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The map label for this gene is acaB-7 [C]

Identifier: 15899350

GI number: 15899350

Start: 2390314

End: 2391477

Strand: Direct

Name: acaB-7 [C]

Synonym: SSO2625

Alternate gene names: 15899350

Gene position: 2390314-2391477 (Clockwise)

Preceding gene: 15899339

Following gene: 15899351

Centisome position: 79.88

GC content: 41.41

Gene sequence:

>1164_bases
ATGACAAGAAGGGTAGCTGTAATAGGAGTAGGTAATTCGAAGTTCGGGAGAAGAGATGACGTTTCTATTCAAGAGTTAGC
CTGGGAATCTATTAAAGAAGCGTTGAATGATAGTGGTGTATCTCAAAGTGATATAGGACTAGTGGTTATAGGTAGCACTG
CCTATAGAGGTATTGAATTATACCCTGCTCCAATCGTTGCTGAGTATTCTGGACTAACAGGCAAAGTTCCTCTACGCGTT
GAGGCAATGTGCGCTACAGGATTAGCTGCAGCCTTATCCGCATATACTGCAGTAGCTTCAGGTTTAGTTGATATTGCTAT
GGCAGTAGGAGTTGATAAGATGACTGAAGTTGACACCTCAACATCGTTAGCAATAGGCGGAAGAGGGGGTAATTATCAGT
GGGAATATCATTTCTATGGGACCACATTCCCAACTTATTACGCACTTTATGCAACAAGACATATGGCAGTTTTTGGCACA
ACTGAGGAGCAAATGGCTCTAGTTTCGGTAAAGGCGCATAAGTATGGTTCAATGAACCCTAAAGCTCACTTTCAAAAACC
GGTTACCGTAGAAGAAGTTCTCAAGTCCAGAGTAATCTCTTGGCCAATAAAGTTACTTGACTCTTGTCCAATAAGTGATG
GTTCCGCCACTGCAGTATTTGCATCGGAGGAGAAAGTGAAGGAGTTGAAGATTGATTCTCCAGTTTGGATAACTGGAATT
GGTTATGCGAATGATTACGCTTATGTTGCAAGAAGAGGAGAATGGGTGGGATTTAAGGCAACTCAGTTAGCTGCAAGGCA
AGCTTATGAGATGGCTAAGGTAACTCCTAATGATATAGAAGTAGCTACGGTACATGACGCGTTTACAATAGCTGAGATAA
TGGGATATGAGGATTTAGGTTTTACCGAAAAGGGAAAAGGAGGCAAGTTTATAGAAGAGGGGCAAAGCGAGAAAGGTGGA
AAAGTAGGAGTAAATCTATTTGGTGGTCTAAAAGCTAAGGGGCATCCATTAGGAGCTACTGGACTTTCTATGATTTATGA
GATAACTAAACAATTGAGAGATGAAGCTGACAAATTACAACAACCCCTTAAGAAGTATATTGGGCTTGTTCACAATGTAG
GTGGCACAGGTCACTTTGCATATGTTATGATTCTAAGAAGGTGA

Upstream 100 bases:

>100_bases
TTGTATTGTACTATACATATATATGTAATTCACCTGCATATAGTACTATTCGCAAAAGTTTATATAGTTTAGTATTGTAA
GAAATCATGGTTAATCCAAT

Downstream 100 bases:

>100_bases
CCTTAGATGCAAATAGATGCAATACCGTTATCAATAAAATATAAGATCAAATACCCGGACGAATTTATTGAAGCAGTTAA
GAGGGGAGAAATTGTAGCTA

Product: acetyl-CoA acetyltransferase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MTRRVAVIGVGNSKFGRRDDVSIQELAWESIKEALNDSGVSQSDIGLVVIGSTAYRGIELYPAPIVAEYSGLTGKVPLRV
EAMCATGLAAALSAYTAVASGLVDIAMAVGVDKMTEVDTSTSLAIGGRGGNYQWEYHFYGTTFPTYYALYATRHMAVFGT
TEEQMALVSVKAHKYGSMNPKAHFQKPVTVEEVLKSRVISWPIKLLDSCPISDGSATAVFASEEKVKELKIDSPVWITGI
GYANDYAYVARRGEWVGFKATQLAARQAYEMAKVTPNDIEVATVHDAFTIAEIMGYEDLGFTEKGKGGKFIEEGQSEKGG
KVGVNLFGGLKAKGHPLGATGLSMIYEITKQLRDEADKLQQPLKKYIGLVHNVGGTGHFAYVMILRR

Sequences:

