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The map label for this gene is cutB-2 [H]

Identifier: 15899362

GI number: 15899362

Start: 2399552

End: 2400400

Strand: Direct

Name: cutB-2 [H]

Synonym: SSO2636

Alternate gene names: 15899362

Gene position: 2399552-2400400 (Clockwise)

Preceding gene: 15899361

Following gene: 15899363

Centisome position: 80.19

GC content: 38.4

Gene sequence:

>849_bases
GTGTATCCGCCAGATTTTACATATGTTAGGGTTAGTAGCTCTGAGGAAGCTACAAAATTTCTAGAATCCCACGACGATGC
AAGGCCTCTAGCTGGAGGACAAAGTTTAATTCCAATGCTTAAACTTCGTGTAATATCGCCCAATTATATAGTTGACCTAA
ATCCTATAACGTCACTAAGTTATGTAAGAAGTTCCTTTAATTCAACTAAAATTGGTGCTCTAACTCGATATAATGAAATA
CTAAAGAATGATCTAGTAAGGGTAAACGTTCCATTACTTCATCAAGCAGTTAGGGTAGTAGGAGATATGCAAGTTAGAAA
CTTAGGTACTATTGGTGGTAGCGCTGCAAACGCTGATCCATCAGCTGATATCCCCACTGTACTTACTGCGTTAAACGCCG
AAATTATTCTATCCTCAGCATCCGGCAATAGATCAGTTAATGCTCTAGATTTCTTTAAAGGCGCATTCGCCACAGATTTA
AGAAAAGGTGAAATTATCTCTGAAATTGTTTTACCTAACTTGGAGGGATATAGAACAATTTACAAAAAGGTCGTAAGAAG
AGCTGGAGATTTTGCACTTGTATCTCTAGCATTAGCGATAAAATTGAGGCAAAATGAGATAGAGGATATTAGATTAGCTT
ATGGTGGAGTTGGGGAGAGACCATTCAGAGCGTTAGAAGTTGAGAAAAGTGTAATGGGTAAAAGGCTAAATGATGAGTTA
GTAGAGGAAATTGTAAGTAAGGTTTCAAGTCAAGTAAATCCCCCTTCCGATACTAGGGGGAGTTCTTGGTATAGGAGGGA
GGTTATGAAGGTTATAACTAGAAAAGCCTTAAAGGAGGTGTCGGGTTAA

Upstream 100 bases:

>100_bases
ATTTGAATGTAGAGAAATAATTAAACATTTTATTACCTAATATTCCTAGCTAAACATTTTTTACGTGATAAAATAAATAG
CTAAGAGTGCAATATAATAT

Downstream 100 bases:

>100_bases
ATGTTAATGGTTAATCAAGGAGAGAAAATTAAAATAAAAGTTAAGGTAAATGGAGTATTGTATGAGAGATATGTAAGTCC
AAGGATACTATTAGTTGACT

Product: carbon monoxide dehydrogenase, medium chain. (cutB-2)

Products: NA

Alternate protein names: CO dehydrogenase subunit M; CO-DH M [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MYPPDFTYVRVSSSEEATKFLESHDDARPLAGGQSLIPMLKLRVISPNYIVDLNPITSLSYVRSSFNSTKIGALTRYNEI
LKNDLVRVNVPLLHQAVRVVGDMQVRNLGTIGGSAANADPSADIPTVLTALNAEIILSSASGNRSVNALDFFKGAFATDL
RKGEIISEIVLPNLEGYRTIYKKVVRRAGDFALVSLALAIKLRQNEIEDIRLAYGGVGERPFRALEVEKSVMGKRLNDEL
VEEIVSKVSSQVNPPSDTRGSSWYRREVMKVITRKALKEVSG

Sequences:

>Translated_282_residues
MYPPDFTYVRVSSSEEATKFLESHDDARPLAGGQSLIPMLKLRVISPNYIVDLNPITSLSYVRSSFNSTKIGALTRYNEI
LKNDLVRVNVPLLHQAVRVVGDMQVRNLGTIGGSAANADPSADIPTVLTALNAEIILSSASGNRSVNALDFFKGAFATDL
RKGEIISEIVLPNLEGYRTIYKKVVRRAGDFALVSLALAIKLRQNEIEDIRLAYGGVGERPFRALEVEKSVMGKRLNDEL
VEEIVSKVSSQVNPPSDTRGSSWYRREVMKVITRKALKEVSG
>Mature_282_residues
MYPPDFTYVRVSSSEEATKFLESHDDARPLAGGQSLIPMLKLRVISPNYIVDLNPITSLSYVRSSFNSTKIGALTRYNEI
LKNDLVRVNVPLLHQAVRVVGDMQVRNLGTIGGSAANADPSADIPTVLTALNAEIILSSASGNRSVNALDFFKGAFATDL
RKGEIISEIVLPNLEGYRTIYKKVVRRAGDFALVSLALAIKLRQNEIEDIRLAYGGVGERPFRALEVEKSVMGKRLNDEL
VEEIVSKVSSQVNPPSDTRGSSWYRREVMKVITRKALKEVSG

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=278, Percent_Identity=23.3812949640288, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1789231, Length=281, Percent_Identity=25.6227758007117, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17540638, Length=298, Percent_Identity=25.1677852348993, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 31052; Mature: 31052

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPPDFTYVRVSSSEEATKFLESHDDARPLAGGQSLIPMLKLRVISPNYIVDLNPITSLS
CCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEECCCEEEECCCHHHHH
YVRSSFNSTKIGALTRYNEILKNDLVRVNVPLLHQAVRVVGDMQVRNLGTIGGSAANADP
HHHHCCCCCHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SADIPTVLTALNAEIILSSASGNRSVNALDFFKGAFATDLRKGEIISEIVLPNLEGYRTI
CCCHHHHHHHHCHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHH
YKKVVRRAGDFALVSLALAIKLRQNEIEDIRLAYGGVGERPFRALEVEKSVMGKRLNDEL
HHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHH
VEEIVSKVSSQVNPPSDTRGSSWYRREVMKVITRKALKEVSG
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYPPDFTYVRVSSSEEATKFLESHDDARPLAGGQSLIPMLKLRVISPNYIVDLNPITSLS
CCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEECCCEEEECCCHHHHH
YVRSSFNSTKIGALTRYNEILKNDLVRVNVPLLHQAVRVVGDMQVRNLGTIGGSAANADP
HHHHCCCCCHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SADIPTVLTALNAEIILSSASGNRSVNALDFFKGAFATDLRKGEIISEIVLPNLEGYRTI
CCCHHHHHHHHCHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHH
YKKVVRRAGDFALVSLALAIKLRQNEIEDIRLAYGGVGERPFRALEVEKSVMGKRLNDEL
HHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHH
VEEIVSKVSSQVNPPSDTRGSSWYRREVMKVITRKALKEVSG
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 1510563; 2818128; 10430865; 12475995 [H]