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The map label for this gene is cutA-6 [H]

Identifier: 15899651

GI number: 15899651

Start: 2687185

End: 2689239

Strand: Direct

Name: cutA-6 [H]

Synonym: SSO2942

Alternate gene names: 15899651

Gene position: 2687185-2689239 (Clockwise)

Preceding gene: 15899649

Following gene: 15899652

Centisome position: 89.8

GC content: 40.19

Gene sequence:

>2055_bases
ATGATAAGAGAAGATCTTCCGAAAATAACTGGAAAAGGAACGTACATTGATGATATTGACCCTAGGAACACGGTTTATCT
AGGCATAATTAGGTCACCCATAGCTAGAGGTATTATAAAGAGCATATCAAGACCAGAAAAAGCTCTGCTTACTCTAACGT
GGGAAGACGTTAAGATTTACATGCCAGTAAGAGTAGATCCAGAGACACTAAAGCAATCTAACATAGTGAAAATGCCTATT
CTAGCTGATGGTAAAGTAAATTTCGTTGGACAACCAGTCTTAGCTTATGTCGTAGAGGACAGATACGCGATTGAGGACAT
TGCGGACGAGATGTCAATAGAGTACGAGGAACTTAAGCCAATTATTGACGTGGAAAAAGCTATGAACAGTGACGATGAGA
TACATTCCGGGGCTAAAAGAAATATCTCAGTGAATAAACTACTAGAAGGGGGAGAGCTATCTGCTAAGAAAAGAGCAGAA
GTTGTAGTAAGCAGGAAGATAAATCAAGCTAGAATAATTTCAAATCCTATGGAGCCTAAGGGGATTATAGCACATTGGGA
TGGAGAGTATTTAAATATATATGGCTCTTTTCAATCCTCTTTTAGAATAAAGAACGATTTAAGGGAGACCTTAAACCTAT
CCCCGGAGAAAATTAGGGTGTATTCTCCCCAAAACGTTGGAGGGGGATTTGGAAATAAGGTACCAGCTCACCCCGAGTAT
GTGATAGCTTCTATTGCGTCAATGAAATTAGGTAGACCAGTAAAATGGATAGAGACTAGATATGAGCACTTAAAAAATCC
CACAGTTGGGAGAGGAGTTCTATCTGATGTGAAAATGTATGCCACTAAGCAAGGTGAAATACTAGGAATAGAGGGTTATG
TGGCTGTAGATTTAGGCGCATATAATTACACATTAAATCCTACAACCCCAGCATTCATAGCTCAACTGCTTACTGGACCT
TATAAAATGAGGTTTGCGTCAATCAGAGCCTATGGAATATTCACAAACTTGCCTCCCACTGGCCCTTATAGGGGTGCTGG
TAGACCAGAGGCTGCTTTAATTCATGAGACTTTGGTTGAGGATTTGGCTGAGGAGTTGGGTGTGGATTCTGTTGAGATTA
GGAGGAGGAATTTGATTAGTGATAATGGTTACGTTACTCCTTTGGGTGTTAGGATTGATCCTGCTGGTTATAATGAGGTG
TTGAATGAGGCTGAGAAGTATTATAGGAAGGCTAAGGAGGTTTATAAGGACAAGGGAGTTTCAATAGTGGTATTTACAGA
TATTATAAGGCTATCTCCAGGGGAAGGAGCGAGAGTAAGAATAGAGAACGGGAAAATTAAGATCTTTGTGGGAACAGGAC
CTCATGGTCAAGCTCATGGTGATACGTTTTCGAAGCTAGCTTCAGAGACATTGGGAATTCCTCAAGATTTAATCGAAGTA
GTTGCCAACACAACTGATGGAGTAAAAGAAGGAATAGGGAGTTTCGGTTCTAGAAGTGCAACTGTAGGAGGTTCAGCAGT
TATCGAAGCTTGTAGGCAGTTATTAAGCAAAGTTAATATGCCTATAGATAAAGCGCTGAAGGAGATGAATGGTATGGAGG
CGGAAATATTCTATAAATCAGATGATATATTTTCACCTGGTTCTCATGTTGCAGTTGTTGACGTAGATAGAGATACTGGA
TTCGTTAAGGTTCTTGAGTACTATGCCGTAGATGACGTGGGCAGAATCCTAATAAAGGAAGAAGTAGAAGGTCAAATTAT
TGGTGGAGTATTACAAGGTGTTTCGCAAGTATTATGGGAACATGCACCCTATGATGAAAATGGAAATCCGCTATTCTCGT
CAATTGCAGACTGTGGAGTTCCGACTGCTGTTGAAGCGAGTTATAAGGTTTATGTTAGTGAGGTTGAATATCCATCTGCA
ACTTCAGCTAAAAGCAGAGGAGTAGGAGAAGCGGGAACAACTGGTGGATTACCTGCCGTATTCTTGGCCCTAGAGAAAAT
TACACATAGAAAGTTTAATAAAACTCCAATATATCCTTGGGATATTACAAGATAG

Upstream 100 bases:

>100_bases
AGTCTAATTCTAGTAGAGGTAGATATGTGTTTAATCAAACTAGTTTTATCGCACTAGTTTTAGGAAAAACTATTAAGCAG
TAAACCATAATTTTCTACCA

Downstream 100 bases:

>100_bases
CGAAATGTTGATTTTTTGTCTTATTAAATTTTATATTTTCGGATCAAGGATTAGACTACTTCCCTATTGAGAGTTGGTTT
CCTTAAAAATACCTATGTTA

Product: carbon monoxide dehydrogenase, large chain (cutA-6)

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 684; Mature: 684

Protein sequence:

>684_residues
MIREDLPKITGKGTYIDDIDPRNTVYLGIIRSPIARGIIKSISRPEKALLTLTWEDVKIYMPVRVDPETLKQSNIVKMPI
LADGKVNFVGQPVLAYVVEDRYAIEDIADEMSIEYEELKPIIDVEKAMNSDDEIHSGAKRNISVNKLLEGGELSAKKRAE
VVVSRKINQARIISNPMEPKGIIAHWDGEYLNIYGSFQSSFRIKNDLRETLNLSPEKIRVYSPQNVGGGFGNKVPAHPEY
VIASIASMKLGRPVKWIETRYEHLKNPTVGRGVLSDVKMYATKQGEILGIEGYVAVDLGAYNYTLNPTTPAFIAQLLTGP
YKMRFASIRAYGIFTNLPPTGPYRGAGRPEAALIHETLVEDLAEELGVDSVEIRRRNLISDNGYVTPLGVRIDPAGYNEV
LNEAEKYYRKAKEVYKDKGVSIVVFTDIIRLSPGEGARVRIENGKIKIFVGTGPHGQAHGDTFSKLASETLGIPQDLIEV
VANTTDGVKEGIGSFGSRSATVGGSAVIEACRQLLSKVNMPIDKALKEMNGMEAEIFYKSDDIFSPGSHVAVVDVDRDTG
FVKVLEYYAVDDVGRILIKEEVEGQIIGGVLQGVSQVLWEHAPYDENGNPLFSSIADCGVPTAVEASYKVYVSEVEYPSA
TSAKSRGVGEAGTTGGLPAVFLALEKITHRKFNKTPIYPWDITR

Sequences:

>Translated_684_residues
MIREDLPKITGKGTYIDDIDPRNTVYLGIIRSPIARGIIKSISRPEKALLTLTWEDVKIYMPVRVDPETLKQSNIVKMPI
LADGKVNFVGQPVLAYVVEDRYAIEDIADEMSIEYEELKPIIDVEKAMNSDDEIHSGAKRNISVNKLLEGGELSAKKRAE
VVVSRKINQARIISNPMEPKGIIAHWDGEYLNIYGSFQSSFRIKNDLRETLNLSPEKIRVYSPQNVGGGFGNKVPAHPEY
VIASIASMKLGRPVKWIETRYEHLKNPTVGRGVLSDVKMYATKQGEILGIEGYVAVDLGAYNYTLNPTTPAFIAQLLTGP
YKMRFASIRAYGIFTNLPPTGPYRGAGRPEAALIHETLVEDLAEELGVDSVEIRRRNLISDNGYVTPLGVRIDPAGYNEV
LNEAEKYYRKAKEVYKDKGVSIVVFTDIIRLSPGEGARVRIENGKIKIFVGTGPHGQAHGDTFSKLASETLGIPQDLIEV
VANTTDGVKEGIGSFGSRSATVGGSAVIEACRQLLSKVNMPIDKALKEMNGMEAEIFYKSDDIFSPGSHVAVVDVDRDTG
FVKVLEYYAVDDVGRILIKEEVEGQIIGGVLQGVSQVLWEHAPYDENGNPLFSSIADCGVPTAVEASYKVYVSEVEYPSA
TSAKSRGVGEAGTTGGLPAVFLALEKITHRKFNKTPIYPWDITR
>Mature_684_residues
MIREDLPKITGKGTYIDDIDPRNTVYLGIIRSPIARGIIKSISRPEKALLTLTWEDVKIYMPVRVDPETLKQSNIVKMPI
LADGKVNFVGQPVLAYVVEDRYAIEDIADEMSIEYEELKPIIDVEKAMNSDDEIHSGAKRNISVNKLLEGGELSAKKRAE
VVVSRKINQARIISNPMEPKGIIAHWDGEYLNIYGSFQSSFRIKNDLRETLNLSPEKIRVYSPQNVGGGFGNKVPAHPEY
VIASIASMKLGRPVKWIETRYEHLKNPTVGRGVLSDVKMYATKQGEILGIEGYVAVDLGAYNYTLNPTTPAFIAQLLTGP
YKMRFASIRAYGIFTNLPPTGPYRGAGRPEAALIHETLVEDLAEELGVDSVEIRRRNLISDNGYVTPLGVRIDPAGYNEV
LNEAEKYYRKAKEVYKDKGVSIVVFTDIIRLSPGEGARVRIENGKIKIFVGTGPHGQAHGDTFSKLASETLGIPQDLIEV
VANTTDGVKEGIGSFGSRSATVGGSAVIEACRQLLSKVNMPIDKALKEMNGMEAEIFYKSDDIFSPGSHVAVVDVDRDTG
FVKVLEYYAVDDVGRILIKEEVEGQIIGGVLQGVSQVLWEHAPYDENGNPLFSSIADCGVPTAVEASYKVYVSEVEYPSA
TSAKSRGVGEAGTTGGLPAVFLALEKITHRKFNKTPIYPWDITR

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=728, Percent_Identity=24.0384615384615, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1789230, Length=664, Percent_Identity=26.6566265060241, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1789246, Length=776, Percent_Identity=22.9381443298969, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1786478, Length=561, Percent_Identity=24.0641711229947, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17540638, Length=725, Percent_Identity=22.6206896551724, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17539860, Length=698, Percent_Identity=24.3553008595989, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24647193, Length=550, Percent_Identity=22.7272727272727, Blast_Score=83, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24647199, Length=523, Percent_Identity=22.5621414913958, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24647195, Length=653, Percent_Identity=21.4395099540582, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 75216; Mature: 75216

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIREDLPKITGKGTYIDDIDPRNTVYLGIIRSPIARGIIKSISRPEKALLTLTWEDVKIY
CCCCCCCCCCCCCCEECCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCEEEEEEEECEEEE
MPVRVDPETLKQSNIVKMPILADGKVNFVGQPVLAYVVEDRYAIEDIADEMSIEYEELKP
EEEEECHHHHCCCCEEEEEEEECCCEEECCCHHHHHHHHCCHHHHHHHHHHCCCHHHHCH
IIDVEKAMNSDDEIHSGAKRNISVNKLLEGGELSAKKRAEVVVSRKINQARIISNPMEPK
HHHHHHHCCCCHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCC
GIIAHWDGEYLNIYGSFQSSFRIKNDLRETLNLSPEKIRVYSPQNVGGGFGNKVPAHPEY
CEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHH
VIASIASMKLGRPVKWIETRYEHLKNPTVGRGVLSDVKMYATKQGEILGIEGYVAVDLGA
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEECCEEEEEECC
YNYTLNPTTPAFIAQLLTGPYKMRFASIRAYGIFTNLPPTGPYRGAGRPEAALIHETLVE
EEEEECCCCHHHHHHHHCCCHHEEEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
DLAEELGVDSVEIRRRNLISDNGYVTPLGVRIDPAGYNEVLNEAEKYYRKAKEVYKDKGV
HHHHHHCCCHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
SIVVFTDIIRLSPGEGARVRIENGKIKIFVGTGPHGQAHGDTFSKLASETLGIPQDLIEV
EEEEEEEEEEECCCCCCEEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHH
VANTTDGVKEGIGSFGSRSATVGGSAVIEACRQLLSKVNMPIDKALKEMNGMEAEIFYKS
HHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECC
DDIFSPGSHVAVVDVDRDTGFVKVLEYYAVDDVGRILIKEEVEGQIIGGVLQGVSQVLWE
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
HAPYDENGNPLFSSIADCGVPTAVEASYKVYVSEVEYPSATSAKSRGVGEAGTTGGLPAV
CCCCCCCCCHHHHHHHHCCCCCEECCCEEEEEEECCCCCCCCHHHCCCCCCCCCCCHHHH
FLALEKITHRKFNKTPIYPWDITR
HHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MIREDLPKITGKGTYIDDIDPRNTVYLGIIRSPIARGIIKSISRPEKALLTLTWEDVKIY
CCCCCCCCCCCCCCEECCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCEEEEEEEECEEEE
MPVRVDPETLKQSNIVKMPILADGKVNFVGQPVLAYVVEDRYAIEDIADEMSIEYEELKP
EEEEECHHHHCCCCEEEEEEEECCCEEECCCHHHHHHHHCCHHHHHHHHHHCCCHHHHCH
IIDVEKAMNSDDEIHSGAKRNISVNKLLEGGELSAKKRAEVVVSRKINQARIISNPMEPK
HHHHHHHCCCCHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCC
GIIAHWDGEYLNIYGSFQSSFRIKNDLRETLNLSPEKIRVYSPQNVGGGFGNKVPAHPEY
CEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHH
VIASIASMKLGRPVKWIETRYEHLKNPTVGRGVLSDVKMYATKQGEILGIEGYVAVDLGA
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEECCEEEEEECC
YNYTLNPTTPAFIAQLLTGPYKMRFASIRAYGIFTNLPPTGPYRGAGRPEAALIHETLVE
EEEEECCCCHHHHHHHHCCCHHEEEEEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
DLAEELGVDSVEIRRRNLISDNGYVTPLGVRIDPAGYNEVLNEAEKYYRKAKEVYKDKGV
HHHHHHCCCHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
SIVVFTDIIRLSPGEGARVRIENGKIKIFVGTGPHGQAHGDTFSKLASETLGIPQDLIEV
EEEEEEEEEEECCCCCCEEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHH
VANTTDGVKEGIGSFGSRSATVGGSAVIEACRQLLSKVNMPIDKALKEMNGMEAEIFYKS
HHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECC
DDIFSPGSHVAVVDVDRDTGFVKVLEYYAVDDVGRILIKEEVEGQIIGGVLQGVSQVLWE
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
HAPYDENGNPLFSSIADCGVPTAVEASYKVYVSEVEYPSATSAKSRGVGEAGTTGGLPAV
CCCCCCCCCHHHHHHHHCCCCCEECCCEEEEEEECCCCCCCCHHHCCCCCCCCCCCHHHH
FLALEKITHRKFNKTPIYPWDITR
HHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]