Click here to switch to the map view.

The map label for this gene is hyuA-3

Identifier: 15899645

GI number: 15899645

Start: 2678727

End: 2680679

Strand: Reverse

Name: hyuA-3

Synonym: SSO2936

Alternate gene names: NA

Gene position: 2680679-2678727 (Counterclockwise)

Preceding gene: 15899646

Following gene: 15899644

Centisome position: 89.59

GC content: 40.4

Gene sequence:

>1953_bases
TTGATGAATATGGAGTGTAAAGTGGCAATAGATATAGGCGGGACGTTCACTGATTTCATAGTCCTAGCCAGCGATGGGGA
AATTAAGACAATAAAAATCCTAACTAACCCTAAGGACCCTGGACAAGTCATTAAGGATGTAATAAGCACTTTAAACTGCA
ACGTAAGTGAGATAGCTCACGCCACGACCCTAGCGACGAATACGTTGTTAGGGCAGGAGAACTTAACAATTCCAAAAACA
GCCTTACTCGTTACGAAGGGATTTAGGGATATTATCGAAATAGGTAGGCAGAATAGGCCTAGACTTTATGATTTATATTT
TGAAAAGCCAAGACAGCTGGTACTTAGAAGTTTGAGATTTGAGATTGACGAGAGGATCAACGCTGAAGGAAATATGATAA
AGGAGGTAGATCAAGATGAGATAGAGAGGGTTGCTAAAAAGCTTTTAGACGAAAATGTAATATCAATTGCTGTAAGTTAT
CTGCACTCTTACTTGAATCCAAAAAATGAACTAATTACTGAAAACGTGTTAAAGAAGTATTTCAAATACATCTCAATCTC
CTCAAAAATAGCACCAGAACCTAGAGAATACGAAAGGACTTCCACTGCAGTAGTTAACGCAGTGCTAATGCCAATAGTAT
CTGCGTACCTTGAGAGGTTACAAGTCTCTTTACCAACCGAGAACTTCTACATTATGTCAAGTTCTGGAGGATTGGTAGAT
ATTAAAGAAGCATCTGAGAAGCCGGTACAGTTAATTGAATCCGGGCCAGCAGCTGGTGTAATAGCTTCAGCTAGCTTTTT
GCCTAATGAGAGTTTAATAAGCTTCGATATGGGAGGTACCACCGCTAAGGCAGGTGTTATAATTAATGGTAATTTTGAAA
TGACCACTGAGTATGAAGTTGGAGGAGAAGTACATTACGGAAGGATAGTTAAGGGTAGTGGGTATCCAGTAAGGTTCCCA
TTTGTTGATTTAGCAGAGGTGTCTGCTGGTGGAGGTACAATAATATGGAGGGACGAGGCTAATGCCTTAAAAGTCGGGCC
TATAAGTGCCGGTGCAGATCCCGGGCCGATTTCCTACGGAAAGGGAGGAAATAGGCCTACCATAGCTGATGCAAACTTGA
TTTTAGGAAGATTGGGGACAGAGCTTATTGGTGGTAATCTAAAGTTAGATAAAGAGAGCGCAATAAGGGGGATGAGTAAG
TTGGGTGATCCATATGAGGTAAGTAAGAACGCCTTAGGATTGGTAAATCTGGAGATGGCTAGGGCAATAAGATTAGTCAC
GGTGGAGAGGGGATTAGATCCATCGAACTTCTCCTTAATAGCCTTTGGAGGTGCTGGTCCACAACACGCAGTATACTTGG
CTGAGGAGGTAGGAATAGGTAAGGTTATAATACCACCTCATCCAGGCTTATTCAGTGCATTAGGACTATTACTTGCTGAT
TGGCGTTTTGAAGTTAGGAAATCATATCCTAAAGACTTAGGGAGTGAATTTGAACAATTGGAAAAGGAGCTATACGAGAA
GTTAAAGGGAAACGTCGATTACTTCTTGAGACTTGCAGATGTGAGGTATGAGGGGCAAGGATGGGAGTTAACAATTCCGG
TAAATAACGTTAATGAGATTAGGAAAGTATTTGAGGAGAAACACCTAGCCACTTATGGTTTCGTGATGAAAGATAGGGAG
ATAGAGGTTGTTACAATAAGAGTTTTCGCTATCAAGAAGAGACCACTACCTAAAATAAAGGTAGCTTTTGGAAATTATGA
TAAGCCAAGAGAAGTTAGAAAGGTAGTAATTGACGACGATTGGGTAAATGTAGATGTCTATGTTAGGGAGAAGTTGCCTA
AAGGTTTTAGAATAGGGGGGCCAGCAATAATTGAGGAATATAGTTCGACTACAGTTATAAAGGATGGTTGGAATGCAATT
ATAGATGATTCAATAGTATTGGTGAGAGAATGA

Upstream 100 bases:

>100_bases
CCAAAACACCTCGTACACCTAATTGCAAACTAATAAGAGCTAGATTAATAAACGGGGAAGTAGTTTTTGAGGATAAACCA
TTTGTACCCAGAACAAAGGG

Downstream 100 bases:

>100_bases
CAAGTTGGGAAATAATTTACAAAGCCTCTGAGTTCATTGCAGAGGAAATGGGCGTCATGCTAAAGAGGTCAGCTATGTCA
CCGAATATTAGGGAGAGGAT

Product: N-methylhydantoinase A (hyuA-3)

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 650; Mature: 650

Protein sequence:

>650_residues
MMNMECKVAIDIGGTFTDFIVLASDGEIKTIKILTNPKDPGQVIKDVISTLNCNVSEIAHATTLATNTLLGQENLTIPKT
ALLVTKGFRDIIEIGRQNRPRLYDLYFEKPRQLVLRSLRFEIDERINAEGNMIKEVDQDEIERVAKKLLDENVISIAVSY
LHSYLNPKNELITENVLKKYFKYISISSKIAPEPREYERTSTAVVNAVLMPIVSAYLERLQVSLPTENFYIMSSSGGLVD
IKEASEKPVQLIESGPAAGVIASASFLPNESLISFDMGGTTAKAGVIINGNFEMTTEYEVGGEVHYGRIVKGSGYPVRFP
FVDLAEVSAGGGTIIWRDEANALKVGPISAGADPGPISYGKGGNRPTIADANLILGRLGTELIGGNLKLDKESAIRGMSK
LGDPYEVSKNALGLVNLEMARAIRLVTVERGLDPSNFSLIAFGGAGPQHAVYLAEEVGIGKVIIPPHPGLFSALGLLLAD
WRFEVRKSYPKDLGSEFEQLEKELYEKLKGNVDYFLRLADVRYEGQGWELTIPVNNVNEIRKVFEEKHLATYGFVMKDRE
IEVVTIRVFAIKKRPLPKIKVAFGNYDKPREVRKVVIDDDWVNVDVYVREKLPKGFRIGGPAIIEEYSSTTVIKDGWNAI
IDDSIVLVRE

Sequences:

>Translated_650_residues
MMNMECKVAIDIGGTFTDFIVLASDGEIKTIKILTNPKDPGQVIKDVISTLNCNVSEIAHATTLATNTLLGQENLTIPKT
ALLVTKGFRDIIEIGRQNRPRLYDLYFEKPRQLVLRSLRFEIDERINAEGNMIKEVDQDEIERVAKKLLDENVISIAVSY
LHSYLNPKNELITENVLKKYFKYISISSKIAPEPREYERTSTAVVNAVLMPIVSAYLERLQVSLPTENFYIMSSSGGLVD
IKEASEKPVQLIESGPAAGVIASASFLPNESLISFDMGGTTAKAGVIINGNFEMTTEYEVGGEVHYGRIVKGSGYPVRFP
FVDLAEVSAGGGTIIWRDEANALKVGPISAGADPGPISYGKGGNRPTIADANLILGRLGTELIGGNLKLDKESAIRGMSK
LGDPYEVSKNALGLVNLEMARAIRLVTVERGLDPSNFSLIAFGGAGPQHAVYLAEEVGIGKVIIPPHPGLFSALGLLLAD
WRFEVRKSYPKDLGSEFEQLEKELYEKLKGNVDYFLRLADVRYEGQGWELTIPVNNVNEIRKVFEEKHLATYGFVMKDRE
IEVVTIRVFAIKKRPLPKIKVAFGNYDKPREVRKVVIDDDWVNVDVYVREKLPKGFRIGGPAIIEEYSSTTVIKDGWNAI
IDDSIVLVRE
>Mature_650_residues
MMNMECKVAIDIGGTFTDFIVLASDGEIKTIKILTNPKDPGQVIKDVISTLNCNVSEIAHATTLATNTLLGQENLTIPKT
ALLVTKGFRDIIEIGRQNRPRLYDLYFEKPRQLVLRSLRFEIDERINAEGNMIKEVDQDEIERVAKKLLDENVISIAVSY
LHSYLNPKNELITENVLKKYFKYISISSKIAPEPREYERTSTAVVNAVLMPIVSAYLERLQVSLPTENFYIMSSSGGLVD
IKEASEKPVQLIESGPAAGVIASASFLPNESLISFDMGGTTAKAGVIINGNFEMTTEYEVGGEVHYGRIVKGSGYPVRFP
FVDLAEVSAGGGTIIWRDEANALKVGPISAGADPGPISYGKGGNRPTIADANLILGRLGTELIGGNLKLDKESAIRGMSK
LGDPYEVSKNALGLVNLEMARAIRLVTVERGLDPSNFSLIAFGGAGPQHAVYLAEEVGIGKVIIPPHPGLFSALGLLLAD
WRFEVRKSYPKDLGSEFEQLEKELYEKLKGNVDYFLRLADVRYEGQGWELTIPVNNVNEIRKVFEEKHLATYGFVMKDRE
IEVVTIRVFAIKKRPLPKIKVAFGNYDKPREVRKVVIDDDWVNVDVYVREKLPKGFRIGGPAIIEEYSSTTVIKDGWNAI
IDDSIVLVRE

Specific function: Unknown

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=727, Percent_Identity=29.1609353507565, Blast_Score=204, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI133901900, Length=702, Percent_Identity=27.7777777777778, Blast_Score=204, Evalue=8e-53,
Organism=Saccharomyces cerevisiae, GI6322634, Length=759, Percent_Identity=29.6442687747036, Blast_Score=240, Evalue=4e-64,
Organism=Drosophila melanogaster, GI45550492, Length=724, Percent_Identity=29.5580110497238, Blast_Score=234, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: 3.5.2.14

Molecular weight: Translated: 71887; Mature: 71887

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNMECKVAIDIGGTFTDFIVLASDGEIKTIKILTNPKDPGQVIKDVISTLNCNVSEIAH
CCCCEEEEEEEECCCEEEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHH
ATTLATNTLLGQENLTIPKTALLVTKGFRDIIEIGRQNRPRLYDLYFEKPRQLVLRSLRF
HHHHHHHHEECCCCCCCCHHHEEEHHHHHHHHHHCCCCCCEEEEHHHHCHHHHHHHHHHH
EIDERINAEGNMIKEVDQDEIERVAKKLLDENVISIAVSYLHSYLNPKNELITENVLKKY
HHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FKYISISSKIAPEPREYERTSTAVVNAVLMPIVSAYLERLQVSLPTENFYIMSSSGGLVD
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCEEE
IKEASEKPVQLIESGPAAGVIASASFLPNESLISFDMGGTTAKAGVIINGNFEMTTEYEV
ECCCCCCCHHHHHCCCCCCEEEECCCCCCCCEEEEECCCCCEECCEEEECCEEEEEEEEC
GGEVHYGRIVKGSGYPVRFPFVDLAEVSAGGGTIIWRDEANALKVGPISAGADPGPISYG
CCEEEEEEEEECCCCEEECCCCCHHHCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCC
KGGNRPTIADANLILGRLGTELIGGNLKLDKESAIRGMSKLGDPYEVSKNALGLVNLEMA
CCCCCCCEECHHHHHHHHHHHHHCCCEEECHHHHHHHHHHCCCCHHHCCCCCEEEEHHHH
RAIRLVTVERGLDPSNFSLIAFGGAGPQHAVYLAEEVGIGKVIIPPHPGLFSALGLLLAD
HHEEEEEEECCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHH
WRFEVRKSYPKDLGSEFEQLEKELYEKLKGNVDYFLRLADVRYEGQGWELTIPVNNVNEI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCEEEEEECCCHHHH
RKVFEEKHLATYGFVMKDREIEVVTIRVFAIKKRPLPKIKVAFGNYDKPREVRKVVIDDD
HHHHHHHHHHHEEEEEECCCEEEEEEEEEEEECCCCCEEEEEECCCCCCHHHHEEEECCC
WVNVDVYVREKLPKGFRIGGPAIIEEYSSTTVIKDGWNAIIDDSIVLVRE
EEEEEEEEEECCCCCCCCCCHHHHHHCCCCEEEECCCCEEECCCEEEEEC
>Mature Secondary Structure
MMNMECKVAIDIGGTFTDFIVLASDGEIKTIKILTNPKDPGQVIKDVISTLNCNVSEIAH
CCCCEEEEEEEECCCEEEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHH
ATTLATNTLLGQENLTIPKTALLVTKGFRDIIEIGRQNRPRLYDLYFEKPRQLVLRSLRF
HHHHHHHHEECCCCCCCCHHHEEEHHHHHHHHHHCCCCCCEEEEHHHHCHHHHHHHHHHH
EIDERINAEGNMIKEVDQDEIERVAKKLLDENVISIAVSYLHSYLNPKNELITENVLKKY
HHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FKYISISSKIAPEPREYERTSTAVVNAVLMPIVSAYLERLQVSLPTENFYIMSSSGGLVD
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCEEE
IKEASEKPVQLIESGPAAGVIASASFLPNESLISFDMGGTTAKAGVIINGNFEMTTEYEV
ECCCCCCCHHHHHCCCCCCEEEECCCCCCCCEEEEECCCCCEECCEEEECCEEEEEEEEC
GGEVHYGRIVKGSGYPVRFPFVDLAEVSAGGGTIIWRDEANALKVGPISAGADPGPISYG
CCEEEEEEEEECCCCEEECCCCCHHHCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCC
KGGNRPTIADANLILGRLGTELIGGNLKLDKESAIRGMSKLGDPYEVSKNALGLVNLEMA
CCCCCCCEECHHHHHHHHHHHHHCCCEEECHHHHHHHHHHCCCCHHHCCCCCEEEEHHHH
RAIRLVTVERGLDPSNFSLIAFGGAGPQHAVYLAEEVGIGKVIIPPHPGLFSALGLLLAD
HHEEEEEEECCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHH
WRFEVRKSYPKDLGSEFEQLEKELYEKLKGNVDYFLRLADVRYEGQGWELTIPVNNVNEI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCEEEEEECCCHHHH
RKVFEEKHLATYGFVMKDREIEVVTIRVFAIKKRPLPKIKVAFGNYDKPREVRKVVIDDD
HHHHHHHHHHHEEEEEECCCEEEEEEEEEEEECCCCCEEEEEECCCCCCHHHHEEEECCC
WVNVDVYVREKLPKGFRIGGPAIIEEYSSTTVIKDGWNAIIDDSIVLVRE
EEEEEEEEEECCCCCCCCCCHHHHHHCCCCEEEECCCCEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]