Click here to switch to the map view.

The map label for this gene is paaF-6 [H]

Identifier: 15899348

GI number: 15899348

Start: 2388719

End: 2389468

Strand: Reverse

Name: paaF-6 [H]

Synonym: SSO2623

Alternate gene names: 15899348

Gene position: 2389468-2388719 (Counterclockwise)

Preceding gene: 15899349

Following gene: 15899347

Centisome position: 79.86

GC content: 37.2

Gene sequence:

>750_bases
ATGATAAAAGTAGATAATAAAGATGGGTACGTAGTAGTTACAATAAGTAGAGCTGATAAATTAAACGCGTTGAACTTGGA
AATGAGAAATGAACTGATATCAAAACTTAAAGAAATTAACGCTAATCCGAAAATTAGAACTGTAATACTGACTGGTGAAG
GAAGGGCATTCTGCGTAGGGGCTGACGTAAATGAGTTCGCCCCAGATTTTACGATAGACTTACGGGAGACGTTTTATCCA
ATAATTAGGGAGATACGTTTTTCAGATAAAATTTACATAGCTGCAATAAATGGTGTTACAGCTGGAGCTTGTATAGGGAT
AAGCTTATCTACAGATTTCAAATTCGCTAAGCGTGAAGTCAAATTCGTTACTGCATTTCAAAGACTTGGATTAGCTTCAG
ACACTGGAGTAGCGTACTTCCTTTTGAAGCTGACTAGAGATCAAAGAGCCTATGAGATTGCTGTCCTAGGAGGGGAATTT
ACTGCAGAGGATGCCGAGAGATGGGGATTGTTGAAGATATCGGAAAATCCACTTTACGACGCTGAGGAAATGGCTAATAA
AATCCTAAATGGTCCATTCCAGTCTTATATTGCTGGAAAGAGAATGGCTAATTTAGTATTGTATAATGATCTAGAAAGGT
TTTTAGAGTACGAATCCGCCATACAAGGTTATTTAGGAAAAACTGAGGACTTTAAGGAAGGTATATCATCATTCAAAGAG
AAAAGAGAGCCTAAATTTAAGGGAGTTTAA

Upstream 100 bases:

>100_bases
TTAGACTTCGAAAGAAGGAATTTCTATTTGGCTTTAAATACAAAAGAGGCTAAAGAAGGTATGAGAGCGTTTTTAGAGAA
GAGAAAACCTAGGTGGGAGA

Downstream 100 bases:

>100_bases
ATAATGAAAGAGAGTCCTTTTCTTAAATTTCTTAACATAGAATTGGAGGAGATAAGGGAAGGTTACGCTAGGGTTTCTGG
AGTTGTGGCTAAAGATTTCT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MIKVDNKDGYVVVTISRADKLNALNLEMRNELISKLKEINANPKIRTVILTGEGRAFCVGADVNEFAPDFTIDLRETFYP
IIREIRFSDKIYIAAINGVTAGACIGISLSTDFKFAKREVKFVTAFQRLGLASDTGVAYFLLKLTRDQRAYEIAVLGGEF
TAEDAERWGLLKISENPLYDAEEMANKILNGPFQSYIAGKRMANLVLYNDLERFLEYESAIQGYLGKTEDFKEGISSFKE
KREPKFKGV

Sequences:

>Translated_249_residues
MIKVDNKDGYVVVTISRADKLNALNLEMRNELISKLKEINANPKIRTVILTGEGRAFCVGADVNEFAPDFTIDLRETFYP
IIREIRFSDKIYIAAINGVTAGACIGISLSTDFKFAKREVKFVTAFQRLGLASDTGVAYFLLKLTRDQRAYEIAVLGGEF
TAEDAERWGLLKISENPLYDAEEMANKILNGPFQSYIAGKRMANLVLYNDLERFLEYESAIQGYLGKTEDFKEGISSFKE
KREPKFKGV
>Mature_249_residues
MIKVDNKDGYVVVTISRADKLNALNLEMRNELISKLKEINANPKIRTVILTGEGRAFCVGADVNEFAPDFTIDLRETFYP
IIREIRFSDKIYIAAINGVTAGACIGISLSTDFKFAKREVKFVTAFQRLGLASDTGVAYFLLKLTRDQRAYEIAVLGGEF
TAEDAERWGLLKISENPLYDAEEMANKILNGPFQSYIAGKRMANLVLYNDLERFLEYESAIQGYLGKTEDFKEGISSFKE
KREPKFKGV

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594469, Length=185, Percent_Identity=29.7297297297297, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI37594471, Length=185, Percent_Identity=29.7297297297297, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI194097323, Length=240, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787660, Length=250, Percent_Identity=34, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787659, Length=249, Percent_Identity=28.5140562248996, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI221142681, Length=248, Percent_Identity=28.2258064516129, Blast_Score=75, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17554946, Length=254, Percent_Identity=25.5905511811024, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI25144160, Length=181, Percent_Identity=33.1491712707182, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI25144157, Length=181, Percent_Identity=33.1491712707182, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=205, Percent_Identity=29.2682926829268, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25145438, Length=240, Percent_Identity=27.0833333333333, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560910, Length=253, Percent_Identity=26.8774703557312, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17540306, Length=238, Percent_Identity=28.1512605042017, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536985, Length=189, Percent_Identity=26.4550264550265, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=180, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129971, Length=241, Percent_Identity=27.8008298755187, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24653477, Length=241, Percent_Identity=27.8008298755187, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28059; Mature: 28059

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVDNKDGYVVVTISRADKLNALNLEMRNELISKLKEINANPKIRTVILTGEGRAFCVG
CEEECCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEE
ADVNEFAPDFTIDLRETFYPIIREIRFSDKIYIAAINGVTAGACIGISLSTDFKFAKREV
CCHHHHCCCCEEEHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEECCCHHHHHHHH
KFVTAFQRLGLASDTGVAYFLLKLTRDQRAYEIAVLGGEFTAEDAERWGLLKISENPLYD
HHHHHHHHCCCCCCCCHHEEEEEHHCCCCEEEEEEECCCCCCCCHHHCCEEEECCCCCCC
AEEMANKILNGPFQSYIAGKRMANLVLYNDLERFLEYESAIQGYLGKTEDFKEGISSFKE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KREPKFKGV
HCCCCCCCC
>Mature Secondary Structure
MIKVDNKDGYVVVTISRADKLNALNLEMRNELISKLKEINANPKIRTVILTGEGRAFCVG
CEEECCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEE
ADVNEFAPDFTIDLRETFYPIIREIRFSDKIYIAAINGVTAGACIGISLSTDFKFAKREV
CCHHHHCCCCEEEHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEECCCHHHHHHHH
KFVTAFQRLGLASDTGVAYFLLKLTRDQRAYEIAVLGGEFTAEDAERWGLLKISENPLYD
HHHHHHHHCCCCCCCCHHEEEEEHHCCCCEEEEEEECCCCCCCCHHHCCEEEECCCCCCC
AEEMANKILNGPFQSYIAGKRMANLVLYNDLERFLEYESAIQGYLGKTEDFKEGISSFKE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KREPKFKGV
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]