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The map label for this gene is glcD [H]

Identifier: 15899867

GI number: 15899867

Start: 2911880

End: 2913283

Strand: Reverse

Name: glcD [H]

Synonym: SSO3163

Alternate gene names: 15899867

Gene position: 2913283-2911880 (Counterclockwise)

Preceding gene: 15899868

Following gene: 15899866

Centisome position: 97.36

GC content: 37.89

Gene sequence:

>1404_bases
GTGATTAGCAAATTAGCTGAAATAGTGGGCGAGGAGTGGGTAATTTCTGGAGATGAAGCTAAACTATATTCCTACCCGGC
ATTTATACCATTAAAAATAGAACCTCCAGTTGTCGTTTTACCCGGAAGTGAGGAGGAGGTAATTTCTTTAGTAAATTTTC
TGAATGAGAATAATATAAAGTATATAGTAAGGGGTTCTGGGACAAGTTTAAGTGGGGCAACCACACCAACACAAGGTGAA
GTAGTAATTTCGTTAACAAGGCTAAACAGAATTTATTCACTGGATAATTTTGAAATTACGGTAGGACCAGGATTAGCAAA
CTTTTTAATTAATAAAACATTAGGTAATTCTAACCTTTTCTACGCCCCAGATCCTTCAAGTTATGTGGTATCATCTATAG
GCGGTAATATAAGTCACGACTCAGGTGGGATGCATACTCCAAAATATGGCACTACGTTCGACAGTATAATTAGGTTAAAG
GTTCTTTTAAGTAATGGACATGTTGAGGAGATTGGTAGTAGTAATTTCTTTGATCCTACATCAATATTTGTAGGCGCAGA
GGGTACTTTAGGAGTTATCTTAAGGGCGACGCTAAGGTTATTCCCGAAACCTGAAGTTAGTAAGACTATTCTAGCCTCAT
TTAATTCTATTGACGATGCTGGGAAAGCAGTTGTAAGCGTATATAAAGCTGGAGTAACACCAGCAGCAATGGAATTTCTA
GATAAGAATTCCATAATTGCCATAGAGAACACTCAATATAAAGCAAATTATCCTATGGCTGAAGCTATTCTCCTAATAGA
ACTTGACGGGTATAGTGTTAATGTGGAAGAGGAGGAGGTCAGAGTAGTGAGTGCGATAAGGAATAATAATGGTGAAGTGT
TTATCCCTAAAGATGAGGAAGAGAAAAATAGATGGTGGTGGGGTAGAAAGGGAGCTTTTCCATCATTTGCCTATTACTCT
CCGGCTTATTTAACATTAGACGCTAATGTTCCCAGATCGACCTTACCTACAATGTTAAGATTTACGTATGAAATTAGTAA
GAAATATGGATTGCCCGTTGCTAACAGTTTCCACGCTGGAGATGGTACCCTACATCCGCTAATAGGTTTTGATCCTAAGA
ACGCTGATGAAACAATTAAAGCAATTAAAGCAGCTGAAGAGATTACAAAATTAGCTATAAAAGTAGGCGGAGTACCTAGT
GGAGAACACGGCATTGGTATAGAGAAGATAAAGTTTATGAAGCTTTACTACTCAGAAGACGACTTGACCCTAATGCGAAG
ACTAAAGGCGACATTTGATCCCAAGAGGCTTCTAAATCCGTGTAAGTTGATTCCTCCAGCTAAAAATGAAATATGCAACA
CGGTAAATAGGATACATACTTACTTATTAGAGGGAGATATATGA

Upstream 100 bases:

>100_bases
TATTCTTCAACCTGGGTTGATACTTTAATATGGAAGTTTATATATGATAAAGATAAAATATAAAAGGTAATTTATAAACT
ATTTTGAAGACGTTAACCAT

Downstream 100 bases:

>100_bases
TCTCGTCCTTAAAATTAACTGAAATGTGTACCCACTGTGGATTTTGTCTAGAAACTTGCCCAACGTACGTTGTAACTAGA
AATGAAGTGCACTCACCGAG

Product: glycolate oxidase glcD subunit. (glcD)

Products: 2-oxo acid; H2O2

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MISKLAEIVGEEWVISGDEAKLYSYPAFIPLKIEPPVVVLPGSEEEVISLVNFLNENNIKYIVRGSGTSLSGATTPTQGE
VVISLTRLNRIYSLDNFEITVGPGLANFLINKTLGNSNLFYAPDPSSYVVSSIGGNISHDSGGMHTPKYGTTFDSIIRLK
VLLSNGHVEEIGSSNFFDPTSIFVGAEGTLGVILRATLRLFPKPEVSKTILASFNSIDDAGKAVVSVYKAGVTPAAMEFL
DKNSIIAIENTQYKANYPMAEAILLIELDGYSVNVEEEEVRVVSAIRNNNGEVFIPKDEEEKNRWWWGRKGAFPSFAYYS
PAYLTLDANVPRSTLPTMLRFTYEISKKYGLPVANSFHAGDGTLHPLIGFDPKNADETIKAIKAAEEITKLAIKVGGVPS
GEHGIGIEKIKFMKLYYSEDDLTLMRRLKATFDPKRLLNPCKLIPPAKNEICNTVNRIHTYLLEGDI

Sequences:

>Translated_467_residues
MISKLAEIVGEEWVISGDEAKLYSYPAFIPLKIEPPVVVLPGSEEEVISLVNFLNENNIKYIVRGSGTSLSGATTPTQGE
VVISLTRLNRIYSLDNFEITVGPGLANFLINKTLGNSNLFYAPDPSSYVVSSIGGNISHDSGGMHTPKYGTTFDSIIRLK
VLLSNGHVEEIGSSNFFDPTSIFVGAEGTLGVILRATLRLFPKPEVSKTILASFNSIDDAGKAVVSVYKAGVTPAAMEFL
DKNSIIAIENTQYKANYPMAEAILLIELDGYSVNVEEEEVRVVSAIRNNNGEVFIPKDEEEKNRWWWGRKGAFPSFAYYS
PAYLTLDANVPRSTLPTMLRFTYEISKKYGLPVANSFHAGDGTLHPLIGFDPKNADETIKAIKAAEEITKLAIKVGGVPS
GEHGIGIEKIKFMKLYYSEDDLTLMRRLKATFDPKRLLNPCKLIPPAKNEICNTVNRIHTYLLEGDI
>Mature_467_residues
MISKLAEIVGEEWVISGDEAKLYSYPAFIPLKIEPPVVVLPGSEEEVISLVNFLNENNIKYIVRGSGTSLSGATTPTQGE
VVISLTRLNRIYSLDNFEITVGPGLANFLINKTLGNSNLFYAPDPSSYVVSSIGGNISHDSGGMHTPKYGTTFDSIIRLK
VLLSNGHVEEIGSSNFFDPTSIFVGAEGTLGVILRATLRLFPKPEVSKTILASFNSIDDAGKAVVSVYKAGVTPAAMEFL
DKNSIIAIENTQYKANYPMAEAILLIELDGYSVNVEEEEVRVVSAIRNNNGEVFIPKDEEEKNRWWWGRKGAFPSFAYYS
PAYLTLDANVPRSTLPTMLRFTYEISKKYGLPVANSFHAGDGTLHPLIGFDPKNADETIKAIKAAEEITKLAIKVGGVPS
GEHGIGIEKIKFMKLYYSEDDLTLMRRLKATFDPKRLLNPCKLIPPAKNEICNTVNRIHTYLLEGDI

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=427, Percent_Identity=31.8501170960187, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI37595754, Length=450, Percent_Identity=30.2222222222222, Blast_Score=191, Evalue=9e-49,
Organism=Homo sapiens, GI119964728, Length=436, Percent_Identity=24.0825688073394, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI4501993, Length=249, Percent_Identity=27.710843373494, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1789351, Length=460, Percent_Identity=37.8260869565217, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI48994907, Length=220, Percent_Identity=25.4545454545455, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71992373, Length=426, Percent_Identity=26.9953051643192, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71992381, Length=426, Percent_Identity=25.5868544600939, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71992392, Length=383, Percent_Identity=26.1096605744125, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17534361, Length=443, Percent_Identity=26.1851015801354, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17556096, Length=463, Percent_Identity=22.8941684665227, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320027, Length=440, Percent_Identity=29.0909090909091, Blast_Score=176, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6320023, Length=470, Percent_Identity=24.2553191489362, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320764, Length=439, Percent_Identity=25.5125284738041, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI18921117, Length=465, Percent_Identity=25.5913978494624, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24639277, Length=465, Percent_Identity=25.5913978494624, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24639275, Length=465, Percent_Identity=25.5913978494624, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24653753, Length=464, Percent_Identity=22.4137931034483, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: 1.1.3.15

Molecular weight: Translated: 51325; Mature: 51325

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISKLAEIVGEEWVISGDEAKLYSYPAFIPLKIEPPVVVLPGSEEEVISLVNFLNENNIK
CHHHHHHHCCCCEEEECCCCEEEECCCEEEEEECCCEEEECCCHHHHHHHHHHHCCCCEE
YIVRGSGTSLSGATTPTQGEVVISLTRLNRIYSLDNFEITVGPGLANFLINKTLGNSNLF
EEEEECCCCCCCCCCCCCCCEEEEEEHHHHHEECCCEEEEECCCHHHHHHHHCCCCCCEE
YAPDPSSYVVSSIGGNISHDSGGMHTPKYGTTFDSIIRLKVLLSNGHVEEIGSSNFFDPT
ECCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHEEEEEEECCCCHHHCCCCCCCCCC
SIFVGAEGTLGVILRATLRLFPKPEVSKTILASFNSIDDAGKAVVSVYKAGVTPAAMEFL
EEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHH
DKNSIIAIENTQYKANYPMAEAILLIELDGYSVNVEEEEVRVVSAIRNNNGEVFIPKDEE
CCCCEEEEECCEEECCCCHHHEEEEEEECCCEECCCHHHHHHHHHHHCCCCCEEEECCCC
EKNRWWWGRKGAFPSFAYYSPAYLTLDANVPRSTLPTMLRFTYEISKKYGLPVANSFHAG
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECC
DGTLHPLIGFDPKNADETIKAIKAAEEITKLAIKVGGVPSGEHGIGIEKIKFMKLYYSED
CCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHEEEEEEEEECCC
DLTLMRRLKATFDPKRLLNPCKLIPPAKNEICNTVNRIHTYLLEGDI
HHHHHHHHHHCCCHHHHCCCHHCCCCCHHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure
MISKLAEIVGEEWVISGDEAKLYSYPAFIPLKIEPPVVVLPGSEEEVISLVNFLNENNIK
CHHHHHHHCCCCEEEECCCCEEEECCCEEEEEECCCEEEECCCHHHHHHHHHHHCCCCEE
YIVRGSGTSLSGATTPTQGEVVISLTRLNRIYSLDNFEITVGPGLANFLINKTLGNSNLF
EEEEECCCCCCCCCCCCCCCEEEEEEHHHHHEECCCEEEEECCCHHHHHHHHCCCCCCEE
YAPDPSSYVVSSIGGNISHDSGGMHTPKYGTTFDSIIRLKVLLSNGHVEEIGSSNFFDPT
ECCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHEEEEEEECCCCHHHCCCCCCCCCC
SIFVGAEGTLGVILRATLRLFPKPEVSKTILASFNSIDDAGKAVVSVYKAGVTPAAMEFL
EEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHH
DKNSIIAIENTQYKANYPMAEAILLIELDGYSVNVEEEEVRVVSAIRNNNGEVFIPKDEE
CCCCEEEEECCEEECCCCHHHEEEEEEECCCEECCCHHHHHHHHHHHCCCCCEEEECCCC
EKNRWWWGRKGAFPSFAYYSPAYLTLDANVPRSTLPTMLRFTYEISKKYGLPVANSFHAG
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECC
DGTLHPLIGFDPKNADETIKAIKAAEEITKLAIKVGGVPSGEHGIGIEKIKFMKLYYSED
CCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHEEEEEEEEECCC
DLTLMRRLKATFDPKRLLNPCKLIPPAKNEICNTVNRIHTYLLEGDI
HHHHHHHHHHCCCHHHHCCCHHCCCCCHHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-2-hydroxy acid; O2

Specific reaction: (S)-2-hydroxy acid + O2 = 2-oxo acid + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]