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The map label for this gene is livM [H]

Identifier: 15899554

GI number: 15899554

Start: 2600826

End: 2601863

Strand: Direct

Name: livM [H]

Synonym: SSO2841

Alternate gene names: 15899554

Gene position: 2600826-2601863 (Clockwise)

Preceding gene: 15899553

Following gene: 15899555

Centisome position: 86.92

GC content: 37.28

Gene sequence:

>1038_bases
ATGGTAGTAGATATTTCCTCCCTCATTTTAGCCATACTCCTAGACTTTTCAGTATATTTAATGGTAGTAATATCGTTAAA
TGTAGAAATAGGATTAACTGGAGTTCCAAATTTCGGTAGAGTCCTAGCATATGCTGGAGGAGCCTTCATAGCTGGAGCAG
TACCTGGGAGGATTTTGCAAATAATATATGGACTTCACGGTGATTATATTCTTAATAATCCCTCTATAATAGCAGAAATA
AACGATAAATTGCTTGAACAACCATTAATGGCTCTCGCCATTTTAATTCTTACCTTAGCTCTAGCTGGGATAGTCGGAGC
AACCTTAGGTTATATTTCCTCCTATCCAGCCTTAAGATTAAGAGAAGATTATCTGGGAATATTACTATTAGTAGCTGGGA
CTTCACTAGTAGTAGTAGGGATTACTTATCCACCAATAGTAGGAGGTACAGTAGGCGTTCAAGTTCCCGCTGTTTTTAAT
GCACTTCTAGGTCAAGGAGCTAGTTTATATTACAAGATATCAATATTGTTGCTAGTATTCTCACTAATTATGCTACTTCT
ATTCAATTTAATATCAAACTCTCCAATGGGAAGAGCATTTAGAGCTGTTAGAGAAAATGAGGATTTAGTAGAAGTTTTAG
GTAGAGATATAGGTGTAATCAGAGGTAAGGCAATGGCGTTGGGAGGATTTCTTGCCGGTGTAGCAGGATCACTTTACGCT
TTTTACATAGGTTCAGTATTTGCAGGTGCATTCGATAATTTAACGTGGTCATTTAACCCGTATTTAATGCTAATATTGGG
AGGCGCAGGGACTTCAATAGGTGCATTGCTAGGTGCCCTGATATATTCCACCTTATATCACGTTATCGATTTGTATAAGC
AGACAATAGGATATTATCTGCATTTCGATGCAGTATGGCTACAGTATATGCTATTTGGACTTGTACTAACAATAATCCTT
ATATTACGACCTCAAGGTATCGTAGTTGAAAAAGCCAAACCATTAGTAAAACCGAAAGCTAAGGACCAGAAAACCTAA

Upstream 100 bases:

>100_bases
CTTTCGTTATTAACCAGTATTCAACACTGGTTCCTCTTATAGTAGTAGCAGCAGTTCTCCTGATAGCTCCAAACGGAATT
ATGGGAGTGAGGGTGAAATA

Downstream 100 bases:

>100_bases
CTAGTTAAAGAAATTTTTCTTGTTATAAGTTATCTGATACCACTAATAAAATGCGGAGCTGAATTTCTATAAAGTAGAAC
ATCCGAGGACAACCAAACTA

Product: ABC transporter, permease (branched chain amino acid)

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MVVDISSLILAILLDFSVYLMVVISLNVEIGLTGVPNFGRVLAYAGGAFIAGAVPGRILQIIYGLHGDYILNNPSIIAEI
NDKLLEQPLMALAILILTLALAGIVGATLGYISSYPALRLREDYLGILLLVAGTSLVVVGITYPPIVGGTVGVQVPAVFN
ALLGQGASLYYKISILLLVFSLIMLLLFNLISNSPMGRAFRAVRENEDLVEVLGRDIGVIRGKAMALGGFLAGVAGSLYA
FYIGSVFAGAFDNLTWSFNPYLMLILGGAGTSIGALLGALIYSTLYHVIDLYKQTIGYYLHFDAVWLQYMLFGLVLTIIL
ILRPQGIVVEKAKPLVKPKAKDQKT

Sequences:

>Translated_345_residues
MVVDISSLILAILLDFSVYLMVVISLNVEIGLTGVPNFGRVLAYAGGAFIAGAVPGRILQIIYGLHGDYILNNPSIIAEI
NDKLLEQPLMALAILILTLALAGIVGATLGYISSYPALRLREDYLGILLLVAGTSLVVVGITYPPIVGGTVGVQVPAVFN
ALLGQGASLYYKISILLLVFSLIMLLLFNLISNSPMGRAFRAVRENEDLVEVLGRDIGVIRGKAMALGGFLAGVAGSLYA
FYIGSVFAGAFDNLTWSFNPYLMLILGGAGTSIGALLGALIYSTLYHVIDLYKQTIGYYLHFDAVWLQYMLFGLVLTIIL
ILRPQGIVVEKAKPLVKPKAKDQKT
>Mature_345_residues
MVVDISSLILAILLDFSVYLMVVISLNVEIGLTGVPNFGRVLAYAGGAFIAGAVPGRILQIIYGLHGDYILNNPSIIAEI
NDKLLEQPLMALAILILTLALAGIVGATLGYISSYPALRLREDYLGILLLVAGTSLVVVGITYPPIVGGTVGVQVPAVFN
ALLGQGASLYYKISILLLVFSLIMLLLFNLISNSPMGRAFRAVRENEDLVEVLGRDIGVIRGKAMALGGFLAGVAGSLYA
FYIGSVFAGAFDNLTWSFNPYLMLILGGAGTSIGALLGALIYSTLYHVIDLYKQTIGYYLHFDAVWLQYMLFGLVLTIIL
ILRPQGIVVEKAKPLVKPKAKDQKT

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=364, Percent_Identity=23.9010989010989, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 36957; Mature: 36957

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVDISSLILAILLDFSVYLMVVISLNVEIGLTGVPNFGRVLAYAGGAFIAGAVPGRILQ
CEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCHHEECCCHHHHHH
IIYGLHGDYILNNPSIIAEINDKLLEQPLMALAILILTLALAGIVGATLGYISSYPALRL
HHHHCCCCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
REDYLGILLLVAGTSLVVVGITYPPIVGGTVGVQVPAVFNALLGQGASLYYKISILLLVF
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHH
SLIMLLLFNLISNSPMGRAFRAVRENEDLVEVLGRDIGVIRGKAMALGGFLAGVAGSLYA
HHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHH
FYIGSVFAGAFDNLTWSFNPYLMLILGGAGTSIGALLGALIYSTLYHVIDLYKQTIGYYL
HHHHHHHHHHHCCCEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HFDAVWLQYMLFGLVLTIILILRPQGIVVEKAKPLVKPKAKDQKT
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MVVDISSLILAILLDFSVYLMVVISLNVEIGLTGVPNFGRVLAYAGGAFIAGAVPGRILQ
CEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCHHEECCCHHHHHH
IIYGLHGDYILNNPSIIAEINDKLLEQPLMALAILILTLALAGIVGATLGYISSYPALRL
HHHHCCCCEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
REDYLGILLLVAGTSLVVVGITYPPIVGGTVGVQVPAVFNALLGQGASLYYKISILLLVF
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHH
SLIMLLLFNLISNSPMGRAFRAVRENEDLVEVLGRDIGVIRGKAMALGGFLAGVAGSLYA
HHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHH
FYIGSVFAGAFDNLTWSFNPYLMLILGGAGTSIGALLGALIYSTLYHVIDLYKQTIGYYL
HHHHHHHHHHHCCCEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HFDAVWLQYMLFGLVLTIILILRPQGIVVEKAKPLVKPKAKDQKT
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]