>Translated_387_residues
MTRRVAVIGVGNSKFGRRDDVSIQELAWESIKEALNDSGVSQSDIGLVVIGSTAYRGIELYPAPIVAEYSGLTGKVPLRV
EAMCATGLAAALSAYTAVASGLVDIAMAVGVDKMTEVDTSTSLAIGGRGGNYQWEYHFYGTTFPTYYALYATRHMAVFGT
TEEQMALVSVKAHKYGSMNPKAHFQKPVTVEEVLKSRVISWPIKLLDSCPISDGSATAVFASEEKVKELKIDSPVWITGI
GYANDYAYVARRGEWVGFKATQLAARQAYEMAKVTPNDIEVATVHDAFTIAEIMGYEDLGFTEKGKGGKFIEEGQSEKGG
KVGVNLFGGLKAKGHPLGATGLSMIYEITKQLRDEADKLQQPLKKYIGLVHNVGGTGHFAYVMILRR
>Mature_386_residues
TRRVAVIGVGNSKFGRRDDVSIQELAWESIKEALNDSGVSQSDIGLVVIGSTAYRGIELYPAPIVAEYSGLTGKVPLRVE
AMCATGLAAALSAYTAVASGLVDIAMAVGVDKMTEVDTSTSLAIGGRGGNYQWEYHFYGTTFPTYYALYATRHMAVFGTT
EEQMALVSVKAHKYGSMNPKAHFQKPVTVEEVLKSRVISWPIKLLDSCPISDGSATAVFASEEKVKELKIDSPVWITGIG
YANDYAYVARRGEWVGFKATQLAARQAYEMAKVTPNDIEVATVHDAFTIAEIMGYEDLGFTEKGKGGKFIEEGQSEKGGK
VGVNLFGGLKAKGHPLGATGLSMIYEITKQLRDEADKLQQPLKKYIGLVHNVGGTGHFAYVMILRR

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=394, Percent_Identity=34.010152284264, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI302344760, Length=386, Percent_Identity=32.3834196891192, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI302344767, Length=317, Percent_Identity=34.384858044164, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI302344762, Length=379, Percent_Identity=31.6622691292876, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI55956775, Length=346, Percent_Identity=30.3468208092486, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17537653, Length=391, Percent_Identity=29.923273657289, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24585051, Length=406, Percent_Identity=32.512315270936, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI19921506, Length=410, Percent_Identity=33.6585365853659, Blast_Score=173, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 41892; Mature: 41761

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRVAVIGVGNSKFGRRDDVSIQELAWESIKEALNDSGVSQSDIGLVVIGSTAYRGIEL
CCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEE
YPAPIVAEYSGLTGKVPLRVEAMCATGLAAALSAYTAVASGLVDIAMAVGVDKMTEVDTS
ECCCEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
TSLAIGGRGGNYQWEYHFYGTTFPTYYALYATRHMAVFGTTEEQMALVSVKAHKYGSMNP
CEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHEEEEEECCHHHEEEEEEEHHCCCCCCC
KAHFQKPVTVEEVLKSRVISWPIKLLDSCPISDGSATAVFASEEKVKELKIDSPVWITGI
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHEECCCCEEEEEC
GYANDYAYVARRGEWVGFKATQLAARQAYEMAKVTPNDIEVATVHDAFTIAEIMGYEDLG
CCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHCCCCCC
FTEKGKGGKFIEEGQSEKGGKVGVNLFGGLKAKGHPLGATGLSMIYEITKQLRDEADKLQ
CCCCCCCCCHHHCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QPLKKYIGLVHNVGGTGHFAYVMILRR
HHHHHHHHHHHCCCCCCCEEEEEEEEC
>Mature Secondary Structure 
TRRVAVIGVGNSKFGRRDDVSIQELAWESIKEALNDSGVSQSDIGLVVIGSTAYRGIEL
CCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEE
YPAPIVAEYSGLTGKVPLRVEAMCATGLAAALSAYTAVASGLVDIAMAVGVDKMTEVDTS
ECCCEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
TSLAIGGRGGNYQWEYHFYGTTFPTYYALYATRHMAVFGTTEEQMALVSVKAHKYGSMNP
CEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHEEEEEECCHHHEEEEEEEHHCCCCCCC
KAHFQKPVTVEEVLKSRVISWPIKLLDSCPISDGSATAVFASEEKVKELKIDSPVWITGI
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHEECCCCEEEEEC
GYANDYAYVARRGEWVGFKATQLAARQAYEMAKVTPNDIEVATVHDAFTIAEIMGYEDLG
CCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHCCCCCC
FTEKGKGGKFIEEGQSEKGGKVGVNLFGGLKAKGHPLGATGLSMIYEITKQLRDEADKLQ
CCCCCCCCCHHHCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QPLKKYIGLVHNVGGTGHFAYVMILRR
HHHHHHHHHHHCCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: Acyl group transfer; Claisen condensation [C]

Inhibitor: Tris (hydroxy methyl) aminomethane [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]