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The map label for this gene is glpA [H]

Identifier: 15899261

GI number: 15899261

Start: 2294204

End: 2295541

Strand: Reverse

Name: glpA [H]

Synonym: SSO2526

Alternate gene names: 15899261

Gene position: 2295541-2294204 (Counterclockwise)

Preceding gene: 15899262

Following gene: 15899260

Centisome position: 76.72

GC content: 37.52

Gene sequence:

>1338_bases
ATGTCAACATTTTTAATGTTAAATCCACTACACATTATTATGGAGATTAAATCCACGGTAACTGTAATTGGTGGAGGAGT
TAGTGGTTTATTTACCGCCTTAGACTTAGCACTGAGAGGAATTGATGTAACGCTAGTGGATAGAGGTGATATAGGATATG
GGACTTCTGGGAAATTTCACGGTCTTCTTCATAGTGGGGCTAGATATGCTGTAACTGATCCAGATTCGGCTAGGGAGTGC
ATTCAAGAAAATAAAATAATTTCAAAGATAGCTCCTCATACAGTGAAAGATACTGGTGGAGTATTTCTTGGCATCACTGA
TGACGACTTACAGTTCTCTGAAACTTTCATAAAAGCGTTAAATAAAGTGGGGATTGAGAGCAAAGTCATAGACGTTAAGG
AGGTATTACAAAAAGAGCCATTCATTAATAGGGACACAAAGATGGCTATATGGGTTCCCGATAAGGTGGTTTACGGTTAT
GACTTATTGGCAAGCGTTGCAATTACTGCATCGTTAAATGGAGCGAAAATTTTAACGTACAATGAGGTAGTTGAAATCAT
AAGAGAAAATAATAACGTTAAGGGAGTTAAGGTTTTAGATAAAATAAATAACAATACTAACGTGATAAAATCTGACATCA
TAGTTAACACAGCTGGACCTTGGTCATTCAATATAATAAAGATGGCTGGTTTAGAGGAAATACCTATAATGCCAACTGCG
GGAATTATAGTCGTGTTTGATAAAAGGGTTAATAATATGGTAATCAATAGGCTGAGACCACCCTCTGATGGAGATATAAT
TGTCCCATACGCTGACTCATCAATTTTAGGAACTACTGCTACTATTATTGAGGATCCAGACAATTTCACCATATCGGATG
AGGATATTGCCATGCTAGTAAATGAGGGAGCATATCTAATACCAAAATTAAAGAATATGAGGGTAGTTAGGTCATACGCT
TCTGTAAGGCCATTAATTAAGAGCGAAGTCTCGGCTAGGGAGGCTTCAAGAGACTTTAGAATAATAGATCATGAGAAGGA
GAATGGACTAAGTGGACTAGTATCCGTAATAGGCGGTAAGTTCACTACGGGAAGACTAGCTGGAGAAAGAGTGGCTGATT
TAGTTTCCTCAAAACTAGGGATTAAGAGTGCAAGCAAGACAGCTACTACTAAGTTGCTCAGCCCTAATGATATTAACTTA
TTAAATTACGCTGAAAAAATTAGGCTACCTAAAGTAATAGTAAGGAGCATTCTGGATCGTAAAGGATCCTTAGATGAAGA
AAGGTATTTAAGTTCGCTATATATCCTCCTATCGCTAATTTCTAGAGGGACGATGTAG

Upstream 100 bases:

>100_bases
TACATATCACAGCATGGCTTATTCTGACTTTCTCAACGCCCTAAATGGAGAGAGTTATGTAGTAAAATTTGTCAACTGTT
GCTCTCATGCAAGTTAAACT

Downstream 100 bases:

>100_bases
AAATGGAGTTTAAGGGAACTTTTGATGTAAAGAGAACTATAGAGGCCGTCAAGGGATTTTTAATTAATCCAAAACAGTTC
GCTGAATGCCTAACTGGATT

Product: glycerol-3-phosphate dehydrogenase chain A (glpA)

Products: NA

Alternate protein names: G-3-P dehydrogenase [H]

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSTFLMLNPLHIIMEIKSTVTVIGGGVSGLFTALDLALRGIDVTLVDRGDIGYGTSGKFHGLLHSGARYAVTDPDSAREC
IQENKIISKIAPHTVKDTGGVFLGITDDDLQFSETFIKALNKVGIESKVIDVKEVLQKEPFINRDTKMAIWVPDKVVYGY
DLLASVAITASLNGAKILTYNEVVEIIRENNNVKGVKVLDKINNNTNVIKSDIIVNTAGPWSFNIIKMAGLEEIPIMPTA
GIIVVFDKRVNNMVINRLRPPSDGDIIVPYADSSILGTTATIIEDPDNFTISDEDIAMLVNEGAYLIPKLKNMRVVRSYA
SVRPLIKSEVSAREASRDFRIIDHEKENGLSGLVSVIGGKFTTGRLAGERVADLVSSKLGIKSASKTATTKLLSPNDINL
LNYAEKIRLPKVIVRSILDRKGSLDEERYLSSLYILLSLISRGTM

Sequences:

>Translated_445_residues
MSTFLMLNPLHIIMEIKSTVTVIGGGVSGLFTALDLALRGIDVTLVDRGDIGYGTSGKFHGLLHSGARYAVTDPDSAREC
IQENKIISKIAPHTVKDTGGVFLGITDDDLQFSETFIKALNKVGIESKVIDVKEVLQKEPFINRDTKMAIWVPDKVVYGY
DLLASVAITASLNGAKILTYNEVVEIIRENNNVKGVKVLDKINNNTNVIKSDIIVNTAGPWSFNIIKMAGLEEIPIMPTA
GIIVVFDKRVNNMVINRLRPPSDGDIIVPYADSSILGTTATIIEDPDNFTISDEDIAMLVNEGAYLIPKLKNMRVVRSYA
SVRPLIKSEVSAREASRDFRIIDHEKENGLSGLVSVIGGKFTTGRLAGERVADLVSSKLGIKSASKTATTKLLSPNDINL
LNYAEKIRLPKVIVRSILDRKGSLDEERYLSSLYILLSLISRGTM
>Mature_444_residues
STFLMLNPLHIIMEIKSTVTVIGGGVSGLFTALDLALRGIDVTLVDRGDIGYGTSGKFHGLLHSGARYAVTDPDSARECI
QENKIISKIAPHTVKDTGGVFLGITDDDLQFSETFIKALNKVGIESKVIDVKEVLQKEPFINRDTKMAIWVPDKVVYGYD
LLASVAITASLNGAKILTYNEVVEIIRENNNVKGVKVLDKINNNTNVIKSDIIVNTAGPWSFNIIKMAGLEEIPIMPTAG
IIVVFDKRVNNMVINRLRPPSDGDIIVPYADSSILGTTATIIEDPDNFTISDEDIAMLVNEGAYLIPKLKNMRVVRSYAS
VRPLIKSEVSAREASRDFRIIDHEKENGLSGLVSVIGGKFTTGRLAGERVADLVSSKLGIKSASKTATTKLLSPNDINLL
NYAEKIRLPKVIVRSILDRKGSLDEERYLSSLYILLSLISRGTM

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Fumarate Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=457, Percent_Identity=26.0393873085339, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI285002231, Length=457, Percent_Identity=26.0393873085339, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1788574, Length=418, Percent_Identity=38.9952153110048, Blast_Score=285, Evalue=3e-78,
Organism=Caenorhabditis elegans, GI17509253, Length=402, Percent_Identity=27.1144278606965, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI115534726, Length=373, Percent_Identity=27.0777479892761, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322036, Length=410, Percent_Identity=26.3414634146341, Blast_Score=93, Evalue=7e-20,
Organism=Drosophila melanogaster, GI161077125, Length=407, Percent_Identity=27.5184275184275, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24653942, Length=407, Percent_Identity=27.5184275184275, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24653944, Length=407, Percent_Identity=27.5184275184275, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI20130025, Length=407, Percent_Identity=27.5184275184275, Blast_Score=95, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007419
- InterPro:   IPR006076
- InterPro:   IPR017752
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO; PF04324 Fer2_BFD [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 48645; Mature: 48514

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFLMLNPLHIIMEIKSTVTVIGGGVSGLFTALDLALRGIDVTLVDRGDIGYGTSGKFH
CCCEEEECHHHEEHHHHCEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEE
GLLHSGARYAVTDPDSARECIQENKIISKIAPHTVKDTGGVFLGITDDDLQFSETFIKAL
EEECCCCEEEECCCHHHHHHHHHCHHHHHHCCCCEECCCCEEEEECCCCCHHHHHHHHHH
NKVGIESKVIDVKEVLQKEPFINRDTKMAIWVPDKVVYGYDLLASVAITASLNGAKILTY
HHCCCCCEEEHHHHHHHHCCCCCCCCEEEEECCCCEEHHHHHHHHHHHEEECCCCEEEEH
NEVVEIIRENNNVKGVKVLDKINNNTNVIKSDIIVNTAGPWSFNIIKMAGLEEIPIMPTA
HHHHHHHHCCCCCCEEEHEECCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCC
GIIVVFDKRVNNMVINRLRPPSDGDIIVPYADSSILGTTATIIEDPDNFTISDEDIAMLV
CEEEEEECHHHHHHHHCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCEECCCCEEEEE
NEGAYLIPKLKNMRVVRSYASVRPLIKSEVSAREASRDFRIIDHEKENGLSGLVSVIGGK
CCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCC
FTTGRLAGERVADLVSSKLGIKSASKTATTKLLSPNDINLLNYAEKIRLPKVIVRSILDR
CCCCHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCCCCHHHHHHHHCCHHHHHHHHHHC
KGSLDEERYLSSLYILLSLISRGTM
CCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STFLMLNPLHIIMEIKSTVTVIGGGVSGLFTALDLALRGIDVTLVDRGDIGYGTSGKFH
CCEEEECHHHEEHHHHCEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEE
GLLHSGARYAVTDPDSARECIQENKIISKIAPHTVKDTGGVFLGITDDDLQFSETFIKAL
EEECCCCEEEECCCHHHHHHHHHCHHHHHHCCCCEECCCCEEEEECCCCCHHHHHHHHHH
NKVGIESKVIDVKEVLQKEPFINRDTKMAIWVPDKVVYGYDLLASVAITASLNGAKILTY
HHCCCCCEEEHHHHHHHHCCCCCCCCEEEEECCCCEEHHHHHHHHHHHEEECCCCEEEEH
NEVVEIIRENNNVKGVKVLDKINNNTNVIKSDIIVNTAGPWSFNIIKMAGLEEIPIMPTA
HHHHHHHHCCCCCCEEEHEECCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCC
GIIVVFDKRVNNMVINRLRPPSDGDIIVPYADSSILGTTATIIEDPDNFTISDEDIAMLV
CEEEEEECHHHHHHHHCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCEECCCCEEEEE
NEGAYLIPKLKNMRVVRSYASVRPLIKSEVSAREASRDFRIIDHEKENGLSGLVSVIGGK
CCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCC
FTTGRLAGERVADLVSSKLGIKSASKTATTKLLSPNDINLLNYAEKIRLPKVIVRSILDR
CCCCHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCCCCHHHHHHHHCCHHHHHHHHHHC
KGSLDEERYLSSLYILLSLISRGTM
CCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]