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The map label for this gene is livK [C]

Identifier: 15899550

GI number: 15899550

Start: 2597333

End: 2598418

Strand: Direct

Name: livK [C]

Synonym: SSO2835

Alternate gene names: 15899550

Gene position: 2597333-2598418 (Clockwise)

Preceding gene: 15899549

Following gene: 15899551

Centisome position: 86.8

GC content: 38.12

Gene sequence:

>1086_bases
ATGCAAGTGCAAGTAGTAATAGAGGATACAGCAACTAATCCACAGACTGCTCTTTCCGATTTGCAGACTTTATACTCCCA
AGGAGTTAAGCTAGTAATTGGGCCATTTTCAAGTGGTGAATTGAGGCAAATAATGTCTTATGCTGAAAGTAATGGCATAA
TGCTCTTCTCCCCATCATCAACTTCTCCTGCGTTAGCAACACCCGATAGGATTAACGGAACTATATTTAGAGATGTGCCT
AATGATACCTATCAAGGGGCTGTAATAGCAAACATAATGTATCAGCAAGGTATTAGGGCAATAGCAGTAATATGGAGAGG
AGATACTTATGGTGATGGATTAGTAAGCGTAGTAAATAAGACATTTACTGCGTTAGGTGGAAAGGTAATGCTTGTGGCTA
GATATGATCCTTCTACCACAGATTTTTCCAGCTATGTAAGTACTCTAGCAAATACTATTAGTCAGTTAATTAACCAGTAT
GGTAAAGATCACGTAGCTGTTTATGACGTTTCTTTTGAGGAAGGAGCTAGTATACTTCAATTGGCCAGTCAATATCCCCA
ATTAACGGAGGTTAAATGGTACGGTTCAGATGGTACTGCTGGTGTTGGATCAATAGTACAGAATCCAGTAGCTGCACAAG
TTGCAGTTGAAACACTATTCCTAAATCCTATTGCAGCACCTGCCCATACAGTATTCTATGATCAATTAACCCAACACTTC
AATAAAACCCTTCAAGCTTATTCCTATATAACATATGACATATTCTGGATATACTTTTACAGTGTATTAAAAGTGGGAAG
TGATAATGTAACTGCTATTAAATCAATTTTACCAAAAGTAGCTGCTAAGTTCTATGGTGCATCAGGATATCACTTGTTTG
ACAAATATGGTGATAGAGTTTCTGGTATTTATCAATTGCAGATAGTAAATAAGACAGCCTCCGGTTACGAATGGACTATC
TATGGTGTCTATGATGTTACCACGCATACATTAACCATAGGATTCCCTCCAGCTGCTCAACCCCCACAAGGCTATCTTTA
TCCAGATGATCCCCAAGCTATGTCTAAGTTAAGTAGTATAAGTTAA

Upstream 100 bases:

>100_bases
TAATAATTTTATTGTTTTTCTCTATATCAATCTCTTTTTGAAAGTGCTAATATTATATCTTTCAAATGAAATAATTTGGT
GAAACACCACTGGTGTAAAT

Downstream 100 bases:

>100_bases
TATTAAAGGGGTGTTGTTTTTTGTCTCTTCTTAAATTGGATTCCGTTTCTAAGTATTTCGGTGGTATTAAGGCATTAGAT
AGTGTAACATTAGAGATTGA

Product: ABC transporter, binding protein (branched chain amino acid)

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MQVQVVIEDTATNPQTALSDLQTLYSQGVKLVIGPFSSGELRQIMSYAESNGIMLFSPSSTSPALATPDRINGTIFRDVP
NDTYQGAVIANIMYQQGIRAIAVIWRGDTYGDGLVSVVNKTFTALGGKVMLVARYDPSTTDFSSYVSTLANTISQLINQY
GKDHVAVYDVSFEEGASILQLASQYPQLTEVKWYGSDGTAGVGSIVQNPVAAQVAVETLFLNPIAAPAHTVFYDQLTQHF
NKTLQAYSYITYDIFWIYFYSVLKVGSDNVTAIKSILPKVAAKFYGASGYHLFDKYGDRVSGIYQLQIVNKTASGYEWTI
YGVYDVTTHTLTIGFPPAAQPPQGYLYPDDPQAMSKLSSIS

Sequences:

>Translated_361_residues
MQVQVVIEDTATNPQTALSDLQTLYSQGVKLVIGPFSSGELRQIMSYAESNGIMLFSPSSTSPALATPDRINGTIFRDVP
NDTYQGAVIANIMYQQGIRAIAVIWRGDTYGDGLVSVVNKTFTALGGKVMLVARYDPSTTDFSSYVSTLANTISQLINQY
GKDHVAVYDVSFEEGASILQLASQYPQLTEVKWYGSDGTAGVGSIVQNPVAAQVAVETLFLNPIAAPAHTVFYDQLTQHF
NKTLQAYSYITYDIFWIYFYSVLKVGSDNVTAIKSILPKVAAKFYGASGYHLFDKYGDRVSGIYQLQIVNKTASGYEWTI
YGVYDVTTHTLTIGFPPAAQPPQGYLYPDDPQAMSKLSSIS
>Mature_361_residues
MQVQVVIEDTATNPQTALSDLQTLYSQGVKLVIGPFSSGELRQIMSYAESNGIMLFSPSSTSPALATPDRINGTIFRDVP
NDTYQGAVIANIMYQQGIRAIAVIWRGDTYGDGLVSVVNKTFTALGGKVMLVARYDPSTTDFSSYVSTLANTISQLINQY
GKDHVAVYDVSFEEGASILQLASQYPQLTEVKWYGSDGTAGVGSIVQNPVAAQVAVETLFLNPIAAPAHTVFYDQLTQHF
NKTLQAYSYITYDIFWIYFYSVLKVGSDNVTAIKSILPKVAAKFYGASGYHLFDKYGDRVSGIYQLQIVNKTASGYEWTI
YGVYDVTTHTLTIGFPPAAQPPQGYLYPDDPQAMSKLSSIS

Specific function: This Protein Is A Component Of The Leucine-Specific Transport System, Which Is One Of The Two Periplasmic Binding Protein-Dependent Transport Systems Of The High-Affinity Transport Of The Branched-Chain Amino Acids In E.Coli. [C]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 39459; Mature: 39459

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVQVVIEDTATNPQTALSDLQTLYSQGVKLVIGPFSSGELRQIMSYAESNGIMLFSPSS
CEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCEEEECCCC
TSPALATPDRINGTIFRDVPNDTYQGAVIANIMYQQGIRAIAVIWRGDTYGDGLVSVVNK
CCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHH
TFTALGGKVMLVARYDPSTTDFSSYVSTLANTISQLINQYGKDHVAVYDVSFEEGASILQ
HHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCHHHHH
LASQYPQLTEVKWYGSDGTAGVGSIVQNPVAAQVAVETLFLNPIAAPAHTVFYDQLTQHF
HHHHCCCEEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
NKTLQAYSYITYDIFWIYFYSVLKVGSDNVTAIKSILPKVAAKFYGASGYHLFDKYGDRV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHH
SGIYQLQIVNKTASGYEWTIYGVYDVTTHTLTIGFPPAAQPPQGYLYPDDPQAMSKLSSI
CCEEEEEEEECCCCCCEEEEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCC
S
C
>Mature Secondary Structure
MQVQVVIEDTATNPQTALSDLQTLYSQGVKLVIGPFSSGELRQIMSYAESNGIMLFSPSS
CEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCEEEECCCC
TSPALATPDRINGTIFRDVPNDTYQGAVIANIMYQQGIRAIAVIWRGDTYGDGLVSVVNK
CCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHH
TFTALGGKVMLVARYDPSTTDFSSYVSTLANTISQLINQYGKDHVAVYDVSFEEGASILQ
HHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCHHHHH
LASQYPQLTEVKWYGSDGTAGVGSIVQNPVAAQVAVETLFLNPIAAPAHTVFYDQLTQHF
HHHHCCCEEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
NKTLQAYSYITYDIFWIYFYSVLKVGSDNVTAIKSILPKVAAKFYGASGYHLFDKYGDRV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHH
SGIYQLQIVNKTASGYEWTIYGVYDVTTHTLTIGFPPAAQPPQGYLYPDDPQAMSKLSSI
CCEEEEEEEECCCCCCEEEEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]