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The map label for this gene is apeH-3 [H]

Identifier: 15899413

GI number: 15899413

Start: 2447805

End: 2449580

Strand: Reverse

Name: apeH-3 [H]

Synonym: SSO2693

Alternate gene names: 15899413

Gene position: 2449580-2447805 (Counterclockwise)

Preceding gene: 15899416

Following gene: 15899409

Centisome position: 81.86

GC content: 36.54

Gene sequence:

>1776_bases
ATGAAACCAGAAGACTACTACTATTCGATTAAATTAGTACCAGAAATAACAATAGAGAATGGAAAACTATTTCACGTAGA
GACATGGATAGAAGAGGATAAATACAAATCATCAATTTATTTGAACCTCAAGAGGATAACTTTTCAAGGAAATGAATCAT
CACCTAAGTTCAATAATGATAAGCTTTACTTTATAAGAAACGAAGAGGCTAAATCATCCTTACTTGAAGCACAACTCTAT
GGCGAGCCTAAAGTAATATTTACATTTTCTGGCAAAATATCCAAATATGAGTTCCATAATAAGGGAATATTAGTGATAGC
AGAGGAAAACACAGATAAGACATTACCTTTTAGAGCCGAGAAGATAAAGTATAGGTTTGATAGCAGAGGTTTATTGAGAG
CTAGGCAATCACTTTACCTATTTGATGGTAAGGATCTGAGAAGGCTCGTTACAGGGAACTTTGACGTTACAGATTTAGCT
ACAAACGGTAATAGGGTCGTAATTTCAGCAACTAAGGACGGAGATGATTATGGATTAGGAAATTTGTATGAGGTAAATAT
AGAAACTGGGGAGTTAAACAGAATAACGAAGGAGGATGGGACTGTACAAGCAATAGCTATGAATAGCGAGGGGAAAATAG
CGTTTTTAGGGCATAGGAAAGGGCTAACCCCATGGGCTTCTCTCGAAATAATGCTACCAGAAGAAGGAAAGAGTTACATG
TGTGGAAAGACTTGCGGAAATAAAGTGTTAACTGATTTATTTGATGGCGTAAAGGATAGGATCGTATTCGAAAAAGATCT
AATACTCTCCTTAGGTCAAGAGGGAGGTACGTCACATATTTATCAAATCTCTGATAATAAGGTAGATAAGGTAACTAGTG
GAAATATAATGGTAAGAGGATTTGATTATAGTAATAGTGAACTAGCTTACTTCTATTCCACTCCAGAAAAGCCTGTAATA
TTAAAATATAGAGATATAGAATATGATCCGAACCCTAACATCAAAGGATACACTCCAGAGAGAATAACAGTAAACTCTAA
CGGAGTAGAAGTGGAGGGATGGAGTATAATTAAAGATCCTAACGCACCAACAATATTATTCATCCATGGGGGACCGCATA
TGGCGTATGGTTATGGTTATTTCATAGAATTCCAGTTCTTCGTAGATAATGGGTTTAACGTAATATATGCAAATCCTAGA
GGCAGTCAAGGATATGGGGAGGAATTCGCCAAGGCTTGTGTGGGGGATTGGGGTGGAAAGGATTTCGAAGATCTAATGAA
CTTCGTGAATACCGTTAAGGAAAGGTATAGTTTAAAAGGTAAATTCGGTATTACTGGTGGTTCTTATGGAGGCTTTATGA
CCAATTGGATAGTAACGAAGACTAGTATGTTTTCGGCTGCAATTAGCGAAAGGAGTATATCGAATCTAGTTAGTATGTGT
GGTACTAGTGATATAGGTTTTTGGTTTAATGCGATTGAATCCGGGATTGCAGATCCATGGAGTACTGAAGGCATTGAGAA
ACTAATGAAAATGTCGCCAATTTATTATGTGAAAAACGTTAAAACACCTACCATGTTAATTCACGGAGAGGAAGATTATA
GATGCCCAATTGAACAAGCTGAACAATTTTATGTTGCATTGAAGATGCAAGGAGTCCCTACAACGTTGGTAAGATACCAA
GGTGATAGTCATGAACACGCTAGAAGAGGGAAGCCTAAGAATATGATAGATAGATTGAAGACTAAATTAGAATGGTTTAG
TAAATATTTACTCTAA

Upstream 100 bases:

>100_bases
ACCAATACGTGGTTATAGAGTGCACACATATTACTCGCTCTAAAAGTTTATAAAACGATAAGATAATCAAAGTTATTACT
TAGAGCAATATACTAATATT

Downstream 100 bases:

>100_bases
TCAATATCTCTTTCACATTCCTTATTTATGGCTGAAAGAACATCTCTCAAGGTAACTACACCTATTATTTTCCCGTTTTC
ATTAATTGCTAATAAGTGAG

Product: acylaminoacyl-peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 591; Mature: 591

Protein sequence:

>591_residues
MKPEDYYYSIKLVPEITIENGKLFHVETWIEEDKYKSSIYLNLKRITFQGNESSPKFNNDKLYFIRNEEAKSSLLEAQLY
GEPKVIFTFSGKISKYEFHNKGILVIAEENTDKTLPFRAEKIKYRFDSRGLLRARQSLYLFDGKDLRRLVTGNFDVTDLA
TNGNRVVISATKDGDDYGLGNLYEVNIETGELNRITKEDGTVQAIAMNSEGKIAFLGHRKGLTPWASLEIMLPEEGKSYM
CGKTCGNKVLTDLFDGVKDRIVFEKDLILSLGQEGGTSHIYQISDNKVDKVTSGNIMVRGFDYSNSELAYFYSTPEKPVI
LKYRDIEYDPNPNIKGYTPERITVNSNGVEVEGWSIIKDPNAPTILFIHGGPHMAYGYGYFIEFQFFVDNGFNVIYANPR
GSQGYGEEFAKACVGDWGGKDFEDLMNFVNTVKERYSLKGKFGITGGSYGGFMTNWIVTKTSMFSAAISERSISNLVSMC
GTSDIGFWFNAIESGIADPWSTEGIEKLMKMSPIYYVKNVKTPTMLIHGEEDYRCPIEQAEQFYVALKMQGVPTTLVRYQ
GDSHEHARRGKPKNMIDRLKTKLEWFSKYLL

Sequences:

>Translated_591_residues
MKPEDYYYSIKLVPEITIENGKLFHVETWIEEDKYKSSIYLNLKRITFQGNESSPKFNNDKLYFIRNEEAKSSLLEAQLY
GEPKVIFTFSGKISKYEFHNKGILVIAEENTDKTLPFRAEKIKYRFDSRGLLRARQSLYLFDGKDLRRLVTGNFDVTDLA
TNGNRVVISATKDGDDYGLGNLYEVNIETGELNRITKEDGTVQAIAMNSEGKIAFLGHRKGLTPWASLEIMLPEEGKSYM
CGKTCGNKVLTDLFDGVKDRIVFEKDLILSLGQEGGTSHIYQISDNKVDKVTSGNIMVRGFDYSNSELAYFYSTPEKPVI
LKYRDIEYDPNPNIKGYTPERITVNSNGVEVEGWSIIKDPNAPTILFIHGGPHMAYGYGYFIEFQFFVDNGFNVIYANPR
GSQGYGEEFAKACVGDWGGKDFEDLMNFVNTVKERYSLKGKFGITGGSYGGFMTNWIVTKTSMFSAAISERSISNLVSMC
GTSDIGFWFNAIESGIADPWSTEGIEKLMKMSPIYYVKNVKTPTMLIHGEEDYRCPIEQAEQFYVALKMQGVPTTLVRYQ
GDSHEHARRGKPKNMIDRLKTKLEWFSKYLL
>Mature_591_residues
MKPEDYYYSIKLVPEITIENGKLFHVETWIEEDKYKSSIYLNLKRITFQGNESSPKFNNDKLYFIRNEEAKSSLLEAQLY
GEPKVIFTFSGKISKYEFHNKGILVIAEENTDKTLPFRAEKIKYRFDSRGLLRARQSLYLFDGKDLRRLVTGNFDVTDLA
TNGNRVVISATKDGDDYGLGNLYEVNIETGELNRITKEDGTVQAIAMNSEGKIAFLGHRKGLTPWASLEIMLPEEGKSYM
CGKTCGNKVLTDLFDGVKDRIVFEKDLILSLGQEGGTSHIYQISDNKVDKVTSGNIMVRGFDYSNSELAYFYSTPEKPVI
LKYRDIEYDPNPNIKGYTPERITVNSNGVEVEGWSIIKDPNAPTILFIHGGPHMAYGYGYFIEFQFFVDNGFNVIYANPR
GSQGYGEEFAKACVGDWGGKDFEDLMNFVNTVKERYSLKGKFGITGGSYGGFMTNWIVTKTSMFSAAISERSISNLVSMC
GTSDIGFWFNAIESGIADPWSTEGIEKLMKMSPIYYVKNVKTPTMLIHGEEDYRCPIEQAEQFYVALKMQGVPTTLVRYQ
GDSHEHARRGKPKNMIDRLKTKLEWFSKYLL

Specific function: Unknown

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=259, Percent_Identity=29.3436293436293, Blast_Score=119, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI25149159, Length=238, Percent_Identity=29.4117647058824, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI25144537, Length=219, Percent_Identity=29.6803652968037, Blast_Score=102, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI25144540, Length=219, Percent_Identity=29.6803652968037, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17552908, Length=229, Percent_Identity=27.9475982532751, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 67148; Mature: 67148

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPEDYYYSIKLVPEITIENGKLFHVETWIEEDKYKSSIYLNLKRITFQGNESSPKFNND
CCCCCEEEEEEEEEEEEECCCEEEEEEECCCCCCCCCEEEEEEEEEEEECCCCCCCCCCC
KLYFIRNEEAKSSLLEAQLYGEPKVIFTFSGKISKYEFHNKGILVIAEENTDKTLPFRAE
EEEEEECCHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCCEEEEEECCCCCCCCEEHE
KIKYRFDSRGLLRARQSLYLFDGKDLRRLVTGNFDVTDLATNGNRVVISATKDGDDYGLG
EEEEEECCCCHHHHCCEEEEECCHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCCCCC
NLYEVNIETGELNRITKEDGTVQAIAMNSEGKIAFLGHRKGLTPWASLEIMLPEEGKSYM
CEEEEEEECCCCCEEECCCCCEEEEEECCCCCEEEEECCCCCCCCEEEEEEECCCCCCEE
CGKTCGNKVLTDLFDGVKDRIVFEKDLILSLGQEGGTSHIYQISDNKVDKVTSGNIMVRG
CCHHHHHHHHHHHHHCHHHHEEEEEHHHHCCCCCCCCCEEEEECCCCEEEEECCCEEEEE
FDYSNSELAYFYSTPEKPVILKYRDIEYDPNPNIKGYTPERITVNSNGVEVEGWSIIKDP
ECCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCEEEECEEEEECC
NAPTILFIHGGPHMAYGYGYFIEFQFFVDNGFNVIYANPRGSQGYGEEFAKACVGDWGGK
CCCEEEEEECCCCEEEEEEEEEEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCCC
DFEDLMNFVNTVKERYSLKGKFGITGGSYGGFMTNWIVTKTSMFSAAISERSISNLVSMC
CHHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHH
GTSDIGFWFNAIESGIADPWSTEGIEKLMKMSPIYYVKNVKTPTMLIHGEEDYRCPIEQA
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCHHHC
EQFYVALKMQGVPTTLVRYQGDSHEHARRGKPKNMIDRLKTKLEWFSKYLL
CEEEEEEEECCCCEEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPEDYYYSIKLVPEITIENGKLFHVETWIEEDKYKSSIYLNLKRITFQGNESSPKFNND
CCCCCEEEEEEEEEEEEECCCEEEEEEECCCCCCCCCEEEEEEEEEEEECCCCCCCCCCC
KLYFIRNEEAKSSLLEAQLYGEPKVIFTFSGKISKYEFHNKGILVIAEENTDKTLPFRAE
EEEEEECCHHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCCEEEEEECCCCCCCCEEHE
KIKYRFDSRGLLRARQSLYLFDGKDLRRLVTGNFDVTDLATNGNRVVISATKDGDDYGLG
EEEEEECCCCHHHHCCEEEEECCHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCCCCC
NLYEVNIETGELNRITKEDGTVQAIAMNSEGKIAFLGHRKGLTPWASLEIMLPEEGKSYM
CEEEEEEECCCCCEEECCCCCEEEEEECCCCCEEEEECCCCCCCCEEEEEEECCCCCCEE
CGKTCGNKVLTDLFDGVKDRIVFEKDLILSLGQEGGTSHIYQISDNKVDKVTSGNIMVRG
CCHHHHHHHHHHHHHCHHHHEEEEEHHHHCCCCCCCCCEEEEECCCCEEEEECCCEEEEE
FDYSNSELAYFYSTPEKPVILKYRDIEYDPNPNIKGYTPERITVNSNGVEVEGWSIIKDP
ECCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCEEEECCCCEEEECEEEEECC
NAPTILFIHGGPHMAYGYGYFIEFQFFVDNGFNVIYANPRGSQGYGEEFAKACVGDWGGK
CCCEEEEEECCCCEEEEEEEEEEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCCC
DFEDLMNFVNTVKERYSLKGKFGITGGSYGGFMTNWIVTKTSMFSAAISERSISNLVSMC
CHHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHH
GTSDIGFWFNAIESGIADPWSTEGIEKLMKMSPIYYVKNVKTPTMLIHGEEDYRCPIEQA
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCHHHC
EQFYVALKMQGVPTTLVRYQGDSHEHARRGKPKNMIDRLKTKLEWFSKYLL
CEEEEEEEECCCCEEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]