHPAKRIQLLDKVSKY
EEEHHEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNWEVVKLRLNMALATLGITLLGFALALAVADYAFGAQFGVGLILSILIFIFFLNIIQWL
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGPYMINWAYRTVEVTPTDPVYGWLYSTVAEVAKYNGFREVPKVYIADVPFPNAFAYGSP
HHHHHEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHCCHHEEECCCCCCCCCCCCC
IAGKRIAFTLPILKLLNRDEIMAVAGHELGHLKHRDVELLMAVGLIPALIYYLGWWLFWG
CCCCHHHHHHHHHHHHCCCCEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLFSGGGNGRGNNGGLVFLLGIIMMAVSFVFQLLVLSLNRMREAYADVNSALTVPGGKEN
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHH
LQLALAKLTLSMDPEALERFKKKSTTNQMASMLFFTNAIEEVPTWNAKELVEIWKTTKVP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
WYADIFMDHPHPAKRIQLLDKVSKY
EEEHHEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA