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The map label for this gene is dapA-2 [H]

Identifier: 15899742

GI number: 15899742

Start: 2784953

End: 2785861

Strand: Direct

Name: dapA-2 [H]

Synonym: SSO3035

Alternate gene names: 15899742

Gene position: 2784953-2785861 (Clockwise)

Preceding gene: 15899740

Following gene: 15899744

Centisome position: 93.07

GC content: 37.84

Gene sequence:

>909_bases
ATGGATGGAGTTTTCCTAACCAACGTAACACCTTTCACCAAAACATTGGAGCTAGACTTAGAAGGGCTAAAAAGAATCGT
GGAGTTCGCACAGAACTCCGGGTATAAGTATATTGTGCCTTTAGGTACTGCTGGTGAATTCTCCTCTTTAACCGTTGAAG
AGAAAGTTAGAGTTGTTGATCATGTGAGAAGAGCATTAAGTAAGGGCGAAATTATAGCTGGTGCCTCATCTACCTCATTT
TTAGAAACTGGTGAGCTTTGCAAGAAATATAAGGAGATAGGTGTCGATAAAATTATGGTCTTACCTCCTTATTACTTAAA
GGGTAATGAAAAGGGACTGATGGAGTATTTCTTTAAGGTGGCTGAACTATGTGATTCAACCATGGTATTATATAACAATC
CATCATCAACGGGAGTGGATCTCTCTCCTCAACTAATAAAGAGATTAAATGATATGATACCTAGTTTTAGGGTGCTAAAG
GAGGCTAGGTATAATGTTGTAGAATTTAAGGAAGTGGTAAGACTAGTAGGGGATAAGATAGATGTAATAGATGGTTTAGA
AGAGAGAGCGCTATTGGGTCTTGTTTTAGGGGCTAAAGGATTTACAACTTCAATGGGCTCCTTTTCCTCTTTACCCCTTA
TGATTTATGAGAGTTATGAGAAAAAGAGGAATATTGATACTGCCATAAGACTATATGATCTGCTCTTAGAGTATAGGTCA
TTTATAAAACTCCCCTTGACAATGTCCCATTTAGCTAAGCTAGGGGCGTGGCTACGTGGTTTAATCTCAAGCTATGCTAC
ACGACCACCGCTACCAAATTTGGACGATGTGGTAAGTGAGGATGTTAAGAGAAAGATGATAGAGAAAATAAATCAAATAA
TAAGCTTTGAGAAAAATACTATAGAGTAA

Upstream 100 bases:

>100_bases
ATCTTCTAAACTTAACTCTGGATAAGCCAAACTAGTGAACACGATTTCCATTGAAATAGATTAGCAATATGTTTTATAAG
TTTTCTACGAAGATAGAGAT

Downstream 100 bases:

>100_bases
GGCAGATTGTATAATGAACTATTGCACTAATATGAAGGGACTTCCCTTAGCCCCCAACAGGTTAAGACATATGCCATCAT
TATTACAAAGGTAAAACCAT

Product: dihydrodipicolinate synthase (dapA-2)

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MDGVFLTNVTPFTKTLELDLEGLKRIVEFAQNSGYKYIVPLGTAGEFSSLTVEEKVRVVDHVRRALSKGEIIAGASSTSF
LETGELCKKYKEIGVDKIMVLPPYYLKGNEKGLMEYFFKVAELCDSTMVLYNNPSSTGVDLSPQLIKRLNDMIPSFRVLK
EARYNVVEFKEVVRLVGDKIDVIDGLEERALLGLVLGAKGFTTSMGSFSSLPLMIYESYEKKRNIDTAIRLYDLLLEYRS
FIKLPLTMSHLAKLGAWLRGLISSYATRPPLPNLDDVVSEDVKRKMIEKINQIISFEKNTIE

Sequences:

>Translated_302_residues
MDGVFLTNVTPFTKTLELDLEGLKRIVEFAQNSGYKYIVPLGTAGEFSSLTVEEKVRVVDHVRRALSKGEIIAGASSTSF
LETGELCKKYKEIGVDKIMVLPPYYLKGNEKGLMEYFFKVAELCDSTMVLYNNPSSTGVDLSPQLIKRLNDMIPSFRVLK
EARYNVVEFKEVVRLVGDKIDVIDGLEERALLGLVLGAKGFTTSMGSFSSLPLMIYESYEKKRNIDTAIRLYDLLLEYRS
FIKLPLTMSHLAKLGAWLRGLISSYATRPPLPNLDDVVSEDVKRKMIEKINQIISFEKNTIE
>Mature_302_residues
MDGVFLTNVTPFTKTLELDLEGLKRIVEFAQNSGYKYIVPLGTAGEFSSLTVEEKVRVVDHVRRALSKGEIIAGASSTSF
LETGELCKKYKEIGVDKIMVLPPYYLKGNEKGLMEYFFKVAELCDSTMVLYNNPSSTGVDLSPQLIKRLNDMIPSFRVLK
EARYNVVEFKEVVRLVGDKIDVIDGLEERALLGLVLGAKGFTTSMGSFSSLPLMIYESYEKKRNIDTAIRLYDLLLEYRS
FIKLPLTMSHLAKLGAWLRGLISSYATRPPLPNLDDVVSEDVKRKMIEKINQIISFEKNTIE

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=260, Percent_Identity=25.7692307692308, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI13540533, Length=213, Percent_Identity=29.1079812206573, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1786463, Length=274, Percent_Identity=27.7372262773723, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788823, Length=200, Percent_Identity=30.5, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI87082415, Length=271, Percent_Identity=26.1992619926199, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1789620, Length=212, Percent_Identity=26.4150943396226, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 34047; Mature: 34047

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGVFLTNVTPFTKTLELDLEGLKRIVEFAQNSGYKYIVPLGTAGEFSSLTVEEKVRVVD
CCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHH
HVRRALSKGEIIAGASSTSFLETGELCKKYKEIGVDKIMVLPPYYLKGNEKGLMEYFFKV
HHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHCCCCCCHHHHHHHHH
AELCDSTMVLYNNPSSTGVDLSPQLIKRLNDMIPSFRVLKEARYNVVEFKEVVRLVGDKI
HHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHCCHH
DVIDGLEERALLGLVLGAKGFTTSMGSFSSLPLMIYESYEKKRNIDTAIRLYDLLLEYRS
HHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FIKLPLTMSHLAKLGAWLRGLISSYATRPPLPNLDDVVSEDVKRKMIEKINQIISFEKNT
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHC
IE
CC
>Mature Secondary Structure
MDGVFLTNVTPFTKTLELDLEGLKRIVEFAQNSGYKYIVPLGTAGEFSSLTVEEKVRVVD
CCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHH
HVRRALSKGEIIAGASSTSFLETGELCKKYKEIGVDKIMVLPPYYLKGNEKGLMEYFFKV
HHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHCCCCCCHHHHHHHHH
AELCDSTMVLYNNPSSTGVDLSPQLIKRLNDMIPSFRVLKEARYNVVEFKEVVRLVGDKI
HHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHCCHH
DVIDGLEERALLGLVLGAKGFTTSMGSFSSLPLMIYESYEKKRNIDTAIRLYDLLLEYRS
HHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FIKLPLTMSHLAKLGAWLRGLISSYATRPPLPNLDDVVSEDVKRKMIEKINQIISFEKNT
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHC
IE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA