BacMap

Definition	Sulfolobus solfataricus P2 chromosome, complete genome.
Accession	NC_002754
Length	2,992,245

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The map label for this gene is fabG-8 [H]

Identifier: 15899387

GI number: 15899387

Start: 2420871

End: 2421629

Strand: Direct

Name: fabG-8 [H]

Synonym: SSO2664

Alternate gene names: 15899387

Gene position: 2420871-2421629 (Clockwise)

Preceding gene: 15899385

Following gene: 15899389

Centisome position: 80.9

GC content: 37.02

Gene sequence:

>759_bases
ATGATAAAGCTAGATCTGAGCGGAAAAGTCTGCCTCATAACTGGTGGGACTTCTGGCATAGGTCTAAAGACTGCAGAACT
CTTTAGCAAATTGGGCGCAAATGTCTACGTTATAGGTAGGAGAGAAGCTAACTTTCTATCTAAAAACATATATTTTAAAA
AAGTTGATTTAACACGGAGAGAAGATGTTCTCTCATTTATTGAATGGTATGAGAAAAACGTGGGGACAATCCATGTATTG
ATAAATAACGCGTCTCAAAATTCAAGATATTCAGTGCTTGATATCCCAATAAAGGAGTGGGATGAGATGATAAGTCTGAA
CTTAACTGCACCTTTTCTCTTATCAAGAATGGCTGCAAAGTTGATGATTAAAAGAGGTATTAAGGGAAAAATAATTAATA
TCTCAGCAATCCAATCGAAGTTTCCATTAGAGAGATCCTTCGCCTATGTTACTACTAAAGGAGGATTAATATCTATGGGA
AGGAGTCTTGCGGTGGATTTAGGAAAATACGGGATACAAGTAATTACTGTATTACCTGGGCCAATTTATTCAAAAGATGA
CGAACCTCCAGCAAGTTTAGATAAGAGAGCAGCTACTCTGTTGGGAAGAATGGGAAGGATGATCGAAATATCCCATTTAT
TAGCCTTTTTAGCTTCAGATTTGAATAGCTTCATCACCGGAACGGAAATTATAATTGATGGAGGTAGAATAATAAGCAGA
AAACCGGATCCAGAAGAAATTACCAAGGGCGAGATATAA

Upstream 100 bases:

>100_bases
TATCCATTTACTTATAGATAAGTACTCATAGCTATTGAAAACTATATAATAGCATAAAATATCTAAAAATTTATTTATTT
AGGTTTAAGATAATTCATGT

Downstream 100 bases:

>100_bases
CTAATAGTCTCTCCAAGTTCCTTTAACTACCCACACTGGTTCTTCTGGATTAAAGTACTCCTCACCTTTAACCTTTAAAC
TATCTAACATTTTCTCATTT

Product: 3-oxoacyl-(acyl carrier protein) reductase (fabG-8)

Products: NA

Alternate protein names: 5-keto-D-gluconate 5-reductase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MIKLDLSGKVCLITGGTSGIGLKTAELFSKLGANVYVIGRREANFLSKNIYFKKVDLTRREDVLSFIEWYEKNVGTIHVL
INNASQNSRYSVLDIPIKEWDEMISLNLTAPFLLSRMAAKLMIKRGIKGKIINISAIQSKFPLERSFAYVTTKGGLISMG
RSLAVDLGKYGIQVITVLPGPIYSKDDEPPASLDKRAATLLGRMGRMIEISHLLAFLASDLNSFITGTEIIIDGGRIISR
KPDPEEITKGEI

Sequences:

>Translated_252_residues
MIKLDLSGKVCLITGGTSGIGLKTAELFSKLGANVYVIGRREANFLSKNIYFKKVDLTRREDVLSFIEWYEKNVGTIHVL
INNASQNSRYSVLDIPIKEWDEMISLNLTAPFLLSRMAAKLMIKRGIKGKIINISAIQSKFPLERSFAYVTTKGGLISMG
RSLAVDLGKYGIQVITVLPGPIYSKDDEPPASLDKRAATLLGRMGRMIEISHLLAFLASDLNSFITGTEIIIDGGRIISR
KPDPEEITKGEI
>Mature_252_residues
MIKLDLSGKVCLITGGTSGIGLKTAELFSKLGANVYVIGRREANFLSKNIYFKKVDLTRREDVLSFIEWYEKNVGTIHVL
INNASQNSRYSVLDIPIKEWDEMISLNLTAPFLLSRMAAKLMIKRGIKGKIINISAIQSKFPLERSFAYVTTKGGLISMG
RSLAVDLGKYGIQVITVLPGPIYSKDDEPPASLDKRAATLLGRMGRMIEISHLLAFLASDLNSFITGTEIIIDGGRIISR
KPDPEEITKGEI

Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=29.0983606557377, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI40254992, Length=233, Percent_Identity=27.8969957081545, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=26.6932270916335, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=27.8225806451613, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=29.2682926829268, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI59889578, Length=194, Percent_Identity=30.4123711340206, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI4758504, Length=250, Percent_Identity=26.8, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI19923817, Length=275, Percent_Identity=27.6363636363636, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI66933014, Length=246, Percent_Identity=30.0813008130081, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=27.0491803278689, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI4503301, Length=249, Percent_Identity=27.3092369477912, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI83715985, Length=249, Percent_Identity=26.1044176706827, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=27.9187817258883, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7706318, Length=196, Percent_Identity=27.0408163265306, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI126723191, Length=179, Percent_Identity=27.3743016759777, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI33667109, Length=187, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=29.7619047619048, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=32.5396825396825, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=28.2868525896414, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=30.9917355371901, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI87082100, Length=265, Percent_Identity=28.6792452830189, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI2367365, Length=237, Percent_Identity=30.8016877637131, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=25.3061224489796, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1789057, Length=201, Percent_Identity=26.865671641791, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=26.2096774193548, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=25.4980079681275, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=25.8964143426295, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=240, Percent_Identity=30.8333333333333, Blast_Score=103, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI25147288, Length=242, Percent_Identity=31.404958677686, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=31.0344827586207, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=27.9693486590038, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=28.8, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=30.1204819277108, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=30.5220883534137, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=32.319391634981, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=28.1954887218045, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=27.0161290322581, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=27.4193548387097, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=27.2030651340996, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=31.2977099236641, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=32.3076923076923, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=29.0076335877863, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=28.1853281853282, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=28.4615384615385, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=28.2945736434109, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=29.3436293436293, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=27.1375464684015, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=27.1317829457364, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=26.4, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=26, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71997099, Length=207, Percent_Identity=26.5700483091787, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=258, Percent_Identity=26.3565891472868, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=26.6917293233083, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=31.7073170731707, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=28.9156626506024, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=30.952380952381, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=29.1497975708502, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=28.7449392712551, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=28.6290322580645, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24644337, Length=254, Percent_Identity=29.9212598425197, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17737361, Length=246, Percent_Identity=25.609756097561, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=27.7551020408163, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=27.319587628866, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.69 [H]

Molecular weight: Translated: 27822; Mature: 27822

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLDLSGKVCLITGGTSGIGLKTAELFSKLGANVYVIGRREANFLSKNIYFKKVDLTRR
CEEEECCCCEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHCCEEEEEECCCHH
EDVLSFIEWYEKNVGTIHVLINNASQNSRYSVLDIPIKEWDEMISLNLTAPFLLSRMAAK
HHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCHHHHHHHEEECCCHHHHHHHHHHH
LMIKRGIKGKIINISAIQSKFPLERSFAYVTTKGGLISMGRSLAVDLGKYGIQVITVLPG
HHHHCCCCCEEEEEEEHHCCCCCCCCEEEEEECCCHHHCCHHHHHHHCCCCEEEEEECCC
PIYSKDDEPPASLDKRAATLLGRMGRMIEISHLLAFLASDLNSFITGTEIIIDGGRIISR
CCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEECC
KPDPEEITKGEI
CCCHHHHCCCCC
>Mature Secondary Structure
MIKLDLSGKVCLITGGTSGIGLKTAELFSKLGANVYVIGRREANFLSKNIYFKKVDLTRR
CEEEECCCCEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHCCEEEEEECCCHH
EDVLSFIEWYEKNVGTIHVLINNASQNSRYSVLDIPIKEWDEMISLNLTAPFLLSRMAAK
HHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCHHHHHHHEEECCCHHHHHHHHHHH
LMIKRGIKGKIINISAIQSKFPLERSFAYVTTKGGLISMGRSLAVDLGKYGIQVITVLPG
HHHHCCCCCEEEEEEEHHCCCCCCCCEEEEEECCCHHHCCHHHHHHHCCCCEEEEEECCC
PIYSKDDEPPASLDKRAATLLGRMGRMIEISHLLAFLASDLNSFITGTEIIIDGGRIISR
CCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEECC
KPDPEEITKGEI
CCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751271 [H]