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The map label for this gene is adh-12 [H]

Identifier: 15899518

GI number: 15899518

Start: 2560839

End: 2561834

Strand: Reverse

Name: adh-12 [H]

Synonym: SSO2800

Alternate gene names: 15899518

Gene position: 2561834-2560839 (Counterclockwise)

Preceding gene: 15899524

Following gene: 15899514

Centisome position: 85.62

GC content: 37.65

Gene sequence:

>996_bases
GTGATGAAAGCTCTCACATTCGATAAGAACGGAATAGAAAACCTAAAGTTTACAGACTATAAGAACCCGGAAATAGGCAA
CCATGAAGTATTAATAAGAGTAAAACTAGCTGGAGTAAATCCAGTTGACTATTATACTGTTGAAAGATTGAAAGTGAACC
CAATACCACATATTCCCGGAGTTGAATTTAGTGGAGAGGTAGTAAAAGTTGGAGATCATGTTAAGAGTGTAAGTGTTGGA
GATAGAGTTACGATTTATGGTAGGATATTTGACGGAACTTGTGACATGTGTATGGCTGGATATGAAACAGTTTGTAGAAA
TGGTGGAAGAATAGGAGTTGACGCTAATGGTGGATGGGCTGAATATGTTGCAGTTGAGGAGAAGTATGTGTTTAAGCTAC
CAAATGAGTATACATGGGAGATGGGATCAAGCTTGACTGTAGCTGCTTTAACAGCGTATCACGCATTAAAAGAAGCACAA
TTGAGTCCATCACAAACACTAGTTGTATTTGGAGCATCCGGAAATACTGGAATGTTTTTGGTACAATTAGGTAAAAAGTT
TGGGGCAAAAGTAATAGCTGTATCAAGAAAGAGTTGGTTAAGGGGATATGGAGCCGATTTTGTAGTTGACTATAATGAGG
TAGAGGAAAAGGTGAAGGAAATTACAAATGGTAAGATGGCTGACGTAGTTATCAATTCCTTAGGAGAACAATTCTGGGAT
AAGAGCTTTTCAGTTTTAGGGGTCAGGGGTAAGTTAGTCACCTTTGGAACATTGTTAGGTGGTAACGTGAAGGTTGATTT
AAGTCAATTGTACAGTAAGCATATTAGCATTCTGGGCGTTAATAGGGGTAATAGGAAGGACTTTATAGAGTTACTAGACA
TATGTAAGGATTGTAAAGTAAAGACGTGGAAAATATTTAAGTTAGAAGAGGGTAAAGAGGCTTTGAAAGAGCTATTCTCT
AAAGAGAGGGATGGCAGAATTTTTCTATATCCTTGA

Upstream 100 bases:

>100_bases
AAATCTTACGAGATGCGTTTAATATATTTTTTCTTCTAACTTTGCTTATTATCTTTACCAATCTAAAGTTAACTTATTAA
CCTTTAAGCCCAAGTTAAAG

Downstream 100 bases:

>100_bases
CACCTTGCCAACTAGGAAAGATGGAAATCCTTGTTTTTCTGCCTCTTGAAGGGCATCTTCTACTTCTCTTTTTTCACCTA
TTACAAGTACTAACAACTCT

Product: zinc-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MMKALTFDKNGIENLKFTDYKNPEIGNHEVLIRVKLAGVNPVDYYTVERLKVNPIPHIPGVEFSGEVVKVGDHVKSVSVG
DRVTIYGRIFDGTCDMCMAGYETVCRNGGRIGVDANGGWAEYVAVEEKYVFKLPNEYTWEMGSSLTVAALTAYHALKEAQ
LSPSQTLVVFGASGNTGMFLVQLGKKFGAKVIAVSRKSWLRGYGADFVVDYNEVEEKVKEITNGKMADVVINSLGEQFWD
KSFSVLGVRGKLVTFGTLLGGNVKVDLSQLYSKHISILGVNRGNRKDFIELLDICKDCKVKTWKIFKLEEGKEALKELFS
KERDGRIFLYP

Sequences:

>Translated_331_residues
MMKALTFDKNGIENLKFTDYKNPEIGNHEVLIRVKLAGVNPVDYYTVERLKVNPIPHIPGVEFSGEVVKVGDHVKSVSVG
DRVTIYGRIFDGTCDMCMAGYETVCRNGGRIGVDANGGWAEYVAVEEKYVFKLPNEYTWEMGSSLTVAALTAYHALKEAQ
LSPSQTLVVFGASGNTGMFLVQLGKKFGAKVIAVSRKSWLRGYGADFVVDYNEVEEKVKEITNGKMADVVINSLGEQFWD
KSFSVLGVRGKLVTFGTLLGGNVKVDLSQLYSKHISILGVNRGNRKDFIELLDICKDCKVKTWKIFKLEEGKEALKELFS
KERDGRIFLYP
>Mature_331_residues
MMKALTFDKNGIENLKFTDYKNPEIGNHEVLIRVKLAGVNPVDYYTVERLKVNPIPHIPGVEFSGEVVKVGDHVKSVSVG
DRVTIYGRIFDGTCDMCMAGYETVCRNGGRIGVDANGGWAEYVAVEEKYVFKLPNEYTWEMGSSLTVAALTAYHALKEAQ
LSPSQTLVVFGASGNTGMFLVQLGKKFGAKVIAVSRKSWLRGYGADFVVDYNEVEEKVKEITNGKMADVVINSLGEQFWD
KSFSVLGVRGKLVTFGTLLGGNVKVDLSQLYSKHISILGVNRGNRKDFIELLDICKDCKVKTWKIFKLEEGKEALKELFS
KERDGRIFLYP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=295, Percent_Identity=28.135593220339, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI13236495, Length=295, Percent_Identity=28.135593220339, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI18379349, Length=340, Percent_Identity=25, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI194239676, Length=262, Percent_Identity=28.6259541984733, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI22538446, Length=292, Percent_Identity=26.027397260274, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI22538444, Length=292, Percent_Identity=26.027397260274, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI28557745, Length=264, Percent_Identity=28.4090909090909, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790485, Length=358, Percent_Identity=27.0949720670391, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790045, Length=198, Percent_Identity=29.2929292929293, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788073, Length=330, Percent_Identity=26.3636363636364, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081918, Length=306, Percent_Identity=25.8169934640523, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788407, Length=267, Percent_Identity=26.2172284644195, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87082125, Length=234, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787863, Length=190, Percent_Identity=31.5789473684211, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI226510992, Length=309, Percent_Identity=22.3300970873786, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786825, Length=270, Percent_Identity=27.037037037037, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788075, Length=245, Percent_Identity=29.3877551020408, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI87082401, Length=336, Percent_Identity=24.1071428571429, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71988145, Length=331, Percent_Identity=26.5861027190332, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17562584, Length=338, Percent_Identity=26.3313609467456, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17562582, Length=338, Percent_Identity=25.4437869822485, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17562876, Length=324, Percent_Identity=23.1481481481481, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17507255, Length=317, Percent_Identity=27.1293375394322, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17562878, Length=324, Percent_Identity=24.0740740740741, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6319621, Length=328, Percent_Identity=28.0487804878049, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6323961, Length=340, Percent_Identity=27.0588235294118, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324486, Length=326, Percent_Identity=26.6871165644172, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323729, Length=327, Percent_Identity=26.9113149847095, Blast_Score=93, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6319520, Length=340, Percent_Identity=24.4117647058824, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6319949, Length=352, Percent_Identity=25, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319258, Length=225, Percent_Identity=28.4444444444444, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323099, Length=321, Percent_Identity=26.4797507788162, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319257, Length=231, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323980, Length=330, Percent_Identity=24.5454545454545, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324195, Length=267, Percent_Identity=25.8426966292135, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319955, Length=327, Percent_Identity=25.3822629969419, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322619, Length=327, Percent_Identity=25.3822629969419, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17137530, Length=300, Percent_Identity=25, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17737897, Length=337, Percent_Identity=24.6290801186944, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36852; Mature: 36852

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKALTFDKNGIENLKFTDYKNPEIGNHEVLIRVKLAGVNPVDYYTVERLKVNPIPHIPG
CCCEEECCCCCCCCCEECCCCCCCCCCEEEEEEEEEECCCCCCEEEEEEEEECCCCCCCC
VEFSGEVVKVGDHVKSVSVGDRVTIYGRIFDGTCDMCMAGYETVCRNGGRIGVDANGGWA
CCCCCCEEEECCCEEEECCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCEE
EYVAVEEKYVFKLPNEYTWEMGSSLTVAALTAYHALKEAQLSPSQTLVVFGASGNTGMFL
EEEEEECEEEEECCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEE
VQLGKKFGAKVIAVSRKSWLRGYGADFVVDYNEVEEKVKEITNGKMADVVINSLGEQFWD
EEECHHHCCEEEEEEHHHHHHCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
KSFSVLGVRGKLVTFGTLLGGNVKVDLSQLYSKHISILGVNRGNRKDFIELLDICKDCKV
CCCEEEEECCEEEEEEEEECCCEEEEHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHCCC
KTWKIFKLEEGKEALKELFSKERDGRIFLYP
CEEEEEEECCHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MMKALTFDKNGIENLKFTDYKNPEIGNHEVLIRVKLAGVNPVDYYTVERLKVNPIPHIPG
CCCEEECCCCCCCCCEECCCCCCCCCCEEEEEEEEEECCCCCCEEEEEEEEECCCCCCCC
VEFSGEVVKVGDHVKSVSVGDRVTIYGRIFDGTCDMCMAGYETVCRNGGRIGVDANGGWA
CCCCCCEEEECCCEEEECCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCEE
EYVAVEEKYVFKLPNEYTWEMGSSLTVAALTAYHALKEAQLSPSQTLVVFGASGNTGMFL
EEEEEECEEEEECCCCEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEE
VQLGKKFGAKVIAVSRKSWLRGYGADFVVDYNEVEEKVKEITNGKMADVVINSLGEQFWD
EEECHHHCCEEEEEEHHHHHHCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
KSFSVLGVRGKLVTFGTLLGGNVKVDLSQLYSKHISILGVNRGNRKDFIELLDICKDCKV
CCCEEEEECCEEEEEEEEECCCEEEEHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHCCC
KTWKIFKLEEGKEALKELFSKERDGRIFLYP
CEEEEEEECCHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA