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The map label for this gene is agxT

Identifier: 15899324

GI number: 15899324

Start: 2361442

End: 2362596

Strand: Reverse

Name: agxT

Synonym: SSO2597

Alternate gene names: NA

Gene position: 2362596-2361442 (Counterclockwise)

Preceding gene: 15899325

Following gene: 15899322

Centisome position: 78.96

GC content: 41.13

Gene sequence:

>1155_bases
ATGGATAAACTGCTACTTCATGTAGGCCCTACTACTATCAAGGAAGATGTTTTAGTTGCGGGGCTTGAAAATAACGTTGG
CTTTACTTCTAAAGAATTCGTAGAAGCACTGGCATATTCGCTAAAGGGATTAAGATATGTAATGGGTGCAAGTAAGAACT
ATCAGCCATTAATAATCCCTGGAGGTGGAACATCTGCTATGGAAAGTGTTACATCATTGCTCAAACCTAATGATAAAATA
CTAGTAGTTTCGAATGGAGTTTTTGGTGATAGATGGGAGCAAATATTCAAGAGATATCCAGTTAATGTAAAGGTATTAAG
ACCTTCTCCTGGCGATTACGTTAAACCAGGGGAGGTTGAGGAAGAAGTTAGGAAGAGTGAGTATAAGTTAGTTGCCTTGA
CTCACGTAGAGACTAGCACCGGAGTTAGAGAGCCAGTAAAGGATGTGATAAATAAAATAAGAAAATACGTAGAGCTGATA
GTGGTAGACGGTGTTTCAAGCGTTGGGGCTGAGGAAGTTAAGGCTGAAGAATGGAATGTCGACGTTTATCTGACAGCCAG
TCAAAAGGCATTGGGTTCGGCAGCTGGTTTAGGCTTGCTATTACTTTCTCCTAAGGCTTTATCAATATTGGATTCCCAAA
ATTCAATCGCCGGGTATTATCTGGATTTAAGAAATTGGCTACCAGTTATGAGAGGGGCTGAAGAAGGTAAGGCTGCTTAT
TTTGCTACTCCTCCAGTTCATGTAATTTTACAATTAGCCGAAGCCTTTAGACTGATAGAGAAAGAAGGTATAGAAAATAG
AATAAAAAGACACACAATGGTAGCTAGCGCAATTAGGGCTGGCTTAGAAGCTTTAGGATTAGAGATAGTAGCCAGAAGAC
CAGAGTCTTATAGTAATACTGTAACTGGAGTAATCCTAAAGGTTGCGGACCCACAAAAGGTTCTCGCGGGGACCGTTAAT
GAGGGGGTAGAATTTGCACCTGGAGTCCATCCTGCATTTAAATATTTCAGAATAGGTCATATGGGCTGGGTAACGCCCAA
CGATGCGATAATTGCAATAAGTGTCATTGAGAGAACCCTAAGGAAATTAGGTGAACCTATAAGGTTTGGTGAAGGAGTAA
AGGCAGTTGAAGAGGTTCTATTCTCAGCCCGCTGA

Upstream 100 bases:

>100_bases
CATCTATATATGAATACATGTTTTGGGACTCTGCGTATAGATTAGAGAGGTTTCCTTTTCCTACAGAAAAAAATAAAGGA
GTGTAACTAACTTACCTTTT

Downstream 100 bases:

>100_bases
AAGTATATCATCAATCTAAATCCCCGAAAATATCATCACTCCCAGTTTTTAAGATAATACCACTAAATATTATAAATATG
ACTGATGTAAGTGGTAACAA

Product: Serine-pyruvate aminotransferase (agxT)

Products: 3-hydroxypyruvate; L-alanine

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MDKLLLHVGPTTIKEDVLVAGLENNVGFTSKEFVEALAYSLKGLRYVMGASKNYQPLIIPGGGTSAMESVTSLLKPNDKI
LVVSNGVFGDRWEQIFKRYPVNVKVLRPSPGDYVKPGEVEEEVRKSEYKLVALTHVETSTGVREPVKDVINKIRKYVELI
VVDGVSSVGAEEVKAEEWNVDVYLTASQKALGSAAGLGLLLLSPKALSILDSQNSIAGYYLDLRNWLPVMRGAEEGKAAY
FATPPVHVILQLAEAFRLIEKEGIENRIKRHTMVASAIRAGLEALGLEIVARRPESYSNTVTGVILKVADPQKVLAGTVN
EGVEFAPGVHPAFKYFRIGHMGWVTPNDAIIAISVIERTLRKLGEPIRFGEGVKAVEEVLFSAR

Sequences:

>Translated_384_residues
MDKLLLHVGPTTIKEDVLVAGLENNVGFTSKEFVEALAYSLKGLRYVMGASKNYQPLIIPGGGTSAMESVTSLLKPNDKI
LVVSNGVFGDRWEQIFKRYPVNVKVLRPSPGDYVKPGEVEEEVRKSEYKLVALTHVETSTGVREPVKDVINKIRKYVELI
VVDGVSSVGAEEVKAEEWNVDVYLTASQKALGSAAGLGLLLLSPKALSILDSQNSIAGYYLDLRNWLPVMRGAEEGKAAY
FATPPVHVILQLAEAFRLIEKEGIENRIKRHTMVASAIRAGLEALGLEIVARRPESYSNTVTGVILKVADPQKVLAGTVN
EGVEFAPGVHPAFKYFRIGHMGWVTPNDAIIAISVIERTLRKLGEPIRFGEGVKAVEEVLFSAR
>Mature_384_residues
MDKLLLHVGPTTIKEDVLVAGLENNVGFTSKEFVEALAYSLKGLRYVMGASKNYQPLIIPGGGTSAMESVTSLLKPNDKI
LVVSNGVFGDRWEQIFKRYPVNVKVLRPSPGDYVKPGEVEEEVRKSEYKLVALTHVETSTGVREPVKDVINKIRKYVELI
VVDGVSSVGAEEVKAEEWNVDVYLTASQKALGSAAGLGLLLLSPKALSILDSQNSIAGYYLDLRNWLPVMRGAEEGKAAY
FATPPVHVILQLAEAFRLIEKEGIENRIKRHTMVASAIRAGLEALGLEIVARRPESYSNTVTGVILKVADPQKVLAGTVN
EGVEFAPGVHPAFKYFRIGHMGWVTPNDAIIAISVIERTLRKLGEPIRFGEGVKAVEEVLFSAR

Specific function: Unknown

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=346, Percent_Identity=30.3468208092486, Blast_Score=152, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17536281, Length=370, Percent_Identity=28.3783783783784, Blast_Score=127, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6321079, Length=359, Percent_Identity=37.6044568245125, Blast_Score=196, Evalue=5e-51,
Organism=Drosophila melanogaster, GI17530823, Length=351, Percent_Identity=27.9202279202279, Blast_Score=115, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.51

Molecular weight: Translated: 41977; Mature: 41977

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLLLHVGPTTIKEDVLVAGLENNVGFTSKEFVEALAYSLKGLRYVMGASKNYQPLIIP
CCCEEEEECCCHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
GGGTSAMESVTSLLKPNDKILVVSNGVFGDRWEQIFKRYPVNVKVLRPSPGDYVKPGEVE
CCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCHH
EEVRKSEYKLVALTHVETSTGVREPVKDVINKIRKYVELIVVDGVSSVGAEEVKAEEWNV
HHHHHCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHCCE
DVYLTASQKALGSAAGLGLLLLSPKALSILDSQNSIAGYYLDLRNWLPVMRGAEEGKAAY
EEEEEECHHHHHHHCCCEEEEECCHHHEEECCCCCCEEEEEEHHHHHHHHCCCCCCCEEE
FATPPVHVILQLAEAFRLIEKEGIENRIKRHTMVASAIRAGLEALGLEIVARRPESYSNT
EECCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VTGVILKVADPQKVLAGTVNEGVEFAPGVHPAFKYFRIGHMGWVTPNDAIIAISVIERTL
EEEEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHEECCCCCCCCCCCEEEHHHHHHHH
RKLGEPIRFGEGVKAVEEVLFSAR
HHCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MDKLLLHVGPTTIKEDVLVAGLENNVGFTSKEFVEALAYSLKGLRYVMGASKNYQPLIIP
CCCEEEEECCCHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
GGGTSAMESVTSLLKPNDKILVVSNGVFGDRWEQIFKRYPVNVKVLRPSPGDYVKPGEVE
CCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCHH
EEVRKSEYKLVALTHVETSTGVREPVKDVINKIRKYVELIVVDGVSSVGAEEVKAEEWNV
HHHHHCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHCCE
DVYLTASQKALGSAAGLGLLLLSPKALSILDSQNSIAGYYLDLRNWLPVMRGAEEGKAAY
EEEEEECHHHHHHHCCCEEEEECCHHHEEECCCCCCEEEEEEHHHHHHHHCCCCCCCEEE
FATPPVHVILQLAEAFRLIEKEGIENRIKRHTMVASAIRAGLEALGLEIVARRPESYSNT
EECCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VTGVILKVADPQKVLAGTVNEGVEFAPGVHPAFKYFRIGHMGWVTPNDAIIAISVIERTL
EEEEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHEECCCCCCCCCCCEEEHHHHHHHH
RKLGEPIRFGEGVKAVEEVLFSAR
HHCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-serine; pyruvate

Specific reaction: L-serine + pyruvate = 3-hydroxypyruvate + L-alanine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]